Sten Madsbad
Clinical Professor
Department of Clinical Medicine
Kettegård Allé 30, 2650 Hvidovre
Member of:
Internal Medicine: Endocrinology
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Hyperproinsulinaemia in normoglycaemic lipodystrophic HIV-infected patients
Haugaard, S. B., Andersen, Ove, Hales, C., Halsall, I., Rosenfalck, A., Iversen, J. & Madsbad, Sten, 2006, In: European Journal of Clinical Investigation. 36, p. 436-445 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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IRS-1 serine phosphorylation and insulin resistance in skeletal muscle from pancreas tranplant recipient
Bouzakri, K., Karlsson, H., Vestergaard, H., Madsbad, Sten, Christiansen, E. & Zierath, J., 2006, In: Diabetes. 55, p. 785-91 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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IRS-1 serine phosphorylation and insulin resistance in skeletal muscle from pancreas transplant recipients
Bouzakri, K., Karlsson, H. K. R., drb459, drb459, Madsbad, Sten, Christiansen, E. & Zierath, Juleen R, Mar 2006, In: Diabetes. 55, 3, p. 785-91 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Immediate enhancement of first-phase insulin secretion and unchanged glucose effectiveness in patients with type 2 diabetes after Roux-en-Y gastric bypass
Martinussen, C., Bojsen-Moller, K. N., Dirksen, C., Jacobsen, S. H., Jørgensen, N. B., Kristiansen, V. B., Holst, Jens Juul & Madsbad, Sten, 15 Mar 2015, In: American Journal of Physiology: Endocrinology and Metabolism. 308, 6, p. E535-44 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of baseline characteristics and beta-cell function on the efficacy and safety of subcutaneous once-weekly semaglutide: A patient-level, pooled analysis of the SUSTAIN 1-5 trials
Aroda, V. R., Capehorn, M. S., Chaykin, L., Frias, J. P., Lausvig, N. L., Macura, S., Lüdemann, J., Madsbad, Sten, Rosenstock, J., Tabak, O., Tadayon, S. & Bain, S. C., 2020, In: Diabetes, Obesity and Metabolism. 22, 3, p. 303-314Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation
Sparsø, T., Andersen, G., Albrechtsen, Anders, Jørgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Wasson, J., Permutt, M. A., Glaser, B., Madsbad, Sten, Pedersen, Oluf Borbye & Hansen, Torben, 2008, In: Diabetologia. 51, 9, p. 1646-52 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of postprandial glucose control on diabetes-related complications: How is the evidence evolving?
Madsbad, Sten, Mar 2016, In: Journal of Diabetes and its Complications. 30, 2, p. 374-85 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of prolonged fasting on insulin secretion, insulin action, and hepatic versus whole body insulin secretion disposition indices in healthy young males
Jørgensen, S. W., Hjort, L., Gillberg, Linn, Justesen, L., Madsbad, Sten, Brøns, C. & Vaag, Allan, 2021, In: American Journal of Physiology - Endocrinology and Metabolism. 320, 2, p. E281-E290 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impaired incretin effect and fasting hyperglucagonaemia characterizing type 2 diabetic subjects are early signs of dysmetabolism in obesity
Knop, Filip Krag, Aaboe, K., Vilsbøll, Tina, Vølund, A., Holst, Jens Juul, Krarup, T. & Madsbad, Sten, 2012, In: Diabetes, Obesity and Metabolism. 14, 6, p. 500-510 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impaired insulin-stimulated nonoxidative glucose metabolism in pancreas-kidney transplant recipients: dose-response effects of insulin on glucose turnover
Christiansen, E., drb459, drb459, Tibell, A., Hother-Nielsen, O., Holst, Jens Juul, Pedersen, O. & Madsbad, Sten, 1996, In: Diabetes. 45, 9, p. 1267-75 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impaired proinsulin secretion before and during oral glucose stimulation in HIV-infected patients who display fat redistribution.
Haugaard, S. B., Andersen, Ove, Halsall, I., Iversen, J., Hales, C. N. & Madsbad, Sten, 2007, In: Metabolism. 56, 7, p. 939-46 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Importance of endogenous GLP-1 and GIP for postprandial glucose tolerance after Roux-en-Y gastric bypass and sleeve gastrectomy surgery
Hindso, M., Hedback, N., Moller, A., Svane, M. S., Martinussen, C., Jorgensen, N. B., Dirksen, C., Gasbjerg, Lærke Smidt, Kristiansen, V. B., Hartmann, Bolette, Rosenkilde, Mette, Holst, Jens Juul, Madsbad, Sten & Bojsen-Moller, K. N., 2021, In: Diabetologia. 64, SUPPL 1, p. 200-201 387.Research output: Contribution to journal › Conference abstract in journal › Research
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Improved glycaemic control decreases inner mitochondrial membrane leak in type 2 diabetes
Rabøl, R., Højberg, P. M. V., Almdal, Thomas Peter, Boushel, R., Haugaard, S. B., Madsbad, Sten, Dela, Flemming, Rabøl, R., Højberg, P. M. V., Almdal, T., Boushel, R., Haugaard, S. B., Madsbad, Sten & Dela, F., 2009, In: Diabetic Medicine. 11, 4, p. 355-60 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Improved glycemic control with no weight increase in patients with type 2 diabetes after once-daily treatment with the long-acting glucagon-like peptide 1 analog liraglutide (NN2211): a 12-week, double-blind, randomized, controlled trial.
Madsbad, Sten, Schmitz, O., Ranstam, J., Jakobsen, G., Matthews, D. R. & NN, N., 2004, In: Diabetes Care. 27, 6, p. 1335-1342 8 p.Research output: Contribution to journal › Journal article › Research
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Improved postprandial glycaemic control with insulin Aspart in type 2 diabetic patients treated with insulin.
Rosenfalck, A. M., Thorsby, P., Kjems, L., Birkeland, K., Dejgaard, A., Hanssen, K. F. & Madsbad, Sten, 2000, In: Acta Diabetologica. 37, 1, p. 41-46 6 p.Research output: Contribution to journal › Journal article › Research
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Improvements in glucose metabolism early after gastric bypass surgery are not explained by increases in total bile acids and fibroblast growth factor 19 concentrations
Jørgensen, N. B., Dirksen, C., Bojsen-Møller, K. N., Kristiansen, V. B., Wulff, B. S., Rainteau, D., Humbert, L., Rehfeld, Jens Frederik, Holst, Jens Juul, Madsbad, Sten & Clausen, T. R., Mar 2015, In: The Journal of clinical endocrinology and metabolism. 100, 3, p. E396-406 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In nondiabetic, human immunodeficiency virus-infected patients with lipodystrophy, hepatic insulin extraction and posthepatic insulin clearance rate are decreased in proportion to insulin resistance
Haugaard, S. B., Andersen, Ove, Hansen, B. R., Andersen, U. B., Vølund, A., Iversen, J., Nielsen, J. O. & Madsbad, Sten, 2005, In: Metabolism. 54, 2, p. 171-179 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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In vivo and in vitro degradation of peptide YY3-36 to inactive peptide YY3-34 in humans
Toräng, S., Bojsen-Møller, K. N., Svane, M. S., Hartmann, Bolette, Rosenkilde, Mette, Madsbad, Sten & Holst, Jens Juul, 27 Jan 2016, In: A J P: Regulatory, Integrative and Comparative Physiology (Online). 310, 1, p. R866-R874 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inappropriate suppression of glucagon during OGTT but not during isoglycaemic i.v. glucose infusion contributes to the reduced incretin effect in type 2 diabetes mellitus
Knop, Filip Krag, Vilsbøll, T., Madsbad, Sten, Holst, Jens Juul & Krarup, T., Apr 2007, In: Diabetologia. 50, 4, p. 797-805 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inappropriate suppression of glucagon during OGTT but not during isoglycaemic i.v. glucose infusion contributes to the reduced incretin effect in type 2 diabetes mellitus
Knop, F. K., Vilsbøll, Tina, Madsbad, Sten, Holst, Jens Juul, Krarup, T., Knop, Filip Krag, Vilsbøll, Tina, Madsbad, Sten, Holst, J. M. & Krarup, T., 1 Apr 2007, In: Diabetologia. 50, 4, p. 797-805 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased Hepatic Insulin Clearance After Roux-en-Y Gastric Bypass
Bojsen-Møller, K. N., Dirksen, C., Jørgensen, N. B., Jacobsen, S. H., Hansen, D. L., Worm, Dorte, Naver, L., Kristiansen, V. B., Holst, Jens Juul & Madsbad, Sten, 22 Apr 2013, In: Journal of Clinical Endocrinology and Metabolism. 98, 6, p. E1066-E1071 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased expression of TNF-alpha, IL-6, and IL-8 in HALS: implications for reduced adiponectin expression and plasma levels.
Lihn, A. S., Richelsen, B., Pedersen, S., Haugaard, S. B., Rathje, G., Madsbad, Sten & Andersen, Ove, 2003, In: American Journal of Physiology: Endocrinology and Metabolism. 285, 5, p. E1072-80Research output: Contribution to journal › Journal article › Research › peer-review
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Increased glucose-stimulated FGF21 response to oral glucose in obese non-diabetic subjects after Roux-en-Y Gastric Bypass
Vienberg, S. G., Jacobsen, S. H., Worm, D., Hvolris, L. E., Naver, L. P. S., Almdal, Thomas Peter, Hansen, D. L., Wulff, B. S., Clausen, T. R., Madsbad, Sten, Holst, Jens Juul & Andersen, B., Jan 2017, In: Clinical Endocrinology. 86, 1, p. 156-159 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased meal-induced neurotensin response predicts successful maintenance of weight loss: Data from a randomized controlled trial
Brethvad, Annemette Overgaard, Zakariassen, Hannah Louise, Holt, Joachim, Lundgren, J. R., Jakobsen, A., Hartmann, Bolette, Lehmann, E. W., Kissow, Hannelouise, Holst, Jens Juul, Madsbad, Sten, Torekov, Signe Sørensen & Holst, Birgitte, 2023, In: Metabolism: Clinical and Experimental. 143, 8 p., 155534.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes
Larsen, Steen, Stride, N., Hey-Mogensen, M., Hansen, C. N., Andersen, J. L., Madsbad, Sten, Worm, Dorte, Helge, Jørn Wulff & Dela, Flemming, 2011, In: Diabetologia. 54, 6, p. 1427-36 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased oral sodium chloride intake in humans amplifies selectively postprandial GLP-1 but not GIP, CCK, and gastrin in plasma
Asmar, A., Cramon, P. K., Asmar, M., Simonsen, L., Sorensen, Charlotte Mehlin, Madsbad, Sten, Moro, C., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul, Hovind, P., Jensen, B. L. & Bülow, J., 2020, In: Physiological Reports. 8, 15, 11 p., e14519.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased postprandial responses of GLP-1 and GIP in patients with chronic pancreatitis and steatorrhea following pancreatic enzyme substitution.
Knop, F. K., Vilsbøll, Tina, Larsen, S., Højberg, P. V., Vølund, A., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 292, 1, p. E324-30Research output: Contribution to journal › Journal article › Research › peer-review
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Incretin hormone secretion in women with polycystic ovary syndrome: roles of obesity, insulin sensitivity, and treatment with metformin
phk294, phk294, Nilas, L., Madsbad, Sten & Holst, Jens Juul, 2009, In: Metabolism - Clinical and Experimental. 58, 5, p. 586-593Research output: Contribution to journal › Journal article › Research › peer-review
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Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus
Vilsbøll, Tina, Krarup, T., Sonne, J., Madsbad, Sten, Vølund, A., Juul, Anders, Holst, J. M. & Juul, A. G., 1 Jun 2003, In: Journal of Clinical Endocrinology and Metabolism. 88, 6, p. 2706-13 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus
Vilsbøll, T., Krarup, T., Sonne, J., Madsbad, Sten, Vølund, A., Juul, A. G. & Holst, Jens Juul, Jun 2003, In: The Journal of clinical endocrinology and metabolism. 88, 6, p. 2706-13 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Incretin-based therapies: viewpoints on the way to consensus
Nauck, M. A., Vilsbøll, Tina, Gallwitz, B., Garber, A. & Madsbad, Sten, 1 Nov 2009, In: Diabetes Care. 32 Suppl 2, p. S223-31Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of NAFLD and bariatric surgery on hepatic and adipose tissue mitochondrial biogenesis and respiration
Pedersen, J. S., Rygg, M. O., Chrøis, K., Sustarsic, E. G., Gerhart-Hines, Zach, Wever Albrechtsen, N. J., Serizawa, R. R., Kristiansen, V. B., Basse, A. L., Boilesen, Astrid Elisabeth Bruun, Olsen, B. H., Hansen, Torben, Gluud, Lise Lotte, Madsbad, Sten, Larsen, S., Bendtsen, Flemming & Dela, Flemming, 2022, In: Nature Communications. 13, 15 p., 2931.Research output: Contribution to journal › Journal article › Research › peer-review
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Instrumentalization of eating improves weight loss maintenance in obesity
Christensen, Bodil Just, Iepsen, E. P. W., Lundgren, J. R., Holm, Lotte, Madsbad, Sten, Holst, Jens Juul & Torekov, Signe Sørensen, 2017, In: Obesity Facts. 10, 6, p. 633-647 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Insufficient sleep predicts poor weight loss maintenance after one year
Bogh, A. F., Jensen, Simon Birk Kjær, Juhl, C. R., Janus, C., Sandsdal, Rasmus Michael, Lundgren, J. R., Noer, M. H., Vu, N. Q., Fiorenza, Matteo, Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2023, In: Sleep. 46, 5, 12 p., zsac295.Research output: Contribution to journal › Journal article › Research › peer-review
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Insulin analogues: have they changed insulin treatment and improved glycaemic control?
Madsbad, Sten, 2002, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 18 Suppl 1, p. 21-28 8 p.Research output: Contribution to journal › Review › Research
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Insulin resistance and glucose intolerance independently reduce the incretin effect via a beta cell defect
Jensen, D. H., Aaboe, K., Voelund, A., Henriksen, J. E., Holst, J. M., Madsbad, Sten & Krarup, T., 2010, In: Diabetologia. 53Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Insulin resistance, the metabolic syndrome, and risk of incident cardiovascular disease: a population-based study.
Jeppesen, J., Hansen, T. W., Rasmussen, S., Ibsen, H., Torp-Pedersen, C. & Madsbad, Sten, 2007, In: Journal of the American College of Cardiology. 49, 21, p. 2112-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Insulin secretion after short- and long-term low-grade free fatty acid infusion in men with increased risk of developing type 2 diabetes.
Storgaard, H., Jensen, C. B., Vaag, A. A., Vølund, A. & Madsbad, Sten, 2003, In: Metabolism. 52, 7, p. 885-894 10 p.Research output: Contribution to journal › Journal article › Research
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Insulin secretion and cellular glucose metabolism after prolonged low-grade intralipid infusion in young men
Jensen, C. B., Storgaard, H., Holst, Jens Juul, Dela, F., Madsbad, Sten & Vaag, A. A., 2003, In: Journal of Clinical Endocrinology and Metabolism. 88, 6, p. 2775-2783 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Insulin secretion and cellular glucose metabolism after prolonged low-grade intralipid infusion in young men
Jensen, C. B., Storgaard, H., Holst, Jens Juul, Dela, Flemming, Madsbad, Sten & Vaag, Allan, Jun 2003, In: The Journal of clinical endocrinology and metabolism. 88, 6, p. 2775-83 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Insulin secretion in lipodystrophic HIV-infected patients is associated with high levels of nonglucose secretagogues and insulin resistance of beta-cells.
Haugaard, S. B., Andersen, Ove, Storgaard, H., Dela, Flemming, Holst, Jens Juul, Iversen, J., Nielsen, J. O. & Madsbad, Sten, 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 287, 4, p. E677-85 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Insulin signal transduction in skeletal muscle from glucose-intolerant relatives of type 2 diabetic patients [corrected].
Storgaard, H., Song, X. M., Jensen, C. B., Madsbad, Sten, Björnholm, M., Vaag, A. & Zierath, J. R., 2001, In: Diabetes. 50, 12, p. 2770-2778 9 p.Research output: Contribution to journal › Journal article › Research
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Insulin-like growth factors, insulin-like growth factor-binding proteins, insulin-like growth factor-binding protein-3 protease, and growth hormone-binding protein in lipodystrophic human immunodeficiency virus-infected patients
Haugaard, S. B., Andersen, Ove, Hansen, B. R., Orskov, H., Andersen, U. B., Madsbad, Sten, Iversen, J. & Flyvbjerg, A., 2004, In: Metabolism. 53, 12, p. 1565-1573 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Insulinotropic effect of endogenously secreted incretins after gastric bypass and sleeve gastrectomy
Madsbad, Sten & Holst, Jens Juul, 2023, In: Obesity. 31, 11, p. 2723-2724 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Interaction of sulfonylurea and exercise on glucose homeostasis in type 2 diabetic patients
Larsen, J. J., Dela, Flemming, Madsbad, Sten, Vibe-Petersen, J. & Galbo, Henrik, 1999, In: Diabetes Care. 10, p. 1647-1654Research output: Contribution to journal › Journal article › Research › peer-review
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Intestinal sensing and handling of dietary lipids in gastric bypass-operated patients and matched controls
Martinussen, C., Dirksen, C., Bojsen-Møller, K. N., Svane, M. S., Carlsson, E. R., Hartmann, Bolette, Clausen, T. R., Veedfald, Simon, Kristiansen, V. B., Rehfeld, Jens Frederik, Hansen, Harald S., Holst, Jens Juul & Madsbad, Sten, 2020, In: American Journal of Clinical Nutrition. 111, 1, p. 28-41Research output: Contribution to journal › Journal article › Research › peer-review
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Intramyocellular triglyceride content in man, influence of sex, obesity and glycaemic control
Haugaard, Steen Bendix, Madsbad, Sten, Mu, Huiling & Vaag, Allan, 2009, In: European Journal of Endocrinology. 161, 1, p. 57-64 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Intranasal insulin therapy: the clinical realities.
Hilsted, J., Madsbad, Sten, Hvidberg, A., Rasmussen, M. H., Krarup, T., Ipsen, H., Hansen, B., Pedersen, M., Djurup, R. & Oxenbøll, B., 1995, In: Diabetologia. 38, 6, p. 680-684 5 p.Research output: Contribution to journal › Journal article › Research
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Investigating the roles of hyperglycaemia, hyperinsulinaemia and elevated free fatty acids in cardiac function in patients with type 2 diabetes via treatment with insulin compared with empagliflozin: Protocol for the HyperCarD2 randomised, crossover trial
Thirumathyam, R., Richter, Erik A., Goetze, Jens P. , Fenger, M., van Hall, Gerrit, Dixen, Ulrik, Holst, Jens Juul, Madsbad, Sten, Vejlstrup, N., Madsen, Per & Jørgensen, N. B., 2022, In: B M J Open. 12, 8, 10 p., e054100.Research output: Contribution to journal › Journal article › Research › peer-review
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Is Glycogen Synthase Kinase-3β an Ultraconserved Kernel Enzyme?
Fenger, M., Haugaard, S. B., Andersen, Ove, Madsbad, Sten, Werge, T. & Linneberg, A., 11 Dec 2009, In: Gene Expression to Genetical Genomics.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 10877
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Instrumentalization of eating improves weight loss maintenance in obesity
Research output: Contribution to journal › Journal article › Research › peer-review
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458
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Treatment with liraglutide may improve markers of CVD reflected by reduced levels of apoB
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396
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Roux-en-Y gastric bypass surgery of morbidly obese patients induces swift and persistent changes of the individual gut microbiota
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