Quantitation of RHD by real-time polymerase chain reaction for determination of RHD zygosity and RHD mosaicism/chimerism: an evaluation of four quantitative methods
Research output: Contribution to journal › Journal article › Research › peer-review
Determination of RHD zygosity of the spouse is crucial in preconception counseling of families with history of hemolytic disease of the fetus and newborn caused by anti-D. RHD zygosity can be determined by quantitative real-time polymerase chain reaction (PCR) basically by determining RHD dosage, and this feature is relevant in investigating RHD mosaicism and chimerism.
Original language | English |
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Journal | Transfusion |
Volume | 47 |
Issue number | 4 |
Pages (from-to) | 715-22 |
Number of pages | 8 |
ISSN | 0041-1132 |
DOIs | |
Publication status | Published - Apr 2007 |
- Aged, 80 and over, Chimerism, Genotype, Heterozygote, Homozygote, Humans, Male, Mosaicism, Polymerase Chain Reaction, Polymorphism, Restriction Fragment Length, Reproducibility of Results, Rh-Hr Blood-Group System
Research areas
ID: 47555779