In vitro assessment of recombinant, mutant immunoglobulin G anti-D devoid of hemolytic activity for treatment of ongoing hemolytic disease of the fetus and newborn
Research output: Contribution to journal › Journal article › Research › peer-review
A specific treatment for ongoing hemolytic disease of the fetus and newborn (HDFN) due to anti-D would be very attractive. One approach could be administration to the mother of nonhemolytic anti-D, which by crossing the placenta can block the binding of hemolytic maternal anti-D.
| Original language | English |
|---|---|
| Journal | Transfusion |
| Volume | 48 |
| Issue number | 1 |
| Pages (from-to) | 12-9 |
| Number of pages | 8 |
| ISSN | 0041-1132 |
| DOIs | |
| Publication status | Published - 1 Jan 2008 |
- Animals, Antibodies, Anti-Idiotypic, Antibody-Dependent Cell Cytotoxicity, CHO Cells, Chemiluminescent Measurements, Cricetinae, Cricetulus, Erythroblastosis, Fetal, Female, Hemolysis, Humans, Immunoglobulin G, Immunotherapy, Monocytes, Mutation, Recombinant Proteins, Respiratory Burst, Rho(D) Immune Globulin
Research areas
ID: 35155214