Sten Madsbad
Clinical Professor
Department of Clinical Medicine
Kettegård Allé 30, 2650 Hvidovre
Member of:
Internal Medicine: Endocrinology
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Preoperative High-Dose Methylprednisolone and Glycemic Control Early After Total Hip and Knee Arthroplasty: A Randomized, Double-Blind, Placebo-Controlled Trial
Lindberg-Larsen, V., Kehlet, Henrik, Bagger, J. & Madsbad, Sten, 2018, In: Anesthesia and Analgesia. 127, 4, p. 906-913 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Preserved inhibitory potency of GLP-1 on glucagon secretion in type 2 diabetes mellitus
Hare, K. J., Knop, Filip Krag, Asmar, M., Madsbad, Sten, Deacon, Carolyn F., Holst, Jens Juul & Vilsbøll, Tina, 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 12, p. 4679-87 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Primary weight loss failure after Roux-en-Y gastric bypass is characterized by impaired gut-hormone mediated regulation of food intake
Bojsen-Møller, Kirstine Nyvold, Svane, M. S., Martinussen, C., Dirksen, Carsten Moro, Jørgensen, Nils Bruun, Jensen, Jens-Erik Beck, Jensen, Christian Zinck, Torekov, Signe Sørensen, Kristiansen, V. B., Rehfeld, Jens Frederik, Bork-Jensen, J., Grarup, Niels, Hansen, Torben, Hartmann, Bolette, Holst, Jens Juul & Madsbad, Sten, 2023, In: International Journal of Obesity. 47, 11, p. 1143-1151 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proglucagon products in plasma of noninsulin-dependent diabetics and nondiabetic controls in the fasting state and after oral glucose and intravenous arginine
Ørskov, Cathrine, Jeppesen, J., Madsbad, Sten & Holst, Jens Juul, Feb 1991, In: The Journal of Clinical Investigation. 87, 2, p. 415-23 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pros and cons of Roux en-Y gastric bypass surgery in obese patients with type 2 diabetes
Justinussen, T., Madsbad, Sten, Holst, Jens Juul & Bojsen-Moller, K. N., 2019, In: Expert Review of Endocrinology & Metabolism. 14, 4, p. 243-257Research output: Contribution to journal › Review › Research › peer-review
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Proteomics reveals the effects of sustained weight loss on the human plasma proteome
Geyer, P. E., Albrechtsen, Nicolai Jacob Wewer, Tyanova, S., Grassl, N., Iepsen, E. P. W., Lundgren, J., Madsbad, Sten, Holst, Jens Juul, Torekov, Signe Sørensen & Mann, Matthias, 22 Dec 2016, In: Molecular Systems Biology. 12, 16 p., 901.Research output: Contribution to journal › Journal article › Research › peer-review
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Protocol for a randomised controlled trial of the combined effects of the GLP-1 receptor agonist liraglutide and exercise on maintenance of weight loss and health after a very low-calorie diet
Jensen, Simon Birk Kjær, Lundgren, J. R., Janus, C., Juhl, C. R., Olsen, L. M., Rosenkilde, M., Holst, Jens Juul, Stallknecht, Bente Merete, Madsbad, Sten & Torekov, Signe Sørensen, 2019, In: BMJ Open. 9, 11, 10 p., e031431.Research output: Contribution to journal › Journal article › Research › peer-review
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Quality of life, patient satisfaction, and cardiovascular outcomes of the randomised 2 x 3 factorial Copenhagen insulin and Metformin therapy (CIMT) trial – A detailed statistical analysis plan
Olsen, M. H., Almdal, Thomas Peter, Madsbad, Sten, Ovesen, C., Gluud, C., Sneppen, S. B., Breum, Leif, Hedetoft, C., Krarup, T., Lundby-Christensen, L., Mathiesen, Elisabeth, Røder, M. E., drb459, drb459, Wiinberg, N. & Jakobsen, J. C., 2023, In: Contemporary Clinical Trials Communications. 33, 101095.Research output: Contribution to journal › Journal article › Research › peer-review
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Quantification of beta-cell function during IVGTT in Type II and non-diabetic subjects: assessment of insulin secretion by mathematical methods.
Kjems, L. L., Vølund, A. & Madsbad, Sten, 2001, In: Diabetologia. 44, 10, p. 1339-1348 10 p.Research output: Contribution to journal › Journal article › Research
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Randomized controlled trial of Tesomet for weight loss in hypothalamic obesity
Huynh, K., Klose, M., Krogsgaard, K., Drejer, J., Byberg, Sarah, Madsbad, Sten, Magkos, Faidon, Aharaz, A., Edsberg, B., Tfelt-Hansen, Jacob, Astrup, A. & Feldt-Rasmussen, Ulla, 2022, In: European Journal of Endocrinology. 186, 6, p. 687-700 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reduced carbohydrate and increased protein and fat during weight loss improve the atherogenic lipid profile in type 2 diabetes
Thomsen, M. N., Skytte, M. J., Samkani, A., Astrup, A., Frystyk, J., Chabanova, E., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Thomsen, Henrik S., Walzem, R. L., Krarup, T. & Haugaard, Steen Bendix, 2021, In: Diabetologia. 64, SUPPL 1, p. 60-60 109.Research output: Contribution to journal › Conference abstract in journal › Research
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Reduced carbohydrate and increased protein and fat in the diet augment the positive effect of weight loss on glucose control in type 2 diabetes patients
Thomsen, M. N., Skytte, M. J., Samkani, A., Carl, M. H., Weber, P., Astrup, A., Larsen, T. M., Frystyk, J., Holst, Jens Juul, Hartmann, Bolette, Thomsen, Henrik S., Chabanova, E., Madsbad, Sten, Haugaard, Steen Bendix & Krarup, T., 2020, In: Diabetologia. 63, Suppl. 1, p. S295-S296 614.Research output: Contribution to journal › Conference abstract in journal › Research
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Reduced incretin effect in type 2 diabetes: cause or consequence of the diabetic state?
Knop, F. K., Vilsbøll, Tina, Højberg, P. V., Larsen, S., Madsbad, Sten, Vølund, A., Holst, Jens Juul & Krarup, T., 2007, In: Diabetes. 56, 8, p. 1951-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reduced postprandial concentrations of intact biologically active glucagon-like peptide 1 in type 2 diabetic patients
Vilsbøll, Tina, Krarup, T., Deacon, C. F., Madsbad, Sten & Holst, J. M., 1 Mar 2001, In: Diabetes. 50, 3, p. 609-613 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reduced skeletal muscle mitochondrial respiration and improved glucose metabolism in nondiabetic obese women during a very low calorie dietary intervention leading to rapid weight loss
Rabøl, R., Svendsen, P. F., Skovbro, M., Boushel, R., Haugaard, S. B., Schjerling, P., Schrauwen, P., Hesselink, M. K. C., Nilas, L., Madsbad, S., Dela, F., Rabøl, R., Svendsen, P. F., Skovbro, M., Boushel, R. C., Haugaard, S. B., Schjerling, P., Schrauwen, P., Hesselink, M. K. C., Nilas, L. & 2 others, , 2009, In: Metabolism - Clinical and Experimental. 58, 8, p. 1145-52 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reduction in cardiovascular risk factors and insulin dose, but no beta-cell regeneration 1 year after Roux-en-Y gastric bypass in an obese patient with type 1 diabetes: a case report
Dirksen, C., Jacobsen, S. H., Bojsen-Møller, K. N., Jørgensen, N. B., Naver, L. S., Hvolris, L. E., Worm, Dorte, Madsbad, Sten, Holst, Jens Juul & Hansen, D. L., 7 Dec 2013, In: Obesity Research & Clinical Practice. 7, 4, p. e269-74 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reduction of insulinotropic properties of GLP-1 and GIP after glucocorticoid-induced insulin resistance
Eriksen, M., Jensen, D. H., Tribler, S., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2015, In: Diabetologia. 58, 5, p. 920-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reduction of oxidative stress on DNA and RNA in obese patients after Roux-en-Y gastric bypass surgery-An observational cohort study of changes in urinary markers
Carlsson, E. R., Fenger, M., Henriksen, T., Kjaer, L. K., Worm, Dorte, Hansen, D. L., Madsbad, Sten & Poulsen, Henrik Enghusen, 2020, In: PLoS ONE. 15, 12 December, e0243918.Research output: Contribution to journal › Journal article › Research › peer-review
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Regional anatomic differences in skeletal muscle mitochondrial respiration in type 2 diabetes and obesity
Rabøl, R., Larsen, Steen, Højberg, P. M. V., Almdal, Thomas Peter, Boushel, R. C., Haugaard, Steen Bendix, Andersen, J. L., Madsbad, Sten & Dela, Flemming, 1 Feb 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 2, p. 857-63 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Relationship Between Two Common Lipoprotein Lipase Variants and the Metabolic Syndrome and Its Individual Components
Vishram, J. K. K., Hansen, T. W., Torp-Pedersen, C., Madsbad, Sten, Jørgensen, T., Fenger, M., Lyngbæk, S. & Jeppesen, J., Nov 2016, In: Metabolic Syndrome and Related Disorders. 14, 9, p. 442-448 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Relationship between Optimum Mini‐doses of Glucagon and Insulin Levels when Treating Mild Hypoglycaemia in Patients with Type 1 Diabetes: A Simulation Study
Ranjan, A., Wendt, S. L., Schmidt, S., Madsbad, Sten, Holst, Jens Juul, Madsen, H., Knudsen, C. B., Jørgensen, J. B. & Nørgaard, Kirsten, 2018, In: Basic & Clinical Pharmacology & Toxicology. 122, 3, p. 322-330Research output: Contribution to journal › Journal article › Research › peer-review
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Relationship between common lipoprotein lipase gene sequence variants, hyperinsulinemia, and risk of ischemic heart disease: A population-based study
Jeppesen, J., Hansen, Tine Willum, Torp-Pedersen, Christian, Madsbad, Sten, Ibsen, H., Jørgensen, T. & Fenger, M., 1 Aug 2010, In: Atherosclerosis. 211, 2, p. 506-11 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Remission af type 2-diabetes efter gastric bypass-kirurgi: et medicinsk mysterium?
Jacobsen, S., Hansen, D. L., Worm, Dorte, Madsbad, Sten, Hvolris, L. E., Naver, L. P. S. & Holst, Jens Juul, 2009, In: Behandlerbladet. p. 20-29 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Renal Extraction and Acute Effects of Glucagon-like peptide-1 on Central and Renal Hemodynamics in Healthy Men
Asmar, A., Simonsen, L., Asmar, M., Madsbad, Sten, Holst, Jens Juul, Frandsen, E., Moro, C., Jonassen, Thomas & Bülow, J., 15 Apr 2015, In: American Journal of Physiology: Endocrinology and Metabolism. 308, 8, p. E641-E649 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reply - Letter to the editor - On carbohydrate restriction and health-related quality of life and cognition in type 2 diabetes
Jensen, N. J., Thomsen, M. N., Skytte, M. J., Astrup, A., Holst, Jens Juul, Madsbad, Sten, Magkos, Faidon, Miskowiak, Kamilla, Haugaard, Steen Bendix, Krarup, T. & Rungby, Jørgen, 2022, In: Clinical Nutrition. 41, 9, p. 2061-2062 2 p.Research output: Contribution to journal › Comment/debate › Research
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Responses of gut and pancreatic hormones, bile acids, and fibroblast growth factor-21 differ to glucose, protein, and fat ingestion after gastric bypass surgery
Jensen, C. Z., Bojsen-Møller, K. N., Svane, M. S., Holst, L. M., Hermansen, K., Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Kristiansen, V. B., Rehfeld, Jens Frederik, Clausen, T. R., Holst, Jens Juul & Madsbad, Sten, 2020, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 318, 4, p. G661-G672 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Restoration of the insulinotropic effect of glucose-dependent insulinotropic polypeptide contributes to the antidiabetic effect of dipeptidyl peptidase-4 inhibitors
Aaboe, K., Akram, S., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., Jan 2015, In: Diabetes, Obesity and Metabolism. 17, 1, p. 74-81 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Retinal characteristics during 1 year of insulin pump therapy in type 1 diabetes: a prospective, controlled, observational study
Klefter, O. N., Hommel, E., Munch, I. C., Nørgaard, Kirsten, Madsbad, Sten & Larsen, Michael, Sep 2016, In: Acta Ophthalmologica. 94, 6, p. 540-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Retinal function in relation to improved glycaemic control in type 1 diabetes
Holfort, S. K., Nørgaard, Kirsten, Jackson, G., Hommel, E., Madsbad, Sten, Munch, I. C., Klemp, K., Sander, B. & Larsen, Michael, 2011, In: Diabetologia. 54, 7, p. 1853-61 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Review of head-to-head comparisons of glucagon-like peptide-1 receptor agonists
Madsbad, Sten, Apr 2016, In: Diabetes, Obesity and Metabolism. 18, 4, p. 317-32 16 p.Research output: Contribution to journal › Review › Research › peer-review
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Roux-en-Y gastric bypass surgery does not preserve energy expenditure in humans
Schmidt, J. B., Gunvald, L. E., Gregersen, N. T., Pedersen, S. D., Holst, Jens Juul, Hansen, D. L., Worm, Dorte, Madsbad, Sten, Astrup, A. & Sjödin, Anders Mikael, 2012, In: Regulatory Peptides. 177, suppl.1, p. S32 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Roux-en-Y gastric bypass surgery of morbidly obese patients induces swift and persistent changes of the individual gut microbiota
Palleja, A., Kashani, A., Allin, K. H., Nielsen, T., Zhang, C., Li, Y., Brach, Thorsten, Liang, S., Feng, Q., Jørgensen, N. B., Bojsen-Møller, K. N., Dirksen, C., Burgdorf, Kristoffer Sølvsten, Holst, Jens Juul, Madsbad, Sten, Wang, J., Pedersen, Oluf Borbye, Hansen, Torben & Arumugam, Mani, 2016, In: Genome Medicine. 8, 13 p., 67.Research output: Contribution to journal › Journal article › Research › peer-review
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S100A8/A9 (Calprotectin), Interleukin-6, and C-Reactive Protein in Obesity and Diabetes before and after Roux-en-Y Gastric Bypass Surgery
Lylloff, L., Bathum, L., Madsbad, Sten, Grundtvig, J. L. G., Nordgaard-Lassen, I. & Fenger, M., 2017, In: Obesity Facts. 10, 4, p. 386-395 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Secretin release after Roux-en-Y gastric bypass reveals a population of glucose-sensitive S cells in distal small intestine
Modvig, Ida Marie, Andersen, Daniel Bjørklund, Grunddal, Kaare Villum, Kuhre, Rune Ehrenreich, Martinussen, C., Christiansen, Charlotte Bayer, Ørskov, Cathrine, Larraufie, P., Kay, R. G., Reimann, F., Gribble, F. M., Hartmann, Bolette, Bojsen-Moller, K. N., Madsbad, Sten, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2020, In: International Journal of Obesity. 44, 9, p. 1859-1871Research output: Contribution to journal › Journal article › Research › peer-review
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Semaglutide seems to be more effective the other GLP-1Ras
Holst, Jens Juul & Madsbad, Sten, Dec 2017, In: Annals of Translational Medicine. 5, 24, 5 p., 505.Research output: Contribution to journal › Comment/debate › Research
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Separate effects of glucagon like peptide-2 (GLP-2) and glucose-dependent insulinotropic polypeptide (GIP) on bone remodelling
Skov-Jeppesen, Kirsa, Svane, M., Martinussen, C., Gabe, M., Gasbjerg, Lærke Smidt, Madsbad, Sten, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2018, In: Diabetologia. 61, S1, p. S245-S245 501.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Sex and muscle structural lipids in obese subjects - an impact on insulin action?
Haugaard, S. B., Vaag, Allan, Høy, C. & Madsbad, Sten, 2008, In: European Journal of Clinical Investigation. 38, 7, p. 494-501 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Short-term effects of a low carbohydrate diet on glycaemic variables and cardiovascular risk markers in patients with type 1 diabetes: A randomized open-label crossover trial
Ranjan, A., Schmidt, S., Damm-Frydenberg, C., Holst, Jens Juul, Madsbad, Sten & Nørgaard, Kirsten, Oct 2017, In: Diabetes, Obesity and Metabolism. 19, 10, p. 1479-1484Research output: Contribution to journal › Journal article › Research › peer-review
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Skeletal Muscle Mitochondrial Function in Polycystic Ovarian Syndrome
Rabøl, R., Svendsen, P. M., Skovbro, M., Boushel, R. C., Schjerling, Peter, Nilas, L., Madsbad, Sten & Dela, Flemming, 2011, In: European Journal of Endocrinology. 165, 4, p. 631-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Skeletal muscle insulin signaling defects downstream of PI3K at the level of Akt are associated with impaired non-oxidative glucose disposal in HIV-lipodystrophy
Haugaard, S. B., Andersen, Ove, Madsbad, Sten, Frøsig, C., Iversen, J., Nielsen, J. O. & Wojtaszewski, J. F., 2005, In: Diabetes. 12, 54, p. 3474-83Research output: Contribution to journal › Journal article › Research › peer-review
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Skeletal muscle insulin signaling defects downstream of phosphatidylinositol 3-kinase at the level of akt are associated with impaired nonoxidative glucose disposal in HIV lipodystrophy
Haugaard, S. B., Andersen, O., Madsbad, Sten, Frøsig, C., Iversen, J., Nielsen, J. O. & Wojtaszewski, Jørgen F P, 2005, In: Diabetes. 54, 12, p. 3474-83 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Skeletal muscle structural lipids improve during weight-maintenance after a very low calorie dietary intervention
Haugaard, Steen Bendix, Vaag, Allan, Mu, Huiling & Madsbad, Sten, 2009, In: Lipids in Health and Disease. 8, p. 34 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Soluble urokinase plasminogen activator receptor, C-reactive protein and triglyceride are associated with heart rate variability in non-diabetic Danes
Intzilakis, T., Hartmann, G., Mouridsen, M. R., Eugen-Olsen, J., Kumarathurai, P., Madsbad, Sten, Almdal, Thomas Peter, Haugaard, Steen Bendix & Sajadieh, A., 2013, In: European Journal of Clinical Investigation. 43, 5, p. 457-468 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Sperm count is increased by diet-induced weight loss and maintained by exercise or GLP-1 analogue treatment: a randomized controlled trial
Andersen, E., Juhl, C. R., Kjøller, E. T., Lundgren, J. R., Janus, C., Dehestani, Y., Saupstad, M., Ingerslev, L. R., Duun, O. M., Jensen, Simon Birk Kjær, Holst, Jens Juul, Stallknecht, Bente Merete, Madsbad, Sten, Torekov, Signe Sørensen & Barrès, Romain, May 2022, In: Human Reproduction. 37, 7, p. 1414–1422 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Steroid-induced insulin resistance and impaired glucose tolerance are both associated with a progressive decline of incretin effect in first-degree relatives of patients with type 2 diabetes
Jensen, D. H., Aaboe, K., Henriksen, J. E., Vølund, A., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2012, In: Diabetologia. 55, 5, p. 1406-16 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Studies of association between LPIN1 variants and common metabolic phenotypes among 17,538 Danes
Burgdorf, K. S., Sandholt, C. H., Sparsø, T., Andersen, G., Witte, D. R., Jørgensen, T., Sandbaek, A., Lauritzen, T., Sørensen, Thorkild I.A., Madsbad, Sten, Hansen, Torben & Pedersen, Oluf Borbye, 1 Jul 2010, In: European Journal of Endocrinology. 163, 1, p. 81-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7,088 Danish whites
Sparsø, T., Hussain, M. S., Borch-Johnsen, K., Jørgensen, T., Madsbad, Sten, Hansen, Torben, Pedersen, Oluf Borbye & Andersen, G., 2007, In: Molecular Genetics and Metabolism. 92, 3, p. 278-282 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Studies of the Association of Arg72Pro of Tumor Suppressor Protein p53 with Type 2 Diabetes in a Combined Analysis of 55,521 Europeans
Burgdorf, K. S., Grarup, Niels, Justesen, Johanne Marie, Harder, M. N., Witte, D. R., Jørgensen, T., Sandbæk, A., Lauritzen, T., Madsbad, Sten, Hansen, Torben, DIAGRAM Consortium, D. C. & Pedersen, Oluf Borbye, 2011, In: P L o S One. 6, 1, p. e15813 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Studies of the Gly482Ser polymorphism of the peroxisome proliferator-activated receptor gamma coactivator 1alpha (PGC-1alpha) gene in Danish subjects with the metabolic syndrome
Ambye, L., Rasmussen, S., Fenger, M., Jørgensen, T., Borch-Johnsen, K., Madsbad, Sten & Urhammer, S., 2005, In: Diabetes Research and Clinical Practice. 67, 2, p. 175-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Study rationale and design of the CIMT trial: the Copenhagen Insulin and Metformin Therapy trial
Lundby Christensen, L., Almdal, T., Boesgaard, T., Breum, L., Dunn, E., Gade-Rasmussen, B., Gluud, C., Hedetoft, C., Jarloev, A., Jensen, T., Krarup, T., Johansen, L. B., Lund, S. S., Madsbad, S., Mathiesen, E., Moelvig, J., Nielsen, F., Perrild, H., Pedersen, O., Roeder, M. & 31 others, , 2009, In: Diabetes, Obesity and Metabolism. 11, 4, p. 315-22 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 10877
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Instrumentalization of eating improves weight loss maintenance in obesity
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Treatment with liraglutide may improve markers of CVD reflected by reduced levels of apoB
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Roux-en-Y gastric bypass surgery of morbidly obese patients induces swift and persistent changes of the individual gut microbiota
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