Filip Krag Knop
Clinical Professor
Department of Clinical Medicine
Borgmester Ib Juuls Vej 1, 2730 Herlev
Member of:
Internal Medicine: Endocrinology
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Influenza vaccination is associated with reduced cardiovascular mortality in adults with diabetes: A nationwide cohort study
Modin, D., Claggett, B., Køber, Lars Valeur, Schou, Morten, Jensen , Jens-Ulrik Stæhr , Solomon, S. D., Vardeny, O., Knop, Filip Krag, Nielsen, Susanne Dam, Fralick, M., Torp-Pedersen, Christian, Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2020, In: Diabetes Care. 43, 9, p. 2226-2233 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibition de la sécrétion du glucagon par les antagonistes du GLP-1 et les inhibiteurs de la DPP-4
Hansen, M., Knop, Filip Krag & Holst, Jens Juul, Apr 2011, In: Medecine des Maladies Metaboliques. 5, 2Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibition of glucagon secretion by GLP-1 agonists and DPP4 inhibitors
Hansen, M., Juul Hare, K., Holst, Jens Juul & Knop, Filip Krag, Jun 2011, In: Journal of Clinical Metabolism & Diabetes. 2, 2, p. 7-13 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Intestinal expression profiles and hepatic expression of LEAP2, ghrelin and their common receptor, GHSR, in humans
Englund, A., Gilliam-Vigh, H., Suppli, M. P., Gasbjerg, Lærke Smidt, Vilsbøll, Tina & Knop, Filip Krag, 2024, In: Peptides. 177, 7 p., 171227.Research output: Contribution to journal › Journal article › Research › peer-review
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Investigating Intestinal Glucagon after Roux-en-Y Gastric Bypass Surgery
Jorsal, T., Wewer Albrechtsen, N. J., Christensen, M. M., Mortensen, B., Wandall, E., Langholz, E., Friis, S., Worm, D., Ørskov, C., Støving, R. K., Andries, A., Juhl, C. B., Sørensen, F., Forman, J. L., Falkenhahn, M., Musholt, P. B., Theis, S., Larsen, P. J., Holst, J. J., Vrang, N. & 3 others, , 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 12, p. 6403–6416 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Involvement of glucagon-like peptide-1 in the glucose-lowering effect of metformin
Bahne, E., Hansen, M., Brønden, A., Sonne, David Peick, Vilsbøll, Tina & Knop, Filip Krag, Oct 2016, In: Diabetes, Obesity and Metabolism Online. 18, 10, p. 955-61 7 p.Research output: Contribution to journal › Review › Research › peer-review
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Involvement of steatosis-induced glucagon resistance in hyperglucagonaemia
Suppli, M. P., Lund, Asger Bach, Bagger, J. I., Vilsbøll, Tina & Knop, Filip Krag, Jan 2016, In: Medical Hypotheses. 86, p. 100-3 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Is double-blinding achievable in a placebo-controlled trial with the glucagon-like-peptide-1 receptor agonist liraglutide?
Foghsgaard, S., Vedtofte, L., Bahne, E., Andreasen, C., Christiansen, L. K., Svare, J. A., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Gluud, Lise Lotte, Knop, Filip Krag & Vilsbøll, Tina, 2017, In: Diabetologia. 60, S1, p. S369-S369Research output: Contribution to journal › Conference abstract in journal › Research
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Is glucagon‐like peptide‐1 fully protected by the dipeptidyl peptidase 4 inhibitor sitagliptin when administered to patients with type 2 diabetes?
Andersen, E. S., Lund, A., Bagger, J. I., Andreasen, C., Grøndahl, M., Deacon, Carolyn F., Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, Aug 2018, In: Diabetes, Obesity and Metabolism. 20, 8, p. 1937-1943Research output: Contribution to journal › Journal article › Research › peer-review
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Julefrokostdilemmaet
Lanng, A. R., Gasbjerg, L. S. & Knop, Filip Krag, 11 Dec 2017, In: Ugeskrift for Laeger. 179, 25, p. 2212-15 4 p., V69590.Research output: Contribution to journal › Journal article › Research › peer-review
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KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide (GIP) in patients with type 2 diabetes
Aaboe, K., Knop, Filip Krag, Vilsbøll, Tina, Vølund, A., Simonsen, U., Deacon, Carolyn F., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 2, p. 603-608Research output: Contribution to journal › Journal article › Research › peer-review
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KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes
Aaboe, K., Knop, Filip Krag, Vilsboll, T., Vølund, A., Simonsen, U., Deacon, Carolyn F., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2008, In: Journal of Clinical Endocrinology and Metabolism. 94, 2, p. 603-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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L-cell Differentiation Is Induced by Bile Acids Through GPBAR1 and Paracrine GLP-1 and Serotonin Signaling
Lund, M. L., Sorrentino, G., Egerod, Kristoffer Lihme, Kroone, C., Mortensen, B., Knop, Filip Krag, Reimann, F., Gribble, F. M., Drucker, D. J., De Koning, E. J. P., Schoonjans, K., Bäckhed, F., Schwartz, Thue W. & Petersen, N., Apr 2020, In: Diabetes. 69, 4, p. 614-623 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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LEAP2 reduces postprandial glucose excursions and ad libitum food intake in healthy men
Hagemann, C. A., Jensen, M. S., Holm, Stephanie Kjærulff, Gasbjerg, Lærke Smidt, Byberg, Sarah, Skov-Jeppesen, Kirsa, Hartmann, Bolette, Holst, Jens Juul, Dela, Flemming, Vilsbøll, Tina, Christensen, Mikkel Bring, Holst, Birgitte & Knop, Filip Krag, 2022, In: Cell Reports Medicine. 3, 4, 100582.Research output: Contribution to journal › Journal article › Research › peer-review
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Lack of effect of the glucagon-like peptide-1 receptor agonist liraglutide on psoriasis in glucose-tolerant patients – a randomized placebo-controlled trial
Faurschou, A., Gyldenløve, M., Rohde, U., Thyssen, Jacob Pontoppidan, Zachariae, Claus, Skov, L., Knop, Filip Krag & Vilsbøll, T., Mar 2015, In: Journal of the European Academy of Dermatology and Venereology. 29, 3, p. 555-559 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lean Women with Polycystic Ovary Syndrome and Insulin Resistance Have Normal Incretin Effect, which Is Unaffected by Metformin Therapy
Vedtofte, L., Foghsgaard, S., Zierau, L., Vilsbøll, Tina & Knop, Filip Krag, 2019, In: Diabetes. 68, Supplement 1, 1 p., 1186-P.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Letter: Bif195 for aspirin-induced gastric mucosal damage – More to do in further research. Authors' reply
Løn, N., Engel, S., Damholt, A., Wellejus, A. & Knop, Filip Krag, 2024, In: Alimentary Pharmacology and Therapeutics. 59, 10, p. 1306-1307 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Lipid and liver abnormalities in haemoglobin A1c-defined prediabetes and type 2 diabetes
Calanna, S., Scicali, R., Di Pino, A., Knop, Filip Krag, Piro, S., Rabuazzo, A. M. & Purrello, F., Jun 2014, In: Nutrition, Metabolism and Cardiovascular Diseases. 24, 6, p. 670-676 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Liraglutide after diet-induced weight loss for pain and weight control in knee osteoarthritis: A randomized controlled trial
Gudbergsen, Henrik Rindel, Overgaard, A., Henriksen, Marius, Wæhrens, E. E., Bliddal, Henning, Christensen, R., Nielsen, S. M., Boesen, Mikael Ploug, Knop, Filip Krag, Astrup, A., Rasmussen, M. U., Bartholdy, C., Daugaard, C. L., Ellegaard, K., Heitmann, Berit, Bartels, E. M., Danneskiold-Samsøe, B. & Kristensen, L. E., 2021, In: American Journal of Clinical Nutrition. 113, 2, p. 314–323 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Liraglutide changes postprandial responses of gut hormones involved in the regulation of gallbladder motility
Nerild, H. H., Brønden, Andreas, Gether, I. M., Hellmann, P. H., Baekdal, M., Gillum, M. P., Svenningsen, J. S., Hartmann, Bolette, Rathor, N., Kudiyanur Muniraju, H. A., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina, Sonne, David Peick & Knop, Filip Krag, 2023, In: Diabetes, Obesity and Metabolism. 25, 6, p. 1632-1637Research output: Contribution to journal › Journal article › Research › peer-review
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Liraglutide decreases postprandial fibroblast growth factor 19 and glucagon-like peptide 2, and increases postprandial cholecystokinin in individuals with obesity
Bronden, A., Nerild, H. H., Nexoe-Larsen, C. C., Hellmann, P. H., Baekdal, M., Gether, I. M., Gillum, M. P., Hartmann, Bolette, Knudsen, L. B., Jacobsen, L. V., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina, Sonne, D. P. & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 94-94 177.Research output: Contribution to journal › Conference abstract in journal › Research
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Liraglutide treatment for the prevention of glucose tolerance deterioration in women with prior gestational diabetes mellitus: A 52-week randomized controlled clinical trial
Foghsgaard, S., Vedtofte, L., Andersen, E. S., Bahne, E., Andreasen, C., Sørensen, A. L., Forman, Julie Lyng, Mathiesen, Elisabeth, Svare, J. A., Clausen, Tine Dalsgaard, Damm, Peter, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2023, In: Diabetes, Obesity and Metabolism. 26, 1, p. 201-214 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Liraglutide treatment is associated with progression of coronary artery fibrous plaque: a prospective 1-year follow-up study in asymptomatic patients with type 2 diabetes
Heinsen, L. J., Pararajasingam, G., Andersen, T. R., Auscher, S., Sheta, H. M., Precht, H., Engdam, K. B., Hangaard, J., Lambrechtsen, J., Knop, Filip Krag & Egstrup, K., 2023, In: BMC Cardiovascular Disorders. 23, 1, 8 p., 214.Research output: Contribution to journal › Journal article › Research › peer-review
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Liraglutide versus colesevelam for treating bile acid diarrhoea – Authors' reply
Kårhus, M. L. & Knop, Filip Krag, 2022, In: The Lancet Gastroenterology and Hepatology. 7, 12, p. 1075-1076 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Liraglutide-Induced Weight Loss May be Affected by Autonomic Regulation in Type 1 Diabetes
Hansen, C. S., Frandsen, C. S., Fleischer, J., Vistisen, D., Holst, Jens Juul, Tarnow, L., Knop, Filip Krag, Madsbad, Sten, Andersen, H. U. & Dejgaard, T. F., 2019, In: Frontiers in Endocrinology. 10, 9 p., 242.Research output: Contribution to journal › Journal article › Research › peer-review
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Lixisenatide for type 2 diabetes mellitus
Christensen, M., Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 2011, In: Expert Opinion on Investigational Drugs. 20, 4, p. 549-57 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lixisenatide, a novel GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus
Christensen, M., Knop, Filip Krag, Holst, Jens Juul & Vilsboll, T., 2009, In: IDrugs. The Investigational Drugs Journal. 12, 8, p. 503-13 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Long-acting GLP-1 analogs for the treatment of type 2 diabetes mellitus
Vilsbøll, Tina & Knop, Filip Krag, 1 Jan 2008, In: BioDrugs. 22, 4, p. 251-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Long-acting amylin analogues for the management of obesity
Mathiesen, D. S., Bagger, J. I. & Knop, Filip Krag, 2022, In: Current Opinion in Endocrinology, Diabetes and Obesity. 29, 2, p. 183-190 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Loss of Incretin Effect Is a Specific, Important, and Early Characteristic of Type 2 Diabetes
Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina, Krarup, T. & Madsbad, Sten, May 2011, In: Diabetes Care. 34, Supplement 2, p. S251-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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MECHANISMS IN ENDOCRINOLOGY: The physiology of neuronostatin
Andersen, M. R., Suppli, M. P., Bagger, J. I., Christensen, Mikkel Bring, Yosten, G. L. C., Knop, Filip Krag & Lund, A., 2021, In: European Journal of Endocrinology. 185, 4, p. R93-R101Research output: Contribution to journal › Review › Research › peer-review
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MRI-Based Quantification of Pan-Alimentary Function and Motility in Subjects with Diabetes and Gastrointestinal Symptoms
Bertoli, D., Mark, E. B., Liao, D., Okdahl, T., Nauser, S., Daugberg, L. H., Brock, C., Brock, Birgitte, Knop, Filip Krag, Krogh, K., Brøndum Frøkjær, J. & Drewes, A. M., 2023, In: Journal of Clinical Medicine. 12, 18, 16 p., 5968.Research output: Contribution to journal › Journal article › Research › peer-review
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Management of Patients with Type 2 Diabetes Shared between a Specialized Outpatient Clinic and General Practice Was Noninferior to Mono Management in a Specialized Outpatient Clinic—A Prospective, Randomized, Noninferiority Trial
Munch, L., Bennich, B. B., Overgaard, D., Konradsen, Hanne, Middelfart, H. V., Kaarsberg, N., Knop, Filip Krag, Vilsbøll, Tina & Røder, M., 2018, In: Diabetes. 67, Supplement 1, 6-OR.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Management of dyslipidaemia in individuals with severe mental illness: a population-based study in the Greater Copenhagen Area
Høgnason Mohr, G., Barcella, C. A., Grand, Mia Klinten, Kriegbaum, Margit, Siersma, Volkert Dirk, Hahn, M. K., Agarwal, S. M., Bakkedal, Catrine, Baandrup, Lone, Knop, Filip Krag, Andersen, C. L. & Ebdrup, Bjørn, 2023, In: Therapeutic Advances in Psychopharmacology. 13, 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Management of people with Type 2 diabetes shared between a specialized outpatient clinic and primary health care is noninferior to management in a specialized outpatient clinic: a randomized, noninferiority trial
Munch, L., Bennich, B. B., Overgaard, D., Konradsen, H., Middelfart, H., Kaarsberg, N., Knop, Filip Krag, Vilsbøll, Tina & Røder, M. E., 2019, In: Diabetic Medicine. 36, 7, p. 854-861Research output: Contribution to journal › Journal article › Research › peer-review
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Mapping prohormone processing by proteases in human enteroendocrine cells using genetically engineered organoid models
Beumer, J., Bauzá-Martinez, J., Veth, T. S., Geurts, V., Boot, C., Gilliam-Vigh, H., Poulsen, Steen Seier, Knop, Filip Krag, Wu, W. & Clevers, H., 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 46, 11 p., e2212057119.Research output: Contribution to journal › Journal article › Research › peer-review
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Mathematical Modelling of Glucose-Dependent Insulinotropic Polypeptide and Glucagon-like Peptide-1 following Ingestion of Glucose
Røge, R. M., Bagger, J. I., Alskär, O., Kristensen, N. R., Klim, S., Holst, Jens Juul, Ingwersen, S. H., Karlsson, M. O., Knop, Filip Krag, Vilsbøll, Tina & Kjellsson, M. C., Oct 2017, In: Basic & Clinical Pharmacology & Toxicology. 121, 4, p. 290-297 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mechanism-Based Modeling of Gastric Emptying Rate and Gallbladder Emptying in Response to Caloric Intake
Guiastrennec, B., Sonne, D. P., Hansen, M., Bagger, J. I., Lund, A., Rehfeld, Jens Frederik, Alskär, O., Karlsson, M. O., Vilsbøll, Tina, Knop, Filip Krag & Bergstrand, M., Dec 2016, In: C P T: Pharmacometrics & Systems Pharmacology. 5, 12, p. 692-700 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mechanisms of the incretin effect in subjects with normal glucose tolerance and patients with type 2 diabetes
Mari, A., Bagger, J. I., Ferrannini, E., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 2013, In: PLOS ONE. 8, 9, p. e73154Research output: Contribution to journal › Journal article › Research › peer-review
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Metabolic effects of one-week binge drinking and fast food intake during Roskilde Festival in young healthy male adults
Demant, Mia Grønlund, Suppli, M. P., Foghsgaard, S., Gether, L., Grøndahl, M. F. G., Dalsgaard, N. B., Bergmann, S. S., Lanng, A. R., Gasbjerg, Lærke Smidt, Thomasen, M., Bagger, J. I., Strandberg, C., Kønig, M. J., Grønbæk, H., Becker, U., Holst, Jens Juul, Knop, J., Gillum, M. P., Vilsbøll, Tina & Knop, Filip Krag, Apr 2021, In: European Journal of Endocrinology. 185, 1, p. 23-32Research output: Contribution to journal › Journal article › Research › peer-review
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Metabolic profile in patients with newly diagnosed bipolar disorder and their unaffected first-degree relatives
Coello, K., Vinberg, Maj, Knop, Filip Krag, Pedersen, Bente Klarlund, McIntyre, R. S., Kessing, Lars Vedel & Munkholm, K., 2019, In: International Journal of Bipolar Disorders. 7, 13 p., 8.Research output: Contribution to journal › Journal article › Research › peer-review
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Metformin er en mulig glukagonlignende peptid-1-stimulator
Bahne, E., Brønden, A., Vilsbøll, Tina & Knop, Filip Krag, 2018, In: Ugeskrift for Laeger. 180, 12, 4 p., V07170516.Research output: Contribution to journal › Journal article › Research › peer-review
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Metformin potentiates bile acid-induced GLP-1 secretion in patients with type 2 diabetes
Bronden, A., Alber, A., Rohde, U., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Diabetologia. 60, p. 113-113 242.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Metformin treatment is associated with reduced risk of hypoglycaemia, major adverse cardiovascular events, and all-cause mortality in patients with post-pancreatitis diabetes mellitus: a nationwide cohort study
Davidsen, L., Jensen, M. H., Cook, M. E., Vestergaard, P., Knop, Filip Krag, Drewes, A. M. & Olesen, S. S., 2024, In: European Journal of Endocrinology. 190, 1, p. 44-53 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Metformin-induced glucagon-like peptide-1 secretion contributes to the actions of metformin in type 2 diabetes
Bahne, E., Sun, E. W. L., Young, R. L., Hansen, M., Sonne, D. P., Hansen, J. S., Rohde, U., Liou, A. P., Jackson, M. L., de Fontgalland, D., Rabbitt, P., Hollington, P., Sposato, L., Due, S., Wattchow, D. A., Rehfeld, Jens Frederik, Holst, Jens Juul, Keating, D. J., Vilsbøll, Tina & Knop, Filip Krag, 2018, In: JCI Insight. 3, 23, p. 1-16 e93936.Research output: Contribution to journal › Journal article › Research › peer-review
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Model-Based Prediction of Plasma Concentration and Enterohepatic Circulation of Total Bile Acids in Humans
Guiastrennec, B., Sonne, David Peick, Bergstrand, M., Vilsbøll, Tina, Knop, Filip Krag & Karlsson, M. O., 2018, In: C P T: Pharmacometrics & Systems Pharmacology. 7, 9, p. 603-612Research output: Contribution to journal › Journal article › Research › peer-review
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Mono- and co-activation of the GIP and GLP-1 receptors inhibits bone resorption
Bergmann, N. C., Lund, A., Heimburger, S. M., Gasbjerg, Lærke Smidt, Jørgensen, Niklas Rye, Jessen, L., Hartmann, Bolette, Holst, Jens Juul, Christensen, Mikkel Bring, Vilsbøll, Tina & Knop, Filip Krag, 2018, In: Diabetologia. 61, S.1, p. S348-S348 717.Research output: Contribution to journal › Conference abstract in journal › Research
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Myocardial Impairment and Acute Respiratory Distress Syndrome in Hospitalized Patients With COVID-19: The ECHOVID-19 Study
Skaarup, K. G., Lassen, M. C. H., Lind, J. N., Alhakak, A. S., Sengeløv, M., Nielsen, A. B., Espersen, C., Hauser, R., Schöps, L. B., Holt, E., Johansen, N. D., Modin, D., Sharma, S., Graff, C., Bundgaard, H., Hassager, C., Jabbari, R., Lebech, A. M., Kirk, O., Bødtger, U. & 22 others, , 2020, In: JACC: Cardiovascular Imaging. 13, 11, p. 2474-2476 3 p.Research output: Contribution to journal › Letter › Research › peer-review
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N- and C-terminally truncated forms of glucose-dependent insulinotropic polypeptide are high-affinity competitive antagonists of the human GIP receptor
Hansen, L. S., wbf943, wbf943, Christensen, M., Knop, Filip Krag, Hartmann, Bolette, Holst, Jens Juul & Rosenkilde, Mette, Mar 2016, In: British Journal of Pharmacology. 173, 5, p. 826-838 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Near normalisation of blood glucose improves the potentiating effect of GLP-1 on glucose-induced insulin secretion in patients with type 2 diabetes
Højberg, P. V., Zander, M., Vilsbøll, T., Knop, Filip Krag, Krarup, T., Vølund, A., Holst, Jens Juul & Madsbad, Sten, 1 Apr 2008, In: Diabetologia. 51, 4, p. 632-640 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Near-normalization of glycaemic control with glucagon-like peptide-1 receptor agonist treatment combined with exercise in patients with type 2 diabetes
Mensberg, P., Nyby, S., Jørgensen, P. G., Storgaard, H., Jensen, M. T., Sivertsen, J., Holst, Jens Juul, Kiens, Bente, Richter, Erik A., Knop, Filip Krag & Vilsbøll, Tina, 2017, In: Diabetes, Obesity and Metabolism. 19, 2, p. 172-180 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Neurotensin secretion after Roux-en-Y gastric bypass, sleeve gastrectomy, and truncal vagotomy with pyloroplasty
Svane, M. S., Øhrstrøm, C. C., Plamboeck, A., Jørgensen, Nils Bruun, Bojsen-Møller, K. N., Dirksen, C., Martinussen, C., Vilsbøll, Tina, Hartmann, Bolette, Deacon, Carolyn F., Kristiansen, V. B., Knop, Filip Krag, Svendsen, Lars Bo, Madsbad, Sten, Holst, Jens Juul & Veedfald, Simon, 2022, In: Neurogastroenterology and Motility. 34, 1, e14210.Research output: Contribution to journal › Journal article › Research › peer-review
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New Avenues in the Regulation of Gallbladder Motility: Implications for the Use of Glucagon-Like Peptide-Derived Drugs
Gether, I. M., Nexøe-Larsen, C. & Knop, Filip Krag, 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 7, p. 2463-2472Research output: Contribution to journal › Review › Research › peer-review
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No Acute Effects of Exogenous Glucose-Dependent Insulinotropic Polypeptide on Energy Intake, Appetite, or Energy Expenditure When Added to Treatment With a Long-Acting Glucagon-Like Peptide 1 Receptor Agonist in Men With Type 2 Diabetes
Bergmann, N. C., Gasbjerg, Lærke Smidt, Heimbürger, S. M., Krogh, L. S. L., Dela, Flemming, Hartmann, Bolette, Holst, Jens Juul, Jessen, L., Christensen, Mikkel Bring, Vilsbøll, Tina, Lund, A. & Knop, Filip Krag, 2020, In: Diabetes Care. 43, 3, p. 588-596 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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No changes in levels of bone formation and resorption markers following a broad-spectrum antibiotic course
Mikkelsen, K. H., Vilsbøll, Tina, Holst, Jens Juul, Hartmann, Bolette, Knop, Filip Krag & Frost, M., 2018, In: BMC Endocrine Disorders. 18, 6 p., 60.Research output: Contribution to journal › Journal article › Research › peer-review
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No cognitive-enhancing effect of GLP-1 receptor agonism in antipsychotic-treated, obese patients with schizophrenia
Ishøy, P. L., Fagerlund, Birgitte, Broberg, B. V., Bak, N., Knop, Filip Krag, Glenthøj, Birte Yding & Ebdrup, Bjørn, Jul 2017, In: Acta Psychiatrica Scandinavica. 136, 1, p. 52-62Research output: Contribution to journal › Journal article › Research › peer-review
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No detectable effect of a type 2 diabetes-associated TCF7L2 genotype on the incretin effect
Mathiesen, D. S., Bagger, J., Hansen, K. B., Junker, A. E., Plamboeck, A., Harring, S., Idorn, T., Hornum, M., Holst, Jens Juul, Jonsson, Anna Elisabet, Hansen, Torben, Vilsbøll, Tina, Lund, Asger Bach & Knop, Filip Krag, 2020, In: Endocrine Connections. 9, 12, p. 1221-1232 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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No effect of the turmeric root phenol curcumin on prednisolone-induced gluco-metabolic perturbations in men with overweight or obesity
Hellmann, P. H., Bagger, J. I., Carlander, K. R., Hansen, K. B., Forman, Julie Lyng, Størling, Joachim, Chabanova, E., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: Endocrine Connections. 12, 4, e220334.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No hypoglycemia after subcutaneous administration of glucagon-like peptide-1 in lean type 2 diabetic patients and in patients with diabetes secondary to chronic pancreatitis.
Knop, Filip Krag, Vilsbøll, Tina, Larsen, S., Madsbad, Sten, Holst, J. J. & Krarup, T., 2003, In: Diabetes Care. 26, 9, p. 2581-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Non-alcoholic fatty liver disease alters expression of genes governing hepatic nitrogen conversion
Eriksen, P. L., Vilstrup, H., Rigbolt, K., Suppli, M. P., Sørensen, M., Heebøll, S., Veidal, S. S., Knop, Filip Krag & Thomsen, K. L., 2019, In: Liver International. 39, 11, p. 2094-2101Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nonalcoholic Fatty Liver Disease Is Prevalent in Women With Prior Gestational Diabetes Mellitus and Independently Associated With Insulin Resistance and Waist Circumference
Foghsgaard, S., Andreasen, C., Vedtofte, L., Andersen, E. S., Bahne, E., Strandberg, C., Buhl, T., Holst, Jens Juul, Svare, J. A., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Gluud, Lise Lotte, Knop, Filip Krag & Vilsbøll, Tina, Jan 2017, In: Diabetes Care. 40, 1, p. 109-116 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nonalcoholic Fatty Liver Disease in Patients with Type 2 Diabetes and Chronic Kidney Disease
Adrian, T., Hornum, Mads, Knop, Filip Krag, Almdal, Thomas Peter, Rossing, Peter, Lida, L., Heinrich, N. S., Boer, V. O., Marsman, A., Petersen, E. T., Siebner, Hartwig Roman & Feldt-Rasmussen, Bo, 2023, In: Nephron. 147, 6, p. 317–328Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Normal insulin sensitivity, glucose tolerance, gut incretin and pancreatic hormone responses in adults with atopic dermatitis
Gether, L., Thyssen, Jacob Pontoppidan, Gyldenlove, M., Hartmann, Bolette, Holst, Jens Juul, Foghsgaard, S., Vilsbøll, Tina & Knop, Filip Krag, 2020, In: Diabetes, Obesity and Metabolism. 22, 11, p. 2161-2169 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
O12.4. EFFECTS OF THE GLUCAGON-LIKE PEPTIDE-1 RECEPTOR AGONIST EXENATIDE ON BONE STATUS IN OBESE, NON-DIABETIC, ANTIPSYCHOTIC-TREATED SCHIZOPHRENIA SPECTRUM PATIENTS
Eriksson, R., Broberg, B. V., Ishoy, P. L., Bak, N., Andersen, U. B., Jørgensen, Niklas Rye, Knop, Filip Krag & Ebdrup, Bjørn, 2019, In: Schizophrenia Bulletin. 45, Suppl. 2, p. S198-S199 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
On the role of gallbladder emptying and incretin hormones for nutrient-mediated TSH suppression in patients with type 2 diabetes
Sonne, David Peick, Lund, Asger Bach, Faber, J., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Dec 2014, In: Endocrine Connections. 3, 4, p. 193-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Once-weekly GLP-1 agonists: How do they differ from exenatide and liraglutide?
Christensen, M. & Knop, Filip Krag, 1 Apr 2010, In: Current Diabetes Reports. 10, 2, p. 124-32 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Once-weekly subcutaneous semaglutide treatment for persons with type 2 diabetes: Real-world data from a diabetes out-patient clinic
Hansen, K. B., Svendstrup, M., Lund, A., Knop, Filip Krag, Vilsbøll, Tina & drb459, drb459, 2021, In: Diabetic Medicine. 38, 10, p. e14655Research output: Contribution to journal › Review › Research › peer-review
- Published
One Year's Treatment with the Glucagon-Like Peptide 1 Receptor Agonist Liraglutide Decreases Hepatic Fat Content in Women with Nonalcoholic Fatty Liver Disease and Prior Gestational Diabetes Mellitus in a Randomized, Placebo-Controlled Trial
Vedtofte, L., Bahne, E., Foghsgaard, S., Bagger, J. I., Andreasen, C., Strandberg, C., Gortz, P. M., Holst, Jens Juul, Gronbaek, H., Svare, J. A., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Gluud, Lise Lotte, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Journal of Clinical Medicine. 9, 10, 14 p., 3213.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oral glucose has little or no effect on appetite and satiety sensations despite a significant gastrointestinal response
Lauritsen, J. V., Bergmann, N., Junker, A. E., Gyldenløve, Mette, Skov, Lone, Gluud, Lise Lotte, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: European Journal of Endocrinology. 189, 6, p. 619-626 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oral semaglutide 50 mg taken once per day in adults with overweight or obesity (OASIS 1): a randomised, double-blind, placebo-controlled, phase 3 trial
OASIS 1 Investigators, O. 1. I., 2023, In: The Lancet. 402, 10403, p. 705-719 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxyntomodulin Identified as a Marker of Type 2 Diabetes and Gastric Bypass Surgery by Mass-spectrometry Based Profiling of Human Plasma
Albrechtsen, Nicolai Jacob Wewer, Hornburg, D., Albrechtsen, Reidar, Svendsen, B., Toräng, S., Jepsen, Sara Lind, Kuhre, Rune Ehrenreich, Hansen, M., Janus, C., Floyd, A., Lund, Asger Bach, Vilsbøll, Tina, Knop, Filip Krag, drb459, drb459, Deacon, Carolyn F., Meissner, F., Mann, Matthias, Holst, Jens Juul & Hartmann, Bolette, May 2016, In: EBioMedicine. 7, p. 112-120 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Palaeolithic diet decreases fasting plasma leptin concentrations more than a diabetes diet in patients with type 2 diabetes: A randomised cross-over trial
Fontes-Villalba, M., Lindeberg, S., Granfeldt, Y., Knop, Filip Krag, Memon, A. A., Carrera-Bastos, P., Picazo, Ó., Chanrai, M., Sunquist, J., Sundquist, K. & Jönsson, T., 2016, In: Cardiovascular Diabetology. 15, 1, 10 p., 80.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pan-alimentary assessment of motility, luminal content, and structures: an MRI-based framework
Bertoli, D., Mark, E. B., Liao, D., Brock, C., Brock, Birgitte, Knop, Filip Krag, Krogh, K., Frøkjær, J. B. & Drewes, A. M., 2023, In: Scandinavian Journal of Gastroenterology. 58, 12, p. 1378–1390 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pancreatic Amylase and Lipase Plasma Concentrations Are Unaffected by Increments in Endogenous GLP-1 Levels Following Liquid Meal Tests
Sonne, David Peick, Vilsbøll, T. & Knop, Filip Krag, 2015, In: Diabetes Care. 38, 5, p. e71-2 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pancreatic polypeptide: A potential biomarker of glucose-dependent insulinotropic polypeptide receptor activation in vivo
Veedfald, Simon, Bergmann, N. C., Vilsbøll, Tina, Christensen, Mikkel Bring, Holst, Jens Juul & Knop, Filip Krag, May 2021, In: Diabetic Medicine Online. 38, 8, e14592.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Pancreatic polypeptide responses to isoglycemic oral and intravenous glucose in humans with and without intact vagal innervation
Veedfald, Simon, Plamboeck, A., Hartmann, Bolette, Svendsen, Lars Bo, Vilsbøll, T., Knop, Filip Krag & Holst, Jens Juul, Sep 2015, In: Peptides. 71, p. 229-31 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Parenteral nutrition impairs plasma bile acid and gut hormone responses to mixed meal testing in lean healthy men
Meessen, E. C. E., Bakker, G. J., Nieuwdorp, M., Dallinga-Thie, G. M., Kemper, E. M., Olde Damink, S. W., Romijn, J. A., Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag, Groen, A. K., Schaap, F. G. & Soeters, M. R., 2021, In: Clinical Nutrition. 40, 3, p. 1013-1021Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patient Assessment of Family Function, Glycemic Control and Quality of Life in Adult Patients With Type 2 Diabetes and Incipient Complications
Bennich, B. B., Munch, L., Egerod, Ingrid Eugenie, Konradsen, H., Ladelund, S., Knop, Filip Krag, Vilsbøll, Tina, Røder, M. & Overgaard, D., 2019, In: Canadian Journal of Diabetes. 43, 3, p. 193-200Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patients with psoriasis are insulin resistant
Gyldenløve, M., Storgaard, H., Holst, Jens Juul, Vilsbøll, T., Knop, Filip Krag & Skov, Lone, Apr 2015, In: Journal of the American Academy of Dermatology. 72, 4, p. 599-605 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma YKL-40 during pregnancy and gestational diabetes mellitus
Rinnov, A. R., Rathcke, C. N., Bonde, L., Vilsbøll, Tina & Knop, Filip Krag, 2015, In: Journal of Reproductive Immunology. 112, p. 68-72Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease
Niu, Lili, Geyer, P. E., Albrechtsen, Nicolai Jacob Wewer, Gluud, Lise Lotte, Santos, A., Doll, S., Treit, P. V., Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina, Junker, A., Sachs, S., Stemmer, K., Müller, T. D., Tschöp, M. H., Hofmann, S. M. & Mann, Matthias, 2019, In: Molecular Systems Biology. 15, 16 p., e8793.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma proteome profiling discovers potential biomarkers of non-alcoholic fatty liver disease
Niu, Lili, Gupta, R., Geyer, P. E., Albrechtsen, Nicolai Jacob Wewer, Gluud, Lise Lotte, Santos, A., Doll, S., Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina, Junker, A., Sachs, S., Stemmer, K., Mueller, T. D., Tschoep, M. H., Hofmann, S. M. & Mann, Matthias, Aug 2019, In: Molecular & Cellular Proteomics. 18, 8, p. S71 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Positioning Glucagon-like-peptide-1-based Treatment within an Optimal Manegement Regimen for Type 2 Diabetes
Hansen, K. B., Vilsboll, T. & Knop, Filip Krag, 2008, In: European Journal of Endocrinology. Supplement. 4, p. 44-47 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial Plasma Concentrations of Individual Bile Acids and FGF-19 in Patients With Type 2 Diabetes
Sonne, David Peick, van Nierop, F. S., Kulik, W., Soeters, M. R., Vilsbøll, Tina & Knop, Filip Krag, Aug 2016, In: Endocrinology. 101, 8, p. 3002-3009 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial Plasma Concentrations of ProANP in Patients with Type 2 Diabetes and Healthy Controls
Sonne, D. P., Terzic, D., Knop, Filip Krag & Goetze, Jens P. , May 2017, In: Clinical Chemistry. 63, 5, p. 1040-1041 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Postprandial effects of individual and combined GIP and GLP-1 receptor antagonism in healthy subjects
Gasbjerg, Lærke Smidt, Helsted, M. M., wbf943, wbf943, Lanng, A. R., Stensen, S., Jakobsen, M. H., Hartmann, Bolette, Christensen, Mikkel Bring, Holst, Jens Juul, Vilsbøll, Tina, Rosenkilde, M. M. & Knop, Filip Krag, 2018, In: Diabetologia. 61, S1, p. S246-S246 503.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Postprandial gallbladder emptying in patients with type 2 diabetes: potential implications for bile-induced secretion of glucagon-like peptide 1
Sonne, David Peick, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Oct 2014, In: European Journal of Endocrinology. 171, 4, p. 407-419 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial gut hormone responses and glucose metabolism in cholecystectomized patients
Sonne, D. P., Hare, K. J., Martens, P., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 15 Feb 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 304, 4, p. G413-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial incretin and islet hormone responses and dipeptidyl-peptidase 4 enzymatic activity in patients with maturity onset diabetes of the young
Østoft, S. H., Bagger, J. I., Hansen, Torben, Hartmann, Bolette, Pedersen, Oluf Borbye, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 1 Aug 2015, In: European Journal of Endocrinology. 173, 2, p. 205-215 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial prolactin suppression appears absent in antipsychotic-treated male patients
Coello, K., Broberg, B. V., Bak, N., Madsen, A., Mortensen, H. B., Søgaard, B., Szecsi, P. B., Knop, Filip Krag, Lublin, H. & Ebdrup, B. H., Oct 2015, In: Psychoneuroendocrinology. 60, p. 1-6 6 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Postprandial responses of incretin and pancreatic hormones in non-diabetic patients with end-stage renal disease
Idorn, T., Knop, Filip Krag, Jørgensen, M., Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Jan 2014, In: Nephrology, Dialysis, Transplantation. 29, 1, p. 119-27 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preclinical discovery and development of colesevelam for the treatment of type 2 diabetes
Nerild, H. H., Christensen, Mikkel Bring, Knop, Filip Krag & Brønden, A., 2018, In: Expert Opinion on Drug Discovery. 13, 12, p. 1161-1167 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prediabetes Defined by First Measured HbA1c Predicts Higher Cardiovascular Risk Compared With HbA1c in the Diabetes Range: A Cohort Study of Nationwide Registries
Yahyavi, S. K., Snorgaard, O., Knop, Filip Krag, Schou, Morten, Lee, C., Selmer, C., Gislason, Gunnar Hilmar, Torp-Pedersen, Christian, Blomberg Jensen, M. & Nissen Bonde, A., 2021, In: Diabetes Care. 44, 12, p. 2767-2774 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Predictors of Improvement in Quality of Life When Treating Hypothyroidism
Medici, B. B., Lerche la Cour, J., Knop, Filip Krag, Krakauer, M., Michaelsson, L. F., Faber, Jens, Watt, Torquil & Nygaard, Birte, 2021, In: Journal of Thyroid Research. 2021, 7 p., 5577217.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pregnancy loss is associated with type 2 diabetes: a nationwide case-control study
Egerup, P., Mikkelsen, A. P., Kolte, A. M., Westergaard, D., Rasmussen, S., Knop, Filip Krag, Lidegaard, Øjvind & Nielsen, Henriette Svarre, 2020, In: Diabetologia. 63, 8, p. 1521-1529Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Premature explantation of an EndoBarrier gastrointestinal liner because of sleeve invagination
Rohde, U., Federspiel, C. A., Vilmann, Peter, Friis, S. U., Langholz, E., Vilsbøll, Tina & Knop, Filip Krag, 2015, In: Endoscopy. 47 , Suppl 1 , p. E275-6 2 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Preserved inhibitory potency of GLP-1 on glucagon secretion in type 2 diabetes mellitus
Hare, K. J., Knop, Filip Krag, Asmar, M., Madsbad, Sten, Deacon, Carolyn F., Holst, Jens Juul & Vilsbøll, Tina, 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 12, p. 4679-87 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preserved postprandial GLP-1 and GIP responses in patients with maturity onset diabetes of the young
Bagger, J. I., Ostoft, S. H., Hansen, T., Pedersen, O., Holst, Jens Juul, Knop, Filip Krag & Vilsboll, T., 2013, In: Diabetologia. 56, p. S152-S152Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prevalence and predictive features of metabolic dysfunction-associated steatotic liver disease in type 1 diabetes
Fuhri Snethlage, C. M., Meijnikman, A. S., Mak, A. L., Rampanelli, E., Voermans, B., Callender, C. A. K., De Groen, P., Roep, B. O., Van Raalte, D. H., Knop, Filip Krag, Holleboom, A. G., Nieuwdorp, M. & Hanssen, N. M. J., 2024, In: European Journal of Endocrinology. 190, 5, p. 391-400 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prevalence of non-alcoholic fatty liver disease in patients with chronic kidney disease: a cross-sectional study
Adrian, T., Sørensen, I. M. H., Knop, Filip Krag, Bro, S., Ballegaard, E. L. F., Nordestgaard, Børge, Fuchs, A., Kofoed, Klaus Fuglsang, Kühl, J. T., Sigvardsen, P. E., Hornum, Mads & Feldt-Rasmussen, Bo, 2022, In: Nephrology Dialysis Transplantation. 37, 10, p. 1927-1934 gfab266.Research output: Contribution to journal › Journal article › Research › peer-review
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L-cell Differentiation Is Induced by Bile Acids Through GPBAR1 and Paracrine GLP-1 and Serotonin Signaling
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Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease
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Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production
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