Malariavacciner, en nødvendighed for fremtidig malariakontrol. Status og fremtidsudsigter

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Malariavacciner, en nødvendighed for fremtidig malariakontrol. Status og fremtidsudsigter. / Petersen, E; Høgh, B; Jakobsen, P H; Dziegiel, Morten Hanefeld; Borre, M; Jepsen, S.

In: Ugeskrift for Laeger, Vol. 152, No. 29, 16.07.1990, p. 2092-5.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Petersen, E, Høgh, B, Jakobsen, PH, Dziegiel, MH, Borre, M & Jepsen, S 1990, 'Malariavacciner, en nødvendighed for fremtidig malariakontrol. Status og fremtidsudsigter', Ugeskrift for Laeger, vol. 152, no. 29, pp. 2092-5.

APA

Petersen, E., Høgh, B., Jakobsen, P. H., Dziegiel, M. H., Borre, M., & Jepsen, S. (1990). Malariavacciner, en nødvendighed for fremtidig malariakontrol. Status og fremtidsudsigter. Ugeskrift for Laeger, 152(29), 2092-5.

Vancouver

Petersen E, Høgh B, Jakobsen PH, Dziegiel MH, Borre M, Jepsen S. Malariavacciner, en nødvendighed for fremtidig malariakontrol. Status og fremtidsudsigter. Ugeskrift for Laeger. 1990 Jul 16;152(29):2092-5.

Author

Petersen, E ; Høgh, B ; Jakobsen, P H ; Dziegiel, Morten Hanefeld ; Borre, M ; Jepsen, S. / Malariavacciner, en nødvendighed for fremtidig malariakontrol. Status og fremtidsudsigter. In: Ugeskrift for Laeger. 1990 ; Vol. 152, No. 29. pp. 2092-5.

Bibtex

@article{68af14f801604afaaa85f87936bd4a19,
title = "Malariavacciner, en n{\o}dvendighed for fremtidig malariakontrol. Status og fremtidsudsigter",
abstract = "Traditional malaria control is in a crisis on account of chemo-resistance of Plasmodium falciparum and insecticide-resistance of the malaria mosquito. New ways to control malaria have been opened by the possibility of producing a vaccine. Several malaria proteins (e.g. CSP, gp195, Pf155/RESA, GLURP) have been sequenced and it has been shown that most of the proteins have repetitive units. Analyses of T- and B-cell epitopes show that T-cell epitopes are mainly localized to the non-conserved parts of the antigens. Repeated malaria infections, therefore, may be seen as a number of primary infections, which partly explains the very slow development of immunity to the parasite. The initial three vaccination experiments in humans did not succeed in inducing a complete protection of the individual but it showed that partial immunization is possible.",
keywords = "Antigens, Protozoan, Humans, Malaria, Vaccines",
author = "E Petersen and B H{\o}gh and Jakobsen, {P H} and Dziegiel, {Morten Hanefeld} and M Borre and S Jepsen",
year = "1990",
month = jul,
day = "16",
language = "Dansk",
volume = "152",
pages = "2092--5",
journal = "Ugeskrift for Laeger",
issn = "0041-5782",
publisher = "Almindelige Danske Laegeforening",
number = "29",

}

RIS

TY - JOUR

T1 - Malariavacciner, en nødvendighed for fremtidig malariakontrol. Status og fremtidsudsigter

AU - Petersen, E

AU - Høgh, B

AU - Jakobsen, P H

AU - Dziegiel, Morten Hanefeld

AU - Borre, M

AU - Jepsen, S

PY - 1990/7/16

Y1 - 1990/7/16

N2 - Traditional malaria control is in a crisis on account of chemo-resistance of Plasmodium falciparum and insecticide-resistance of the malaria mosquito. New ways to control malaria have been opened by the possibility of producing a vaccine. Several malaria proteins (e.g. CSP, gp195, Pf155/RESA, GLURP) have been sequenced and it has been shown that most of the proteins have repetitive units. Analyses of T- and B-cell epitopes show that T-cell epitopes are mainly localized to the non-conserved parts of the antigens. Repeated malaria infections, therefore, may be seen as a number of primary infections, which partly explains the very slow development of immunity to the parasite. The initial three vaccination experiments in humans did not succeed in inducing a complete protection of the individual but it showed that partial immunization is possible.

AB - Traditional malaria control is in a crisis on account of chemo-resistance of Plasmodium falciparum and insecticide-resistance of the malaria mosquito. New ways to control malaria have been opened by the possibility of producing a vaccine. Several malaria proteins (e.g. CSP, gp195, Pf155/RESA, GLURP) have been sequenced and it has been shown that most of the proteins have repetitive units. Analyses of T- and B-cell epitopes show that T-cell epitopes are mainly localized to the non-conserved parts of the antigens. Repeated malaria infections, therefore, may be seen as a number of primary infections, which partly explains the very slow development of immunity to the parasite. The initial three vaccination experiments in humans did not succeed in inducing a complete protection of the individual but it showed that partial immunization is possible.

KW - Antigens, Protozoan

KW - Humans

KW - Malaria

KW - Vaccines

M3 - Tidsskriftartikel

C2 - 2205029

VL - 152

SP - 2092

EP - 2095

JO - Ugeskrift for Laeger

JF - Ugeskrift for Laeger

SN - 0041-5782

IS - 29

ER -

ID: 47557009