Filip Krag Knop

Filip Krag Knop

Clinical Professor

Member of:

  • Internal Medicine: Endocrinology


  1. Published

    Gluco-metabolic response to exogenous oxytocin in totally pancreatectomized patients and healthy individuals

    Kliim-Hansen, V., Gether, I. M., Juel, C. T., Ellegaard, A., Pedersen, M. G., Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Lund, Asger Bach, Gasbjerg, Lærke Smidt & Knop, Filip Krag, 2024, In: Peptides. 179, 5 p., 171242.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    The impact of type 2 diabetes and glycaemic control on mortality and clinical outcomes in hospitalized patients with COVID-19 in the capital region of Denmark

    Kliim-Hansen, V., Johansson, K. S., Gasbjerg, Lærke Smidt, Solem, Espen Victor Jimenez, Petersen, Tonny Studsgaard, Nyeland, M. E., Winther-Jensen, M., Ankarfeldt, Mikkel Zöllner, Pedersen, M. G., Ellegaard, A. M., Knop, Filip Krag & Christensen, Mikkel Bring, 2023, In: Diabetes, Obesity and Metabolism. 26, 1, p. 160-168 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Protocol for a 30-day randomised, parallel-group, non-inferiority, controlled trial investigating the effects of discontinuing renin-angiotensin system inhibitors in patients with and without COVID-19: The RASCOVID-19 trial

    Kliim-Hansen, V., Gasbjerg, Lærke Smidt, Ellegaard, A. M., Lorentsson, H. J. N., Lynggaard, M. B., Hagemann, C. A., Legart, C., Mathiesen, D. S., Sivapalan, P., Jensen , Jens-Ulrik Stæhr , Vilsbøll, Tina, Christensen, Mikkel Bring & Knop, Filip Krag, 2022, In: BMJ Open. 12, 11, e062895.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Inappropriate suppression of glucagon during OGTT but not during isoglycaemic i.v. glucose infusion contributes to the reduced incretin effect in type 2 diabetes mellitus

    Knop, Filip Krag, Vilsbøll, T., Madsbad, Sten, Holst, Jens Juul & Krarup, T., Apr 2007, In: Diabetologia. 50, 4, p. 797-805 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Glucagon suppression during OGTT worsens while suppression during IVGTT sustains alongside development of glucose intolerance in patients with chronic pancreatitis

    Knop, Filip Krag, Vilsbøll, Tina, Larsen, S., Madsbad, Sten, Holst, Jens Juul & Krarup, T. M., 24 Sep 2010, In: Regulatory Peptides. 164, 2-3, p. 144-50 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Thirty days of resveratrol supplementation does not affect postprandial incretin hormone responses, but suppresses postprandial glucagon in obese subjects

    Knop, Filip Krag, Konings, E., Timmers, S., Schrauwen, P., Holst, Jens Juul & Blaak, E. E., 11 May 2013, In: Diabetic Medicine. 30, 10, p. 1214-1218 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Time spent in glycaemic control after initiating treatment with oral semaglutide vs empagliflozin: an exploratory analysis of the PIONEER 2 trial

    Knop, Filip Krag, Cariou, B., Christiansen, E., Davies, A. L., Montanya, E., Abildlund, M. T. & Rosenstock, J., 2021, In: Diabetologia. 64, SUPPL 1, p. 249-250 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  8. Published

    Inappropriate suppression of glucagon during OGTT but not during isoglycaemic i.v. glucose infusion contributes to the reduced incretin effect in type 2 diabetes mellitus

    Knop, F. K., Vilsbøll, Tina, Madsbad, Sten, Holst, Jens Juul, Krarup, T., Knop, Filip Krag, Vilsbøll, Tina, Madsbad, Sten, Holst, J. M. & Krarup, T., 1 Apr 2007, In: Diabetologia. 50, 4, p. 797-805 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Replacing SUs with incretin-based therapies for type 2 diabetes mellitus: challenges and feasibility

    Knop, Filip Krag, Holst, Jens Juul & Vilsbøll, T., Jul 2008, In: I Drugs: the Investigational Drugs Journal. 11, 7, p. 497-501 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Incretin-based therapy of type 2 diabetes mellitus

    Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 2009, In: Current Protein and Peptide Science. 10, 1, p. 46-55 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    No hypoglycemia after subcutaneous administration of glucagon-like peptide-1 in lean type 2 diabetic patients and in patients with diabetes secondary to chronic pancreatitis.

    Knop, Filip Krag, Vilsbøll, Tina, Larsen, S., Madsbad, Sten, Holst, J. J. & Krarup, T., 2003, In: Diabetes Care. 26, 9, p. 2581-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    The impact of pancreatic enzyme supplementation on postprandial responses of glucagon-like Peptide-2 in patients with chronic pancreatitis and pancreatic exocrine insufficiency

    Knop, Filip Krag, Vilsbøll, Tina, Lund, A., Krarup, T., Holst, Jens Juul & Hornum, Mads, 6 Sep 2010, In: Journal of the Pancreas. 11, 5, p. 489-91 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Unprecedented high insulin secretion in a healthy human subject after intravenous glucagon-like peptide-1: a case report

    Knop, Filip Krag, Lund, Asger Bach, Madsbad, Sten, Holst, Jens Juul, Krarup, T. & Vilsbøll, T., 2014, In: BMC Research Notes. 7, p. 1-6 6 p., 326.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Impaired incretin effect and fasting hyperglucagonaemia characterizing type 2 diabetic subjects are early signs of dysmetabolism in obesity

    Knop, Filip Krag, Aaboe, K., Vilsbøll, Tina, Vølund, A., Holst, Jens Juul, Krarup, T. & Madsbad, Sten, 2012, In: Diabetes, Obesity and Metabolism. 14, 6, p. 500-510 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    A gut feeling about glucagon: Eje Prize 2018

    Knop, Filip Krag, 2018, In: European Journal of Endocrinology. 178, 6, p. R267-R280 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    Exenatide: pharmacokinetics, clinical use, and future directions

    Knop, Filip Krag, Bronden, A. & Vilsbøll, Tina, 2017, In: Expert Opinion on Pharmacotherapy. 18, 6, p. 555-571 17 p.

    Research output: Contribution to journalReviewResearchpeer-review

  17. Published

    Oral semaglutide 50 mg taken once per day in adults with overweight or obesity (OASIS 1): a randomised, double-blind, placebo-controlled, phase 3 trial

    OASIS 1 Investigators, O. 1. I., 2023, In: The Lancet. 402, 10403, p. 705-719 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Bile-induced secretion of glucagon-like peptide-1: pathophysiological implications in type 2 diabetes?

    Knop, Filip Krag, 1 Jul 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 299, 1, p. E10-3

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Small-bowel hemangiosarcoma and capsule endoscopy

    Knop, Filip Krag, Hansen, M. B. & Meisner, S., 1 Jul 2003, In: Endoscopy. 35, 7, p. 637

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Comment on: Villareal et al. (2009) TCF7L2 variant rs7903146 affects the risk of type 2 diabetes by modulating incretin action. Diabetes;59:479-485

    Knop, Filip Krag, 1 Jun 2010, In: Diabetes. 59, 6, p. e4; author reply e5-6

    Research output: Contribution to journalLetterResearchpeer-review

  21. Published

    Glucagon-like peptide 1-baseret behandling af type 2-diabetes mellitus

    Knop, Filip Krag & Vilsbøll, Tina, 28 May 2007, In: Ugeskrift for Laeger. 169, 22, p. 2095-9 5 p.

    Research output: Contribution to journalReviewResearchpeer-review

  22. Published

    Comment on: Chen et al. Utilizing the Second-Meal Effect in Type 2 Diabetes: Practical Use of a Soya-Yogurt Snack. Diabetes Care 2010;33:2552-2554

    Knop, Filip Krag, 1 Apr 2011, In: Diabetes Care. 34, 4, p. e44

    Research output: Contribution to journalLetterResearchpeer-review

  23. Published

    Delayed ischemic cecal perforation despite optimal decompression after placement of a self-expanding metal stent: report of a case

    Knop, Filip Krag, Pilsgaard, B., Meisner, S. & Wille-Jørgensen, P., 1 Nov 2004, In: Diseases of the Colon and Rectum. 47, 11, p. 1970-3 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Resolution of type 2 diabetes following gastric bypass surgery: involvement of gut-derived glucagon and glucagonotropic signalling?

    Knop, Filip Krag, 2009, In: Diabetologia. 52, 11, p. 2270-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Vaerdien af billeddiagnostiske undersøgelser ordineret i almen praksis

    Knop, Filip Krag & Stauning, J. A., 20 Feb 2006, In: Ugeskrift for Laeger. 168, 8, p. 794-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Incretin hormones and beta cell function in chronic pancreatitis

    Knop, Filip Krag, 1 Jul 2010, In: Danish Medical Bulletin (Online). 57, 7, p. B4163

    Research output: Contribution to journalReviewResearchpeer-review

  27. Published

    Clinical characteristics and glucose-lowering drug utilization among patients initiating liraglutide in Denmark: a routine clinical care prescription study

    Knudsen, J. S., Thomsen, R. W., Pottegard, A., Knop, Filip Krag & Sørensen, H. T., 2019, In: Journal of Diabetes. 11, 8, p. 690-694

    Research output: Contribution to journalLetterResearchpeer-review

  28. Published

    Differences Between Randomized Clinical Trial Patients and Real-World Initiators of the Glucagon-Like Peptide 1 Receptor Agonist Liraglutide

    Knudsen, J. S., Thomsen, R. W., Pottegård, A., Knop, Filip Krag & Sørensen, H. T., 2018, In: Diabetes Care. 41, 9, p. e133-e135 3 p.

    Research output: Contribution to journalLetterResearchpeer-review

  29. Published

    Improvement of Insulin Sensitivity after Lean Donor Feces in Metabolic Syndrome Is Driven by Baseline Intestinal Microbiota Composition

    Kootte, R. S., Levin, E., Salojärvi, J., Smits, L. P., Hartstra, A. V., Udayappan, S. D., Hermes, G., Bouter, K. E., Koopen, A. M., Holst, J. J., Knop, F. K., Blaak, E. E., Zhao, J., Smidt, H., Harms, A. C., Hankemeijer, T., Bergman, J. J. G. H. M., Romijn, H. A., Schaap, F. G., Olde Damink, S. W. M. & 8 others, Ackermans, M. T., Dallinga-Thie, G. M., Zoetendal, E., de Vos, W. M., Serlie, M. J., Stroes, E. S. G., Groen, A. K. & Nieuwdorp, M., Oct 2017, In: Cell Metabolism. 26, 4, p. 611-619.e6 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Transcutaneous vagal nerve stimulation for treating gastrointestinal symptoms in individuals with diabetes: a randomised, double-blind, sham-controlled, multicentre trial

    Kornum, D. S., Bertoli, D., Kufaishi, H., Wegeberg, A., Okdahl, T., Mark, E. B., Høyer, K. L., Frøkjær, J. B., Brock, Birgitte, Krogh, K., Hansen, C. S., Knop, Filip Krag, Brock, C. & Drewes, A. M., 2024, In: Diabetologia. 67, 6, p. 1122-1137

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Continuous glucose monitoring in pregnant women with type 1 diabetes: an observational cohort study of 186 pregnancies

    Kristensen, K., Ögge, L. E., Sengpiel, V., Kjölhede, K., Dotevall, A., Elfvin, A., Knop, Filip Krag, Wiberg, N., Katsarou, A., Shaat, N., Kristensen, L. & Berntorp, K., 2019, In: Diabetologia. 62, 7, p. 1143-1153 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    The naturally occurring GIP(1-30)NH2 is a GIP receptor agonist in humans

    Krogh, L. S. L., Henriksen, K., Stensen, S., Skov-Jeppesen, Kirsa, Bergmann, N. C., Størling, Joachim, Rosenkilde, Mette, Hartmann, Bolette, Holst, Jens Juul, Gasbjerg, Lærke Smidt & Knop, Filip Krag, 2023, In: European Journal of Endocrinology. 188, 1, lvac015.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Biomarkører for kardiovaskulær sygdom ved type 2-diabetes

    Krogh, S. K., Andersen, A., Knop, Filip Krag & Vilsbøll, Tina, 2019, In: Ugeskrift for Laeger. 181, 6 p., V10180711.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Evidence connecting old, new and neglected glucose-lowering drugs to bile acid-induced GLP-1 secretion: a review

    Kårhus, M. L., Brønden, A., Sonne, D. P., Vilsbøll, Tina & Knop, Filip Krag, Sep 2017, In: Diabetes, Obesity and Metabolism. 19, 9, p. 1214-1222

    Research output: Contribution to journalReviewResearchpeer-review

  35. Published

    Safety and efficacy of liraglutide versus colesevelam for the treatment of bile acid diarrhoea: A randomised, double-blind, active-comparator, non-inferiority clinical trial

    Kårhus, M. L., Brønden, A., Forman, Julie Lyng, Haaber, A., Knudsen, E., Langholz, Ebbe, Dragsted, Lars Ove, Hansen, S. H., Krakauer, M., Vilsbøll, Tina, Sonne, David Peick & Knop, Filip Krag, 2022, In: The Lancet Gastroenterology and Hepatology. 7, 10, p. 922-931 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Remission of Bile Acid Malabsorption Symptoms Following Treatment With the Glucagon-Like Peptide 1 Receptor Agonist Liraglutide

    Kårhus, M. L., Brønden, A., Roder, M. E., Leotta, S., Sonnet, D. P. & Knop, Filip Krag, 2019, In: Gastroenterology. 157, 2, p. 569-571

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Liraglutide versus colesevelam for treating bile acid diarrhoea – Authors' reply

    Kårhus, M. L. & Knop, Filip Krag, 2022, In: The Lancet Gastroenterology and Hepatology. 7, 12, p. 1075-1076 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  38. Published

    The Epidemiology of Bile Acid Diarrhea in Denmark

    Kårhus, M. L., Ellegaard, A. M., Winther-Jensen, M., Hansen, S., Knop, Filip Krag & Kårhus, L. L., 2023, In: Clinical Epidemiology. 15, p. 1173-1181 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    The Epidemiology of Bile Acid Diarrhea in Denmark [Response to Letter]

    Kårhus, M. L., Ellegaard, A. M., Knop, Filip Krag & Kårhus, L. L., 2024, In: Clinical Epidemiology. 16, p. 7-8 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  40. Published

    Different Effects of Once-weekly and Once-daily Administered GLP-1RA Semaglutide and Liraglutide on Bile Acid Diarrhea

    Kårhus, M. L., Knudsen, E. & Knop, Filip Krag, 2023, In: JCEM case reports. 1, 1, 3 p., luac004.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Enterohepatic, gluco-metabolic, and gut microbial characterization of individuals with bile acid malabsorption

    Kårhus, M. L., Sonne, David Peick, Thomasen, M., Ellegaard, A., Holst, Jens Juul, Rehfeld, Jens Frederik, Chávez-Talavera, O., Tailleux, A., Staels, B., Nielsen, Dennis Sandris, Dragsted, Lars Ove, Vilsbøll, Tina, Brønden, A. & Knop, Filip Krag, 2022, In: Gastro Hep Advances. 1, 3, p. 299-312 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published
  43. Published

    The bile-gut axis and metabolic consequences of cholecystectomy

    Lange, A. H., Pedersen, M. G., Ellegaard, A. M., Nerild, H. H., Brønden, Andreas, Sonne, David Peick & Knop, Filip Krag, 2024, In: European Journal of Endocrinology. 190, 4, p. R1-R9 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  44. Published

    Fibroblast growth factor 21 is the main alcohol responsive peptide hormone in humans and individuals with alcohol use disorder exihibit increased plasma concentrations after alcohol intake

    Lanng, A., Gasbjerg, Lærke Smidt, Sucksdorff, A., Svenningsen, J., Trammell, Sam, Vilsbøll, Tina, Gillum, M. & Knop, Filip Krag, 2022, In: Journal of Hepatology. 77, S1, p. S121-S121 1 p., THU006.

    Research output: Contribution to journalConference abstract in journalResearch

  45. Published

    The effect of acute intragastric vs. intravenous alcohol administration on inflammation markers, blood lipids and gallbladder motility in healthy men

    Lanng, A. R., Gasbjerg, Lærke Smidt, Bergmann, N. C., Gillum, M. P., Rehfeld, Jens Frederik, Helsted, M. M., Møller, H. J., Grønbæk, H., Vilsbøll, Tina & Knop, Filip Krag, 2020, In: Alcohol. 87, p. 29-37 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    The Effect of Ethanol on Inflammation Markers and FGF-21 in Healthy Individuals

    Lanng, A. R., Gasbjerg, Lærke Smidt, Bergmann, N. C., Møller, H., Gillum, M., Gronbaek, H., Vilsbøll, Tina & Knop, Filip Krag, 2018, In: Diabetes. 67, Supplement 1, 2415-PUB.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Gluco-metabolic effects of oral and intravenous alcohol administration in men

    Lanng, A. R., Gasbjerg, Lærke Smidt, Bergmann, N. C., Bergmann, S., Heisted, M. M., Gillum, M. P., Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2019, In: Endocrine Connections. 8, 10, p. 1372-1382

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Julefrokostdilemmaet

    Lanng, A. R., Gasbjerg, L. S. & Knop, Filip Krag, 11 Dec 2017, In: Ugeskrift for Laeger. 179, 25, p. 2212-15 4 p., V69590.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Changes in oxidative RNA and DNA modifications following one-week treatment with sevelamer: two randomized, placebo-controlled trials

    Larsen, E. L., Brønden, A., Karstoft, K., Henriksen, T., Vilsbøll, Tina, Poulsen, Henrik Enghusen & Knop, Filip Krag, 2018, In: Free Radical Biology and Medicine. 128, p. S118 280.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  50. Published

    The effect of empagliflozin on oxidative nucleic acid modifications in patients with type 2 diabetes: Protocol for a randomised, double-blinded, placebo-controlled trial

    Larsen, E. L., Cejvanovic, V., Kjær, L. K., Vilsbøll, Tina, Knop, Filip Krag, Rungby, Jørgen & Poulsen, Henrik Enghusen, May 2017, In: BMJ Open. 7, 5, 6 p., e014728.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Differential time responses in inflammatory and oxidative stress markers after a marathon: An observational study

    Larsen, E. L., Poulsen, Henrik Enghusen, Michaelsen, C., Kjær, L. K., Lyngbæk, M., Andersen, Emilie Skytte, Petersen-Bønding, C., Lemoine, C., Gillum, M., Jørgensen, Niklas Rye, Ploug, Thorkil, Vilsbøll, Tina, Knop, Filip Krag & Karstoft, K., 2020, In: Journal of Sports Sciences. 38, 18, p. 2080-2091

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Changes in urinary excretion of oxidative nucleic acid modifications in the week following Copenhagen Marathon 2018, Denmark

    Larsen, E. L., Kjær, L. K., Michaelsen, C., Andersen, E., Lyngbæk, M., Petersen-bønding, C., Henriksen, T., Vilsbøll, Tina, Knop, Filip Krag, Ploug, Thorkil, Poulsen, Henrik Enghusen & Karstoft, K., 2018, In: Free Radical Biology and Medicine. 128, S1, p. S54

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  53. Published

    Effects of two- and twelve-weeks sodium-glucose cotransporter 2 inhibition on DNA and RNA oxidation: two randomized, placebo-controlled trials

    Larsen, E. L., Andersen, A., Kjær, L. K., Eickhoff, M. K., Frimodt-Møller, M., Persson, F., Rossing, Peter, Lykkesfeldt, Jens, Knop, Filip Krag, Vilsbøll, Tina, Rungby, Jørgen & Poulsen, Henrik Enghusen, 2023, In: Free Radical Research. 57, 2, p. 140-151

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Echocardiographic abnormalities and predictors of mortality in hospitalized COVID-19 patients: the ECHOVID-19 study

    Lassen, M. C. H., Skaarup, K. G., Lind, J. N., Alhakak, A. S., Sengeløv, M., Nielsen, A. B., Espersen, C., Ravnkilde, K., Hauser, R., Schöps, L. B., Holt, E., Johansen, N. D., Modin, D., Djernæs, K., Graff, C., Bundgaard, H., Hassager, C., Jabbari, R., Carlsen, J., Lebech, A-M. & 28 others, Kirk, Ole, Bodtger, U., Lindholm, M. G., Joseph, G., Wiese, L., Schiødt, Frank Vinholt, Kristiansen, O. P., Walsted, E. S., Nielsen, Olav Wendelboe, Lindegaard, Birgitte, Tønder, N., Benfield, Thomas, Jeschke, K. N., Ulrik, Charlotte Suppli, Knop, Filip Krag, Lamberts, Morten Kjøbek, Sivapalan, P., Gislason, Gunnar Hilmar, Marott, J. L., Møgelvang, R., Jensen, G., Schnohr, P., Søgaard, P., Solomon, S. D., Iversen, Kasper, Jensen , Jens-Ulrik Stæhr , Schou, Morten & Biering-Sørensen, Tor, 2020, In: ESC heart failure. 7, 6, p. 4189-4197

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Oral glucose has little or no effect on appetite and satiety sensations despite a significant gastrointestinal response

    Lauritsen, J. V., Bergmann, N., Junker, A. E., Gyldenløve, Mette, Skov, Lone, Gluud, Lise Lotte, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: European Journal of Endocrinology. 189, 6, p. 619-626 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Bariatric surgery in patients with non-alcoholic fatty liver disease from pathophysiology to clinical effects

    Laursen, T. L., Hagemann, C. A., Wei, C., Kazankov, K., Thomsen, K. L., Knop, Filip Krag & Gronbaek, H., 2019, In: World Journal of Hepatology. 11, 2, p. 138-149

    Research output: Contribution to journalReviewResearchpeer-review

  57. Published

    Adaptive changes in pancreas post Roux-en-Y gastric bypass induced weight loss

    Lautenbach, A., Wernecke, M., Riedel, N., Veigel, J., Yamamura, J., Keller, S., Jung, R., Busch, P., Mann, O., Knop, Filip Krag, Holst, Jens Juul, Meier, J. J. & Aberle, J., Oct 2018, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 34, 7, p. 1-8 e3025.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Serum lipidome unravels a diagnostic potential in bile acid diarrhoea

    Lewinska, M., Kårhus, M. L., Ellegaard, A. G., Romero-Gómez, M., Macias, R. I. R., Andersen, Jesper Bøje & Knop, Filip Krag, 2023, In: Gut. 72, 9, p. 1698-1708

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    The altered serum lipidome and its diagnostic potential for Non-Alcoholic Fatty Liver (NAFL)-associated hepatocellular carcinoma: Diagnosis of NAFLD-HCC utilising serum lipidomics

    Lewinska, M., Santos-Laso, A., Arretxe, E., Alonso, C., Zhuravleva, E., Jimenez-Agüero, R., Eizaguirre, E., Pareja, M. J., Romero-Gómez, M., Jimenez, M. A., Suppli, M. P., Knop, F. K., Oversoe, S. K., Villadsen, G. E., Decaens, T., Carrilho, F. J., de Oliveira, C. PMS., Sangro, B., Macias, R. I. R., Banales, J. M. & 1 others, Andersen, Jesper Bøje, 2021, In: EBioMedicine. 73, 103661.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Genetic variation in the two-pore domain potassium channel, TASK-1, may contribute to an atrial substrate for arrhythmogenesis

    Liang, B., Soka, M., Christensen, Alex Hørby, Olesen, Morten Steen Salling, Larsen, A. P., Knop, Filip Krag, Wang, F., Nielsen, J. B., Andersen, M. N., Humphreys, D., Mann, S. A., Huttner, I. G., Vandenberg, J. I., Svendsen, Jesper Hastrup, Haunsø, Stig, Preiss, T., Seebohm, G., Olesen, Søren-Peter, Schmitt, Nicole & Fatkin, D., 27 Dec 2013, In: Journal of Molecular and Cellular Cardiology. 67, p. 69-76 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Circulating levels of endothelial progenitor cells are associated with better cognitive function in older adults with glucagon-like peptide 1 receptor agonist-treated type 2 diabetes

    Longo, M., Di Meo, I., Caruso, P., Muscio, M. F., Scappaticcio, L., Maio, A., Maiorino, M. I., Bellastella, G., Signoriello, G., Knop, Filip Krag, Rizzo, M. R. & Esposito, K., 2023, In: Diabetes Research and Clinical Practice. 200, 7 p., 110688.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Empagliflozin decreases fasting and postprandial hyperglycaemia in totally pancreatectomised patients: a randomised, double-blinded, placebo-controlled study

    Lund, A., Baekdal, M., Nielsen, S. W., Hansen, C. P., Storkholm, J. H., Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2020, In: Diabetologia. 63, Suppl. 1, p. S276 1 p., 574.

    Research output: Contribution to journalConference abstract in journalResearch

  63. Published

    Glucagon elimination is increased in patients with type 2 diabetes

    Lund, A. B., Grøndahl, M. F., Bagger, J. I., Holst, Jens Juul, Christensen, M., Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Diabetologia. 60, p. S240-S240

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  64. Published

    Emerging GLP-1 receptor agonists

    Lund, A., Knop, Filip Krag & Vilsbøll, Tina, 2011, In: Expert Opinion on Emerging Drugs. 16, 4, p. 607-18 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Higher Endogenous Glucose Production during OGTT vs Isoglycemic Intravenous Glucose Infusion

    Lund, Asger Bach, Bagger, J. I., Christensen, Mikkel Bring, Grøndahl, M., van Hall, Gerrit, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Nov 2016, In: The Journal of Clinical Endocrinology & Metabolism. 101, 11, p. 4377-4384

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Extrapancreatic glucagon: Present status

    Lund, A. & Knop, Filip Krag, 2019, In: Diabetes Research and Clinical Practice. 147, p. 19-28

    Research output: Contribution to journalReviewResearchpeer-review

  67. Published

    Evidence of Extrapancreatic Glucagon Secretion in Man

    Lund, Asger Bach, Bagger, J. I., Albrechtsen, Nicolai Jacob Wewer, Christensen, M., Grøndahl, M., Hartmann, Bolette, Mathiesen, Elisabeth, Hansen, C. P., Storkholm, J. H., van Hall, Gerrit, Rehfeld, Jens Frederik, Hornburg, D., Meissner, F., Mann, Matthias, Larsen, S., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Mar 2016, In: Diabetes. 65, 3, p. 585-597 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    The separate and combined impact of the intestinal hormones, GIP, GLP-1, and GLP-2, on glucagon secretion in type 2 diabetes

    Lund, Asger Bach, Vilsbøll, Tina, Bagger, J. I., Holst, Jens Juul & Knop, Filip Krag, 2011, In: American Journal of Physiology: Endocrinology and Metabolism. 300, 6, p. E1038-E1046 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Erratum: Evidence of extrapancreatic glucagon secretion in man. Diabetes 2016;65:585-597

    Lund, Asger Bach, Bagger, J. I., Albrechtsen, Nicolai Jacob Wewer, Christensen, M., Grøndahl, M., Hartmann, Bolette, Mathiesen, Elisabeth, Hansen, C. P., Storkholm, J. H., van Hall, Gerrit, Rehfeld, Jens Frederik, Hornburg, D., Meissner, F., Mann, Matthias, Larsen, S., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 1 Jun 2016, In: Diabetes. 65, 6, p. 1752 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  70. Published

    Glucagon and type 2 diabetes: the return of the alpha cell

    Lund, Asger Bach, Bagger, J. I., Christensen, M., Knop, Filip Krag & Vilsbøll, T., Dec 2014, In: Current Diabetes Reports. 14, 12, p. 1-7 7 p., 555.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    L-cell Differentiation Is Induced by Bile Acids Through GPBAR1 and Paracrine GLP-1 and Serotonin Signaling

    Lund, M. L., Sorrentino, G., Egerod, Kristoffer Lihme, Kroone, C., Mortensen, B., Knop, Filip Krag, Reimann, F., Gribble, F. M., Drucker, D. J., De Koning, E. J. P., Schoonjans, K., Bäckhed, F., Schwartz, Thue W. & Petersen, N., Apr 2020, In: Diabetes. 69, 4, p. 614-623 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    GIP(3-30)NH2 – a tool for the study of GIP physiology

    Lynggaard, M. B., Gasbjerg, Lærke Smidt, Christensen, Mikkel Bring & Knop, Filip Krag, 2020, In: Current Opinion in Pharmacology. 55, p. 31-40 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  73. Published

    Bifidobacterium breve Bif195 ameliorates aspirin-induced gastric mucosal damage: A randomised, double blind, placebo-controlled crossover trial

    Løn, N., Engel, S., Damholt, A., Mortensen, B., Haaber, A. B., Wellejus, A. & Knop, Filip Krag, 2024, In: Alimentary Pharmacology and Therapeutics. 59, 3, p. 341-349 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Editorial: The microbiome and gastric mucosal protection in aspirin users—Authors' reply

    Løn, N., Engel, S., Damholt, A., Wellejus, A. & Knop, Filip Krag, 2024, In: Alimentary Pharmacology and Therapeutics. 59, 4, p. 577-578 2 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  75. Published

    Letter: Bif195 for aspirin-induced gastric mucosal damage – More to do in further research. Authors' reply

    Løn, N., Engel, S., Damholt, A., Wellejus, A. & Knop, Filip Krag, 2024, In: Alimentary Pharmacology and Therapeutics. 59, 10, p. 1306-1307 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  76. Published

    Individual and combined glucose-lowering effects of glucagon receptor antagonism and dipeptidyl peptidase-4 inhibition

    Maagensen, H., Haedersdal, S., Lund, A., Nielsen-Hannerup, E., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Diabetologia. 61, p. S246-S247

    Research output: Contribution to journalConference abstract in journalResearch

  77. Published

    Bone Turnover Markers in Patients With Nonalcoholic Fatty Liver Disease and/or Type 2 Diabetes During Oral Glucose and Isoglycemic Intravenous Glucose

    Maagensen, H., Junker, A. E., Jorgensen, N. R., Gluud, Lise Lotte, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Journal of Clinical Endocrinology & Metabolism. 103, 5, p. 2042-2049 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    The Gut-Bone Axis in Diabetes

    Maagensen, H., Helsted, M. M., Gasbjerg, Lærke Smidt, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: Current Osteoporosis Reports. 21, p. 21–31 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  79. Published

    Does glucose lowering restore GIP's effect on insulin secretion?

    Madsbad, Sten, Knop, Filip Krag & Holst, Jens Juul, 2023, In: Nutrition, Metabolism & Cardiovascular Diseases. 33, 9, p. 1817-1818

    Research output: Contribution to journalComment/debateResearch

  80. Published

    Characterization of Postprandial Bile Acid Profiles and Glucose Metabolism in Cerebrotendinous Xanthomatosis

    Majait, S., Meessen, E. C. E., Vaz, F. M., Kemper, E. M., Nierop, S. V., Olde Damink, S. W., Schaap, F. G., Romijn, J. A., Nieuwdorp, M., Verrips, A., Knop, Filip Krag & Soeters, M. R., 2023, In: Nutrients. 15, 21, 12 p., 4625.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Incretin hormones in patients with type 2 diabetes are increased by diet-oil, a pro-drug for the GPR 119 receptor agonist, 2-oleoyl-glycerol

    Mandoe, M. J., Hansen, K. B., Knop, Filip Krag, Holst, Jens Juul & Hansen, Harald S., Oct 2012, In: Diabetologia. 55, p. S340-S340

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  82. Published
  83. Published

    Mechanisms of the incretin effect in subjects with normal glucose tolerance and patients with type 2 diabetes

    Mari, A., Bagger, J. I., Ferrannini, E., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 2013, In: PLOS ONE. 8, 9, p. e73154

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Amylin and Calcitonin: Potential Therapeutic Strategies to Reduce Body Weight and Liver Fat

    Mathiesen, D. S., Lund, A., Vilsbøll, Tina, Knop, Filip Krag & Bagger, J. I., 2021, In: Frontiers in Endocrinology. 11, 617400.

    Research output: Contribution to journalReviewResearchpeer-review

  85. Published

    Long-acting amylin analogues for the management of obesity

    Mathiesen, D. S., Bagger, J. I. & Knop, Filip Krag, 2022, In: Current Opinion in Endocrinology, Diabetes and Obesity. 29, 2, p. 183-190 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    THERAPY OF ENDOCRINE DISEASE: Amylin and calcitonin - physiology and pharmacology

    Mathiesen, D. S., Lund, A., Holst, Jens Juul, Knop, Filip Krag, Lutz, T. A. & Bagger, J. I., 2022, In: European Journal of Endocrinology. 186, 6, p. R93-R111

    Research output: Contribution to journalReviewResearchpeer-review

  87. Published

    The effects of dual GLP-1/GIP receptor agonism on glucagon secretion: a review

    Mathiesen, D. S., Bagger, J. I., Bergmann, N. C., Lund, A., Christensen, Mikkel Bring, Vilsbøll, Tina & Knop, Filip Krag, 2019, In: International Journal of Molecular Sciences. 20, 17, 18 p., 4092.

    Research output: Contribution to journalReviewResearchpeer-review

  88. Published

    No detectable effect of a type 2 diabetes-associated TCF7L2 genotype on the incretin effect

    Mathiesen, D. S., Bagger, J., Hansen, K. B., Junker, A. E., Plamboeck, A., Harring, S., Idorn, T., Hornum, M., Holst, Jens Juul, Jonsson, Anna Elisabet, Hansen, Torben, Vilsbøll, Tina, Lund, Asger Bach & Knop, Filip Krag, 2020, In: Endocrine Connections. 9, 12, p. 1221-1232 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Accuracy of continuous glucose monitoring during exercise-related hypoglycemia in individuals with type 1 diabetes

    Maytham, K., Hagelqvist, P. G., Engberg, S., Forman, Julie Lyng, Pedersen-Bjergaard, Ulrik, Knop, Filip Krag, Vilsbøll, Tina & Andersen, A., 2024, In: Frontiers in Endocrinology. 15, 9 p., 1352829.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Predictors of Improvement in Quality of Life When Treating Hypothyroidism

    Medici, B. B., Lerche la Cour, J., Knop, Filip Krag, Krakauer, M., Michaelsson, L. F., Faber, Jens, Watt, Torquil & Nygaard, Birte, 2021, In: Journal of Thyroid Research. 2021, 7 p., 5577217.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Effects of levothyroxine substitution therapy on hunger and food intake in individuals with hypothyroidism

    Medici, B. R., Nygaard, Birte, la Cour, J. L., Krakauer, M., Brønden, Andreas, Sonne, M. P., Holst, Jens Juul, Rehfeld, Jens Frederik, Vilsbøll, Tina, Faber, J. & Knop, Filip Krag, 2023, In: Endocrine Connections. 12, 10, 14 p., e230314.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Parenteral nutrition impairs plasma bile acid and gut hormone responses to mixed meal testing in lean healthy men

    Meessen, E. C. E., Bakker, G. J., Nieuwdorp, M., Dallinga-Thie, G. M., Kemper, E. M., Olde Damink, S. W., Romijn, J. A., Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag, Groen, A. K., Schaap, F. G. & Soeters, M. R., 2021, In: Clinical Nutrition. 40, 3, p. 1013-1021

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Self-expanding metal stents for colonic obstruction: experiences from 104 procedures in a single center

    Meisner, S., Hensler, M., Knop, Filip Krag, West, F. & Wille-Jørgensen, P., 1 Apr 2004, In: Diseases of the Colon and Rectum. 47, 4, p. 444-50 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Rectal sensitivity correlated with gastrointestinal-mediated glucose disposal, but not the incretin effect

    Meling, S., Tjora, E., Eichele, H., Nedergaard, R. B., Knop, Filip Krag, Ejskjaer, N., Carlsen, S., Njølstad, P. R., Brock, C. & Søfteland, E., 2023, In: Endocrinology, Diabetes and Metabolism. 7, 1, 13 p., e463.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    High intensity interval training improves insulin sensitivity in individuals with prediabetes

    Mensberg, P., Frandsen, C., Espersen, E., Leineweber, T., Storgaard, H., Schlawitz, K. S., Petersen, T. H. D., Poulsen, J. N., Sørensen, F., Forman, Julie Lyng, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Diabetologia. 61, Supplement 1, p. S217-S218 2 p., 441.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  96. Published

    Near-normalization of glycaemic control with glucagon-like peptide-1 receptor agonist treatment combined with exercise in patients with type 2 diabetes

    Mensberg, P., Nyby, S., Jørgensen, P. G., Storgaard, H., Jensen, M. T., Sivertsen, J., Holst, Jens Juul, Kiens, Bente, Richter, Erik A., Knop, Filip Krag & Vilsbøll, Tina, 2017, In: Diabetes, Obesity and Metabolism. 19, 2, p. 172-180 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Effect of Antibiotics on Gut Microbiota, Gut Hormones and Glucose Metabolism

    Mikkelsen, K. H., Frost, M., Bahl, M. I., Licht, T. R., Jensen, U. S., Rosenberg, Jacob, Pedersen, Oluf Borbye, Hansen, Torben, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, 12 Nov 2015, In: PLOS ONE. 10, 11, p. 1-14 e0142352.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    No changes in levels of bone formation and resorption markers following a broad-spectrum antibiotic course

    Mikkelsen, K. H., Vilsbøll, Tina, Holst, Jens Juul, Hartmann, Bolette, Knop, Filip Krag & Frost, M., 2018, In: BMC Endocrine Disorders. 18, 6 p., 60.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Response to the letter: "epidemiologic association between antibiotic use with the risk of developing type 2 diabetes" by López-Hernández, D.

    Mikkelsen, K. H., Knop, Filip Krag, Frost, M., Hallas, J. & Pottegard, A., 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 11, 1 p., L121.

    Research output: Contribution to journalLetterResearchpeer-review

  100. Published

    Effect of antibiotics on gut microbiota, glucose metabolism and bodyweight regulation: a review of the literature

    Mikkelsen, K. H., Allin, K. H. & Knop, Filip Krag, May 2016, In: Diabetes, Obesity and Metabolism. 18, 5, 444–453.

    Research output: Contribution to journalReviewResearchpeer-review

ID: 40100368