The lectin pathway of complement: Advantage or disadvantage in HIV pathogenesis?

Research output: Contribution to journal › Review › Research › peer-review

Standard

The lectin pathway of complement : Advantage or disadvantage in HIV pathogenesis? / Ballegaard, Vibe Cecilie Diederich; Haugaard, Anna Karen; Garred, P; Nielsen, Susanne Dam; Munthe-Fog, L.

In: Clinical Immunology, Vol. 154, No. 1, 09.2014, p. 13-25.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Ballegaard, VCD, Haugaard, AK, Garred, P, Nielsen, SD & Munthe-Fog, L 2014, 'The lectin pathway of complement: Advantage or disadvantage in HIV pathogenesis?', Clinical Immunology, vol. 154, no. 1, pp. 13-25. https://doi.org/10.1016/j.clim.2014.06.002

APA

Ballegaard, V. C. D., Haugaard, A. K., Garred, P., Nielsen, S. D., & Munthe-Fog, L. (2014). The lectin pathway of complement: Advantage or disadvantage in HIV pathogenesis? Clinical Immunology, 154(1), 13-25. https://doi.org/10.1016/j.clim.2014.06.002

Vancouver

Ballegaard VCD, Haugaard AK, Garred P, Nielsen SD, Munthe-Fog L. The lectin pathway of complement: Advantage or disadvantage in HIV pathogenesis? Clinical Immunology. 2014 Sep;154(1):13-25. https://doi.org/10.1016/j.clim.2014.06.002

Author

Ballegaard, Vibe Cecilie Diederich ; Haugaard, Anna Karen ; Garred, P ; Nielsen, Susanne Dam ; Munthe-Fog, L. / The lectin pathway of complement : Advantage or disadvantage in HIV pathogenesis?. In: Clinical Immunology. 2014 ; Vol. 154, No. 1. pp. 13-25.

Bibtex

@article{20fbcd17af9f4b469a3cc1510532008f,
title = "The lectin pathway of complement: Advantage or disadvantage in HIV pathogenesis?",
abstract = "The pattern recognition molecules of the lectin complement pathway are important components of the innate immune system with known functions in host-virus interactions. This paper summarizes current knowledge of how these intriguing molecules, including mannose-binding lectin (MBL), Ficolin-1, -2 and -3, and collectin-11 (CL-11) may influence HIV-pathogenesis. It has been demonstrated that MBL is capable of binding and neutralizing HIV and may affect host susceptibility to HIV infection and disease progression. In addition, MBL may cause variations in the host immune response against HIV. Ficolin-1, -2 and -3 and CL-11 could have similar functions in HIV infection as the ficolins have been shown to play a role in other viral infections, and CL-11 resembles MBL and the ficolins in structure and binding capacity.",
keywords = "Complement Pathway, Mannose-Binding Lectin, HIV Infections, Humans, Models, Biological, Polymorphism, Genetic",
author = "Ballegaard, {Vibe Cecilie Diederich} and Haugaard, {Anna Karen} and P Garred and Nielsen, {Susanne Dam} and L Munthe-Fog",
note = "Copyright {\textcopyright} 2014 Elsevier Inc. All rights reserved.",
year = "2014",
month = sep,
doi = "10.1016/j.clim.2014.06.002",
language = "English",
volume = "154",
pages = "13--25",
journal = "Clinical Immunology",
issn = "1521-6616",
publisher = "Academic Press",
number = "1",

}

RIS

TY - JOUR

T1 - The lectin pathway of complement

T2 - Advantage or disadvantage in HIV pathogenesis?

AU - Ballegaard, Vibe Cecilie Diederich

AU - Haugaard, Anna Karen

AU - Garred, P

AU - Nielsen, Susanne Dam

AU - Munthe-Fog, L

N1 - Copyright © 2014 Elsevier Inc. All rights reserved.

PY - 2014/9

Y1 - 2014/9

N2 - The pattern recognition molecules of the lectin complement pathway are important components of the innate immune system with known functions in host-virus interactions. This paper summarizes current knowledge of how these intriguing molecules, including mannose-binding lectin (MBL), Ficolin-1, -2 and -3, and collectin-11 (CL-11) may influence HIV-pathogenesis. It has been demonstrated that MBL is capable of binding and neutralizing HIV and may affect host susceptibility to HIV infection and disease progression. In addition, MBL may cause variations in the host immune response against HIV. Ficolin-1, -2 and -3 and CL-11 could have similar functions in HIV infection as the ficolins have been shown to play a role in other viral infections, and CL-11 resembles MBL and the ficolins in structure and binding capacity.

AB - The pattern recognition molecules of the lectin complement pathway are important components of the innate immune system with known functions in host-virus interactions. This paper summarizes current knowledge of how these intriguing molecules, including mannose-binding lectin (MBL), Ficolin-1, -2 and -3, and collectin-11 (CL-11) may influence HIV-pathogenesis. It has been demonstrated that MBL is capable of binding and neutralizing HIV and may affect host susceptibility to HIV infection and disease progression. In addition, MBL may cause variations in the host immune response against HIV. Ficolin-1, -2 and -3 and CL-11 could have similar functions in HIV infection as the ficolins have been shown to play a role in other viral infections, and CL-11 resembles MBL and the ficolins in structure and binding capacity.

KW - Complement Pathway, Mannose-Binding Lectin

KW - HIV Infections

KW - Humans

KW - Models, Biological

KW - Polymorphism, Genetic

U2 - 10.1016/j.clim.2014.06.002

DO - 10.1016/j.clim.2014.06.002

M3 - Review

C2 - 24928325

VL - 154

SP - 13

EP - 25

JO - Clinical Immunology

JF - Clinical Immunology

SN - 1521-6616

IS - 1

ER -

ID: 138216380