Serum levels of ficolin-3 (Hakata antigen) in patients with systemic lupus erythematosus

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Serum levels of ficolin-3 (Hakata antigen) in patients with systemic lupus erythematosus. / Andersen, T.; Munthe-Fog, L.; Garred, P.; Jacobsen, Søren; Andersen, Trine; Munthe-Fog, Lea; Garred, Peter; Jacobsen, Søren.

In: Journal of Rheumatology, Vol. 36, No. 4, 01.04.2009, p. 757-9.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Andersen, T, Munthe-Fog, L, Garred, P, Jacobsen, S, Andersen, T, Munthe-Fog, L, Garred, P & Jacobsen, S 2009, 'Serum levels of ficolin-3 (Hakata antigen) in patients with systemic lupus erythematosus', Journal of Rheumatology, vol. 36, no. 4, pp. 757-9. https://doi.org/10.3899/jrheum.080361, https://doi.org/10.3899/jrheum.080361

APA

Andersen, T., Munthe-Fog, L., Garred, P., Jacobsen, S., Andersen, T., Munthe-Fog, L., Garred, P., & Jacobsen, S. (2009). Serum levels of ficolin-3 (Hakata antigen) in patients with systemic lupus erythematosus. Journal of Rheumatology, 36(4), 757-9. https://doi.org/10.3899/jrheum.080361, https://doi.org/10.3899/jrheum.080361

Vancouver

Andersen T, Munthe-Fog L, Garred P, Jacobsen S, Andersen T, Munthe-Fog L et al. Serum levels of ficolin-3 (Hakata antigen) in patients with systemic lupus erythematosus. Journal of Rheumatology. 2009 Apr 1;36(4):757-9. https://doi.org/10.3899/jrheum.080361, https://doi.org/10.3899/jrheum.080361

Author

Andersen, T. ; Munthe-Fog, L. ; Garred, P. ; Jacobsen, Søren ; Andersen, Trine ; Munthe-Fog, Lea ; Garred, Peter ; Jacobsen, Søren. / Serum levels of ficolin-3 (Hakata antigen) in patients with systemic lupus erythematosus. In: Journal of Rheumatology. 2009 ; Vol. 36, No. 4. pp. 757-9.

Bibtex

@article{675acd40537411df928f000ea68e967b,
title = "Serum levels of ficolin-3 (Hakata antigen) in patients with systemic lupus erythematosus",
abstract = "OBJECTIVE: Ficolin-3 is a serum protein of putative importance in autoimmunity. Our objective was to investigate any differential expression of ficolin-3 in patients with systemic lupus erythematosus (SLE) or its clinical subsets. METHODS: Serum levels of ficolin-3 (S-ficolin-3) were determined in 95 patients with SLE and 103 healthy controls using an ELISA. RESULTS: Median S-ficolin-3 was 56.1 microg/ml (range 0 to >or=87.3) and 32.4 microg/ml (10 to >or=87.3) in patients and controls, respectively (p<0.001). Increased S-ficolin-3 was associated with hemolysis, positive Coombs test, and lymphopenia, but not with SLE Disease Activity Index scores or C-reactive protein. In one patient without detectable S-ficolin-3, the FCN3 gene appeared normal. CONCLUSION: The elevation of S-ficolin-3 and its association with specific manifestations in SLE may indicate a pathogenetic role of ficolin-3 in SLE.",
author = "T. Andersen and L. Munthe-Fog and P. Garred and S{\o}ren Jacobsen and Trine Andersen and Lea Munthe-Fog and Peter Garred and S{\o}ren Jacobsen",
note = "Keywords: Adolescent; Adult; Aged; Child; Female; Glycoproteins; Humans; Lectins; Lupus Erythematosus, Systemic; Male; Middle Aged; Severity of Illness Index; Young Adult",
year = "2009",
month = apr,
day = "1",
doi = "10.3899/jrheum.080361",
language = "English",
volume = "36",
pages = "757--9",
journal = "Journal of Rheumatology",
issn = "0315-162X",
publisher = "Journal of Rheumatology Publishing Co. Ltd.",
number = "4",

}

RIS

TY - JOUR

T1 - Serum levels of ficolin-3 (Hakata antigen) in patients with systemic lupus erythematosus

AU - Andersen, T.

AU - Munthe-Fog, L.

AU - Garred, P.

AU - Jacobsen, Søren

AU - Andersen, Trine

AU - Munthe-Fog, Lea

AU - Garred, Peter

AU - Jacobsen, Søren

N1 - Keywords: Adolescent; Adult; Aged; Child; Female; Glycoproteins; Humans; Lectins; Lupus Erythematosus, Systemic; Male; Middle Aged; Severity of Illness Index; Young Adult

PY - 2009/4/1

Y1 - 2009/4/1

N2 - OBJECTIVE: Ficolin-3 is a serum protein of putative importance in autoimmunity. Our objective was to investigate any differential expression of ficolin-3 in patients with systemic lupus erythematosus (SLE) or its clinical subsets. METHODS: Serum levels of ficolin-3 (S-ficolin-3) were determined in 95 patients with SLE and 103 healthy controls using an ELISA. RESULTS: Median S-ficolin-3 was 56.1 microg/ml (range 0 to >or=87.3) and 32.4 microg/ml (10 to >or=87.3) in patients and controls, respectively (p<0.001). Increased S-ficolin-3 was associated with hemolysis, positive Coombs test, and lymphopenia, but not with SLE Disease Activity Index scores or C-reactive protein. In one patient without detectable S-ficolin-3, the FCN3 gene appeared normal. CONCLUSION: The elevation of S-ficolin-3 and its association with specific manifestations in SLE may indicate a pathogenetic role of ficolin-3 in SLE.

AB - OBJECTIVE: Ficolin-3 is a serum protein of putative importance in autoimmunity. Our objective was to investigate any differential expression of ficolin-3 in patients with systemic lupus erythematosus (SLE) or its clinical subsets. METHODS: Serum levels of ficolin-3 (S-ficolin-3) were determined in 95 patients with SLE and 103 healthy controls using an ELISA. RESULTS: Median S-ficolin-3 was 56.1 microg/ml (range 0 to >or=87.3) and 32.4 microg/ml (10 to >or=87.3) in patients and controls, respectively (p<0.001). Increased S-ficolin-3 was associated with hemolysis, positive Coombs test, and lymphopenia, but not with SLE Disease Activity Index scores or C-reactive protein. In one patient without detectable S-ficolin-3, the FCN3 gene appeared normal. CONCLUSION: The elevation of S-ficolin-3 and its association with specific manifestations in SLE may indicate a pathogenetic role of ficolin-3 in SLE.

U2 - 10.3899/jrheum.080361

DO - 10.3899/jrheum.080361

M3 - Journal article

C2 - 19208603

VL - 36

SP - 757

EP - 759

JO - Journal of Rheumatology

JF - Journal of Rheumatology

SN - 0315-162X

IS - 4

ER -

ID: 19440313