Tuberculosis-Related Diabetes: Is It Reversible after Complete Treatment?
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Tuberculosis-Related Diabetes : Is It Reversible after Complete Treatment? / Aftab, Huma; Christensen, Dirk L.; Ambreen, Atiqa; Jamil, Mohammad; Garred, Peter; Petersen, Jørgen H.; Nielsen, Susanne D.; Bygbjerg, Ib C.
In: American Journal of Tropical Medicine and Hygiene, Vol. 97, No. 4, 10.2017, p. 1099-1102.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Tuberculosis-Related Diabetes
T2 - Is It Reversible after Complete Treatment?
AU - Aftab, Huma
AU - Christensen, Dirk L.
AU - Ambreen, Atiqa
AU - Jamil, Mohammad
AU - Garred, Peter
AU - Petersen, Jørgen H.
AU - Nielsen, Susanne D.
AU - Bygbjerg, Ib C.
PY - 2017/10
Y1 - 2017/10
N2 - Individuals with newly diagnosed tuberculosis (TB) were screened for diabetes (DM) with fasting plasma glucose (FPG) in Pakistan. A significant decrease in FPG was observed when TB was treated. Of those with newly diagnosed DM, 46% and 62% no longer had hyperglycemia after 3 and 6 months, respectively. Individuals with known DM also showed a significant decrease in fasting plasma levels when treated for TB, but after 3 months none had normoglycemia, and after 6 months 9.2% were normoglycemic. Thus, TB-related DM may abate when the stress terminates, as is the case in gestational DM. However, because stress hyperglycemia may be associated with subsequent risk of developing DM, follow-up is recommended.
AB - Individuals with newly diagnosed tuberculosis (TB) were screened for diabetes (DM) with fasting plasma glucose (FPG) in Pakistan. A significant decrease in FPG was observed when TB was treated. Of those with newly diagnosed DM, 46% and 62% no longer had hyperglycemia after 3 and 6 months, respectively. Individuals with known DM also showed a significant decrease in fasting plasma levels when treated for TB, but after 3 months none had normoglycemia, and after 6 months 9.2% were normoglycemic. Thus, TB-related DM may abate when the stress terminates, as is the case in gestational DM. However, because stress hyperglycemia may be associated with subsequent risk of developing DM, follow-up is recommended.
KW - Adult
KW - Aged
KW - Aged, 80 and over
KW - Antitubercular Agents
KW - Diabetes Mellitus
KW - Female
KW - Humans
KW - Hypoglycemic Agents
KW - Male
KW - Middle Aged
KW - Pakistan
KW - Prevalence
KW - Tuberculosis
KW - Journal Article
U2 - 10.4269/ajtmh.16-0816
DO - 10.4269/ajtmh.16-0816
M3 - Journal article
C2 - 28820679
VL - 97
SP - 1099
EP - 1102
JO - Journal. National Malaria Society
JF - Journal. National Malaria Society
SN - 0002-9637
IS - 4
ER -
ID: 185403262