Improvement in fetal DNA extraction from maternal plasma. Evaluation of the NucliSens Magnetic Extraction system and the QIAamp DSP Virus Kit in comparison with the QIAamp DNA Blood Mini Kit
Research output: Contribution to journal › Journal article › Research › peer-review
Prenatal diagnostic assays have been developed using free fetal DNA circulating in the maternal blood of pregnant women. Efficient DNA extraction is crucial for a robust analysis. To improve fetal DNA yield, we tested two manual extraction methods--the NucliSens Magnetic Extraction (NMAG) system and the QIAamp DSP Virus Kit (QDSP)--against our current standard method, the widely used QIAamp DNA Blood Mini Kit (QDNA).
| Original language | English |
|---|---|
| Journal | Prenatal Diagnosis |
| Volume | 27 |
| Issue number | 1 |
| Pages (from-to) | 6-10 |
| Number of pages | 5 |
| ISSN | 0197-3851 |
| DOIs | |
| Publication status | Published - Jan 2007 |
- DNA, Exons, Female, Fetal Blood, Fetomaternal Transfusion, Glyceraldehyde-3-Phosphate Dehydrogenases, Humans, Magnetics, Polymerase Chain Reaction, Pregnancy, Prenatal Diagnosis, Reagent Kits, Diagnostic, Rh-Hr Blood-Group System
Research areas
ID: 47556678