Quantitation of RHD by real-time polymerase chain reaction for determination of RHD zygosity and RHD mosaicism/chimerism: an evaluation of four quantitative methods

Research output: Contribution to journalJournal articleResearchpeer-review

Determination of RHD zygosity of the spouse is crucial in preconception counseling of families with history of hemolytic disease of the fetus and newborn caused by anti-D. RHD zygosity can be determined by quantitative real-time polymerase chain reaction (PCR) basically by determining RHD dosage, and this feature is relevant in investigating RHD mosaicism and chimerism.
Original languageEnglish
JournalTransfusion
Volume47
Issue number4
Pages (from-to)715-22
Number of pages8
ISSN0041-1132
DOIs
Publication statusPublished - Apr 2007

    Research areas

  • Aged, 80 and over, Chimerism, Genotype, Heterozygote, Homozygote, Humans, Male, Mosaicism, Polymerase Chain Reaction, Polymorphism, Restriction Fragment Length, Reproducibility of Results, Rh-Hr Blood-Group System

ID: 47555779