Increased Y-chromosome detection by SRY duplexing
Research output: Contribution to journal › Journal article › Research › peer-review
Determining fetal sex noninvasively is dependent of a robust assay. We designed a novel SRY assay and combined it with a SRY assay from literature forming a duplex assay with the same fluorescent dye to increase detection of Y-chromosome at low cell-free fetal DNA or chimeric DNA concentrations.
| Original language | English |
|---|---|
| Journal | Fetal Diagnosis and Therapy |
| Volume | 31 |
| Issue number | 3 |
| Pages (from-to) | 185-90 |
| Number of pages | 6 |
| DOIs | |
| Publication status | Published - 2012 |
- Chromosomes, Human, Y, DNA, Denmark, Female, Fluorescent Dyes, Genes, sry, Gestational Age, Humans, Male, Nucleic Acid Probes, Predictive Value of Tests, Pregnancy, Prenatal Diagnosis, Real-Time Polymerase Chain Reaction, Sensitivity and Specificity, Sex Determination Analysis
Research areas
ID: 47554480