Sten Madsbad
Clinical Professor
Department of Clinical Medicine
Kettegård Allé 30, 2650 Hvidovre
Member of:
Internal Medicine: Endocrinology
- 2008
- Published
Altered PI3-kinase/Akt signalling in skeletal muscle of young men with low birth weight
Jensen, C. B., Martin-Gronert, M. S., Storgaard, H., Madsbad, Sten, Vaag, Allan, Ozanne, S. E., Jensen, C. B., Martin-Gronert, M. S., Storgaard, H., Madsbad, Sten, Vaag, A. & Ozanne, S. E., 2008, In: PLoS ONE. 3, 11, p. e3738Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Beneficial effects of once-daily liraglutide, ahuman glucagon-like peptide-1 analogue, on cardiovascular risk biomarkers in patientswith Type 2 diabetes
Courreges, J., Vilsbøll, T., Zdravkovic, M., Le-Thi, T., Krarup, T., Schmitz, O., Verhoeven, R., Buganova, I. & Madsbad, Sten, 2008, In: Diabetic Medicine. 28, 9, p. 1129-1131Research output: Contribution to journal › Journal article › Research › peer-review
- Published
C-reactive protein, insulin resistance and risk of cardiovascular disease: a population-based study
Hansen, T. W., Olsen, M. H., Rasmussen, S., Ibsen, H., Torp-Pedersen, Christian, Hildebrandt, P. R., Madsbad, Sten, Jeppesen, J., Hansen, T. W., Olsen, M. H., Rasmussen, S., Ibsen, H., Torp-Pedersen, C., Hildebrandt, P. R. & Madsbad, Sten, 2008, In: European Journal of Cardiovascular Prevention & Rehabilitation. 15, 5, p. 594-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of tesofensine on bodyweight loss, body composition, and quality of life in obese patients: a randomised, double-blind, placebo-controlled trial
Astrup, A., Madsbad, Sten, Breum, Leif, Jensen, T. J., Kroustrup, J. P. & Larsen, T. M., 2008, In: Lancet. 372, 9653, p. 1906-1913 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of tesofensine on bodyweight loss, body composition, and quality of life in obese patients: a randomised, double-blind, placebo-controlled trial
Astrup, A., Madsbad, Sten, Breum, L., Jensen, T. J., Kroustrup, J. P. & Larsen, T. M., 2008, In: Lancet. 372, 9653, p. 1906-13 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes
Højberg, P. V., Vilsbøll, Tina, Rabøl, R., Knop, Filip Krag, Bache, M., Krarup, T., Holst, Jens Juul & Madsbad, Sten, 2008, In: Diabetologia. 52, 2, p. 199-207 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1: physiological effects and potential therapeutic applications
Aaboe, K., Krarup, T., Madsbad, Sten, Holst, Jens Juul, Aaboe, K., Krarup, T., Madsbad, Sten & Holst, J. J., 2008, In: Diabetic Medicine. 10, 11, p. 994-1003 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ghrelin agonist (TZP-101) accelerates gastric emptying independently of the presence of autonomic neuropathy in patiens with diabetic gastroparesis
Ejskjær, N., Hellström, P., Vestergaard, E. T., Madsbad, Sten, Madsen, J. L., Gormsen, L. C., Jensen, T. A., Pezzullo, J., Christensen, J. S., Shaughnessy, L. & Kotusic, G., 2008. 0 p.Research output: Contribution to conference › Paper › Research › peer-review
- Published
Glucagon-like peptide receptor agonists and dipeptidyl peptidase-4 inhibitors in the treatment of diabetes: a review of clinical trials
Madsbad, Sten, Krarup, T., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten, Krarup, T., Deacon, C. F. & Holst, J. J., 2008, In: Current Opinion in Clinical Nutrition and Metabolic Care. 11, 4, p. 491-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1, glucose homeostasis and diabetes.
Holst, Jens Juul, Deacon, Carolyn F., Vilsbøll, Tina, Krarup, T. & Madsbad, Sten, 2008, In: Trends in Molecular Medicine. 14, 4, p. 161-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human amylin, pramlintide and GLP-1: Influence on gastric emptying, appetite and food intake in humans
Asmar, M., Knop, F. K., Bache, M., Vilsboll, T., Madsbad, Sten & Holst, J. J., 2008, In: Diabetes. 57, Suppl. 1, p. A406-A407Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation
Sparsø, T., Andersen, G., Albrechtsen, Anders, Jørgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Wasson, J., Permutt, M. A., Glaser, B., Madsbad, Sten, Pedersen, Oluf Borbye & Hansen, Torben, 2008, In: Diabetologia. 51, 9, p. 1646-52 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes
Aaboe, K., Knop, Filip Krag, Vilsboll, T., Vølund, A., Simonsen, U., Deacon, Carolyn F., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2008, In: Journal of Clinical Endocrinology and Metabolism. 94, 2, p. 603-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Obesity, body composition and metabolic disturbances in polycystic ovary syndrome
Svendsen, P. F., Nilas, L., Nørgaard, Kirsten, Jensen, Jens-Erik Beck & Madsbad, Sten, 2008, In: Human Reproduction. 23, 9, p. 2113-21 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peripheral plasma C-peptide levels do not accuratly reflext prehepatic insulin secretion after intravenous glucose
Kielgast, U., Højbjerg, P., Zander, M., Storgaard, H., Madsen, J. L., Møller, Søren, Vølund, A. & Madsbad, Sten, 2008. 0 p.Research output: Contribution to conference › Poster › Research
- Published
Sex and muscle structural lipids in obese subjects - an impact on insulin action?
Haugaard, S. B., Vaag, Allan, Høy, C. & Madsbad, Sten, 2008, In: European Journal of Clinical Investigation. 38, 7, p. 494-501 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The proposed terminology 'A(1c)-derived average glucose' is inherently imprecise and should not be adopted. Reply to Bloomgarden ZT, Inzucchi SE, Karnieli E, et al. [letter]
Haugaard, S. B., Madsbad, Sten & Mølvig, J., 2008, In: Diabetologia. 52, 3, p. 547-49Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment of type 2 diabetes with incretin-based therapies
Madsbad, Sten, 2008, In: Lancet. 373, 9662, p. 438-9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liraglutide, a once-daily human GLP-1 analogue, improves pancreatic B-cell function and arginine-stimulated insulin secretion during hyperglycaemia in patients with Type 2 diabetes mellitus
Vilsbøll, Tina, Brock, B., Perrild, H., Levin, K., Lervang, H., Kølendorf, K. E., Krarup, T., Schmitz, O., Zdravkovic, M., Le Thi Thanh, X. & Madsbad, Sten, 1 Feb 2008, In: Diabetic Medicine. 25, 2, p. 152-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Near normalisation of blood glucose improves the potentiating effect of GLP-1 on glucose-induced insulin secretion in patients with type 2 diabetes
Højberg, P. V., Zander, M., Vilsbøll, T., Knop, Filip Krag, Krarup, T., Vølund, A., Holst, Jens Juul & Madsbad, Sten, 1 Apr 2008, In: Diabetologia. 51, 4, p. 632-640 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nye biologiske laegemidler til behandling af kroniske inflammatoriske sygdomme
Skov, Lone, Hegedüs, L., Madsbad, Sten & Bendtzen, K., 9 Jun 2008, In: Ugeskrift for Laeger. 170, 24, p. 2162Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide receptor agonists and dipeptidyl peptidase-4 inhibitors in the treatment of diabetes: a review of clinical trials
Madsbad, Sten, Krarup, T., Deacon, Carolyn F. & Holst, Jens Juul, Jul 2008, In: Current Opinion in Clinical Nutrition and Metabolic Care. 11, 4, p. 491-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patient-reported rating of gastrointestinal adverse effects during treatment of type 2 diabetes with the once-daily human GLP-1 analogue, liraglutide
Horowitz, M., Vilsbøll, Tina, Zdravkovic, M., Hammer, M. & Madsbad, Sten, 1 Jul 2008, In: Diabetes, Obesity and Metabolism. 10, 7, p. 593-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Beneficial effects of once-daily liraglutide, a human glucagon-like peptide-1 analogue, on cardiovascular risk biomarkers in patients with Type 2 diabetes
Courrèges, J., Vilsbøll, Tina, Zdravkovic, M., Le Thi Thanh, X., Krarup, T., Schmitz, O., Verhoeven, R., Bugáñová, I. & Madsbad, Sten, 1 Sep 2008, In: Diabetic Medicine. 25, 9, p. 1129-31 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Four weeks of near-normalization of blood glucose has no effect on postprandial GLP-1 and GIP secretion, but augments pancreatic B-cell responsiveness to a meal in patients with Type 2 diabetes
Højberg, P. V., Vilsbøll, T., Zander, M., Knop, Filip Krag, Krarup, T., Vølund, A., Holst, Jens Juul & Madsbad, Sten, Nov 2008, In: Diabetic Medicine Online. 25, 11, p. 1268-75 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1: physiological effects and potential therapeutic applications
Aaboe, K., Krarup, T., Madsbad, Sten & Holst, Jens Juul, Nov 2008, In: Diabetes, Obesity and Metabolism Online. 10, 11, p. 994-1003 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Four weeks of near-normalization of blood glucose has no effect on postprandial GLP-1 and GIP secretion, but augments pancreatic B-cell responsiveness to a meal in patients with Type 2 diabetes
Højberg, P. V., Vilsbøll, Tina, Zander, P. M., Knop, Filip Krag, Krarup, T., Vølund, A., Holst, J. M. & Madsbad, Sten, 1 Nov 2008, In: Diabetic Medicine. 25, 11, p. 1268-75 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene-gene interaction
Sparsø, T., Grarup, N., Andreasen, C., Albrechtsen, A., Holmkvist, J., Andersen, G., Jørgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Madsbad, S., Hansen, T., Pedersen, O., Sparsø, T., Grarup, N., Andreasen, C., Albrechtsen, A., Holmkvist, J., Andersen, G., Jørgensen, T. & 6 others, , 2009, In: Diabetologia. 52, 7, p. 1308-14 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Hyperglycemia on Mitochondrial Respiration in Type 2 Diabetes
Rabøl, R., Højberg, P. M. V., Almdal, Thomas Peter, Boushel, R., Haugaard, S. B., Madsbad, Sten, Dela, Flemming, Rabøl, R., Højberg, P. M. V., Almdal, T., Boushel, R., Haugaard, S. B., Madsbad, Sten & Dela, F., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 4, p. 1372-78Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effekt af tesofensine på kropsvægt og kropssammensætning hos svært overvægtige
Nielsen, A. H., Larsen, T. M., Madsbad, Sten, Breum, Leif, Jensen, T. J., Kroustrup, J. P. & Astrup, A., 2009, In: Ugeskrift for læger. 171, 41-42, p. 2974-2977 4 p.Research output: Contribution to journal › Journal article › Research
- Published
Exenatide and liraglutide: different approaches to develop GLP-1 receptor agonists (incretin mimetics)--preclinical and clinical results
Madsbad, Sten, 2009, In: Best Practice & Research: Clinical Endocrinology & Metabolism. 23, 4, p. 463-77 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of 11beta-hydroxysteroid dehydrogenase 1 and 2 in subcutaneous adipose tissue of lean and obese women with and without polycystic ovary syndrome
Svendsen, P. F., Madsbad, Sten, Nilas, L., Paulsen, S. K., Pedersen, S. B., Svendsen, P. F., Madsbad, Sten, Nilas, L., Paulsen, S. K. & Pedersen, S. B., 2009, In: International Journal of Obesity. 33, 11, p. 1249-56 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans
Sparsø, T., Bonnefond, A., Andersson, E., Bouatia-Naji, N., Holmkvist, J., Wegner, L., Grarup, N., Gjesing, A. P., Banasik, K., Cavalcanti-Proença, C., Marchand, M., Vaxillaire, M., Charpentier, G., Jarvelin, M-R., Tichet, J., Balkau, B., Marre, M., Lévy-Marchal, C., Faerch, K., Borch-Johnsen, K. & 36 others, , 2009, In: Diabetes. 58, 6, p. 1450-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ghrelin receptor agonist (TZP-101) accelerates gastric emptying in adults with diabetes and symptomatic gastroparesis
Ejskjaer, N., Vestergaard, E. T., Hellström, P. M., Gormsen, L. C., Madsbad, Sten, Madsen, J. L., Jensen, T. A., Pezzullo, J. C., Christiansen, J. S., Shaughnessy, L. & Kosutic, G., 2009, In: Alimentary Pharmacology and Therapeutics. 29, 11, p. 1179-87 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improved glycaemic control decreases inner mitochondrial membrane leak in type 2 diabetes
Rabøl, R., Højberg, P. M. V., Almdal, Thomas Peter, Boushel, R., Haugaard, S. B., Madsbad, Sten, Dela, Flemming, Rabøl, R., Højberg, P. M. V., Almdal, T., Boushel, R., Haugaard, S. B., Madsbad, Sten & Dela, F., 2009, In: Diabetic Medicine. 11, 4, p. 355-60 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin hormone secretion in women with polycystic ovary syndrome: roles of obesity, insulin sensitivity, and treatment with metformin
phk294, phk294, Nilas, L., Madsbad, Sten & Holst, Jens Juul, 2009, In: Metabolism - Clinical and Experimental. 58, 5, p. 586-593Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intramyocellular triglyceride content in man, influence of sex, obesity and glycaemic control
Haugaard, Steen Bendix, Madsbad, Sten, Mu, Huiling & Vaag, Allan, 2009, In: European Journal of Endocrinology. 161, 1, p. 57-64 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
K-ATP Channel Closure Ameliorates the Impaired Insulinotropic Effect of Glucose-Dependent Insulinotropic Polypeptide in Patients with Type 2 Diabetes
Aaboe, K., Knop, K., Vilsboll, T., Volund, A., Simonsen, U., Deacon, C. F., Madsbad, Sten, Holst, J. J. & Krarup, T., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 2, p. 603-608 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide (GIP) in patients with type 2 diabetes
Aaboe, K., Knop, Filip Krag, Vilsbøll, Tina, Vølund, A., Simonsen, U., Deacon, Carolyn F., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 2, p. 603-608Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kirurgisk behandling af type 2-diabetes
Olesen, S. C., Hansen, D. L., Almdal, Thomas Peter, Bendtsen, Flemming, Nordgaard, I., Hvolris, L. E., Holst, Jens Juul, Naver, L. & Madsbad, Sten, 2009, In: Ugeskrift for læger. 171, 8, p. 615-7 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liraglutide (Victoza) - the first once-daily human GLP-1 receptor analogue
Madsbad, Sten, 2009, In: Avances in Diabetologia. 25, p. 349-356 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liraglutide effect and action in diabetes (LEAD).
Madsbad, Sten, 2009, In: Expert Review of Endocrinology & Metabolism. 4, 2, p. 119-129 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial function in skeletal muscle in type 2 diabetes
Madsbad, Sten, 2009Research output: Book/Report › Ph.D. thesis › Research
- Published
Preserved inhibitory potency of GLP-1 on glucagon secretion in type 2 diabetes mellitus
Hare, K. J., Knop, Filip Krag, Asmar, M., Madsbad, Sten, Deacon, Carolyn F., Holst, Jens Juul & Vilsbøll, Tina, 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 12, p. 4679-87 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced skeletal muscle mitochondrial respiration and improved glucose metabolism in nondiabetic obese women during a very low calorie dietary intervention leading to rapid weight loss
Rabøl, R., Svendsen, P. F., Skovbro, M., Boushel, R., Haugaard, S. B., Schjerling, P., Schrauwen, P., Hesselink, M. K. C., Nilas, L., Madsbad, S., Dela, F., Rabøl, R., Svendsen, P. F., Skovbro, M., Boushel, R. C., Haugaard, S. B., Schjerling, P., Schrauwen, P., Hesselink, M. K. C., Nilas, L. & 2 others, , 2009, In: Metabolism - Clinical and Experimental. 58, 8, p. 1145-52 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Remission af type 2-diabetes efter gastric bypass-kirurgi: et medicinsk mysterium?
Jacobsen, S., Hansen, D. L., Worm, Dorte, Madsbad, Sten, Hvolris, L. E., Naver, L. P. S. & Holst, Jens Juul, 2009, In: Behandlerbladet. p. 20-29 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Skeletal muscle structural lipids improve during weight-maintenance after a very low calorie dietary intervention
Haugaard, Steen Bendix, Vaag, Allan, Mu, Huiling & Madsbad, Sten, 2009, In: Lipids in Health and Disease. 8, p. 34 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Study rationale and design of the CIMT trial: the Copenhagen Insulin and Metformin Therapy trial
Lundby Christensen, L., Almdal, T., Boesgaard, T., Breum, L., Dunn, E., Gade-Rasmussen, B., Gluud, C., Hedetoft, C., Jarloev, A., Jensen, T., Krarup, T., Johansen, L. B., Lund, S. S., Madsbad, S., Mathiesen, E., Moelvig, J., Nielsen, F., Perrild, H., Pedersen, O., Roeder, M. & 31 others, , 2009, In: Diabetes, Obesity and Metabolism. 11, 4, p. 315-22 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tesofensine and weight loss: author's reply
Astrup, A., Madsbad, Sten & Larsen, T. M., 2009, In: Lancet. 373, 9665, p. 720 1 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
The effect of tesofensine on weight loss: results from a one-armed, open-labelled extension study
Astrup, A., Madsbad, Sten, Breum, Leif, Kroustrup, J. P., Raben, A., Jensen, J. K. S., Meier, D. & Sjödin, Anders Mikael, 2009, In: Obesity Facts. suppl. 2, p. 211-212 2 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
The insulin-resistant phenotype of polycystic ovary syndrome
Svendsen, P. F., Madsbad, Sten & Nilas, L., 2009, In: Fertility and Sterility. 94, 3, p. 1052-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The long-term effect of tesofensine on weight loss: interim results from a one-armed, open-labelled extension study
Sjödin, Anders Mikael, Madsbad, Sten, Breum, Leif, Kroustrup, J. P., Raben, Anne, Jensen, J. K. S., Meier, D. & Astrup, A., 2009, In: Obesity. 17, Suppl. 2, p. S107 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
The prevalence of metabolic syndrome in Danish patients with HIV infection: the effect of antiretroviral therapy
Hansen, B. R., Petersen, J., Haugaard, Steen Bendix, Madsbad, Sten, Obel, Niels, Suzuki, Y., Andersen, O., Hansen, B. R., Petersen, J., Haugaard, S. B., Madsbad, Sten, Obel, N., Suzuki, Y. & Andersen, Ove, 2009, In: HIV Medicine. 10, 6, p. 378-87 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment of type 1 diabetic patients with glucagon-like peptide-1 (GLP-1) and GLP-1R agonists
Kielgast, U., Holst, J., Madsbad, Sten, Kielgast, U., Holst, J. J. & Madsbad, Sten, 2009, In: Current Diabetes Reviews. 5, 4, p. 266-75 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Twelve weeks treatment with the DPP-4 inhibitor sitagliptin improves glycaemic control, but does not improve GLP-1 secretion, in patients with type 2 diabetes - a randomised trial
Aaboe, K., Knop, F. K., Vilsbøll, Tina, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2009, In: Diabetologia. p. 748Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Tesofensine and weight loss - Authors' reply
Astrup, A., Madsbad, Sten & Larsen, T. M., 26 Feb 2009, In: Lancet. 373, 9665, p. 720 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men
Pilgaard, K., Jensen, C., Schou, J., Lyssenko, V., Wegner, L., Brøns, C., Vilsbøll, T., Hansen, T., Madsbad, S., Holst, J., Vølund, A., Poulsen, P., Groop, L., Pedersen, O., Vaag, A., Pilgaard, K., Jensen, C. B., Schou, J. H., Lyssenko, V., Wegner, L. & 10 others, , 1 Jul 2009, In: Diabetologia. 52, 7, p. 1298-307 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment of type 1 diabetic patients with glucagon-like peptide-1 (GLP-1) and GLP-1R agonists
Kielgast, U., Holst, Jens Juul & Madsbad, Sten, Nov 2009, In: Current Diabetes Reviews. 5, 4, p. 266-75 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin-based therapies: viewpoints on the way to consensus
Nauck, M. A., Vilsbøll, Tina, Gallwitz, B., Garber, A. & Madsbad, Sten, 1 Nov 2009, In: Diabetes Care. 32 Suppl 2, p. S223-31Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is Glycogen Synthase Kinase-3β an Ultraconserved Kernel Enzyme?
Fenger, M., Haugaard, S. B., Andersen, Ove, Madsbad, Sten, Werge, T. & Linneberg, A., 11 Dec 2009, In: Gene Expression to Genetical Genomics.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Adding liraglutide to oral antidiabetic drug therapy: onset of treatment effects over time
Gallwitz, B., Vaag, Allan, Falahati, A., Madsbad, Sten, Gallwitz, B., Vaag, A., Falahati, A. & Madsbad, Sten, 2010, In: International Journal of Clinical Practice. 64, 2, p. 267-76 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
At tro, at 50-60 årig ekan tabe sig, er naivt
Madsbad, Sten, 2010, Diabetes inspiration til almen praksis. Dagens Medicin, p. 14-21 7 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Desaturation of excess intramyocellular triacylglycerol in obesity: implications for glycemic control
Haugaard, Steen Bendix, Madsbad, Sten, Mu, Huiling & Vaag, Allan, 2010, In: International Journal of Obesity. 34, 3, p. 500-510 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of glucagon-like peptide-1 on alpha- and beta-cell function in C-peptide-negative type 1 diabetic patients
Kielgast, U., Asmar, M., Madsbad, Sten & Holst, Jens Juul, 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 5, p. 2492-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin resistance and glucose intolerance independently reduce the incretin effect via a beta cell defect
Jensen, D. H., Aaboe, K., Voelund, A., Henriksen, J. E., Holst, J. M., Madsbad, Sten & Krarup, T., 2010, In: Diabetologia. 53Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
New physiological effects of incretin hormones GLP-1 and GIP
Madsbad, Sten, 2010, Hvidovre Hospital. 56 p.Research output: Book/Report › Ph.D. thesis › Research
- Published
Non-insulin parenteral therapies
Madsbad, Sten, 2010, Textbook of Diabetes. Fourth Edition ed. Oxford, Vol. Volume 1. p. 215-235 20 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
On the role of glucose-dependent insulintropic polypeptide in postprandial metabolism in humans
Asmar, M., Tangaa, W., Madsbad, Sten, Hare, K., Astrup, A., Flint, A., Bülow, J. & Holst, Jens Juul, 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 298, 3, p. E614-21 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Opposite effects of pioglitazone and rosiglitazone on mitochondrial respiration in skeletal muscle of patients with type 2 diabetes
Rabøl, R., Boushel, R., Almdal, Thomas Peter, Hansen, C. N., Ploug, Thorkil, Haugaard, Steen Bendix, Prats Gavalda, Clara, Madsbad, Sten & Dela, Flemming, 2010, In: Diabetes, Obesity and Metabolism Online. 12, 9, p. 806-814 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pancreatic beta-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes
Asmar, M., Højberg, P. V., Deacon, Carolyn F., Hare, K., Holst, Jens Juul & Madsbad, Sten, 2010, In: Regulatory Peptides. 160, 1-3, p. 175-80 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pancreatic ß-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes
Asmar, M., Højberg, P., Deacon, Carolyn F., Hare, K., Holst, Jens Juul & Madsbad, Sten, 2010, In: Regulatory Peptides. 160, 1-3, p. 175-180 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial diabetic glucose tolerance is normalized by gastric bypass feeding as opposed to gastric feeding and is associated with exaggerated GLP-1 secretion: a case report
Dirksen, C., Hansen, D. L., Madsbad, Sten, Hvolris, L. E., Naver, L. S., Holst, Jens Juul & Worm, Dorte, 2010, In: Diabetes Care. 33, 2, p. 375-377Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sustained low-dose growth hormone therapy optimizes bioactive insulin-like growth factor-I level and may enhance CD4 T-cell number in HIV infection
Andersen, Ove, Hansen, B. R., Troensegaard, W., Flyvbjerg, A., Madsbad, Sten, Ørskov, H., Nielsen, J. O., Iversen, J. & Haugaard, S. B., 2010, In: Journal of Medical Virology. 82, 2, p. 197-205 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose- and non-glucose-induced insulin secretion in patients with type 2 diabetes mellitus
Aaboe, K., Knop, Filip Krag, Vilsbøll, Tina, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2010, In: Diabetes, Obesity and Metabolism. 12, 4, p. 323-333 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regional anatomic differences in skeletal muscle mitochondrial respiration in type 2 diabetes and obesity
Rabøl, R., Larsen, Steen, Højberg, P. M. V., Almdal, Thomas Peter, Boushel, R. C., Haugaard, Steen Bendix, Andersen, J. L., Madsbad, Sten & Dela, Flemming, 1 Feb 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 2, p. 857-63 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Desaturation of excess intramyocellular triacylglycerol in obesity: implications for glycemic control
Haugaard, S. B., Madsbad, Sten, Mu, H. & Vaag, A., 1 Mar 2010, In: International Journal of Obesity. 34, 3, p. 500-10 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Do the actions of glucagon-like peptide-1 on gastric emptying, appetite, and food intake involve release of amylin in humans?
Asmar, M., Bache, M., Knop, Filip Krag, Madsbad, Sten & Holst, Jens Juul, 1 May 2010, In: The Journal of clinical endocrinology and metabolism. 95, 5, p. 2367-75 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of association between LPIN1 variants and common metabolic phenotypes among 17,538 Danes
Burgdorf, K. S., Sandholt, C. H., Sparsø, T., Andersen, G., Witte, D. R., Jørgensen, T., Sandbaek, A., Lauritzen, T., Sørensen, Thorkild I.A., Madsbad, Sten, Hansen, Torben & Pedersen, Oluf Borbye, 1 Jul 2010, In: European Journal of Endocrinology. 163, 1, p. 81-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Measures of overweight and obesity and risk of cardiovascular disease: a population-based study
Sehestedt, T. B., Hansen, Tine Willum, Olsen, M. H., Abildstrøm, S. Z., Rasmussen, S., Ibsen, H., Torp-Pedersen, Christian, Madsbad, Sten, Jeppesen, J. & Jeppesen, J. L., 1 Aug 2010, In: European Journal of Cardiovascular Prevention & Rehabilitation. 17, 4, p. 486-90 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Relationship between common lipoprotein lipase gene sequence variants, hyperinsulinemia, and risk of ischemic heart disease: A population-based study
Jeppesen, J., Hansen, Tine Willum, Torp-Pedersen, Christian, Madsbad, Sten, Ibsen, H., Jørgensen, T. & Fenger, M., 1 Aug 2010, In: Atherosclerosis. 211, 2, p. 506-11 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-2, but not glucose-dependent insulinotropic polypeptide, stimulates glucagon release in patients with type 1 diabetes
Christensen, M., Knop, Filip Krag, Vilsbøll, Tina, Aaboe, K., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 9 Aug 2010, In: Regulatory Peptides. 163, 1-3, p. 96-101 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-dependent insulinotropic polypeptide may enhance fatty acid re-esterification in subcutaneous abdominal adipose tissue in lean humans
Asmar, M., Simonsen, L., Madsbad, Sten, Stallknecht, Bente Merete, Holst, Jens Juul & Bülow, J., 1 Sep 2010, In: Diabetes. 59, 9, p. 2160-3 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon suppression during OGTT worsens while suppression during IVGTT sustains alongside development of glucose intolerance in patients with chronic pancreatitis
Knop, Filip Krag, Vilsbøll, Tina, Larsen, S., Madsbad, Sten, Holst, Jens Juul & Krarup, T. M., 24 Sep 2010, In: Regulatory Peptides. 164, 2-3, p. 144-50 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Dyslipidemi
Madsbad, Sten, 2011, Diabetes - sygdom, behandling og organisation. Hilsted, J., Borch-Johnsen, K. & Christiansen, J. S. (eds.). Munksgaard , p. 201-314Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- Published
ERGEM: effects of roux-en-y gastric bypasss surgery on energy metabolism
Schmidt, J. B., Gregersen, N. T., Pedersen, S. D., Hansen, D. L., Worm, D., Madsbad, Sten, Astrup, A. & Sjödin, Anders Mikael, 2011, In: Obesity Reviews. 12, suppl. 1, p. 212 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Gastric bypass and duodenal and gastric feeding: a comment to Hansen et al
Jorgensen, N. B., Dirksen, C., Holst, Jens Juul & Madsbad, Sten, 2011, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 301, 5, p. G938-G9389 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetics of the ceramide/sphingosine-1-phosphate rheostat in blood pressure regulation and hypertension
Fenger, M., Linneberg, Allan René, Jørgensen, T., Madsbad, Sten, Søbye, K., Eugen-Olsen, J. & Jeppesen, J., 2011, In: B M C Genetics. 12, p. 44Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glykæmi og komplikationer
Christiansen, J. S. & Madsbad, Sten, 2011, Diabetes - sygdom, behandling og organisation. Hilsted, J., Borch-Johnsen, K. & Christiansen, J. S. (eds.). 2. udgave ed. Munksgaard , p. 189-198Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- Published
Homozygous carriers of the G allele of rs4664447 of the glucagon gene (GCG) are characterised by decreased fasting and stimulated levels of insulin, glucagon and glucagon-like peptide (GLP)-1
Torekov, S. S., Ma, L., Grarup, N., Hartmann, B., Hainerová, I. A., Kielgast, U., Kissow, H., Rosenkilde, M., Lebl, J., Witte, D. R., Jørgensen, T., Sandbaek, A., Lauritzen, T., Madsen, O. D., Wang, J., Linneberg, A., Madsbad, S., Holst, J. J., Hansen, T., Pedersen, O. & 1 others, , 2011, In: Diabetologia. 54, 11, p. 2820-31 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes
Larsen, Steen, Stride, N., Hey-Mogensen, M., Hansen, C. N., Andersen, J. L., Madsbad, Sten, Worm, Dorte, Helge, Jørn Wulff & Dela, Flemming, 2011, In: Diabetologia. 54, 6, p. 1427-36 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Langtidseffekt af vægtreducerende behandlinghos patienter med hypertension--en gennemgang af et Cochrane-review
Madsbad, Sten, 2011, In: Ugeskrift for Laeger. 173, 8, p. 564-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Obesity - an indication for GLP-1 treatment? Obesity pathophysiology and GLP-1 treatment potential
Torekov, Signe Sørensen, Madsbad, Sten & Holst, Jens Juul, 2011, In: Obesity Reviews. 12, 8, p. 593-601 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Retinal function in relation to improved glycaemic control in type 1 diabetes
Holfort, S. K., Nørgaard, Kirsten, Jackson, G., Hommel, E., Madsbad, Sten, Munch, I. C., Klemp, K., Sander, B. & Larsen, Michael, 2011, In: Diabetologia. 54, 7, p. 1853-61 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Skeletal Muscle Mitochondrial Function in Polycystic Ovarian Syndrome
Rabøl, R., Svendsen, P. M., Skovbro, M., Boushel, R. C., Schjerling, Peter, Nilas, L., Madsbad, Sten & Dela, Flemming, 2011, In: European Journal of Endocrinology. 165, 4, p. 631-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of the Association of Arg72Pro of Tumor Suppressor Protein p53 with Type 2 Diabetes in a Combined Analysis of 55,521 Europeans
Burgdorf, K. S., Grarup, Niels, Justesen, Johanne Marie, Harder, M. N., Witte, D. R., Jørgensen, T., Sandbæk, A., Lauritzen, T., Madsbad, Sten, Hansen, Torben, DIAGRAM Consortium, D. C. & Pedersen, Oluf Borbye, 2011, In: P L o S One. 6, 1, p. e15813 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ætiologi og patogenese, type 2 diabetes
Madsbad, Sten, 2011, Diabetes - sygdom, behandling og organisation. Hilsted, J., Borch-Johansen, K. & Christiansen, J. S. (eds.). Munksgaard , p. 97-107Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- Published
An overview of once-weekly glucagon-like peptide-1 receptor agonists--available efficacy and safety data and perspectives for the future
Madsbad, Sten, Kielgast, U., Asmar, M., Deacon, Carolyn F., Torekov, Signe Sørensen & Holst, Jens Juul, May 2011, In: Diabetes, Obesity and Metabolism. 13, 5, p. 394-407 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antidiabetic actions of endogenous and exogenous GLP-1 in type 1 diabetic patients with and without residual ß-cell function
Kielgast, U., Holst, Jens Juul & Madsbad, Sten, May 2011, In: Diabetes. 60, 5, p. 1599-1607 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss of Incretin Effect Is a Specific, Important, and Early Characteristic of Type 2 Diabetes
Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina, Krarup, T. & Madsbad, Sten, May 2011, In: Diabetes Care. 34, Supplement 2, p. S251-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Four weeks of treatment with liraglutide reduces insulin dose without loss of glycemic control in type 1 diabetic patients with and without residual beta-cell function
Kielgast, U., Krarup, T., Holst, Jens Juul, Madsbad, Sten & Krarup, T., Jul 2011, In: Diabetes Care. 34, 7, p. 1463-1468 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 10877
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Instrumentalization of eating improves weight loss maintenance in obesity
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Treatment with liraglutide may improve markers of CVD reflected by reduced levels of apoB
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Roux-en-Y gastric bypass surgery of morbidly obese patients induces swift and persistent changes of the individual gut microbiota
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