Inge Marie Svane
Clinical Professor
- 2019
- Published
Assessment of extracellular matrix and tissue derived metabolites in a liquid biopsy for identifying endotypes of metastatic melanoma patients with differential response to immune checkpoint inhibitor treatment.
Willumsen, N., Bager, C. L., Jensen, C., Karsdal, M. A., Madsen, Daniel Hargbøl, Hansen, M., Schmidt, H. & Svane, Inge Marie, 2019, In: Journal of Clinical Oncology. 37, 15_suppl, e14050.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
B-cell frequencies and immunoregulatory phenotypes in myeloproliferative neoplasms: influence of ruxolitinib, interferon-α2, or combination treatment
Sørensen, A. L., Bjørn, M. E., Riley, C. H., Holmstrøm, M., Andersen, Mads Hald, Svane, Inge Marie, Mikkelsen, S. U., Skov, V., Kjær, L., Hasselbalch, H. C. & Nielsen, C. H., 2019, In: European Journal of Haematology. 103, 4, p. 351-361 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cancerimmunterapi til behandling af hæmatologisk cancer
Holmström, M. O., Klausen, U., Jørgensen, N. G., Holmberg, S., Grauslund, J., Met, Ö., Svane, Inge Marie, Pedersen, Lars Møller, Knudsen, L. M., Hasselbalch, Hans Carl & Andersen, Mads Hald, 2019, In: Ugeskrift for Laeger. 181, 10, 5 p., V06180421.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chimeric antigen receptor-T-cellebehandling
Muller, Klaus, Ifversen, M., Kielsen, K., Petersen, S. L., Met, Ö. & Svane, Inge Marie, 2019, In: Ugeskrift for Laeger. 181, 20A, 5 p., V05190309.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Collagen density regulates the activity of tumor-infiltrating T cells
Kuczek, D. E., Larsen, A. M. H., Thorseth, M., Carretta, M., Kalvisa, A., Siersbæk, M. S., Simões, A. M. C., Roslind, A., Engelholm, Lars Henning, Noessner, E., dqp123, dqp123, Svane, Inge Marie, Straten, P. T., Grøntved, L. & Madsen, D. H., 2019, In: Journal for ImmunoTherapy of Cancer. 7, 1, 15 p., 68.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dabrafenib, trametinib and pembrolizumab or placebo in BRAF-mutant melanoma
Ascierto, P. A., Ferrucci, P. F., Fisher, R., Del Vecchio, M., Atkinson, V., Schmidt, H., Schachter, J., Queirolo, P., Long, G. V., Di Giacomo, A. M., Svane, Inge Marie, Lotem, M., Bar-Sela, G., Couture, F., Mookerjee, B., Ghori, R., Ibrahim, N., Moreno, B. H. & Ribas, A., 2019, In: Nature Medicine. 25, 6, p. 941-946 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential effects of corticosteroids and anti-TNF on tumor-specific immune responses: implications for the management of irAEs
Draghi, A., Borch, T. H., Radic, H. D., Chamberlain, C. A., Gokuldass, A., Svane, Inge Marie & dqp123, dqp123, 2019, In: International Journal of Cancer. 145, 5, p. 1408-1413 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discontinuation of anti-PD-1 antibody therapy in the absence of disease progression or treatment limiting toxicity: clinical outcomes in advanced melanoma
Jansen, Y. J. L., Rozeman, E. A., Mason, R., Goldinger, S. M., Geukes Foppen, M. H., Højberg, L., Schmidt, H., van Thienen, J. V., Haanen, J. B. A. G., Tiainen, L., Svane, I. M., Mäkelä, S., Seremet, T., Arance, A., Dummer, R., Bastholt, L., Nyakas, M., Straume, O., Menzies, A. M., Long, G. V. & 3 others, , 2019, In: Annals of Oncology. 30, 7, p. 1154-1161 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficacy of adoptive therapy with tumor-infiltrating lymphocytes and recombinant interleukin-2 in advanced cutaneous melanoma: a systematic review and meta-analysis
Dafni, U., Michielin, O., Lluesma, S. M., Tsourti, Z., Polydoropoulou, V., Karlis, D., Besser, M. J., Haanen, J., Svane, Inge Marie, Ohashi, P. S., Kammula, U. S., Orcurto, A., Zimmermann, S., Trueb, L., Klebanoff, C. A., Lotze, M. T., Kandalaft, L. E. & Coukos, G., 2019, In: Annals of Oncology. 30, 12, p. 1902-1913 12 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Empty peptide-receptive MHC class I molecules for efficient detection of antigen-specific T cells
Saini, S. K., Tamhane, T., Anjanappa, R., Saikia, A., Ramskov, S., dqp123, dqp123, Svane, Inge Marie, Jakobsen, S. N., Garcia-Alai, M., Zacharias, M., Meijers, R., Springer, S. & Hadrup, S. R., 2019, In: Science immunology. 4, 37, eaau9039.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of Two Dosing Regimens for Nivolumab in Combination With Ipilimumab in Patients With Advanced Melanoma: Results From the Phase IIIb/IV CheckMate 511 Trial
Lebbé, C., Meyer, N., Mortier, L., Marquez-Rodas, I., Robert, C., Rutkowski, P., Menzies, A. M., Eigentler, T., Ascierto, P. A., Smylie, M., Schadendorf, D., Ajaz, M., Svane, Inge Marie, Gonzalez, R., Rollin, L., Lord-Bessen, J., Saci, A., Grigoryeva, E. & Pigozzo, J., 2019, In: Journal of Clinical Oncology. 37, 11, p. 867-875Research output: Contribution to journal › Journal article › Research › peer-review
- Published
HER2 CAR-T cells eradicate uveal melanoma and T-cell therapy–resistant human melanoma in IL2 transgenic NOD/SCID IL2 receptor knockout mice
Forsberg, E. M. V., Lindberg, M. F., Jespersen, H., Alsen, S., Bagge, R. O., dqp123, dqp123, Svane, Inge Marie, Nilsson, O., Ny, L., Nilsson, L. M. & Nilsson, J. A., 2019, In: Cancer Research. 79, 5, p. 899-904 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High frequencies of circulating memory T cells specific for calreticulin exon 9 mutations in healthy individuals
Holmström, M. O., Ahmad, S. M., Klausen, U., Bendtsen, S. K., Martinenaite, E., Riley, C. H., Svane, Inge Marie, Kjær, L., Skov, V., Ellervik, Christina, Pallisgaard, N., Hasselbalch, H. C. & Andersen, Mads Hald, 2019, In: Blood Cancer Journal. 9, 2, 8.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immunoprofiles of colorectal cancer from Lynch syndrome
Walkowska, J., Kallemose, T., Jönsson, G., Jönsson, M., Andersen, Ove, Andersen, Mads Hald, Svane, Inge Marie, Langkilde, A., Nilbert, Mef Christina & Therkildsen, C., 2019, In: OncoImmunology. 8, 1, 9 p., e1515612.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immunterapi til patienter med malignt melanom og hjernemetastaser
Simonsen, L. T., Schmidt, A. M. S., Øllegaard, T. H., Svane, Inge Marie, Bastholt, L., Luczak, A. A. & Schmidt, H., 2019, In: Ugeskrift for Laeger. 181, 24, 5 p., V01190057.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long-Term Exposure to Inflammation Induces Differential Cytokine Patterns and Apoptosis in Dendritic Cells
Carstensen, L. S., Lie-Andersen, O., Obers, A., Crowther, M. D., Svane, Inge Marie & Hansen, M., 2019, In: Frontiers in Immunology. 10, 11 p., 2702.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MERTK Acts as a costimulatory receptor on human cd8 t cells
Peeters, M. J. W., Dulkeviciute, D., Draghi, A., Ritter, C., Rahbech, A., Skadborg, S. K., Seremet, T., Simoes, A. M. C., Martinenaite, E., Halldorsdottir, H. R., Andersen, Mads Hald, Olofsson, G. H., Svane, Inge Marie, Rasmussen, Lene Juel, Met, Özcan, Becker, J. C., dqp123, dqp123, Desler, Claus & Straten, P. T., 2019, In: Cancer Immunology Research. 7, 9, p. 1472-1484 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peptide Super-Agonist Enhances T-Cell Responses to Melanoma
Galloway, S. A. E., Dolton, G., Attaf, M., Wall, A., Fuller, A., Rius, C., Bianchi, V., Theaker, S., Lloyd, A., Caillaud, M. E., Svane, Inge Marie, dqp123, dqp123, Cole, D. K., Szomolay, B., Rizkallah, P. & Sewell, A. K., 2019, In: Frontiers in Immunology. 10, 18 p., 319.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peripheral memory T cells specific for Arginase-1
Martinenaite, E., Ahmad, S. M., Svane, Inge Marie & Andersen, Mads Hald, 2019, In: Cellular and Molecular Immunology. 16, 8, p. 718-719 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Real-World Impact of Immune Checkpoint Inhibitors in Metastatic Uveal Melanoma
Bol, K. F., Ellebaek, E., Hoejberg, L., Bagger, M. M., Larsen, M. S., Klausen, T. W., Køhler, U. H., Schmidt, H., Bastholt, L., Kiilgaard, Jens Folke, dqp123, dqp123 & Svane, Inge Marie, 2019, In: Cancers. 11, 10, 11 p., 1489;.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Real-world evidence to guide healthcare policies in oncology
dqp123, dqp123, Hansen, S. W. & Svane, Inge Marie, 2019, In: OncoTarget. 10, 44, p. 4513-4515Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Survival Outcomes in Patients With Previously Untreated BRAF Wild-Type Advanced Melanoma Treated With Nivolumab Therapy: Three-Year Follow-up of a Randomized Phase 3 Trial
Ascierto, P. A., Long, G. V., Robert, C., Brady, B., Dutriaux, C., Di Giacomo, A. M., Mortier, L., Hassel, J. C., Rutkowski, P., McNeil, C., Kalinka-Warzocha, E., Savage, K. J., Hernberg, M. M., Lebbé, C., Charles, J., Mihalcioiu, C., Chiarion-Sileni, V., Mauch, C., Cognetti, F., Ny, L. & 8 others, , 2019, In: JAMA Oncology. 5, 2, p. 187-194Research output: Contribution to journal › Journal article › Research › peer-review
- Published
T cell recognition of novel shared breast cancer antigens is frequently observed in peripheral blood of breast cancer patients
Viborg, N., Ramskov, S., Andersen, R. S., Sturm, T., Fugmann, T., Bentzen, A. K., Rafa, V. M., Straten, P. T., Svane, Inge Marie, Met, Özcan & Hadrup, S. R., 2019, In: OncoImmunology. 8, 12, 11 p., 1663107.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The real-world impact of modern treatments on the survival of patients with metastatic melanoma
dqp123, dqp123, Ellebaek, E., Øllegaard, T. H., Duval, L., Aaby, J. B., Hoejberg, L., Køhler, U. H., Schmidt, H., Bastholt, L. & Svane, Inge Marie, 2019, In: European Journal of Cancer. 108, p. 25-32 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tumour-reactive T cell subsets in the microenvironment of ovarian cancer
Westergaard, M. C. W., Andersen, R., Chong, C., Kjeldsen, J. W., Pedersen, M., Friese, C., Hasselager, T., Lajer, H., Coukos, G., Bassani-Sternberg, M., dqp123, dqp123 & Svane, Inge Marie, 2019, In: British Journal of Cancer. 120, p. 424-434Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Sorted peripheral blood cells identify CALR mutations in B- and T-lymphocytes
Kjaer, L., Holmström, M. O., Cordua, S., Andersen, Mads Hald, Svane, Inge Marie, Thomassen, M., Kruse, T. A., Pallisgaard, N., Skov, V. & Hasselbalch, Hans Carl, Apr 2018, In: Leukemia and Lymphoma. 59, 4, p. 973-977 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The calreticulin (CALR) exon 9 mutations are promising targets for cancer immune therapy
Holmstrom, M. O., Martinenaite, E., Ahmad, S. M., Met, Özcan, Friese, C., Kjaer, L., Riley, C. H., Straten, P. T., Svane, Inge Marie, Hasselbalch, Hans Carl & Andersen, Mads Hald, 1 Feb 2018, In: Leukemia. 32, 2, p. 429-437Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adoptive cell therapy with tumor-infiltrating lymphocytes in patients with metastatic ovarian cancer: a pilot study
Pedersen, M., Westergaard, M. C. W., Milne, K., Nielsen, M., Borch, T. H., Poulsen, L. G., Hendel, Helle Westergren, Kennedy, M., Briggs, G., Ledoux, S., Nøttrup, T. J., Andersen, P., Hasselager, T., Met, Ö., Nelson, B. H., dqp123, dqp123 & Svane, Inge Marie, 2018, In: OncoImmunology. 7, 12, 12 p., e1502905.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cancer immunotherapy in patients with brain metastases
Caponnetto, S., Draghi, A., Borch, T. H., Nuti, M., Cortesi, E., Svane, Inge Marie & dqp123, dqp123, 2018, In: Cancer Immunology, Immunotherapy. 67, 5, p. 703-711 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Cancerimmunterapi
Kjeldsen, J. W., dqp123, dqp123 & Svane, Inge Marie, 2018, In: Ugeskrift for Laeger. 180, 5 p., V09170691.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Checkpoint inhibitors in breast cancer - current status
Polk, A., Svane, Inge Marie, Andersson, M. & Nielsen, Dorte Lisbet, 2018, In: Cancer Treatment Reviews. 63, p. 122-134Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of anti-drug antibodies is associated with shortened survival in patients with metastatic melanoma treated with ipilimumab
Kverneland, A. H., Enevold, C., dqp123, dqp123, Bastholt, L., Svane, Inge Marie & Nielsen, C. H., 2018, In: OncoImmunology. 7, 5, p. e1424674 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Durable clinical responses and long-term follow-up of stage III-IV non-small-cell lung cancer (NSCLC) patients treated with IDO peptide vaccine in a phase i study-a brief research report
Kjeldsen, J. W., Iversen, T. Z., Engell-Noerregaard, L., Mellemgaard, A., Andersen, Mads Hald & Svane, Inge Marie, 2018, In: Frontiers in Immunology. 9, SEP, 6 p., 2145.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Frequent adaptive immune responses against arginase-1
Martinenaite, E., Mortensen, R. E. J., Hansen, M., Orebo Holmström, M., Munir Ahmad, S., Grønne Dahlager Jørgensen, N., Met, Özcan, dqp123, dqp123, Svane, Inge Marie & Andersen, Mads Hald, 2018, In: OncoImmunology. 7, 3, 9 p., e1404215.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Non-invasive biomarkers derived from the extracellular matrix associate with response to immune checkpoint blockade (anti-CTLA-4) in metastatic melanoma patients
Jensen, C., Madsen, D. H., Hansen, M., Schmidt, H., Svane, Inge Marie, Karsdal, M. A. & Willumsen, N., 2018, In: Journal for ImmunoTherapy of Cancer. 6, 1, p. 1-10 10 p., 152.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel Strategies for Peptide-Based Vaccines in Hematological Malignancies
Klausen, U., Holmberg, S., Holmstrom, M. O., Jorgensen, N. G. D., Grauslund, J. H., Svane, Inge Marie & Andersen, Mads Hald, 2018, In: Frontiers in Immunology. 9, 8 p., 2264.Research output: Contribution to journal › Review › Research › peer-review
- Published
Peptide-MHC Class I Tetramers Can Fail To Detect Relevant Functional T Cell Clonotypes and Underestimate Antigen-Reactive T Cell Populations
Rius, C., Attaf, M., Tungatt, K., Bianchi, V., Legut, M., Bovay, A., dqp123, dqp123, Thor Straten, P., Peakman, M., Svane, Inge Marie, Ott, S., Connor, T., Szomolay, B., Dolton, G. & Sewell, A. K., 2018, In: The Journal of Immunology. 200, 7, p. 2263-2279Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spontaneous T-cell responses against the immune check point programmed-death-ligand 1 (PD-L1) in patients with chronic myeloproliferative neoplasms correlate with disease stage and clinical response
Holmström, M. O., Riley, C. H., Skov, V., Svane, Inge Marie, Hasselbalch, Hans Carl & Andersen, Mads Hald, 2018, In: OncoImmunology. 7, 6, e1433521.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
T cells isolated from patients with checkpoint inhibitor-resistant melanoma are functional and can mediate tumor regression
Andersen, R., Borch, T. H., Draghi, A., Gokuldass, A., Rana, M. A. H., Pedersen, M., Nielsen, M., Kongsted, P., Kjeldsen, J. W., Westergaard, M. C. W., Radic, H. D., Chamberlain, C. A., Hølmich, Lisbet Rosenkrantz, Hendel, Helle Westergren, Larsen, M. S., Met, Özcan, Svane, Inge Marie & dqp123, dqp123, 2018, In: Annals of Oncology. 29, 7, p. 1575-1581 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
T-cell Responses in the Microenvironment of Primary Renal Cell Carcinoma-Implications for Adoptive Cell Therapy
Andersen, R., Westergaard, M. C. W., Kjeldsen, J. W., Müller, A., Pedersen, N. W., Hadrup, S. R., Met, Özcan, Seliger, B., Kromann-Andersen, B., Hasselager, T., dqp123, dqp123 & Svane, Inge Marie, 2018, In: Cancer Immunology Research. 6, 2, p. 222-235 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The inhibitory checkpoint, PD-L2, is a target for effector T cells: Novel possibilities for immune therapy
Ahmad, S. M., Martinenaite, E., Holmström, M., Jørgensen, M. A., Met, Özcan, Nastasi, C., Klausen, U., dqp123, dqp123, Pedersen, Lars Møller, Munksgaard, Lars, Ødum, Niels, Woetmann, Anders , Svane, Inge Marie & Andersen, Mads Hald, 2018, In: OncoImmunology. 7, 2, 10 p., e1390641.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Acquired Immune Resistance Follows Complete Tumor Regression without Loss of Target Antigens or IFNγ Signaling
Donia, M., Harbst, K., van Buuren, M., Kvistborg, P., Lindberg, M. F., Andersen, R., Idorn, M., Munir Ahmad, S., Ellebæk, E., Mueller, A., Fagone, P., Nicoletti, F., Libra, M., Lauss, M., Hadrup, S. R., Schmidt, H., Andersen, M. H., Thor Straten, P., Nilsson, J. A., Schumacher, T. N. & 3 others, , 1 Sep 2017, In: Cancer Research. 77, 17, p. 4562-4566 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ipilimumab 10 mg/kg versus ipilimumab 3 mg/kg in patients with unresectable or metastatic melanoma: a randomised, double-blind, multicentre, phase 3 trial
Ascierto, P. A., Del Vecchio, M., Robert, C., Mackiewicz, A., Chiarion-Sileni, V., Arance, A., Lebbé, C., Bastholt, L., Hamid, O., Rutkowski, P., McNeil, C., Garbe, C., Loquai, C., Dreno, B., Thomas, L., Grob, J-J., Liszkay, G., Nyakas, M., Gutzmer, R., Pikiel, J. & 10 others, , May 2017, In: Lancet Oncology. 18, 5, p. 611-622 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dendritic cell vaccination in combination with docetaxel for patients with metastatic castration-resistant prostate cancer: A randomized phase II study
Kongsted, P., Borch, T. H., Ellebaek, E., Iversen, T. Z., Andersen, R., Met, Özcan, Hansen, M., Lindberg, H., Sengeløv, L. & Svane, Inge Marie, 1 Apr 2017, In: Cytotherapy. 19, 4, p. 500-513 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cancer immunotherapy in patients with preexisting autoimmune disorders
dqp123, dqp123, Pedersen, M. & Svane, Inge Marie, Apr 2017, In: Seminars in Immunopathology. 39, 3, p. 333-337 5 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Clinical Impact of the Number of Treatment Cycles in First-Line Docetaxel for Patients With Metastatic Castration-Resistant Prostate Cancer
Kongsted, P., Svane, Inge Marie, Lindberg, H. & Sengeløv, L., Apr 2017, In: Clinical Genitourinary Cancer. 15, 2, p. e281-e287Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clinical responses to adoptive T-cell transfer can be modeled in an autologous immune-humanized mouse model
Jespersen, H., Lindberg, M. F., dqp123, dqp123, Söderberg, E. M. V., Andersen, R., Keller, U., Ny, L., Svane, Inge Marie, Nilsson, L. M. & Nilsson, J. A., 2017, In: Nature Communications. 8, 10 p., 707.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immunterapi er kræftbehandling med en helt ny bivirkningsprofil
Kondrup, M., Raunkilde, L., Svane, Inge Marie, Schmidt, H. & Bastholt, L., 2017, In: Ugeskrift for Laeger. 179, 5 p., V05170365.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Indoleamine 2,3-dioxygenase and survivin peptide vaccine combined with temozolomide in metastatic melanoma
Nitschke, N. J., Bjoern, J., Iversen, T. Z., Andersen, Mads Hald & Svane, Inge Marie, 2017, In: Stem Cell Investigation. 4, 13 p., 77.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of ipilimumab on expanded tumour derived T cells from patients with metastatic melanoma
Bjoern, J., Lyngaa, R., Andersen, R., Hølmich, Lisbet Rosenkrantz, Hadrup, S. R., dqp123, dqp123 & Svane, Inge Marie, 2017, In: OncoTarget. 8, 16, p. 27062-27074Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma
Lauss, M., dqp123, dqp123, Harbst, K., Andersen, R., Mitra, S., Rosengren, F., Salim, M., Vallon-Christersson, J., Törngren, T., Kvist, A., Ringnér, M., Svane, Inge Marie & Jönsson, G., 2017, In: Nature Communications. 8, 11 p., 1738.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PD-1+ Polyfunctional T Cells Dominate the Periphery after Tumor-Infiltrating Lymphocyte Therapy for Cancer
dqp123, dqp123, Kjeldsen, J. W., Andersen, R., Westergaard, M. C. W., Bianchi, V., Legut, M., Attaf, M., Szomolay, B., Ott, S., Dolton, G., Lyngaa, R., Hadrup, S. R., Sewell, A. K. & Svane, Inge Marie, 2017, In: Clinical Cancer Research. 23, 19, p. 5779-5788Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PD-L1 expression and survival among melanoma patients treated with standard immunotherapy or chemotherapy
Steiniche, T., Vestergaard Danielsen, A., Wang, Z., Feng, Y., Switten Nielsen, P., Bastholt, L., Schmidt, H., Svane, Inge Marie, Dolled-Filhart, M., Emancipator, K., Weiner, R., Busch-Sørensen, M. & Zhou, W., 2017, In: Journal of the European Academy of Dermatology and Venereology. 31, 7, p. e319-e321Research output: Contribution to journal › Comment/debate › Research
- Published
Predictors of responses to immune checkpoint blockade in advanced melanoma
Jacquelot, N., Roberti, M. P., Enot, D. P., Rusakiewicz, S., Ternès, N., Jegou, S., Woods, D. M., Sodré, A. L., Hansen, M., Meirow, Y., Sade-Feldman, M., Burra, A., Kwek, S. S., Flament, C., Messaoudene, M., Duong, C. P. M., Chen, L., Kwon, B. S., Anderson, A. C., Kuchroo, V. K. & 30 others, , 2017, In: Nature Communications. 8, 13 p., 592.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Survival of metastatic melanoma patients after dendritic cell vaccination correlates with expression of leukocyte phosphatidylethanolamine-binding protein 1/Raf kinase inhibitory protein
Buschow, S. I., Ramazzotti, M., Reinieren-Beeren, I. M. J., Heinzerling, L. M., Westdorp, H., Stefanini, I., Beltrame, L., Hato, S. V., Ellebaek, E., Gross, S., Nguyen, V. A., Weinlich, G., Ragoussis, J., Baban, D., Schuler-Thurner, B., Svane, I. M., Romani, N., Austyn, J. M., De Vries, I. J. M., Schuler, G. & 2 others, , 2017, In: OncoTarget. 8, 40, p. 67439-67456 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The JAK2V617F mutation is a target for specific T cells in the JAK2V617F-positive myeloproliferative neoplasms
Holmström, M. O., Hjortso, M. D., Ahmad, S. M., Met, Özcan, Martinenaite, E., Riley, C., Straten, P., Svane, Inge Marie, Hasselbalch, Hans Carl & Andersen, Mads Hald, 2017, In: Leukemia. 31, p. 495-498Research output: Contribution to journal › Letter › Research › peer-review
- Published
The majority of patients with metastatic melanoma are not represented in pivotal phase III immunotherapy trials
dqp123, dqp123, Kimper-Karl, M. L., Høyer, K. L., Bastholt, L., Schmidt, H. & Svane, Inge Marie, 2017, In: European Journal of Cancer. 74, p. 89-95Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Isolated asymptomatic masseter muscle metastasis as first sign of metastatic disease in a patient with known melanoma
Gjorup, C. A., Hendel, Helle Westergren, Svane, Inge Marie & Hølmich, Lisbet Rosenkrantz, 1 Dec 2016, In: J P R A S Open. 10, p. 1-4 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The CALR exon 9 mutations are shared neoantigens in patients with CALR mutant chronic myeloproliferative neoplasms
Holmström, M. O., Riley, C. H., Svane, Inge Marie, Hasselbalch, H. C. & Andersen, Mads Hald, Dec 2016, In: Leukemia. 30, 12, p. 2413-2416 14 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
The Danish Melanoma Database
Hølmich, Lisbet Rosenkrantz, Klausen, S., Spaun, E., Schmidt, G., Gad, D., Svane, Inge Marie, Schmidt, H., Lorentzen, H. F. & Ibfelt, E. H., 25 Oct 2016, In: Clinical Epidemiology. 8, p. 543-548 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes
Bentzen, A. K., Marquard, A. M., Lyngaa, R., Saini, S. K., Ramskov, S., Donia, M., Such, L., Furness, A. J. S., McGranahan, N., Rosenthal, R., thor Straten, E. P., Szallasi, Z., Svane, Inge Marie, Swanton, C., Quezada, S. A., Jakobsen, S. N., Eklund, A. C. & Hadrup, S. R., Oct 2016, In: Nature Biotechnology. 34, 10, p. 1037-1045 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Therapeutic Vaccination against A Modified Minimal Survivin Epitope Induces Functional CD4 T Cells That Recognize Survivin-Expressing Cells
Nitschke, N. J., Bjoern, J., Met, Özcan, Svane, Inge Marie & Andersen, M. H., 1 Sep 2016, In: Scandinavian Journal of Immunology. 84, 3, p. 191-193 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
mRNA-transfected dendritic cell vaccine in combination with metronomic cyclophosphamide as treatment for patients with advanced malignant melanoma
Borch, T. H., Engell-Noerregaard, L., Iversen, T. Z., Ellebaek, E., Met, Özcan, Hansen, M., Andersen, Mads Hald, thor Straten, E. P. & Svane, Inge Marie, 1 Sep 2016, In: OncoImmunology. 5, 9, 12 p., e1207842.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Autocrine CCL19 blocks dendritic cell migration toward weak gradients of CCL21
Hansen, M., Met, Özcan, Larsen, N. B., Rosenkilde, Mette, Andersen, Mads Hald, Svane, Inge Marie & Hjortø, Gertrud Malene, Sep 2016, In: Cytotherapy. 18, 9, p. 1187-1196Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PD-L1 peptide co-stimulation increases immunogenicity of a dendritic cell-based cancer vaccine
Munir Ahmad, S., Martinenaite, E., Hansen, M., Junker, N., Borch, T. H., Met, Özcan, Donia, M., Svane, Inge Marie & Andersen, Mads Hald, 2 Aug 2016, In: OncoImmunology. 5, 8, e1202391.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cabazitaxel as second-line or third-line therapy in patients with metastatic castration-resistant prostate cancer
Kongsted, P., Svane, Inge Marie, Lindberg, H., Bisbjerg, R., Daugaard, G. & Sengeløv, L., Aug 2016, In: Anti-Cancer Drugs. 27, 7, p. 695-701 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long-Lasting Complete Responses in Patients with Metastatic Melanoma after Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes and an Attenuated IL2 Regimen
Andersen, R., Donia, M., Ellebæk, E., Borch, T. H., Kongsted, P., Iversen, T. Z., Hølmich, Lisbet Rosenkrantz, Hendel, Helle Westergren, Met, Özcan, Andersen, Mads Hald, Thor Straten, E. P. & Svane, Inge Marie, Aug 2016, In: Clinical Cancer Research. 22, 15, p. 3734-3745 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Safety, immune and clinical responses in metastatic melanoma patients vaccinated with a long peptide derived from indoleamine 2,3-dioxygenase in combination with ipilimumab
Bjørn, J., Iversen, T. Z., Nitschke, N. J., Andersen, Mads Hald & Svane, Inge Marie, Aug 2016, In: Cytotherapy. 18, 8, p. 1043-1055 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Behandlingen af BRAF-muteret metastatisk melanom med BRAF/MEK-inhibitorer bedrer prognosen
Boyles, T. B., Svane, Inge Marie, Bastholt, L. & Schmidt, H., 2016, In: Ugeskrift for Laeger. 178, 4 p., V02160126.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CCL22-specific T Cells: Modulating the immunosuppressive tumor microenvironment
Martinenaite, E., Munir Ahmad, S., Hansen, M., Met, Özcan, Westergaard, M. W., Larsen, S. K., Klausen, T. W., Donia, M., Svane, Inge Marie & Andersen, Mads Hald, 2016, In: OncoImmunology. 5, 11, 10 p., e1238541.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immuncheckpointantistoffer øger overlevelsen for patienter med metastatisk melanom
Fløe, L. E., Svane, Inge Marie, Bastholt, L. & Schmidt, H., 2016, In: Ugeskrift for Laeger. 178, 4 p., V01160070.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immune monitoring using mRNA-transfected dendritic cells
Borch, T. H., Svane, Inge Marie & Met, Özcan, 2016, Synthetic mRNA: Production, Introduction Into Cells, and Physiological Consequences. Humana Press, Vol. 1428. p. 245-259 15 p. (Methods in Molecular Biology, Vol. 1428).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Immunological correlates of treatment and response in stage IV malignant melanoma patients treated with Ipilimumab
Bjoern, J., Juul Nitschke, N., Zeeberg Iversen, T., Schmidt, H., Fode, K. & Svane, Inge Marie, 2016, In: OncoImmunology. 5, 4, 10 p., e1100788.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interferon-α induces marked alterations in circulating regulatory T cells, NK cell subsets, and dendritic cells in patients with JAK2V617F-positive essential thrombocythemia and polycythemia vera
Riley, C. H., Brimnes, M. K., Hansen, M., Jensen, M. K., Hasselbalch, Hans Carl, Kjaer, L., Straten, P. T. & Svane, Inge Marie, 2016, In: European Journal of Haematology. 97, 1, p. 83-92 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Large-scale mRNA transfection of dendritic cells by electroporation in continuous flow systems
Selmeczi, D., Hansen, T. S., Met, Özcan, Svane, Inge Marie & Larsen, N. B., 2016, Methods in Molecular Biology. Humana Press, Vol. 1428. p. 151-161 11 p. (Methods in Molecular Biology, Vol. 1428).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Peptide vaccination against multiple myeloma using peptides derived from anti-apoptotic proteins: a phase I trial
Jørgensen, N. G., Ahmad, S. M., Abildgaard, N., Straten, P. T., Svane, Inge Marie, Andersen, Mads Hald & Knudsen, L. M., 2016, In: Stem Cell Investigation. 3, 5 p., 95.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Predictors of Chemotherapy-Induced Toxicity and Treatment Outcomes in Elderly Versus Younger Patients With Metastatic Castration-Resistant Prostate Cancer
Kongsted, P., Svane, Inge Marie, Lindberg, H. & Sengeløv, L., 2016, In: Clinical Genitourinary Cancer. 14, 6, p. e559-e568Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The controversial role of TNF in melanoma
Donia, M., Kjeldsen, J. W. & Svane, Inge Marie, 2016, In: OncoImmunology. 5, 4, 2 p., e1107699.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Transfection of tumor-infiltrating T cells with mRNA encoding CXCR2
Idorn, M., thor Straten, E. P., Svane, Inge Marie & Met, Özcan, 2016, Synthetic mRNA: Production, Introduction Into Cells, and Physiological Consequences. Rhoads, R. E. (ed.). Springer, Vol. 1428. p. 261-276 16 p. (Methods in Molecular Biology, Vol. 1428).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- 2015
- Published
Tumor-infiltrating lymphocytes for the treatment of metastatic cancer
Geukes Foppen, M. H., Donia, M., Svane, Inge Marie & Haanen, J. B. A. G., Dec 2015, In: Molecular Oncology. 9, 10, p. 1918-35 18 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Low-dose prednisolone in first-line docetaxel for patients with metastatic castration-resistant prostate cancer: is there a clinical benefit?
Kongsted, P., Svane, Inge Marie, Lindberg, H., Daugaard, G. & Sengeløv, L., Nov 2015, In: Urologic Oncology: Seminars and Original Investigations. 33, 11, p. 494.e15-20Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Design and validation of conditional ligands for HLA-B*08:01, HLA-B*15:01, HLA-B*35:01, and HLA-B*44:05
Frøsig, T. M., Yap, J., Seremet, T., Lyngaa, R., Svane, Inge Marie, Thor Straten, P., Heemskerk, M. H. M., Grotenbreg, G. M. & Hadrup, S. R., Oct 2015, In: Cytometry. Part A. 87, 10, p. 967-75 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aberrant Expression of MHC Class II in Melanoma Attracts Inflammatory Tumor-Specific CD4+ T- Cells, Which Dampen CD8+ T-cell Antitumor Reactivity
Donia, M., Andersen, R., Kjeldsen, J. W., Fagone, P., Munir, S., Nicoletti, F., Andersen, Mads Hald, Thor Straten, P. & Svane, Inge Marie, 15 Sep 2015, In: Cancer Research. 75, 18, p. 3747-59 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
More tricks with tetramers: a practical guide to staining T cells with peptide-MHC multimers
Dolton, G., Tungatt, K., Lloyd, A., Bianchi, V., Theaker, S. M., Trimby, A., Holland, C. J., Donia, M., Godkin, A. J., Cole, D. K., Straten, P. T., Peakman, M., Svane, Inge Marie & Sewell, A. K., Sep 2015, In: Immunology. 146, 1, p. 11-22 12 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Reorienting the immune system in the treatment of cancer by using anti-PD-1 and anti-PD-L1 antibodies
Borch, T. H., Donia, M., Andersen, Mads Hald & Svane, Inge Marie, Sep 2015, In: Drug Discovery Today. 20, 9, p. 1127-34 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Broadening the repertoire of melanoma-associated T-cell epitopes
Frøsig, T. M., Lyngaa, R., Met, Özcan, Larsen, S. K., Donia, M., Svane, Inge Marie, Thor Straten, P. & Hadrup, S. R., May 2015, In: Cancer immunology, immunotherapy : CII. 64, 5, p. 609-20 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuroprotective and anti-inflammatory mechanisms are activated early in optic neuritis
Tsakiri, A., Ravanidis, S., Lagoudaki, R., Poulatsidou, K., Svane, Inge Marie, Fredriksen, Jette Lautrup & Grigoriadis, N., May 2015, In: Acta Neurologica Scandinavica. 131, 5, p. 305-12 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Confinement dependent chemotaxis in two-photon polymerized linear migration constructs with highly definable concentration gradients
Hjortø, Gertrud Malene, Olsen, M. H., Svane, Inge Marie & Larsen, N. B., Apr 2015, In: Biomedical Microdevices. 17, 2, p. 1-10 10 p., 30.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial
Weber, J. S., D'Angelo, S. P., Minor, D., Hodi, F. S., Gutzmer, R., Neyns, B., Hoeller, C., Khushalani, N. I., Miller, W. H., Lao, C. D., Linette, G. P., Thomas, L., Lorigan, P., Grossmann, K. F., Hassel, J. C., Maio, M., Sznol, M., Ascierto, P. A., Mohr, P., Chmielowski, B. & 8 others, , Apr 2015, In: Lancet Oncology. 16, 4, p. 375-84 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expansion of circulating CD56bright natural killer cells in patients with JAK2-positive chronic myeloproliferative neoplasms during treatment with interferon-α
Riley, C. H., Hansen, M., Brimnes, M. K., Hasselbalch, H. C., Bjerrum, O. W., Straten, P. T., Svane, Inge Marie & Jensen, M. K., Mar 2015, In: European Journal of Haematology. 94, 3, p. 227–234 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antibody Stabilization of Peptide–MHC Multimers Reveals Functional T Cells Bearing Extremely Low-Affinity TCRs
Tungatt, K., Bianchi, V., Crowther, M. D., Powell, W. E., Schauenburg, A. J., Trimby, A., Donia, M., Miles, J. J., Holland, C. J., Cole, D. K., Godkin, A. J., Peakman, M., Straten, P. T., Svane, Inge Marie, Sewell, A. K. & Dolton, G., Jan 2015, In: Journal of immunology (Baltimore, Md. : 1950). 194, 1, p. 463-474 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Targeting of Indoleamine 2,3 Dioxygenase -Mediated Immune Escape in Cancer
Iversen, T. Z., Andersen, Mads Hald & Svane, Inge Marie, Jan 2015, In: Basic & Clinical Pharmacology & Toxicology. 116, 1, p. 19-24 6 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Tryptophan 2,3-dioxygenase (TDO)-reactive T cells differ in their functional characteristics in health and cancer
Hjortsø, M. D., Larsen, S. K., Kongsted, P., Met, Özcan, Frøsig, T. M., Andersen, G. H., Ahmad, S. M., Svane, Inge Marie, Becker, J. C., Straten, P. T. & Andersen, Mads Hald, Jan 2015, In: OncoImmunology. 4, 1, e968480.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Indoleamine 2,3-dioxygenase vaccination
Andersen, Mads Hald & Svane, Inge Marie, 2015, In: OncoImmunology. 4, 1, p. 1-3 3 p., e983770.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tumor infiltrating lymphocyte therapy for ovarian cancer and renal cell carcinoma
Andersen, R., Donia, M., Westergaard, M. C. W., Pedersen, M., Hansen, M. & Svane, Inge Marie, 2015, In: Human Vaccines & Immunotherapeutics. 11, 12, p. 2790-5 6 p.Research output: Contribution to journal › Comment/debate › Research
- 2014
- Published
Successful treatment with Ipilimumab and Interleukin‑2 in two patients with metastatic melanoma and systemic autoimmune disease
Pedersen, M., Andersen, R., Larsen, P. N., Jacobsen, Søren, Thielsen, P., Thor Straten, P. & Svane, Inge Marie, Dec 2014, In: Cancer immunology, immunotherapy : CII. 63, 12, p. 1341-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simplified protocol for clinical-grade tumor-infiltrating lymphocyte manufacturing with use of the Wave bioreactor
Donia, M., Larsen, S. M., Met, Özcan & Svane, Inge Marie, Aug 2014, In: Cytotherapy. 16, 8, p. 1117–1120 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Late development of splenic sarcoidosis-like lesions in a patient with metastatic melanoma and long-lasting clinical response to ipilimumab
Andersen, R., Nørgaard, P. H., Al-Jailawi, M. K. M. & Svane, Inge Marie, 23 Jan 2014, In: OncoImmunology. 3, 8, e954506.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long-lasting Disease Stabilization in the Absence of Toxicity in Metastatic Lung Cancer Patients Vaccinated with an Epitope Derived from Indoleamine 2,3 Dioxygenase
Iversen, T. Z., Engell-Noerregaard, L., Ellebaek, E., Andersen, R. S., Larsen, S. K., Bjoern, J., Zeyher, C., Gouttefangeas, C., Thomsen, B. M., Holm, B., Thor Straten, P., Mellemgaard, A., Andersen, Mads Hald & Svane, Inge Marie, 1 Jan 2014, In: Clinical Cancer Research. 20, 1, p. 221-232 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spontaneous presence of FOXO3-specific T cells in cancer patients
Larsen, S. K., Ahmad, S. M., Idorn, M., Met, Özcan, Martinenaite, E., Svane, Inge Marie, Straten, P. T. & Andersen, Mads Hald, 1 Jan 2014, In: OncoImmunology. 3, 8, e953411.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4054758
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Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma
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257
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T cell recognition of novel shared breast cancer antigens is frequently observed in peripheral blood of breast cancer patients
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189
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Survival of metastatic melanoma patients after dendritic cell vaccination correlates with expression of leukocyte phosphatidylethanolamine-binding protein 1/Raf kinase inhibitory protein
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