Osteoclasts prefer aged bone
Research output: Contribution to journal › Journal article › Research › peer-review
We investigated whether the age of the bones endogenously exerts control over the bone resorption ability of the osteoclasts, and found that osteoclasts preferentially develop and resorb bone on aged bone. These findings indicate that the bone matrix itself plays a role in targeted remodeling of aged bones.
| Original language | English |
|---|---|
| Journal | Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA |
| Volume | 18 |
| Issue number | 6 |
| Pages (from-to) | 751-9 |
| Number of pages | 9 |
| ISSN | 0937-941X |
| DOIs | |
| Publication status | Published - Jun 2007 |
- Acid Phosphatase, Aging, Animals, Bone Remodeling, Bone Resorption, Bone and Bones, Cattle, Cell Adhesion, Cell Differentiation, Cells, Cultured, Collagen Type I, Humans, Isoenzymes, Osteoclasts
Research areas
ID: 47556609