Filip Krag Knop
Clinical Professor
Department of Clinical Medicine
Borgmester Ib Juuls Vej 1, 2730 Herlev
Member of:
Internal Medicine: Endocrinology
- Published
Near-normalization of glycaemic control with glucagon-like peptide-1 receptor agonist treatment combined with exercise in patients with type 2 diabetes
Mensberg, P., Nyby, S., Jørgensen, P. G., Storgaard, H., Jensen, M. T., Sivertsen, J., Holst, Jens Juul, Kiens, Bente, Richter, Erik A., Knop, Filip Krag & Vilsbøll, Tina, 2017, In: Diabetes, Obesity and Metabolism. 19, 2, p. 172-180 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Neurotensin secretion after Roux-en-Y gastric bypass, sleeve gastrectomy, and truncal vagotomy with pyloroplasty
Svane, M. S., Øhrstrøm, C. C., Plamboeck, A., Jørgensen, Nils Bruun, Bojsen-Møller, K. N., Dirksen, C., Martinussen, C., Vilsbøll, Tina, Hartmann, Bolette, Deacon, Carolyn F., Kristiansen, V. B., Knop, Filip Krag, Svendsen, Lars Bo, Madsbad, Sten, Holst, Jens Juul & Veedfald, Simon, 2022, In: Neurogastroenterology and Motility. 34, 1, e14210.Research output: Contribution to journal › Journal article › Research › peer-review
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New Avenues in the Regulation of Gallbladder Motility: Implications for the Use of Glucagon-Like Peptide-Derived Drugs
Gether, I. M., Nexøe-Larsen, C. & Knop, Filip Krag, 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 7, p. 2463-2472Research output: Contribution to journal › Review › Research › peer-review
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No Acute Effects of Exogenous Glucose-Dependent Insulinotropic Polypeptide on Energy Intake, Appetite, or Energy Expenditure When Added to Treatment With a Long-Acting Glucagon-Like Peptide 1 Receptor Agonist in Men With Type 2 Diabetes
Bergmann, N. C., Gasbjerg, Lærke Smidt, Heimbürger, S. M., Krogh, L. S. L., Dela, Flemming, Hartmann, Bolette, Holst, Jens Juul, Jessen, L., Christensen, Mikkel Bring, Vilsbøll, Tina, Lund, A. & Knop, Filip Krag, 2020, In: Diabetes Care. 43, 3, p. 588-596 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No changes in levels of bone formation and resorption markers following a broad-spectrum antibiotic course
Mikkelsen, K. H., Vilsbøll, Tina, Holst, Jens Juul, Hartmann, Bolette, Knop, Filip Krag & Frost, M., 2018, In: BMC Endocrine Disorders. 18, 6 p., 60.Research output: Contribution to journal › Journal article › Research › peer-review
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No cognitive-enhancing effect of GLP-1 receptor agonism in antipsychotic-treated, obese patients with schizophrenia
Ishøy, P. L., Fagerlund, Birgitte, Broberg, B. V., Bak, N., Knop, Filip Krag, Glenthøj, Birte Yding & Ebdrup, Bjørn, Jul 2017, In: Acta Psychiatrica Scandinavica. 136, 1, p. 52-62Research output: Contribution to journal › Journal article › Research › peer-review
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No detectable effect of a type 2 diabetes-associated TCF7L2 genotype on the incretin effect
Mathiesen, D. S., Bagger, J., Hansen, K. B., Junker, A. E., Plamboeck, A., Harring, S., Idorn, T., Hornum, M., Holst, Jens Juul, Jonsson, Anna Elisabet, Hansen, Torben, Vilsbøll, Tina, Lund, Asger Bach & Knop, Filip Krag, 2020, In: Endocrine Connections. 9, 12, p. 1221-1232 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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No effect of the turmeric root phenol curcumin on prednisolone-induced gluco-metabolic perturbations in men with overweight or obesity
Hellmann, P. H., Bagger, J. I., Carlander, K. R., Hansen, K. B., Forman, Julie Lyng, Størling, Joachim, Chabanova, E., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: Endocrine Connections. 12, 4, e220334.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No hypoglycemia after subcutaneous administration of glucagon-like peptide-1 in lean type 2 diabetic patients and in patients with diabetes secondary to chronic pancreatitis.
Knop, Filip Krag, Vilsbøll, Tina, Larsen, S., Madsbad, Sten, Holst, J. J. & Krarup, T., 2003, In: Diabetes Care. 26, 9, p. 2581-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Non-alcoholic fatty liver disease alters expression of genes governing hepatic nitrogen conversion
Eriksen, P. L., Vilstrup, H., Rigbolt, K., Suppli, M. P., Sørensen, M., Heebøll, S., Veidal, S. S., Knop, Filip Krag & Thomsen, K. L., 2019, In: Liver International. 39, 11, p. 2094-2101Research output: Contribution to journal › Journal article › Research › peer-review
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Nonalcoholic Fatty Liver Disease Is Prevalent in Women With Prior Gestational Diabetes Mellitus and Independently Associated With Insulin Resistance and Waist Circumference
Foghsgaard, S., Andreasen, C., Vedtofte, L., Andersen, E. S., Bahne, E., Strandberg, C., Buhl, T., Holst, Jens Juul, Svare, J. A., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Gluud, Lise Lotte, Knop, Filip Krag & Vilsbøll, Tina, Jan 2017, In: Diabetes Care. 40, 1, p. 109-116 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nonalcoholic Fatty Liver Disease in Patients with Type 2 Diabetes and Chronic Kidney Disease
Adrian, T., Hornum, Mads, Knop, Filip Krag, Almdal, Thomas Peter, Rossing, Peter, Lida, L., Heinrich, N. S., Boer, V. O., Marsman, A., Petersen, E. T., Siebner, Hartwig Roman & Feldt-Rasmussen, Bo, 2023, In: Nephron. 147, 6, p. 317–328Research output: Contribution to journal › Journal article › Research › peer-review
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Normal insulin sensitivity, glucose tolerance, gut incretin and pancreatic hormone responses in adults with atopic dermatitis
Gether, L., Thyssen, Jacob Pontoppidan, Gyldenlove, M., Hartmann, Bolette, Holst, Jens Juul, Foghsgaard, S., Vilsbøll, Tina & Knop, Filip Krag, 2020, In: Diabetes, Obesity and Metabolism. 22, 11, p. 2161-2169 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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O12.4. EFFECTS OF THE GLUCAGON-LIKE PEPTIDE-1 RECEPTOR AGONIST EXENATIDE ON BONE STATUS IN OBESE, NON-DIABETIC, ANTIPSYCHOTIC-TREATED SCHIZOPHRENIA SPECTRUM PATIENTS
Eriksson, R., Broberg, B. V., Ishoy, P. L., Bak, N., Andersen, U. B., Jørgensen, Niklas Rye, Knop, Filip Krag & Ebdrup, Bjørn, 2019, In: Schizophrenia Bulletin. 45, Suppl. 2, p. S198-S199 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
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On the role of gallbladder emptying and incretin hormones for nutrient-mediated TSH suppression in patients with type 2 diabetes
Sonne, David Peick, Lund, Asger Bach, Faber, J., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Dec 2014, In: Endocrine Connections. 3, 4, p. 193-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Once-weekly GLP-1 agonists: How do they differ from exenatide and liraglutide?
Christensen, M. & Knop, Filip Krag, 1 Apr 2010, In: Current Diabetes Reports. 10, 2, p. 124-32 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Once-weekly subcutaneous semaglutide treatment for persons with type 2 diabetes: Real-world data from a diabetes out-patient clinic
Hansen, K. B., Svendstrup, M., Lund, A., Knop, Filip Krag, Vilsbøll, Tina & drb459, drb459, 2021, In: Diabetic Medicine. 38, 10, p. e14655Research output: Contribution to journal › Review › Research › peer-review
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One Year's Treatment with the Glucagon-Like Peptide 1 Receptor Agonist Liraglutide Decreases Hepatic Fat Content in Women with Nonalcoholic Fatty Liver Disease and Prior Gestational Diabetes Mellitus in a Randomized, Placebo-Controlled Trial
Vedtofte, L., Bahne, E., Foghsgaard, S., Bagger, J. I., Andreasen, C., Strandberg, C., Gortz, P. M., Holst, Jens Juul, Gronbaek, H., Svare, J. A., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Gluud, Lise Lotte, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Journal of Clinical Medicine. 9, 10, 14 p., 3213.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oral glucose has little or no effect on appetite and satiety sensations despite a significant gastrointestinal response
Lauritsen, J. V., Bergmann, N., Junker, A. E., Gyldenløve, Mette, Skov, Lone, Gluud, Lise Lotte, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: European Journal of Endocrinology. 189, 6, p. 619-626 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Oral semaglutide 50 mg taken once per day in adults with overweight or obesity (OASIS 1): a randomised, double-blind, placebo-controlled, phase 3 trial
OASIS 1 Investigators, O. 1. I., 2023, In: The Lancet. 402, 10403, p. 705-719 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Oxyntomodulin Identified as a Marker of Type 2 Diabetes and Gastric Bypass Surgery by Mass-spectrometry Based Profiling of Human Plasma
Albrechtsen, Nicolai Jacob Wewer, Hornburg, D., Albrechtsen, Reidar, Svendsen, B., Toräng, S., Jepsen, Sara Lind, Kuhre, Rune Ehrenreich, Hansen, M., Janus, C., Floyd, A., Lund, Asger Bach, Vilsbøll, Tina, Knop, Filip Krag, drb459, drb459, Deacon, Carolyn F., Meissner, F., Mann, Matthias, Holst, Jens Juul & Hartmann, Bolette, May 2016, In: EBioMedicine. 7, p. 112-120 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Palaeolithic diet decreases fasting plasma leptin concentrations more than a diabetes diet in patients with type 2 diabetes: A randomised cross-over trial
Fontes-Villalba, M., Lindeberg, S., Granfeldt, Y., Knop, Filip Krag, Memon, A. A., Carrera-Bastos, P., Picazo, Ó., Chanrai, M., Sunquist, J., Sundquist, K. & Jönsson, T., 2016, In: Cardiovascular Diabetology. 15, 1, 10 p., 80.Research output: Contribution to journal › Journal article › Research › peer-review
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Pan-alimentary assessment of motility, luminal content, and structures: an MRI-based framework
Bertoli, D., Mark, E. B., Liao, D., Brock, C., Brock, Birgitte, Knop, Filip Krag, Krogh, K., Frøkjær, J. B. & Drewes, A. M., 2023, In: Scandinavian Journal of Gastroenterology. 58, 12, p. 1378–1390 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pancreatic Amylase and Lipase Plasma Concentrations Are Unaffected by Increments in Endogenous GLP-1 Levels Following Liquid Meal Tests
Sonne, David Peick, Vilsbøll, T. & Knop, Filip Krag, 2015, In: Diabetes Care. 38, 5, p. e71-2 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pancreatic polypeptide: A potential biomarker of glucose-dependent insulinotropic polypeptide receptor activation in vivo
Veedfald, Simon, Bergmann, N. C., Vilsbøll, Tina, Christensen, Mikkel Bring, Holst, Jens Juul & Knop, Filip Krag, May 2021, In: Diabetic Medicine Online. 38, 8, e14592.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Pancreatic polypeptide responses to isoglycemic oral and intravenous glucose in humans with and without intact vagal innervation
Veedfald, Simon, Plamboeck, A., Hartmann, Bolette, Svendsen, Lars Bo, Vilsbøll, T., Knop, Filip Krag & Holst, Jens Juul, Sep 2015, In: Peptides. 71, p. 229-31 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Parenteral nutrition impairs plasma bile acid and gut hormone responses to mixed meal testing in lean healthy men
Meessen, E. C. E., Bakker, G. J., Nieuwdorp, M., Dallinga-Thie, G. M., Kemper, E. M., Olde Damink, S. W., Romijn, J. A., Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag, Groen, A. K., Schaap, F. G. & Soeters, M. R., 2021, In: Clinical Nutrition. 40, 3, p. 1013-1021Research output: Contribution to journal › Journal article › Research › peer-review
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Patient Assessment of Family Function, Glycemic Control and Quality of Life in Adult Patients With Type 2 Diabetes and Incipient Complications
Bennich, B. B., Munch, L., Egerod, Ingrid Eugenie, Konradsen, H., Ladelund, S., Knop, Filip Krag, Vilsbøll, Tina, Røder, M. & Overgaard, D., 2019, In: Canadian Journal of Diabetes. 43, 3, p. 193-200Research output: Contribution to journal › Journal article › Research › peer-review
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Patients with psoriasis are insulin resistant
Gyldenløve, M., Storgaard, H., Holst, Jens Juul, Vilsbøll, T., Knop, Filip Krag & Skov, Lone, Apr 2015, In: Journal of the American Academy of Dermatology. 72, 4, p. 599-605 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma YKL-40 during pregnancy and gestational diabetes mellitus
Rinnov, A. R., Rathcke, C. N., Bonde, L., Vilsbøll, Tina & Knop, Filip Krag, 2015, In: Journal of Reproductive Immunology. 112, p. 68-72Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease
Niu, Lili, Geyer, P. E., Albrechtsen, Nicolai Jacob Wewer, Gluud, Lise Lotte, Santos, A., Doll, S., Treit, P. V., Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina, Junker, A., Sachs, S., Stemmer, K., Müller, T. D., Tschöp, M. H., Hofmann, S. M. & Mann, Matthias, 2019, In: Molecular Systems Biology. 15, 16 p., e8793.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma proteome profiling discovers potential biomarkers of non-alcoholic fatty liver disease
Niu, Lili, Gupta, R., Geyer, P. E., Albrechtsen, Nicolai Jacob Wewer, Gluud, Lise Lotte, Santos, A., Doll, S., Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina, Junker, A., Sachs, S., Stemmer, K., Mueller, T. D., Tschoep, M. H., Hofmann, S. M. & Mann, Matthias, Aug 2019, In: Molecular & Cellular Proteomics. 18, 8, p. S71 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
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Positioning Glucagon-like-peptide-1-based Treatment within an Optimal Manegement Regimen for Type 2 Diabetes
Hansen, K. B., Vilsboll, T. & Knop, Filip Krag, 2008, In: European Journal of Endocrinology. Supplement. 4, p. 44-47 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Postprandial Plasma Concentrations of Individual Bile Acids and FGF-19 in Patients With Type 2 Diabetes
Sonne, David Peick, van Nierop, F. S., Kulik, W., Soeters, M. R., Vilsbøll, Tina & Knop, Filip Krag, Aug 2016, In: Endocrinology. 101, 8, p. 3002-3009 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Postprandial Plasma Concentrations of ProANP in Patients with Type 2 Diabetes and Healthy Controls
Sonne, D. P., Terzic, D., Knop, Filip Krag & Goetze, Jens P. , May 2017, In: Clinical Chemistry. 63, 5, p. 1040-1041 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Postprandial effects of individual and combined GIP and GLP-1 receptor antagonism in healthy subjects
Gasbjerg, Lærke Smidt, Helsted, M. M., wbf943, wbf943, Lanng, A. R., Stensen, S., Jakobsen, M. H., Hartmann, Bolette, Christensen, Mikkel Bring, Holst, Jens Juul, Vilsbøll, Tina, Rosenkilde, M. M. & Knop, Filip Krag, 2018, In: Diabetologia. 61, S1, p. S246-S246 503.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Postprandial gallbladder emptying in patients with type 2 diabetes: potential implications for bile-induced secretion of glucagon-like peptide 1
Sonne, David Peick, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Oct 2014, In: European Journal of Endocrinology. 171, 4, p. 407-419 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Postprandial gut hormone responses and glucose metabolism in cholecystectomized patients
Sonne, D. P., Hare, K. J., Martens, P., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 15 Feb 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 304, 4, p. G413-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Postprandial incretin and islet hormone responses and dipeptidyl-peptidase 4 enzymatic activity in patients with maturity onset diabetes of the young
Østoft, S. H., Bagger, J. I., Hansen, Torben, Hartmann, Bolette, Pedersen, Oluf Borbye, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 1 Aug 2015, In: European Journal of Endocrinology. 173, 2, p. 205-215 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Postprandial prolactin suppression appears absent in antipsychotic-treated male patients
Coello, K., Broberg, B. V., Bak, N., Madsen, A., Mortensen, H. B., Søgaard, B., Szecsi, P. B., Knop, Filip Krag, Lublin, H. & Ebdrup, B. H., Oct 2015, In: Psychoneuroendocrinology. 60, p. 1-6 6 p.Research output: Contribution to journal › Letter › Research › peer-review
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Postprandial responses of incretin and pancreatic hormones in non-diabetic patients with end-stage renal disease
Idorn, T., Knop, Filip Krag, Jørgensen, M., Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Jan 2014, In: Nephrology, Dialysis, Transplantation. 29, 1, p. 119-27 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Preclinical discovery and development of colesevelam for the treatment of type 2 diabetes
Nerild, H. H., Christensen, Mikkel Bring, Knop, Filip Krag & Brønden, A., 2018, In: Expert Opinion on Drug Discovery. 13, 12, p. 1161-1167 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prediabetes Defined by First Measured HbA1c Predicts Higher Cardiovascular Risk Compared With HbA1c in the Diabetes Range: A Cohort Study of Nationwide Registries
Yahyavi, S. K., Snorgaard, O., Knop, Filip Krag, Schou, Morten, Lee, C., Selmer, C., Gislason, Gunnar Hilmar, Torp-Pedersen, Christian, Blomberg Jensen, M. & Nissen Bonde, A., 2021, In: Diabetes Care. 44, 12, p. 2767-2774 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Predictors of Improvement in Quality of Life When Treating Hypothyroidism
Medici, B. B., Lerche la Cour, J., Knop, Filip Krag, Krakauer, M., Michaelsson, L. F., Faber, Jens, Watt, Torquil & Nygaard, Birte, 2021, In: Journal of Thyroid Research. 2021, 7 p., 5577217.Research output: Contribution to journal › Journal article › Research › peer-review
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Pregnancy loss is associated with type 2 diabetes: a nationwide case-control study
Egerup, P., Mikkelsen, A. P., Kolte, A. M., Westergaard, D., Rasmussen, S., Knop, Filip Krag, Lidegaard, Øjvind & Nielsen, Henriette Svarre, 2020, In: Diabetologia. 63, 8, p. 1521-1529Research output: Contribution to journal › Journal article › Research › peer-review
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Premature explantation of an EndoBarrier gastrointestinal liner because of sleeve invagination
Rohde, U., Federspiel, C. A., Vilmann, Peter, Friis, S. U., Langholz, E., Vilsbøll, Tina & Knop, Filip Krag, 2015, In: Endoscopy. 47 , Suppl 1 , p. E275-6 2 p.Research output: Contribution to journal › Letter › Research › peer-review
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Preserved inhibitory potency of GLP-1 on glucagon secretion in type 2 diabetes mellitus
Hare, K. J., Knop, Filip Krag, Asmar, M., Madsbad, Sten, Deacon, Carolyn F., Holst, Jens Juul & Vilsbøll, Tina, 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 12, p. 4679-87 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Preserved postprandial GLP-1 and GIP responses in patients with maturity onset diabetes of the young
Bagger, J. I., Ostoft, S. H., Hansen, T., Pedersen, O., Holst, Jens Juul, Knop, Filip Krag & Vilsboll, T., 2013, In: Diabetologia. 56, p. S152-S152Research output: Contribution to journal › Journal article › Research › peer-review
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Prevalence and predictive features of metabolic dysfunction-associated steatotic liver disease in type 1 diabetes
Fuhri Snethlage, C. M., Meijnikman, A. S., Mak, A. L., Rampanelli, E., Voermans, B., Callender, C. A. K., De Groen, P., Roep, B. O., Van Raalte, D. H., Knop, Filip Krag, Holleboom, A. G., Nieuwdorp, M. & Hanssen, N. M. J., 2024, In: European Journal of Endocrinology. 190, 5, p. 391-400 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prevalence of non-alcoholic fatty liver disease in patients with chronic kidney disease: a cross-sectional study
Adrian, T., Sørensen, I. M. H., Knop, Filip Krag, Bro, S., Ballegaard, E. L. F., Nordestgaard, Børge, Fuchs, A., Kofoed, Klaus Fuglsang, Kühl, J. T., Sigvardsen, P. E., Hornum, Mads & Feldt-Rasmussen, Bo, 2022, In: Nephrology Dialysis Transplantation. 37, 10, p. 1927-1934 gfab266.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 40100368
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L-cell Differentiation Is Induced by Bile Acids Through GPBAR1 and Paracrine GLP-1 and Serotonin Signaling
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Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease
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Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production
Research output: Contribution to journal › Journal article › Research › peer-review
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