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Humoral immune response to COVID-19 vaccine in patients with myasthenia gravis. / Holm-Yildiz, Sonja; Dysgaard, Tina; Krag, Thomas; Pedersen, Britt Stævnsbo; Hamm, Sebastian Rask; Pérez-Alós, Laura; Hansen, Cecilie Bo; Pries-Heje, Mia Marie; Heftdal, Line Dam; Hasselbalch, Rasmus Bo; Fogh, Kamille; Madsen, Johannes Roth; Frikke-Schmidt, Ruth; Hilsted, Linda Maria; Sørensen, Erik; Ostrowski, Sisse Rye; Bundgaard, Henning; Garred, Peter; Iversen, Kasper; Nielsen, Susanne Dam; Vissing, John.
In:
Journal of Neuroimmunology, Vol. 384, 578215, 2023.
Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
Holm-Yildiz, S, Dysgaard, T, Krag, T, Pedersen, BS, Hamm, SR, Pérez-Alós, L
, Hansen, CB, Pries-Heje, MM
, Heftdal, LD, Hasselbalch, RB, Fogh, K, Madsen, JR
, Frikke-Schmidt, R, Hilsted, LM, Sørensen, E
, Ostrowski, SR, Bundgaard, H, Garred, P, Iversen, K, Nielsen, SD & Vissing, J 2023, '
Humoral immune response to COVID-19 vaccine in patients with myasthenia gravis',
Journal of Neuroimmunology, vol. 384, 578215.
https://doi.org/10.1016/j.jneuroim.2023.578215APA
Holm-Yildiz, S., Dysgaard, T., Krag, T., Pedersen, B. S., Hamm, S. R., Pérez-Alós, L.
, Hansen, C. B., Pries-Heje, M. M.
, Heftdal, L. D., Hasselbalch, R. B., Fogh, K., Madsen, J. R.
, Frikke-Schmidt, R., Hilsted, L. M., Sørensen, E.
, Ostrowski, S. R., Bundgaard, H., Garred, P., Iversen, K., ... Vissing, J. (2023).
Humoral immune response to COVID-19 vaccine in patients with myasthenia gravis.
Journal of Neuroimmunology,
384, [578215].
https://doi.org/10.1016/j.jneuroim.2023.578215Vancouver
Holm-Yildiz S, Dysgaard T, Krag T, Pedersen BS, Hamm SR, Pérez-Alós L et al.
Humoral immune response to COVID-19 vaccine in patients with myasthenia gravis.
Journal of Neuroimmunology. 2023;384. 578215.
https://doi.org/10.1016/j.jneuroim.2023.578215Author
Holm-Yildiz, Sonja ; Dysgaard, Tina ; Krag, Thomas ; Pedersen, Britt Stævnsbo ; Hamm, Sebastian Rask ; Pérez-Alós, Laura ; Hansen, Cecilie Bo ; Pries-Heje, Mia Marie ; Heftdal, Line Dam ; Hasselbalch, Rasmus Bo ; Fogh, Kamille ; Madsen, Johannes Roth ; Frikke-Schmidt, Ruth ; Hilsted, Linda Maria ; Sørensen, Erik ; Ostrowski, Sisse Rye ; Bundgaard, Henning ; Garred, Peter ; Iversen, Kasper ; Nielsen, Susanne Dam ; Vissing, John. / Humoral immune response to COVID-19 vaccine in patients with myasthenia gravis. In: Journal of Neuroimmunology. 2023 ; Vol. 384.
Bibtex
@article{7049852bfd63438ba441f6145b1fb02d,
title = "Humoral immune response to COVID-19 vaccine in patients with myasthenia gravis",
abstract = "We investigated the humoral response to the Pfizer-BioNTech COVID-19 (BNT162b2) vaccine in patients with myasthenia gravis on or off immunosuppressants and compared this to the response in healthy individuals. The SARS-CoV-2 IgG response and neutralizing capacity were measured in 83 patients (57 on immunosuppressants) and 332 healthy controls at baseline, three weeks, and two and six months after the vaccine. We found that the proportion of positive humoral response was lower in patients on immunosuppressants vs. controls at three weeks and two months (p ≤ 0.001), but not at six months post-vaccination (p = 0.379).",
keywords = "BNT162b2, COVID-19 vaccine, Humoral response, Myasthenia gravis",
author = "Sonja Holm-Yildiz and Tina Dysgaard and Thomas Krag and Pedersen, {Britt St{\ae}vnsbo} and Hamm, {Sebastian Rask} and Laura P{\'e}rez-Al{\'o}s and Hansen, {Cecilie Bo} and Pries-Heje, {Mia Marie} and Heftdal, {Line Dam} and Hasselbalch, {Rasmus Bo} and Kamille Fogh and Madsen, {Johannes Roth} and Ruth Frikke-Schmidt and Hilsted, {Linda Maria} and Erik S{\o}rensen and Ostrowski, {Sisse Rye} and Henning Bundgaard and Peter Garred and Kasper Iversen and Nielsen, {Susanne Dam} and John Vissing",
note = "Publisher Copyright: {\textcopyright} 2023 The Authors",
year = "2023",
doi = "10.1016/j.jneuroim.2023.578215",
language = "English",
volume = "384",
journal = "Journal of Neuroimmunology",
issn = "0165-5728",
publisher = "Elsevier",
}
RIS
TY - JOUR
T1 - Humoral immune response to COVID-19 vaccine in patients with myasthenia gravis
AU - Holm-Yildiz, Sonja
AU - Dysgaard, Tina
AU - Krag, Thomas
AU - Pedersen, Britt Stævnsbo
AU - Hamm, Sebastian Rask
AU - Pérez-Alós, Laura
AU - Hansen, Cecilie Bo
AU - Pries-Heje, Mia Marie
AU - Heftdal, Line Dam
AU - Hasselbalch, Rasmus Bo
AU - Fogh, Kamille
AU - Madsen, Johannes Roth
AU - Frikke-Schmidt, Ruth
AU - Hilsted, Linda Maria
AU - Sørensen, Erik
AU - Ostrowski, Sisse Rye
AU - Bundgaard, Henning
AU - Garred, Peter
AU - Iversen, Kasper
AU - Nielsen, Susanne Dam
AU - Vissing, John
N1 - Publisher Copyright:
© 2023 The Authors
PY - 2023
Y1 - 2023
N2 - We investigated the humoral response to the Pfizer-BioNTech COVID-19 (BNT162b2) vaccine in patients with myasthenia gravis on or off immunosuppressants and compared this to the response in healthy individuals. The SARS-CoV-2 IgG response and neutralizing capacity were measured in 83 patients (57 on immunosuppressants) and 332 healthy controls at baseline, three weeks, and two and six months after the vaccine. We found that the proportion of positive humoral response was lower in patients on immunosuppressants vs. controls at three weeks and two months (p ≤ 0.001), but not at six months post-vaccination (p = 0.379).
AB - We investigated the humoral response to the Pfizer-BioNTech COVID-19 (BNT162b2) vaccine in patients with myasthenia gravis on or off immunosuppressants and compared this to the response in healthy individuals. The SARS-CoV-2 IgG response and neutralizing capacity were measured in 83 patients (57 on immunosuppressants) and 332 healthy controls at baseline, three weeks, and two and six months after the vaccine. We found that the proportion of positive humoral response was lower in patients on immunosuppressants vs. controls at three weeks and two months (p ≤ 0.001), but not at six months post-vaccination (p = 0.379).
KW - BNT162b2
KW - COVID-19 vaccine
KW - Humoral response
KW - Myasthenia gravis
U2 - 10.1016/j.jneuroim.2023.578215
DO - 10.1016/j.jneuroim.2023.578215
M3 - Journal article
C2 - 37797472
AN - SCOPUS:85172764956
VL - 384
JO - Journal of Neuroimmunology
JF - Journal of Neuroimmunology
SN - 0165-5728
M1 - 578215
ER -
