Filip Krag Knop
Clinical Professor
Department of Clinical Medicine
Borgmester Ib Juuls Vej 1, 2730 Herlev
Member of:
Internal Medicine: Endocrinology
- 2018
- Published
No changes in levels of bone formation and resorption markers following a broad-spectrum antibiotic course
Mikkelsen, K. H., Vilsbøll, Tina, Holst, Jens Juul, Hartmann, Bolette, Knop, Filip Krag & Frost, M., 2018, In: BMC Endocrine Disorders. 18, 6 p., 60.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Management of Patients with Type 2 Diabetes Shared between a Specialized Outpatient Clinic and General Practice Was Noninferior to Mono Management in a Specialized Outpatient Clinic—A Prospective, Randomized, Noninferiority Trial
Munch, L., Bennich, B. B., Overgaard, D., Konradsen, Hanne, Middelfart, H. V., Kaarsberg, N., Knop, Filip Krag, Vilsbøll, Tina & Røder, M., 2018, In: Diabetes. 67, Supplement 1, 6-OR.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Tværsektorielt samarbejde ved behandling af patienter med type 2-diabetes
Munch, L., Røder, M. E., Rasmussen, I. H., Middelfart, H., Kaarsberg, N., Bennich, B., Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Ugeskrift for Laeger. 180, 8, p. 690-693Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preclinical discovery and development of colesevelam for the treatment of type 2 diabetes
Nerild, H. H., Christensen, Mikkel Bring, Knop, Filip Krag & Brønden, A., 2018, In: Expert Opinion on Drug Discovery. 13, 12, p. 1161-1167 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of liraglutide on gallbladder emptying: A randomized, placebo-controlled trial in adults with overweight or obesity
Nexoe-Larsen, C. C., Sorensen, P. H., Hausner, H., Agersnap, M., Baekdal, M., Bronden, A., Gustafsson, L. N., Sonne, David Peick, Vedtofte, L., Vilsbøll, Tina & Knop, Filip Krag, 2018, In: Diabetes, Obesity and Metabolism. 20, 11, p. 2557-2564Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Recovery of gut microbiota of healthy adults following antibiotic exposure
Palleja, A., Mikkelsen, K. H., Forslund, S. K., Kashani, A., Allin, K. H., Nielsen, T., Hansen, T. H., Liang, S., Feng, Q., Zhang, C., Pyl, P. T., Coelho, L. P., Yang, H., Wang, J., Typas, A., Nielsen, M. F., Nielsen, H. B., Bork, P., Wang, J., Vilsbøll, T. & 4 others, , Nov 2018, In: Nature Microbiology. 3, 11, p. 1255-1265 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hemodynamic Effects of Glucagon: A Literature Review
Petersen, K. M., Bogevig, S., Holst, Jens Juul, Knop, Filip Krag & Christensen, Mikkel Bring, 2018, In: Journal of Clinical Endocrinology & Metabolism. 103, 5, p. 1804-1812Research output: Contribution to journal › Review › Research › peer-review
- Published
Response to Letter to the Editor: "Hemodynamic Effects of Glucagon: A Literature Review"
Petersen, K. M., Bøgevig, S., Holst, Jens Juul, Knop, Filip Krag & Christensen, Mikkel Bring, 2018, In: The Journal of clinical endocrinology and metabolism. 103, 12, p. 4480-4481 2 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Cholecystokinin secretion is suppressed by glucagon-like peptide-1: clue to the mechanism of the adverse gallbladder events of GLP-1-derived drugs
Rehfeld, Jens Frederik, Knop, Filip Krag, Asmar, A., Madsbad, Sten, Holst, Jens Juul & Asmar, M., 2018, In: Scandinavian Journal of Gastroenterology. 53, 12, p. 1429-1432Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diagnostik og behandling af maturity onset diabetes of the young type 3
Rose, K., Christensen, A. S., Storgaard, H., Hædersdal, S., Hansen, Torben, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Ugeskrift for Laeger. 180, 6 p., V06170502.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Future Perspectives on GLP-1 Receptor Agonists and GLP-1/glucagon Receptor Co-agonists in the Treatment of NAFLD
Seghieri, M., Christensen, A. S., Andersen, A., Solini, A., Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Frontiers in Endocrinology. 9, p. 1-10 649.Research output: Contribution to journal › Review › Research › peer-review
- Published
FGF21, a liver hormone that inhibits alcohol intake in mice, increases in human circulation after acute alcohol ingestion and sustained binge drinking at Oktoberfest
Søberg, S., Andersen, E. S., Dalsgaard, N. B., Jarlhelt, I., Hansen, N. L., Hoffmann, N., Vilsbøll, Tina, Chenchar, A., Jensen, M., Grevengoed, Trisha Jean, Trammell, Sam, Knop, Filip Krag & Gillum, M. P., 2018, In: Molecular Metabolism. 11, p. 96-103 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Duodenal L cell density correlates with features of metabolic syndrome and plasma metabolites
Van Baar, A. C. G., Prodan, A., Wahlgren, C. D., Poulsen, Steen Seier, Knop, Filip Krag, Groen, A. K., Bergman, J. J., Nieuwdorp, M. & Levin, E., 2018, In: Endocrine Connections. 7, 5, p. 673-680Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ghrelin secretion in humans - a role for the vagus nerve?
Veedfald, Simon, Plamboeck, A., Hartmann, Bolette, Vilsbøll, Tina, Knop, Filip Krag, Deacon, Carolyn F., Svendsen, Lars Bo & Holst, Jens Juul, Jun 2018, In: Neurogastroenterology and Motility. 30, 6, e13295.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence of a liver-alpha cell axis in humans: hepatic insulin resistance attenuates relationship between fasting plasma glucagon and glucagonotropic amino acids
Albrechtsen, Nicolai Jacob Wewer, Færch, K., Jensen, T. M., Witte, D. R., Pedersen, Jens, Mahendran, Y., Jonsson, Anna Elisabet, Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Torekov, Signe Sørensen, Lauritzen, T., Pedersen, Oluf Borbye, Knop, Filip Krag, Hansen, Torben, Jørgensen, M. E., Vistisen, D. & Holst, Jens Juul, 2018, In: Diabetologia. 61, 3, p. 671-680Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyperglucagonemia correlates with plasma levels of non-branched-chain amino acids in patients with liver disease independent of type 2 diabetes
Albrechtsen, Nicolai Jacob Wewer, Junker, A. E., Christensen, M., Hædersdal, S., Wibrand, F., Lund, A. M., Galsgaard, Katrine Douglas, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 314, 1, p. G91-G96Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production
Albrechtsen, N. J. W., Kuhre, R. E., Hornburg, D., Jensen, C. Z., Hornum, M., Dirksen, C., Svane, M., Gasbjerg, L. S., Jorgensen, N. B., Gabe, M. N., Balk-Moller, E., Albrechtsen, R., Winther-Sorensen, M., Galsgaard, K. D., Meissner, F., Jorsal, T., Lund, A., Vilsboll, T., Eliasen, R., Bojsen-Moller, K. N. & 9 others, , Nov 2017, In: Cell Reports. 21, 6, p. 1452-1460Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Short-acting glucagon-like peptide-1 receptor agonists as add-on to insulin therapy in type 1 diabetes: A review
Albèr, A., Brønden, A. & Knop, Filip Krag, 2017, In: Diabetes, Obesity and Metabolism. 19, 7, p. 915-925Research output: Contribution to journal › Review › Research › peer-review
- Published
Adult atopic dermatitis and the risk of type 2 diabetes
Andersen, Y. M. F., Egeberg, A., Gislason, Gunnar Hilmar, Skov, Lone, Knop, Filip Krag & Thyssen, Jacob Pontoppidan, Mar 2017, In: The Journal of allergy and clinical immunology. 139, 3, p. 1057-1059 3 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Increased liver fat content in totally pancreatectomised patients
Bagger, J. I., Lund, A. B., Albrechtsen, Nicolai Jacob Wewer, Christensen, M., Grøndahl, M. F., Hansen, C. P., Storkholm, J., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Diabetologia. 60, S1, p. S572-S573Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Supportive and non-supportive interactions in families with a type 2 diabetes patient: an integrative review
Bennich, B. B., Røder, M. E., Overgaard, D., Egerod, Ingrid Eugenie, Munch, L., Knop, Filip Krag, Vilsbøll, Tina & Konradsen, H., 2017, In: Diabetology & Metabolic Syndrome. 9, 10 p., 57.Research output: Contribution to journal › Review › Research › peer-review
- Published
Metformin potentiates bile acid-induced GLP-1 secretion in patients with type 2 diabetes
Bronden, A., Alber, A., Rohde, U., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Diabetologia. 60, p. 113-113 242.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Clinical Pharmacokinetics and Pharmacodynamics of Albiglutide
Brønden, A., Knop, Filip Krag & Christensen, Mikkel Bring, 2017, In: Clinical Pharmacokinetics. 56, 7, p. 719-731Research output: Contribution to journal › Review › Research › peer-review
- Published
Single-Dose Metformin Enhances Bile Acid-Induced Glucagon-Like Peptide-1 Secretion in Patients With Type 2 Diabetes
Brønden, A., Albér, A., Rohde, U., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Nov 2017, In: The Journal of clinical endocrinology and metabolism. 102, 11, p. 4153-4162 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cardiovascular safety and benefits of GLP-1 receptor agonists
Dalsgaard, N. B., Brønden, A., Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Expert Opinion on Drug Safety. 16, 3, p. 351-363 13 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Effects of liraglutide on cardiovascular risk factors in patients with type 1 diabetes
Dejgaard, T. F., Johansen, N. B., Frandsen, C. S. S., Asmar, A., Tarnow, L., Knop, Filip Krag, Madsbad, Sten & Andersen, H. U., May 2017, In: Diabetes, Obesity and Metabolism. 19, 5, p. 734–738Research output: Contribution to journal › Letter › Research › peer-review
- Published
'No cognitive-enhancing effect of GLP-1 receptor agonism in antipsychotic-treated, obese patients with schizophrenia': authors' response
Ebdrup, Bjørn, Ishøy, P. L., Fagerlund, Birgitte, Broberg, B. V., Bak, N., Knop, Filip Krag & Glenthøj, Birte Yding, Nov 2017, In: Acta Psychiatrica Scandinavica. 136, 5, p. 526-527Research output: Contribution to journal › Comment/debate › Research
- Published
Incidence and Prognosis of Psoriasis and Psoriatic Arthritis in Patients Undergoing Bariatric Surgery
Egeberg, A., Sørensen, J. A., Gislason, Gunnar Hilmar, Knop, Filip Krag & Skov, Lone, 2017, In: J A M A Surgery. 152, 4, p. 344-349Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is double-blinding achievable in a placebo-controlled trial with the glucagon-like-peptide-1 receptor agonist liraglutide?
Foghsgaard, S., Vedtofte, L., Bahne, E., Andreasen, C., Christiansen, L. K., Svare, J. A., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Gluud, Lise Lotte, Knop, Filip Krag & Vilsbøll, Tina, 2017, In: Diabetologia. 60, S1, p. S369-S369Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Nonalcoholic Fatty Liver Disease Is Prevalent in Women With Prior Gestational Diabetes Mellitus and Independently Associated With Insulin Resistance and Waist Circumference
Foghsgaard, S., Andreasen, C., Vedtofte, L., Andersen, E. S., Bahne, E., Strandberg, C., Buhl, T., Holst, Jens Juul, Svare, J. A., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Gluud, Lise Lotte, Knop, Filip Krag & Vilsbøll, Tina, Jan 2017, In: Diabetes Care. 40, 1, p. 109-116 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Women with prior gestational diabetes mellitus and prediabetes are characterised by a decreased incretin effect
Foghsgaard, S., Vedtofte, L., Andreasen, C., Andersen, E. S., Bahne, E., Bagger, J. I., Svare, J. A., Holst, Jens Juul, Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Knop, Filip Krag & Vilsbøll, Tina, Jul 2017, In: Diabetologia. 60, 7, p. 1344-1353 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Current Therapies That Modify Glucagon Secretion: What Is the Therapeutic Effect of Such Modifications?
Grøndahl, M. F., Keating, D. J., Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Current Diabetes Reports. 17, 12, 10 p., 128.Research output: Contribution to journal › Review › Research › peer-review
- Published
Bile acid sequestrants for glycemic control in patients with type 2 diabetes: A systematic review with meta-analysis of randomized controlled trials
Hansen, M., Sonne, David Peick, Mikkelsen, K. H., Gluud, Lise Lotte, Vilsbøll, Tina & Knop, Filip Krag, May 2017, In: Journal of Diabetes and its Complications. 31, 5, p. 918-927 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon and Amino Acids Are Linked in a Mutual Feedback Cycle: The Liver-α-Cell Axis
Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens & Knop, Filip Krag, Feb 2017, In: Diabetes. 66, 2, p. 235-240 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Gut: A Key to the Pathogenesis of Type 2 Diabetes?
Holst, Jens Juul, Pedersen, Jens, Albrechtsen, Nicolai Jacob Wewer & Knop, Filip Krag, Aug 2017, In: Metabolic Syndrome and Related Disorders. 15, 6, p. 259-262 4 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
No cognitive-enhancing effect of GLP-1 receptor agonism in antipsychotic-treated, obese patients with schizophrenia
Ishøy, P. L., Fagerlund, Birgitte, Broberg, B. V., Bak, N., Knop, Filip Krag, Glenthøj, Birte Yding & Ebdrup, Bjørn, Jul 2017, In: Acta Psychiatrica Scandinavica. 136, 1, p. 52-62Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of GLP-1 Receptor Agonist Treatment on Body weight in Obese Antipsychotic-treated Patients with Schizophrenia: a Randomized, Placebo-controlled Trial Byline
Ishøy, P. L., Knop, Filip Krag, Broberg, B. V., Bak, N., Andersen, U. B., Jørgensen, N. R., Holst, Jens Juul, Glenthøj, Birte Yding & Ebdrup, Bjørn, Feb 2017, In: Diabetes, Obesity and Metabolism. 19, 2, p. 162-171Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of exercise combined with glucagon-like peptide-1 receptor agonist treatment on cardiac function: A randomized double-blind placebo-controlled clinical trial
Jørgensen, P. G., Jensen, M. T., Mensberg, P., Storgaard, H., Nyby, S., Jensen, J. S., Knop, Filip Krag & Vilsbøll, Tina, 2017, In: Diabetes, Obesity and Metabolism. 19, 7, p. 1040-1044Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exenatide: pharmacokinetics, clinical use, and future directions
Knop, Filip Krag, Bronden, A. & Vilsbøll, Tina, 2017, In: Expert Opinion on Pharmacotherapy. 18, 6, p. 555-571 17 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Improvement of Insulin Sensitivity after Lean Donor Feces in Metabolic Syndrome Is Driven by Baseline Intestinal Microbiota Composition
Kootte, R. S., Levin, E., Salojärvi, J., Smits, L. P., Hartstra, A. V., Udayappan, S. D., Hermes, G., Bouter, K. E., Koopen, A. M., Holst, J. J., Knop, F. K., Blaak, E. E., Zhao, J., Smidt, H., Harms, A. C., Hankemeijer, T., Bergman, J. J. G. H. M., Romijn, H. A., Schaap, F. G., Olde Damink, S. W. M. & 8 others, , Oct 2017, In: Cell Metabolism. 26, 4, p. 611-619.e6 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence connecting old, new and neglected glucose-lowering drugs to bile acid-induced GLP-1 secretion: a review
Kårhus, M. L., Brønden, A., Sonne, D. P., Vilsbøll, Tina & Knop, Filip Krag, Sep 2017, In: Diabetes, Obesity and Metabolism. 19, 9, p. 1214-1222Research output: Contribution to journal › Review › Research › peer-review
- Published
Julefrokostdilemmaet
Lanng, A. R., Gasbjerg, L. S. & Knop, Filip Krag, 11 Dec 2017, In: Ugeskrift for Laeger. 179, 25, p. 2212-15 4 p., V69590.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of empagliflozin on oxidative nucleic acid modifications in patients with type 2 diabetes: Protocol for a randomised, double-blinded, placebo-controlled trial
Larsen, E. L., Cejvanovic, V., Kjær, L. K., Vilsbøll, Tina, Knop, Filip Krag, Rungby, Jørgen & Poulsen, Henrik Enghusen, May 2017, In: BMJ Open. 7, 5, 6 p., e014728.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon elimination is increased in patients with type 2 diabetes
Lund, A. B., Grøndahl, M. F., Bagger, J. I., Holst, Jens Juul, Christensen, M., Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Diabetologia. 60, p. S240-S240Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Near-normalization of glycaemic control with glucagon-like peptide-1 receptor agonist treatment combined with exercise in patients with type 2 diabetes
Mensberg, P., Nyby, S., Jørgensen, P. G., Storgaard, H., Jensen, M. T., Sivertsen, J., Holst, Jens Juul, Kiens, Bente, Richter, Erik A., Knop, Filip Krag & Vilsbøll, Tina, 2017, In: Diabetes, Obesity and Metabolism. 19, 2, p. 172-180 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of antibiotics in childhood and risk of Type 1 diabetes: a population-based case-control study
Mikkelsen, K. H., Knop, Filip Krag, Vilsbøll, Tina, Frost, M., Hallas, J. & Pottegård, A., Feb 2017, In: Diabetic Medicine. 34, 2, p. 272–277Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastrisk aspirationsbehandling er et muligt alternativ til behandling af fedme
Møller Christensen, M., Jorsal, T., Naver, L. P. S., Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Ugeskrift for Laeger. 179, 32, 4 p., V03170198.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Weight loss for overweight and obese individuals with gout: a systematic review of longitudinal studies
Nielsen, S. M., Bartels, E. M., Henriksen, Marius, Wæhrens, E. E., Gudbergsen, Henrik Rindel, Bliddal, Henning, Astrup, A., Knop, Filip Krag, Carmona, L., Taylor, W. J., Singh, J. A., Perez-Ruiz, F., Kristensen, L. E. & Christensen, R., 2017, In: Annals of the Rheumatic Diseases. 76, 11, p. 1870-1882 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The impact of EndoBarrier gastrointestinal liner in obese patients with normal glucose tolerance and in patients with type 2 diabetes
Rohde, U., Federspiel, C. A., Vilmann, Peter, Langholz, Ebbe, Friis, S. U., Krakauer, M., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Feb 2017, In: Diabetes, Obesity and Metabolism. 19, 2, p. 189-199 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mathematical Modelling of Glucose-Dependent Insulinotropic Polypeptide and Glucagon-like Peptide-1 following Ingestion of Glucose
Røge, R. M., Bagger, J. I., Alskär, O., Kristensen, N. R., Klim, S., Holst, Jens Juul, Ingwersen, S. H., Karlsson, M. O., Knop, Filip Krag, Vilsbøll, Tina & Kjellsson, M. C., Oct 2017, In: Basic & Clinical Pharmacology & Toxicology. 121, 4, p. 290-297 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 40100368
Most downloads
-
439
downloads
L-cell Differentiation Is Induced by Bile Acids Through GPBAR1 and Paracrine GLP-1 and Serotonin Signaling
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
372
downloads
Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
304
downloads
Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production
Research output: Contribution to journal › Journal article › Research › peer-review
Published