Filip Krag Knop

Filip Krag Knop

Clinical Professor

Member of:

  • Internal Medicine: Endocrinology


  1. 2017
  2. Published

    Is double-blinding achievable in a placebo-controlled trial with the glucagon-like-peptide-1 receptor agonist liraglutide?

    Foghsgaard, S., Vedtofte, L., Bahne, E., Andreasen, C., Christiansen, L. K., Svare, J. A., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Gluud, Lise Lotte, Knop, Filip Krag & Vilsbøll, Tina, 2017, In: Diabetologia. 60, S1, p. S369-S369

    Research output: Contribution to journalConference abstract in journalResearch

  3. Published

    Metformin potentiates bile acid-induced GLP-1 secretion in patients with type 2 diabetes

    Bronden, A., Alber, A., Rohde, U., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Diabetologia. 60, p. 113-113 242.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  4. Published

    Near-normalization of glycaemic control with glucagon-like peptide-1 receptor agonist treatment combined with exercise in patients with type 2 diabetes

    Mensberg, P., Nyby, S., Jørgensen, P. G., Storgaard, H., Jensen, M. T., Sivertsen, J., Holst, Jens Juul, Kiens, Bente, Richter, Erik A., Knop, Filip Krag & Vilsbøll, Tina, 2017, In: Diabetes, Obesity and Metabolism. 19, 2, p. 172-180 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Short-acting glucagon-like peptide-1 receptor agonists as add-on to insulin therapy in type 1 diabetes: A review

    Albèr, A., Brønden, A. & Knop, Filip Krag, 2017, In: Diabetes, Obesity and Metabolism. 19, 7, p. 915-925

    Research output: Contribution to journalReviewResearchpeer-review

  6. Published

    Supportive and non-supportive interactions in families with a type 2 diabetes patient: an integrative review

    Bennich, B. B., Røder, M. E., Overgaard, D., Egerod, Ingrid Eugenie, Munch, L., Knop, Filip Krag, Vilsbøll, Tina & Konradsen, H., 2017, In: Diabetology & Metabolic Syndrome. 9, 10 p., 57.

    Research output: Contribution to journalReviewResearchpeer-review

  7. Published

    THERAPY Liraglutide: preventing or postponing T2DM diagnosis?

    Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Nature Reviews Endocrinology. 13, p. 320-322

    Research output: Contribution to journalComment/debateResearchpeer-review

  8. Published

    Weight loss for overweight and obese individuals with gout: a systematic review of longitudinal studies

    Nielsen, S. M., Bartels, E. M., Henriksen, Marius, Wæhrens, E. E., Gudbergsen, Henrik Rindel, Bliddal, Henning, Astrup, A., Knop, Filip Krag, Carmona, L., Taylor, W. J., Singh, J. A., Perez-Ruiz, F., Kristensen, L. E. & Christensen, R., 2017, In: Annals of the Rheumatic Diseases. 76, 11, p. 1870-1882 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Nonalcoholic Fatty Liver Disease Is Prevalent in Women With Prior Gestational Diabetes Mellitus and Independently Associated With Insulin Resistance and Waist Circumference

    Foghsgaard, S., Andreasen, C., Vedtofte, L., Andersen, E. S., Bahne, E., Strandberg, C., Buhl, T., Holst, Jens Juul, Svare, J. A., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Gluud, Lise Lotte, Knop, Filip Krag & Vilsbøll, Tina, Jan 2017, In: Diabetes Care. 40, 1, p. 109-116 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Effect of GLP-1 Receptor Agonist Treatment on Body weight in Obese Antipsychotic-treated Patients with Schizophrenia: a Randomized, Placebo-controlled Trial Byline

    Ishøy, P. L., Knop, Filip Krag, Broberg, B. V., Bak, N., Andersen, U. B., Jørgensen, N. R., Holst, Jens Juul, Glenthøj, Birte Yding & Ebdrup, Bjørn, Feb 2017, In: Diabetes, Obesity and Metabolism. 19, 2, p. 162-171

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Glucagon and Amino Acids Are Linked in a Mutual Feedback Cycle: The Liver-α-Cell Axis

    Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens & Knop, Filip Krag, Feb 2017, In: Diabetes. 66, 2, p. 235-240 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    The impact of EndoBarrier gastrointestinal liner in obese patients with normal glucose tolerance and in patients with type 2 diabetes

    Rohde, U., Federspiel, C. A., Vilmann, Peter, Langholz, Ebbe, Friis, S. U., Krakauer, M., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Feb 2017, In: Diabetes, Obesity and Metabolism. 19, 2, p. 189-199 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Use of antibiotics in childhood and risk of Type 1 diabetes: a population-based case-control study

    Mikkelsen, K. H., Knop, Filip Krag, Vilsbøll, Tina, Frost, M., Hallas, J. & Pottegård, A., Feb 2017, In: Diabetic Medicine. 34, 2, p. 272–277

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Adult atopic dermatitis and the risk of type 2 diabetes

    Andersen, Y. M. F., Egeberg, A., Gislason, Gunnar Hilmar, Skov, Lone, Knop, Filip Krag & Thyssen, Jacob Pontoppidan, Mar 2017, In: The Journal of allergy and clinical immunology. 139, 3, p. 1057-1059 3 p.

    Research output: Contribution to journalLetterResearchpeer-review

  15. Published

    Clinical relevance of the bile acid receptor TGR5 in metabolism

    van Nierop, F. S., Scheltema, M. J., Eggink, H. M., Pols, T. W., Sonne, David Peick, Knop, Filip Krag & Soeters, M. R., Mar 2017, In: The Lancet Diabetes and Endocrinology. 5, 3, p. 224–233

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    Efficacy and safety of fixed-ratio combination of insulin degludec and liraglutide (IDegLira) for the treatment of type 2 diabetes

    Vedtofte, L., Knop, Filip Krag & Vilsbøll, Tina, Mar 2017, In: Expert Opinion on Drug Safety. 16, 3, p. 387-396 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  17. Published

    Bile acid sequestrants for glycemic control in patients with type 2 diabetes: A systematic review with meta-analysis of randomized controlled trials

    Hansen, M., Sonne, David Peick, Mikkelsen, K. H., Gluud, Lise Lotte, Vilsbøll, Tina & Knop, Filip Krag, May 2017, In: Journal of Diabetes and its Complications. 31, 5, p. 918-927 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Effects of liraglutide on cardiovascular risk factors in patients with type 1 diabetes

    Dejgaard, T. F., Johansen, N. B., Frandsen, C. S. S., Asmar, A., Tarnow, L., Knop, Filip Krag, Madsbad, Sten & Andersen, H. U., May 2017, In: Diabetes, Obesity and Metabolism. 19, 5, p. 734–738

    Research output: Contribution to journalLetterResearchpeer-review

  19. Published

    Postprandial Plasma Concentrations of ProANP in Patients with Type 2 Diabetes and Healthy Controls

    Sonne, D. P., Terzic, D., Knop, Filip Krag & Goetze, Jens P. , May 2017, In: Clinical Chemistry. 63, 5, p. 1040-1041 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  20. Published

    The effect of empagliflozin on oxidative nucleic acid modifications in patients with type 2 diabetes: Protocol for a randomised, double-blinded, placebo-controlled trial

    Larsen, E. L., Cejvanovic, V., Kjær, L. K., Vilsbøll, Tina, Knop, Filip Krag, Rungby, Jørgen & Poulsen, Henrik Enghusen, May 2017, In: BMJ Open. 7, 5, 6 p., e014728.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Glucagon-like peptide-1 receptor agonists and risk of acute pancreatitis in patients with type 2 diabetes

    Storgaard, H., Cold, F., Gluud, Lise Lotte, Vilsbøll, Tina & Knop, Filip Krag, Jun 2017, In: Diabetes, Obesity and Metabolism. 19, 6, p. 906-908

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    No cognitive-enhancing effect of GLP-1 receptor agonism in antipsychotic-treated, obese patients with schizophrenia

    Ishøy, P. L., Fagerlund, Birgitte, Broberg, B. V., Bak, N., Knop, Filip Krag, Glenthøj, Birte Yding & Ebdrup, Bjørn, Jul 2017, In: Acta Psychiatrica Scandinavica. 136, 1, p. 52-62

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Women with prior gestational diabetes mellitus and prediabetes are characterised by a decreased incretin effect

    Foghsgaard, S., Vedtofte, L., Andreasen, C., Andersen, E. S., Bahne, E., Bagger, J. I., Svare, J. A., Holst, Jens Juul, Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Knop, Filip Krag & Vilsbøll, Tina, Jul 2017, In: Diabetologia. 60, 7, p. 1344-1353 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    The Gut: A Key to the Pathogenesis of Type 2 Diabetes?

    Holst, Jens Juul, Pedersen, Jens, Albrechtsen, Nicolai Jacob Wewer & Knop, Filip Krag, Aug 2017, In: Metabolic Syndrome and Related Disorders. 15, 6, p. 259-262 4 p.

    Research output: Contribution to journalReviewResearchpeer-review

  25. Published

    Evidence connecting old, new and neglected glucose-lowering drugs to bile acid-induced GLP-1 secretion: a review

    Kårhus, M. L., Brønden, A., Sonne, D. P., Vilsbøll, Tina & Knop, Filip Krag, Sep 2017, In: Diabetes, Obesity and Metabolism. 19, 9, p. 1214-1222

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    A sandwich ELISA for measurement of the primary glucagon-like peptide-1 metabolite

    Albrechtsen, Nicolai Jacob Wewer, Asmar, A., Jensen, F., Törang, S., Simonsen, L., Kuhre, Rune Ehrenreich, Asmar, M., Veedfald, Simon, Plamboeck, A., Knop, Filip Krag, Vilsbøll, Tina, Madsbad, Sten, Nauck, M. A., Deacon, Carolyn F., Bülow, J., Holst, Jens Juul & Hartmann, Bolette, 1 Sep 2017, In: American Journal of Physiology: Endocrinology and Metabolism. 313, 3, p. E284-E291

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Improvement of Insulin Sensitivity after Lean Donor Feces in Metabolic Syndrome Is Driven by Baseline Intestinal Microbiota Composition

    Kootte, R. S., Levin, E., Salojärvi, J., Smits, L. P., Hartstra, A. V., Udayappan, S. D., Hermes, G., Bouter, K. E., Koopen, A. M., Holst, J. J., Knop, F. K., Blaak, E. E., Zhao, J., Smidt, H., Harms, A. C., Hankemeijer, T., Bergman, J. J. G. H. M., Romijn, H. A., Schaap, F. G., Olde Damink, S. W. M. & 8 others, Ackermans, M. T., Dallinga-Thie, G. M., Zoetendal, E., de Vos, W. M., Serlie, M. J., Stroes, E. S. G., Groen, A. K. & Nieuwdorp, M., Oct 2017, In: Cell Metabolism. 26, 4, p. 611-619.e6 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Mathematical Modelling of Glucose-Dependent Insulinotropic Polypeptide and Glucagon-like Peptide-1 following Ingestion of Glucose

    Røge, R. M., Bagger, J. I., Alskär, O., Kristensen, N. R., Klim, S., Holst, Jens Juul, Ingwersen, S. H., Karlsson, M. O., Knop, Filip Krag, Vilsbøll, Tina & Kjellsson, M. C., Oct 2017, In: Basic & Clinical Pharmacology & Toxicology. 121, 4, p. 290-297 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    'No cognitive-enhancing effect of GLP-1 receptor agonism in antipsychotic-treated, obese patients with schizophrenia': authors' response

    Ebdrup, Bjørn, Ishøy, P. L., Fagerlund, Birgitte, Broberg, B. V., Bak, N., Knop, Filip Krag & Glenthøj, Birte Yding, Nov 2017, In: Acta Psychiatrica Scandinavica. 136, 5, p. 526-527

    Research output: Contribution to journalComment/debateResearch

  30. Published

    Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production

    Albrechtsen, N. J. W., Kuhre, R. E., Hornburg, D., Jensen, C. Z., Hornum, M., Dirksen, C., Svane, M., Gasbjerg, L. S., Jorgensen, N. B., Gabe, M. N., Balk-Moller, E., Albrechtsen, R., Winther-Sorensen, M., Galsgaard, K. D., Meissner, F., Jorsal, T., Lund, A., Vilsboll, T., Eliasen, R., Bojsen-Moller, K. N. & 9 others, Idorn, T., Deacon, Carolyn F., Knop, Filip Krag, Rosenkilde, Mette, Hartmann, Bolette, Feldt-Rasmussen, Bo, Mann, Matthias, Madsbad, Sten & Holst, Jens Juul, Nov 2017, In: Cell Reports. 21, 6, p. 1452-1460

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Single-Dose Metformin Enhances Bile Acid-Induced Glucagon-Like Peptide-1 Secretion in Patients With Type 2 Diabetes

    Brønden, A., Albér, A., Rohde, U., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Nov 2017, In: The Journal of clinical endocrinology and metabolism. 102, 11, p. 4153-4162 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Impaired beta cell sensitivity to incretins in type 2 diabetes is insufficiently compensated by higher incretin response

    Tura, A., Bagger, J. I., Ferrannini, E., Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina & Mari, A., Dec 2017, In: Nutrition, Metabolism and Cardiovascular Diseases. 27, 12, p. 1123-1129 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Julefrokostdilemmaet

    Lanng, A. R., Gasbjerg, L. S. & Knop, Filip Krag, 11 Dec 2017, In: Ugeskrift for Laeger. 179, 25, p. 2212-15 4 p., V69590.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. 2018
  35. Published

    A gut feeling about glucagon: Eje Prize 2018

    Knop, Filip Krag, 2018, In: European Journal of Endocrinology. 178, 6, p. R267-R280 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  36. Published

    Bone Turnover Markers in Patients With Nonalcoholic Fatty Liver Disease and/or Type 2 Diabetes During Oral Glucose and Isoglycemic Intravenous Glucose

    Maagensen, H., Junker, A. E., Jorgensen, N. R., Gluud, Lise Lotte, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Journal of Clinical Endocrinology & Metabolism. 103, 5, p. 2042-2049 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Cardiovascular biomarkers in clinical studies of type 2 diabetes

    Baldassarre, M. P. A., Andersen, A., Consoli, A., Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Diabetes, Obesity and Metabolism. 20, 6, p. 1350-1360

    Research output: Contribution to journalReviewResearchpeer-review

  38. Published

    Changes in oxidative RNA and DNA modifications following one-week treatment with sevelamer: two randomized, placebo-controlled trials

    Larsen, E. L., Brønden, A., Karstoft, K., Henriksen, T., Vilsbøll, Tina, Poulsen, Henrik Enghusen & Knop, Filip Krag, 2018, In: Free Radical Biology and Medicine. 128, p. S118 280.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  39. Published

    Changes in urinary excretion of oxidative nucleic acid modifications in the week following Copenhagen Marathon 2018, Denmark

    Larsen, E. L., Kjær, L. K., Michaelsen, C., Andersen, E., Lyngbæk, M., Petersen-bønding, C., Henriksen, T., Vilsbøll, Tina, Knop, Filip Krag, Ploug, Thorkil, Poulsen, Henrik Enghusen & Karstoft, K., 2018, In: Free Radical Biology and Medicine. 128, S1, p. S54

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  40. Published

    Cholecystokinin secretion is suppressed by glucagon-like peptide-1: clue to the mechanism of the adverse gallbladder events of GLP-1-derived drugs

    Rehfeld, Jens Frederik, Knop, Filip Krag, Asmar, A., Madsbad, Sten, Holst, Jens Juul & Asmar, M., 2018, In: Scandinavian Journal of Gastroenterology. 53, 12, p. 1429-1432

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published
  42. Published

    Diagnostik og behandling af maturity onset diabetes of the young type 3

    Rose, K., Christensen, A. S., Storgaard, H., Hædersdal, S., Hansen, Torben, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Ugeskrift for Laeger. 180, 6 p., V06170502.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Differences Between Randomized Clinical Trial Patients and Real-World Initiators of the Glucagon-Like Peptide 1 Receptor Agonist Liraglutide

    Knudsen, J. S., Thomsen, R. W., Pottegård, A., Knop, Filip Krag & Sørensen, H. T., 2018, In: Diabetes Care. 41, 9, p. e133-e135 3 p.

    Research output: Contribution to journalLetterResearchpeer-review

  44. Published

    Diverse hepatic microbial DNA fingerprints in healthy lean and obese steatotic humans

    Bagger, J. I., Suppli, M. P., Nielsen, T., Lelouvier, B., Broha, A., Demant, M., Konig, M. J., Strandberg, C., Lund, A., Vilsbøll, Tina & Knop, Filip Krag, 2018, In: Diabetologia. 61, p. S120-S121

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  45. Published

    Duodenal L cell density correlates with features of metabolic syndrome and plasma metabolites

    Van Baar, A. C. G., Prodan, A., Wahlgren, C. D., Poulsen, Steen Seier, Knop, Filip Krag, Groen, A. K., Bergman, J. J., Nieuwdorp, M. & Levin, E., 2018, In: Endocrine Connections. 7, 5, p. 673-680

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Effects of liraglutide on gallbladder emptying: A randomized, placebo-controlled trial in adults with overweight or obesity

    Nexoe-Larsen, C. C., Sorensen, P. H., Hausner, H., Agersnap, M., Baekdal, M., Bronden, A., Gustafsson, L. N., Sonne, David Peick, Vedtofte, L., Vilsbøll, Tina & Knop, Filip Krag, 2018, In: Diabetes, Obesity and Metabolism. 20, 11, p. 2557-2564

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Evidence of a liver-alpha cell axis in humans: hepatic insulin resistance attenuates relationship between fasting plasma glucagon and glucagonotropic amino acids

    Albrechtsen, Nicolai Jacob Wewer, Færch, K., Jensen, T. M., Witte, D. R., Pedersen, Jens, Mahendran, Y., Jonsson, Anna Elisabet, Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Torekov, Signe Sørensen, Lauritzen, T., Pedersen, Oluf Borbye, Knop, Filip Krag, Hansen, Torben, Jørgensen, M. E., Vistisen, D. & Holst, Jens Juul, 2018, In: Diabetologia. 61, 3, p. 671-680

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    FGF21, a liver hormone that inhibits alcohol intake in mice, increases in human circulation after acute alcohol ingestion and sustained binge drinking at Oktoberfest

    Søberg, S., Andersen, E. S., Dalsgaard, N. B., Jarlhelt, I., Hansen, N. L., Hoffmann, N., Vilsbøll, Tina, Chenchar, A., Jensen, M., Grevengoed, Trisha Jean, Trammell, Sam, Knop, Filip Krag & Gillum, M. P., 2018, In: Molecular Metabolism. 11, p. 96-103 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Future Perspectives on GLP-1 Receptor Agonists and GLP-1/glucagon Receptor Co-agonists in the Treatment of NAFLD

    Seghieri, M., Christensen, A. S., Andersen, A., Solini, A., Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Frontiers in Endocrinology. 9, p. 1-10 649.

    Research output: Contribution to journalReviewResearchpeer-review

  50. Published

    Glimepiride monotherapy versus combination of glimepiride and linagliptin therapy in patients with HNF1A-diabetes: a protocol for a randomised, double-blinded, placebo-controlled trial

    Christensen, A. S., Storgaard, H., Hædersdal, S., Hansen, Torben, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: BMJ Open. 8, p. 1-9 e022517.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Glucagon-like peptide 1 in health and disease

    Andersen, A., Lund, A., Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Nature Reviews Endocrinology. 14, p. 390-403

    Research output: Contribution to journalReviewResearchpeer-review

  52. Published

    Hemodynamic Effects of Glucagon: A Literature Review

    Petersen, K. M., Bogevig, S., Holst, Jens Juul, Knop, Filip Krag & Christensen, Mikkel Bring, 2018, In: Journal of Clinical Endocrinology & Metabolism. 103, 5, p. 1804-1812

    Research output: Contribution to journalReviewResearchpeer-review

  53. Published

    High intensity interval training improves insulin sensitivity in individuals with prediabetes

    Mensberg, P., Frandsen, C., Espersen, E., Leineweber, T., Storgaard, H., Schlawitz, K. S., Petersen, T. H. D., Poulsen, J. N., Sørensen, F., Forman, Julie Lyng, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Diabetologia. 61, Supplement 1, p. S217-S218 2 p., 441.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  54. Published

    Hyperglucagonemia correlates with plasma levels of non-branched-chain amino acids in patients with liver disease independent of type 2 diabetes

    Albrechtsen, Nicolai Jacob Wewer, Junker, A. E., Christensen, M., Hædersdal, S., Wibrand, F., Lund, A. M., Galsgaard, Katrine Douglas, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 314, 1, p. G91-G96

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Individual and combined glucose-lowering effects of glucagon receptor antagonism and dipeptidyl peptidase-4 inhibition

    Maagensen, H., Haedersdal, S., Lund, A., Nielsen-Hannerup, E., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Diabetologia. 61, p. S246-S247

    Research output: Contribution to journalConference abstract in journalResearch

  56. Published

    Individual and combined glucose-lowering effects of glucagon receptor antagonism and sodium-glucose cotransporter 2 inhibition

    Haedersdal, S., Lund, A., Maagensen, H., Nielsen-Hannerup, E., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2018, p. S312-S312.

    Research output: Contribution to conferencePosterResearch

  57. Published

    Management of Patients with Type 2 Diabetes Shared between a Specialized Outpatient Clinic and General Practice Was Noninferior to Mono Management in a Specialized Outpatient Clinic—A Prospective, Randomized, Noninferiority Trial

    Munch, L., Bennich, B. B., Overgaard, D., Konradsen, Hanne, Middelfart, H. V., Kaarsberg, N., Knop, Filip Krag, Vilsbøll, Tina & Røder, M., 2018, In: Diabetes. 67, Supplement 1, 6-OR.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  58. Published

    Metformin er en mulig glukagonlignende peptid-1-stimulator

    Bahne, E., Brønden, A., Vilsbøll, Tina & Knop, Filip Krag, 2018, In: Ugeskrift for Laeger. 180, 12, 4 p., V07170516.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Metformin-induced glucagon-like peptide-1 secretion contributes to the actions of metformin in type 2 diabetes

    Bahne, E., Sun, E. W. L., Young, R. L., Hansen, M., Sonne, D. P., Hansen, J. S., Rohde, U., Liou, A. P., Jackson, M. L., de Fontgalland, D., Rabbitt, P., Hollington, P., Sposato, L., Due, S., Wattchow, D. A., Rehfeld, Jens Frederik, Holst, Jens Juul, Keating, D. J., Vilsbøll, Tina & Knop, Filip Krag, 2018, In: JCI Insight. 3, 23, p. 1-16 e93936.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Model-Based Prediction of Plasma Concentration and Enterohepatic Circulation of Total Bile Acids in Humans

    Guiastrennec, B., Sonne, David Peick, Bergstrand, M., Vilsbøll, Tina, Knop, Filip Krag & Karlsson, M. O., 2018, In: C P T: Pharmacometrics & Systems Pharmacology. 7, 9, p. 603-612

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Mono- and co-activation of the GIP and GLP-1 receptors inhibits bone resorption

    Bergmann, N. C., Lund, A., Heimburger, S. M., Gasbjerg, Lærke Smidt, Jørgensen, Niklas Rye, Jessen, L., Hartmann, Bolette, Holst, Jens Juul, Christensen, Mikkel Bring, Vilsbøll, Tina & Knop, Filip Krag, 2018, In: Diabetologia. 61, S.1, p. S348-S348 717.

    Research output: Contribution to journalConference abstract in journalResearch

  62. Published

    No changes in levels of bone formation and resorption markers following a broad-spectrum antibiotic course

    Mikkelsen, K. H., Vilsbøll, Tina, Holst, Jens Juul, Hartmann, Bolette, Knop, Filip Krag & Frost, M., 2018, In: BMC Endocrine Disorders. 18, 6 p., 60.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Postprandial effects of individual and combined GIP and GLP-1 receptor antagonism in healthy subjects

    Gasbjerg, Lærke Smidt, Helsted, M. M., wbf943, wbf943, Lanng, A. R., Stensen, S., Jakobsen, M. H., Hartmann, Bolette, Christensen, Mikkel Bring, Holst, Jens Juul, Vilsbøll, Tina, Rosenkilde, M. M. & Knop, Filip Krag, 2018, In: Diabetologia. 61, S1, p. S246-S246 503.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  64. Published

    Preclinical discovery and development of colesevelam for the treatment of type 2 diabetes

    Nerild, H. H., Christensen, Mikkel Bring, Knop, Filip Krag & Brønden, A., 2018, In: Expert Opinion on Drug Discovery. 13, 12, p. 1161-1167 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Protocol for Meal-time Administration of Exenatide for Glycaemic Control in Type 1 Diabetes Cases (The MAG1C trial): A randomised, double-blinded, placebo-controlled trial

    Johansen, N. J., Dejgaard, T. F., Lund, A., Vilsbøll, Tina, Andersen, H. U. & Knop, Filip Krag, 2018, In: BMJ Open. 8, 6, 8 p., 021861.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Response to Letter to the Editor: "Hemodynamic Effects of Glucagon: A Literature Review"

    Petersen, K. M., Bøgevig, S., Holst, Jens Juul, Knop, Filip Krag & Christensen, Mikkel Bring, 2018, In: The Journal of clinical endocrinology and metabolism. 103, 12, p. 4480-4481 2 p.

    Research output: Contribution to journalComment/debateResearch

  67. Published

    Restoration of enteroendocrine and pancreatic function after internal hernia and short bowel syndrome in a young woman with gastric bypass: a 2-year follow-up

    Borghede, M., Vinter-Jensen, L., Rasmussen, H. H., Veedfald, Simon, Rehfeld, Jens Frederik, Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag & Sonne, D. P., 2018, In: Physiological Reports. 6, 9, 6 p., e13686.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    The Effect of Ethanol on Inflammation Markers and FGF-21 in Healthy Individuals

    Lanng, A. R., Gasbjerg, Lærke Smidt, Bergmann, N. C., Møller, H., Gillum, M., Gronbaek, H., Vilsbøll, Tina & Knop, Filip Krag, 2018, In: Diabetes. 67, Supplement 1, 2415-PUB.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    The Role of Glucagon in the Pathophysiology and Treatment of Type 2 Diabetes

    Hædersdal, S., Lund, A., Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Mayo Clinic Proceedings. 93, 2, p. 217-239

    Research output: Contribution to journalReviewResearchpeer-review

  70. Published

    The role of the incretins in the postprandial bone remodelling

    Helsted, M. M., Gasbjerg, Lærke Smidt, Lanng, A. R., Stensen, S., Hartmann, Bolette, Christensen, Mikkel Bring, Holst, Jens Juul, Vilsbøll, Tina, Rosenkilde, M. M. & Knop, Filip Krag, 2018, In: Diabetologia. 61, S1, p. S221-S221 449.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  71. Published

    Tværsektorielt samarbejde ved behandling af patienter med type 2-diabetes

    Munch, L., Røder, M. E., Rasmussen, I. H., Middelfart, H., Kaarsberg, N., Bennich, B., Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Ugeskrift for Laeger. 180, 8, p. 690-693

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Glucose-Dependent Insulinotropic Polypeptide (GIP) Inhibits Bone Resorption Independently of Insulin and Glycemia

    Christensen, Mikkel Bring, Lund, A., Calanna, S., Jørgensen, Niklas Rye, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 1 Jan 2018, In: The Journal of clinical endocrinology and metabolism. 103, 1, p. 288-294

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published
  74. Published

    Glucose-dependent insulinotropic polypeptide (GIP) receptor antagonists as anti-diabetic agents

    Gasbjerg, Lærke Smidt, Gabe, M. B. N., Hartmann, Bolette, Christensen, Mikkel Bring, Knop, Filip Krag, Holst, Jens Juul & Rosenkilde, Mette, Feb 2018, In: Peptides. 100, p. 173-181

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Enteroendocrine K and L cells in healthy and type 2 diabetic individuals

    Jorsal, T., Rhee, N. A., Pedersen, Jens, Wahlgren, C. D., Mortensen, B., Jepsen, Sara Lind, Jelsing, J., Dalbøge, L. S., Vilmann, Peter, Hassan, H., Hendel, J. W., Poulsen, Steen Seier, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 1 Feb 2018, In: Diabetologia. 61, 2, p. 284-294 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    The bile acid-sequestering resin sevelamer eliminates the acute GLP-1 stimulatory effect of endogenously released bile acids in patients with type 2 diabetes

    Brønden, A., Albér, A., Rohde, U., Gasbjerg, Lærke Smidt, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 1 Feb 2018, In: Diabetes, Obesity and Metabolism. 20, 2, p. 362-369

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Effects of glucagon-like peptide-1 receptor agonists on cardiovascular risk factors: A narrative review of head-to-head comparisons

    Dalsgaard, N. B., Vilsbøll, Tina & Knop, Filip Krag, Mar 2018, In: Diabetes, Obesity and Metabolism. 20, 3, p. 508-519

    Research output: Contribution to journalReviewResearchpeer-review

  78. Published

    Guanylin and uroguanylin mRNA expression is increased following Roux-en-Y gastric bypass, but guanylins do not play a significant role in body weight regulation and glycemic control

    Fernandez-Cachon, M. L., Pedersen, S. L., Rigbolt, K. T., Zhang, C., Fabricius, K., Hansen, H. H., Elster, L., Fink, L. N., Schäfer, M., Rhee, N. A., Langholz, E., Wandall, E., Friis, S. U., Vilmann, P., Kristiansen, V. B., Schmidt, C., Schreiter, K., Breitschopf, K., Hübschle, T., Jorsal, T. & 6 others, Vilsbøll, Tina, Schmidt, T., Theis, S., Knop, Filip Krag, Larsen, P. J. & Jelsing, J., Mar 2018, In: Peptides. 101, p. 32-43 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    HYPOGLYCAEMIC EPISODES EVALUATED BY CONTINUOUS GLUCOSE MONITORING IN PATIENTS WITH TYPE 2 DIABETES AND DIALYSIS-DEPENDENT END-STAGE RENAL DISEASE RANDOMISED TO 12-WEEK LIRAGLUTIDE OR PLACEBO TREATMENT

    Bomholt, T., Idorn, T., Knop, Filip Krag, Jorgensen, M. B., Resuli, M., Christensen, Karl Bang, Hansen, P. M., Borg, Rikke, Persson, F., Feldt-Rasmussen, Bo & Hornum, Mads, May 2018, In: Nephrology Dialysis Transplantation. 33, suppl_1, p. 492-492 SP426.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  80. Published

    Effects of Smoking Versus Nonsmoking on Postprandial Glucose Metabolism in Heavy Smokers Compared With Nonsmokers

    Grøndahl, M. F., Bagger, J. I., Lund, A., Faurschou, A., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Jun 2018, In: Diabetes Care. 41, 6, p. 1260-1267

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Ghrelin secretion in humans - a role for the vagus nerve?

    Veedfald, Simon, Plamboeck, A., Hartmann, Bolette, Vilsbøll, Tina, Knop, Filip Krag, Deacon, Carolyn F., Svendsen, Lars Bo & Holst, Jens Juul, Jun 2018, In: Neurogastroenterology and Motility. 30, 6, e13295.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Glucose-lowering effects and mechanisms of the bile acid-sequestering resin sevelamer

    Brønden, A., Mikkelsen, K., Sonne, D. P., Hansen, M., Våben, C., Gabe, M. N., Rosenkilde, Mette, Tremaroli, V., Wu, H., Bäckhed, F., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Jul 2018, In: Diabetes, Obesity and Metabolism. 20, 7, p. 1623-1631

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Is glucagon‐like peptide‐1 fully protected by the dipeptidyl peptidase 4 inhibitor sitagliptin when administered to patients with type 2 diabetes?

    Andersen, E. S., Lund, A., Bagger, J. I., Andreasen, C., Grøndahl, M., Deacon, Carolyn F., Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, Aug 2018, In: Diabetes, Obesity and Metabolism. 20, 8, p. 1937-1943

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Adaptive changes in pancreas post Roux-en-Y gastric bypass induced weight loss

    Lautenbach, A., Wernecke, M., Riedel, N., Veigel, J., Yamamura, J., Keller, S., Jung, R., Busch, P., Mann, O., Knop, Filip Krag, Holst, Jens Juul, Meier, J. J. & Aberle, J., Oct 2018, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 34, 7, p. 1-8 e3025.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Recovery of gut microbiota of healthy adults following antibiotic exposure

    Palleja, A., Mikkelsen, K. H., Forslund, S. K., Kashani, A., Allin, K. H., Nielsen, T., Hansen, T. H., Liang, S., Feng, Q., Zhang, C., Pyl, P. T., Coelho, L. P., Yang, H., Wang, J., Typas, A., Nielsen, M. F., Nielsen, H. B., Bork, P., Wang, J., Vilsbøll, T. & 4 others, Hansen, Torben, Knop, Filip Krag, Arumugam, Mani & Pedersen, Oluf Borbye, Nov 2018, In: Nature Microbiology. 3, 11, p. 1255-1265 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Determinants of Fasting Hyperglucagonemia in Patients with Type 2 Diabetes and Nondiabetic Control Subjects

    Demant, M., Bagger, J. I., Suppli, M. P., Lund, A., Gyldenløve, M., Hansen, K. B., Hare, Kristine Juul, Christensen, Mikkel Bring, Sonne, D. P., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Dec 2018, In: Metabolic Syndrome and Related Disorders. 16, 10, p. 530-536 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. 2019
  88. Published

    N-acyl taurines are endogenous lipid messengers that improve glucose homeostasis

    Grevengoed, Trisha Jean, Trammell, Sam, McKinney, M. K., Petersen, N., Cardone, R. L., Svenningsen, J. S., Ogasawara, D., Nexøe-Larsen, C. C., Knop, Filip Krag, Schwartz, Thue W., Kibbey, R. G., Cravatt, B. F. & Gillum, M. P., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 49, p. 24770-24778

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    A role for exogenous GLP-1 in the management of postprandial hypoglycaemia after Roux-en-Y gastric bypass?

    Øhrstrøm, C. C. & Knop, Filip Krag, 2019, In: European Journal of Endocrinology. 181, 3, p. C5-C8

    Research output: Contribution to journalComment/debateResearch

  90. Published

    Association between topical corticosteroid use and type 2 diabetes in two European population-based adult cohorts

    Andersen, Y. M. F., Egeberg, A., Ban, L., Gran, S., Williams, H. C., Francis, N. A., Knop, Filip Krag, Gislason, Gunnar Hilmar, Skov, Lone & Thyssen, Jacob Pontoppidan, 2019, In: Diabetes Care. 42, 6, p. 1095-1103

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Bariatric surgery in patients with non-alcoholic fatty liver disease from pathophysiology to clinical effects

    Laursen, T. L., Hagemann, C. A., Wei, C., Kazankov, K., Thomsen, K. L., Knop, Filip Krag & Gronbaek, H., 2019, In: World Journal of Hepatology. 11, 2, p. 138-149

    Research output: Contribution to journalReviewResearchpeer-review

  92. Published

    Biomarkører for kardiovaskulær sygdom ved type 2-diabetes

    Krogh, S. K., Andersen, A., Knop, Filip Krag & Vilsbøll, Tina, 2019, In: Ugeskrift for Laeger. 181, 6 p., V10180711.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Bone Status in Obese, Non-diabetic, Antipsychotic-Treated Patients, and Effects of the Glucagon-Like Peptide-1 Receptor Agonist Exenatide on Bone Turnover Markers and Bone Mineral Density

    Eriksson, R., Broberg, B. V., Ishoy, P. L., Bak, N., Andersen, U. B., Jorgensen, N. R., Knop, Filip Krag & Ebdrup, Bjørn, 2019, In: Frontiers in Psychiatry. 9, 7 p., 781.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Clinical characteristics and glucose-lowering drug utilization among patients initiating liraglutide in Denmark: a routine clinical care prescription study

    Knudsen, J. S., Thomsen, R. W., Pottegard, A., Knop, Filip Krag & Sørensen, H. T., 2019, In: Journal of Diabetes. 11, 8, p. 690-694

    Research output: Contribution to journalLetterResearchpeer-review

  95. Published

    Clinical translatability of a diet-induced obese mouse model of non-alcoholic steatohepatitis

    Rigbolt, K., Veidal, S., Suppli, M., Eriksen, P. L., Feigh, M., Knop, Filip Krag, Gronbaek, H., Thomsen, K. L., Jelsing, J. & Vrang, N., 2019, In: Journal of Hepatology. 70, 1, p. E544 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  96. Published

    Continuous glucose monitoring in pregnant women with type 1 diabetes: an observational cohort study of 186 pregnancies

    Kristensen, K., Ögge, L. E., Sengpiel, V., Kjölhede, K., Dotevall, A., Elfvin, A., Knop, Filip Krag, Wiberg, N., Katsarou, A., Shaat, N., Kristensen, L. & Berntorp, K., 2019, In: Diabetologia. 62, 7, p. 1143-1153 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    EFFECT OF LIRAGLUTIDE ON BODY WEIGHT AND PAIN IN THE TREATMENT OF OVERWEIGHT AND KNEE OSTEOARTHRITIS: A RANDOMISED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY

    Gudbergsen, H., Overgaard, A., Henriksen, Marius, Waehrens, E. E., Bliddal, Henning, Christensen, R., Nielsen, S. M., Boesen, Mikael Ploug, Knop, Filip Krag, Astrup, A., Rasmussen, M. U., Bartholdy, C. R., Daugaard, C., Bartels, E. M., Ellegaard, K., Heitmann, Berit & Kristensen, L. E., 2019, In: Annals of the Rheumatic Diseases. 78, p. 71-72 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  98. Published

    Effect of liraglutide on body weight and pain in patients with overweight and knee osteoarthritis: protocol for a randomised, double-blind, placebocontrolled, parallel-group, singlecentre trial

    Gudbergsen, Henrik Rindel, Henriksen, M., Wæhrens, E. E., Overgaard, A., Bliddal, H., Christensen, R., Boesen, Mikael Ploug, Knop, Filip Krag, Astrup, A., Rasmussen, M. U., Bartholdy, C., Daugaard, C., Bartels, E. M., Ellegaard, K., Heitmann, Berit & Kristensen, L. E., 2019, In: B M J Open. 9, 5, 12 p., e024065.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Effects of combined GIP and GLP-1 infusion on energy intake, appetite and energy expenditure in overweight/obese individuals: a randomised, crossover study

    Bergmann, N. C., Lund, A., Gasbjerg, Lærke Smidt, Meessen, E. C. E., Andersen, M. M., Bergmann, S., Hartmann, Bolette, Holst, Jens Juul, Jessen, L., Christensen, Mikkel Bring, Vilsbøll, Tina & Knop, Filip Krag, 2019, In: Diabetologia. 62, 4, p. 665-675 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Endogenous glucose-dependent insulinotropic polypeptide exerts diverging and tissue specific in obese patients with type 2 diabetes

    Stensen, S., Gasbjerg, Lærke Smidt, Krogh, L. L., wbf943, wbf943, Skov-Jeppesen, Kirsa, Jensen, M. H., Hartmann, Bolette, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette, Christensen, M. B. & Knop, Filip Krag, 2019, In: Diabetologia. 62, Supl. 1/SI, p. S270-S271 2 p., 560.

    Research output: Contribution to journalConference abstract in journalResearch

  101. Published

    Extrapancreatic glucagon: Present status

    Lund, A. & Knop, Filip Krag, 2019, In: Diabetes Research and Clinical Practice. 147, p. 19-28

    Research output: Contribution to journalReviewResearchpeer-review

  102. Published

    GIP and GLP-1 Potentiate Sulfonylurea-Induced Insulin Secretion in HNF1A Diabetes

    Christensen, A. S., Haedersdal, S., Storgaard, H., Rose, K., Hansen, N. L., Holst, Jens Juul, Hansen, Torben, Knop, Filip Krag & Vilsbøll, Tina, 2019, In: Diabetes. 68, Suppl. 1, 1 p., 981-P.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  103. Published

    Gastrin secretion in normal subjects and diabetes patients is inhibited by glucagon-like peptide 1: a role in the gastric side effects of GLP-1-derived drugs?

    Rehfeld, Jens Frederik, Knop, Filip Krag & Asmar, M., 2019, In: Scandinavian Journal of Gastroenterology. 54, 12, p. 1448-1451 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 40100368