Sten Madsbad

Sten Madsbad

Clinical Professor

Member of:

  • Internal Medicine: Endocrinology


  1. 2010
  2. Published

    Desaturation of excess intramyocellular triacylglycerol in obesity: implications for glycemic control

    Haugaard, S. B., Madsbad, Sten, Mu, H. & Vaag, A., 1 Mar 2010, In: International Journal of Obesity. 34, 3, p. 500-10 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Regional anatomic differences in skeletal muscle mitochondrial respiration in type 2 diabetes and obesity

    Rabøl, R., Larsen, Steen, Højberg, P. M. V., Almdal, Thomas Peter, Boushel, R. C., Haugaard, Steen Bendix, Andersen, J. L., Madsbad, Sten & Dela, Flemming, 1 Feb 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 2, p. 857-63 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Adding liraglutide to oral antidiabetic drug therapy: onset of treatment effects over time

    Gallwitz, B., Vaag, Allan, Falahati, A., Madsbad, Sten, Gallwitz, B., Vaag, A., Falahati, A. & Madsbad, Sten, 2010, In: International Journal of Clinical Practice. 64, 2, p. 267-76 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    At tro, at 50-60 årig ekan tabe sig, er naivt

    Madsbad, Sten, 2010, Diabetes inspiration til almen praksis. Dagens Medicin, p. 14-21 7 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  6. Published

    Desaturation of excess intramyocellular triacylglycerol in obesity: implications for glycemic control

    Haugaard, Steen Bendix, Madsbad, Sten, Mu, Huiling & Vaag, Allan, 2010, In: International Journal of Obesity. 34, 3, p. 500-510 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Effect of glucagon-like peptide-1 on alpha- and beta-cell function in C-peptide-negative type 1 diabetic patients

    Kielgast, U., Asmar, M., Madsbad, Sten & Holst, Jens Juul, 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 5, p. 2492-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Insulin resistance and glucose intolerance independently reduce the incretin effect via a beta cell defect

    Jensen, D. H., Aaboe, K., Voelund, A., Henriksen, J. E., Holst, J. M., Madsbad, Sten & Krarup, T., 2010, In: Diabetologia. 53

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  9. Published

    New physiological effects of incretin hormones GLP-1 and GIP

    Madsbad, Sten, 2010, Hvidovre Hospital. 56 p.

    Research output: Book/ReportPh.D. thesisResearch

  10. Published

    Non-insulin parenteral therapies

    Madsbad, Sten, 2010, Textbook of Diabetes. Fourth Edition ed. Oxford, Vol. Volume 1. p. 215-235 20 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  11. Published

    On the role of glucose-dependent insulintropic polypeptide in postprandial metabolism in humans

    Asmar, M., Tangaa, W., Madsbad, Sten, Hare, K., Astrup, A., Flint, A., Bülow, J. & Holst, Jens Juul, 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 298, 3, p. E614-21 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Opposite effects of pioglitazone and rosiglitazone on mitochondrial respiration in skeletal muscle of patients with type 2 diabetes

    Rabøl, R., Boushel, R., Almdal, Thomas Peter, Hansen, C. N., Ploug, Thorkil, Haugaard, Steen Bendix, Prats Gavalda, Clara, Madsbad, Sten & Dela, Flemming, 2010, In: Diabetes, Obesity and Metabolism Online. 12, 9, p. 806-814 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Pancreatic beta-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes

    Asmar, M., Højberg, P. V., Deacon, Carolyn F., Hare, K., Holst, Jens Juul & Madsbad, Sten, 2010, In: Regulatory Peptides. 160, 1-3, p. 175-80 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Pancreatic ß-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes

    Asmar, M., Højberg, P., Deacon, Carolyn F., Hare, K., Holst, Jens Juul & Madsbad, Sten, 2010, In: Regulatory Peptides. 160, 1-3, p. 175-180 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Postprandial diabetic glucose tolerance is normalized by gastric bypass feeding as opposed to gastric feeding and is associated with exaggerated GLP-1 secretion: a case report

    Dirksen, C., Hansen, D. L., Madsbad, Sten, Hvolris, L. E., Naver, L. S., Holst, Jens Juul & Worm, Dorte, 2010, In: Diabetes Care. 33, 2, p. 375-377

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Sustained low-dose growth hormone therapy optimizes bioactive insulin-like growth factor-I level and may enhance CD4 T-cell number in HIV infection

    Andersen, Ove, Hansen, B. R., Troensegaard, W., Flyvbjerg, A., Madsbad, Sten, Ørskov, H., Nielsen, J. O., Iversen, J. & Haugaard, S. B., 2010, In: Journal of Medical Virology. 82, 2, p. 197-205 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose- and non-glucose-induced insulin secretion in patients with type 2 diabetes mellitus

    Aaboe, K., Knop, Filip Krag, Vilsbøll, Tina, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2010, In: Diabetes, Obesity and Metabolism. 12, 4, p. 323-333 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. 2009
  19. Published

    Is Glycogen Synthase Kinase-3β an Ultraconserved Kernel Enzyme?

    Fenger, M., Haugaard, S. B., Andersen, Ove, Madsbad, Sten, Werge, T. & Linneberg, A., 11 Dec 2009, In: Gene Expression to Genetical Genomics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Incretin-based therapies: viewpoints on the way to consensus

    Nauck, M. A., Vilsbøll, Tina, Gallwitz, B., Garber, A. & Madsbad, Sten, 1 Nov 2009, In: Diabetes Care. 32 Suppl 2, p. S223-31

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Treatment of type 1 diabetic patients with glucagon-like peptide-1 (GLP-1) and GLP-1R agonists

    Kielgast, U., Holst, Jens Juul & Madsbad, Sten, Nov 2009, In: Current Diabetes Reviews. 5, 4, p. 266-75 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men

    Pilgaard, K., Jensen, C., Schou, J., Lyssenko, V., Wegner, L., Brøns, C., Vilsbøll, T., Hansen, T., Madsbad, S., Holst, J., Vølund, A., Poulsen, P., Groop, L., Pedersen, O., Vaag, A., Pilgaard, K., Jensen, C. B., Schou, J. H., Lyssenko, V., Wegner, L. & 10 others, Brøns, C., Vilsbøll, T., Hansen, T., Madsbad, Sten, Holst, J. M., Vølund, A., Poulsen, P., Groop, L., Pedersen, O. & Vaag, A., 1 Jul 2009, In: Diabetologia. 52, 7, p. 1298-307 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Tesofensine and weight loss - Authors' reply

    Astrup, A., Madsbad, Sten & Larsen, T. M., 26 Feb 2009, In: Lancet. 373, 9665, p. 720 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  24. Published

    Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene-gene interaction

    Sparsø, T., Grarup, N., Andreasen, C., Albrechtsen, A., Holmkvist, J., Andersen, G., Jørgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Madsbad, S., Hansen, T., Pedersen, O., Sparsø, T., Grarup, N., Andreasen, C., Albrechtsen, A., Holmkvist, J., Andersen, G., Jørgensen, T. & 6 others, Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Madsbad, Sten, Hansen, T. & Pedersen, O., 2009, In: Diabetologia. 52, 7, p. 1308-14 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Effect of Hyperglycemia on Mitochondrial Respiration in Type 2 Diabetes

    Rabøl, R., Højberg, P. M. V., Almdal, Thomas Peter, Boushel, R., Haugaard, S. B., Madsbad, Sten, Dela, Flemming, Rabøl, R., Højberg, P. M. V., Almdal, T., Boushel, R., Haugaard, S. B., Madsbad, Sten & Dela, F., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 4, p. 1372-78

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Effekt af tesofensine på kropsvægt og kropssammensætning hos svært overvægtige

    Nielsen, A. H., Larsen, T. M., Madsbad, Sten, Breum, Leif, Jensen, T. J., Kroustrup, J. P. & Astrup, A., 2009, In: Ugeskrift for læger. 171, 41-42, p. 2974-2977 4 p.

    Research output: Contribution to journalJournal articleResearch

  27. Published

    Exenatide and liraglutide: different approaches to develop GLP-1 receptor agonists (incretin mimetics)--preclinical and clinical results

    Madsbad, Sten, 2009, In: Best Practice & Research: Clinical Endocrinology & Metabolism. 23, 4, p. 463-77 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Expression of 11beta-hydroxysteroid dehydrogenase 1 and 2 in subcutaneous adipose tissue of lean and obese women with and without polycystic ovary syndrome

    Svendsen, P. F., Madsbad, Sten, Nilas, L., Paulsen, S. K., Pedersen, S. B., Svendsen, P. F., Madsbad, Sten, Nilas, L., Paulsen, S. K. & Pedersen, S. B., 2009, In: International Journal of Obesity. 33, 11, p. 1249-56 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans

    Sparsø, T., Bonnefond, A., Andersson, E., Bouatia-Naji, N., Holmkvist, J., Wegner, L., Grarup, N., Gjesing, A. P., Banasik, K., Cavalcanti-Proença, C., Marchand, M., Vaxillaire, M., Charpentier, G., Jarvelin, M-R., Tichet, J., Balkau, B., Marre, M., Lévy-Marchal, C., Faerch, K., Borch-Johnsen, K. & 36 others, Jørgensen, T., Madsbad, Sten, Poulsen, P., Vaag, Allan, Dina, C., Hansen, T., Pedersen, Oluf Borbye, Froguel, P., Sparsø, T., Bonnefond, A., Andersson, E., Bouatia-Naji, N., Holmkvist, J., Wegner, L., Grarup, N., Gjesing, A. P., Banasik, K., Cavalcanti-Proença, C., Marchand, M., Vaxillaire, M., Charpentier, G., Jarvelin, M., Tichet, J., Balkau, B., Marre, M., Lévy-Marchal, C., Faerch, K., Borch-Johnsen, K., Jørgensen, T., Madsbad, Sten, Poulsen, P., Vaag, A., Dina, C., Hansen, T., Pedersen, O. & Froguel, P., 2009, In: Diabetes. 58, 6, p. 1450-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Ghrelin receptor agonist (TZP-101) accelerates gastric emptying in adults with diabetes and symptomatic gastroparesis

    Ejskjaer, N., Vestergaard, E. T., Hellström, P. M., Gormsen, L. C., Madsbad, Sten, Madsen, J. L., Jensen, T. A., Pezzullo, J. C., Christiansen, J. S., Shaughnessy, L. & Kosutic, G., 2009, In: Alimentary Pharmacology and Therapeutics. 29, 11, p. 1179-87 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Improved glycaemic control decreases inner mitochondrial membrane leak in type 2 diabetes

    Rabøl, R., Højberg, P. M. V., Almdal, Thomas Peter, Boushel, R., Haugaard, S. B., Madsbad, Sten, Dela, Flemming, Rabøl, R., Højberg, P. M. V., Almdal, T., Boushel, R., Haugaard, S. B., Madsbad, Sten & Dela, F., 2009, In: Diabetic Medicine. 11, 4, p. 355-60 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Incretin hormone secretion in women with polycystic ovary syndrome: roles of obesity, insulin sensitivity, and treatment with metformin

    phk294, phk294, Nilas, L., Madsbad, Sten & Holst, Jens Juul, 2009, In: Metabolism - Clinical and Experimental. 58, 5, p. 586-593

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Intramyocellular triglyceride content in man, influence of sex, obesity and glycaemic control

    Haugaard, Steen Bendix, Madsbad, Sten, Mu, Huiling & Vaag, Allan, 2009, In: European Journal of Endocrinology. 161, 1, p. 57-64 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    K-ATP Channel Closure Ameliorates the Impaired Insulinotropic Effect of Glucose-Dependent Insulinotropic Polypeptide in Patients with Type 2 Diabetes

    Aaboe, K., Knop, K., Vilsboll, T., Volund, A., Simonsen, U., Deacon, C. F., Madsbad, Sten, Holst, J. J. & Krarup, T., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 2, p. 603-608 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide (GIP) in patients with type 2 diabetes

    Aaboe, K., Knop, Filip Krag, Vilsbøll, Tina, Vølund, A., Simonsen, U., Deacon, Carolyn F., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 2, p. 603-608

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Kirurgisk behandling af type 2-diabetes

    Olesen, S. C., Hansen, D. L., Almdal, Thomas Peter, Bendtsen, Flemming, Nordgaard, I., Hvolris, L. E., Holst, Jens Juul, Naver, L. & Madsbad, Sten, 2009, In: Ugeskrift for læger. 171, 8, p. 615-7 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Liraglutide (Victoza) - the first once-daily human GLP-1 receptor analogue

    Madsbad, Sten, 2009, In: Avances in Diabetologia. 25, p. 349-356 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Liraglutide effect and action in diabetes (LEAD).

    Madsbad, Sten, 2009, In: Expert Review of Endocrinology & Metabolism. 4, 2, p. 119-129 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Mitochondrial function in skeletal muscle in type 2 diabetes

    Madsbad, Sten, 2009

    Research output: Book/ReportPh.D. thesisResearch

  40. Published

    Preserved inhibitory potency of GLP-1 on glucagon secretion in type 2 diabetes mellitus

    Hare, K. J., Knop, Filip Krag, Asmar, M., Madsbad, Sten, Deacon, Carolyn F., Holst, Jens Juul & Vilsbøll, Tina, 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 12, p. 4679-87 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Reduced skeletal muscle mitochondrial respiration and improved glucose metabolism in nondiabetic obese women during a very low calorie dietary intervention leading to rapid weight loss

    Rabøl, R., Svendsen, P. F., Skovbro, M., Boushel, R., Haugaard, S. B., Schjerling, P., Schrauwen, P., Hesselink, M. K. C., Nilas, L., Madsbad, S., Dela, F., Rabøl, R., Svendsen, P. F., Skovbro, M., Boushel, R. C., Haugaard, S. B., Schjerling, P., Schrauwen, P., Hesselink, M. K. C., Nilas, L. & 2 others, Madsbad, Sten & Dela, F., 2009, In: Metabolism - Clinical and Experimental. 58, 8, p. 1145-52 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Remission af type 2-diabetes efter gastric bypass-kirurgi: et medicinsk mysterium?

    Jacobsen, S., Hansen, D. L., Worm, Dorte, Madsbad, Sten, Hvolris, L. E., Naver, L. P. S. & Holst, Jens Juul, 2009, In: Behandlerbladet. p. 20-29 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Skeletal muscle structural lipids improve during weight-maintenance after a very low calorie dietary intervention

    Haugaard, Steen Bendix, Vaag, Allan, Mu, Huiling & Madsbad, Sten, 2009, In: Lipids in Health and Disease. 8, p. 34 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Study rationale and design of the CIMT trial: the Copenhagen Insulin and Metformin Therapy trial

    Lundby Christensen, L., Almdal, T., Boesgaard, T., Breum, L., Dunn, E., Gade-Rasmussen, B., Gluud, C., Hedetoft, C., Jarloev, A., Jensen, T., Krarup, T., Johansen, L. B., Lund, S. S., Madsbad, S., Mathiesen, E., Moelvig, J., Nielsen, F., Perrild, H., Pedersen, O., Roeder, M. & 31 others, Snorgaard, O., Tarnow, L., Thorsteinsson, B., Vaag, Allan, drb459, drb459, Wetterslev, J., Wiinberg, N., CIMT Trial Group, C. T. G., Lundby Christensen, L., Almdal, T., Boesgaard, T., Breum, L., Dunn, E., Gade-Rasmussen, B., Gluud, C., Hedetoft, C., Jarloev, A., Jensen, T., Krarup, T., Johansen, L. B., Lund, S. S., Madsbad, Sten, Mathiesen, E., Moelvig, J., Nielsen, F., Perrild, Hans, Pedersen, O., Roeder, M., Snorgaard, O., Thorsteinsson, B. & drb459, drb459, 2009, In: Diabetes, Obesity and Metabolism. 11, 4, p. 315-22 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Tesofensine and weight loss: author's reply

    Astrup, A., Madsbad, Sten & Larsen, T. M., 2009, In: Lancet. 373, 9665, p. 720 1 p.

    Research output: Contribution to journalLetterResearchpeer-review

  46. Published

    The effect of tesofensine on weight loss: results from a one-armed, open-labelled extension study

    Astrup, A., Madsbad, Sten, Breum, Leif, Kroustrup, J. P., Raben, A., Jensen, J. K. S., Meier, D. & Sjödin, Anders Mikael, 2009, In: Obesity Facts. suppl. 2, p. 211-212 2 p.

    Research output: Contribution to journalConference abstract in journalResearch

  47. Published

    The insulin-resistant phenotype of polycystic ovary syndrome

    Svendsen, P. F., Madsbad, Sten & Nilas, L., 2009, In: Fertility and Sterility. 94, 3, p. 1052-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    The long-term effect of tesofensine on weight loss: interim results from a one-armed, open-labelled extension study

    Sjödin, Anders Mikael, Madsbad, Sten, Breum, Leif, Kroustrup, J. P., Raben, Anne, Jensen, J. K. S., Meier, D. & Astrup, A., 2009, In: Obesity. 17, Suppl. 2, p. S107 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  49. Published

    The prevalence of metabolic syndrome in Danish patients with HIV infection: the effect of antiretroviral therapy

    Hansen, B. R., Petersen, J., Haugaard, Steen Bendix, Madsbad, Sten, Obel, Niels, Suzuki, Y., Andersen, O., Hansen, B. R., Petersen, J., Haugaard, S. B., Madsbad, Sten, Obel, N., Suzuki, Y. & Andersen, Ove, 2009, In: HIV Medicine. 10, 6, p. 378-87 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Treatment of type 1 diabetic patients with glucagon-like peptide-1 (GLP-1) and GLP-1R agonists

    Kielgast, U., Holst, J., Madsbad, Sten, Kielgast, U., Holst, J. J. & Madsbad, Sten, 2009, In: Current Diabetes Reviews. 5, 4, p. 266-75 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Twelve weeks treatment with the DPP-4 inhibitor sitagliptin improves glycaemic control, but does not improve GLP-1 secretion, in patients with type 2 diabetes - a randomised trial

    Aaboe, K., Knop, F. K., Vilsbøll, Tina, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2009, In: Diabetologia. p. 748

    Research output: Contribution to journalConference abstract in journalResearch

  52. 2008
  53. Published

    Four weeks of near-normalization of blood glucose has no effect on postprandial GLP-1 and GIP secretion, but augments pancreatic B-cell responsiveness to a meal in patients with Type 2 diabetes

    Højberg, P. V., Vilsbøll, Tina, Zander, P. M., Knop, Filip Krag, Krarup, T., Vølund, A., Holst, J. M. & Madsbad, Sten, 1 Nov 2008, In: Diabetic Medicine. 25, 11, p. 1268-75 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Four weeks of near-normalization of blood glucose has no effect on postprandial GLP-1 and GIP secretion, but augments pancreatic B-cell responsiveness to a meal in patients with Type 2 diabetes

    Højberg, P. V., Vilsbøll, T., Zander, M., Knop, Filip Krag, Krarup, T., Vølund, A., Holst, Jens Juul & Madsbad, Sten, Nov 2008, In: Diabetic Medicine Online. 25, 11, p. 1268-75 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    GLP-1: physiological effects and potential therapeutic applications

    Aaboe, K., Krarup, T., Madsbad, Sten & Holst, Jens Juul, Nov 2008, In: Diabetes, Obesity and Metabolism Online. 10, 11, p. 994-1003 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Beneficial effects of once-daily liraglutide, a human glucagon-like peptide-1 analogue, on cardiovascular risk biomarkers in patients with Type 2 diabetes

    Courrèges, J., Vilsbøll, Tina, Zdravkovic, M., Le Thi Thanh, X., Krarup, T., Schmitz, O., Verhoeven, R., Bugáñová, I. & Madsbad, Sten, 1 Sep 2008, In: Diabetic Medicine. 25, 9, p. 1129-31 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Patient-reported rating of gastrointestinal adverse effects during treatment of type 2 diabetes with the once-daily human GLP-1 analogue, liraglutide

    Horowitz, M., Vilsbøll, Tina, Zdravkovic, M., Hammer, M. & Madsbad, Sten, 1 Jul 2008, In: Diabetes, Obesity and Metabolism. 10, 7, p. 593-6 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Glucagon-like peptide receptor agonists and dipeptidyl peptidase-4 inhibitors in the treatment of diabetes: a review of clinical trials

    Madsbad, Sten, Krarup, T., Deacon, Carolyn F. & Holst, Jens Juul, Jul 2008, In: Current Opinion in Clinical Nutrition and Metabolic Care. 11, 4, p. 491-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Nye biologiske laegemidler til behandling af kroniske inflammatoriske sygdomme

    Skov, Lone, Hegedüs, L., Madsbad, Sten & Bendtzen, K., 9 Jun 2008, In: Ugeskrift for Laeger. 170, 24, p. 2162

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Near normalisation of blood glucose improves the potentiating effect of GLP-1 on glucose-induced insulin secretion in patients with type 2 diabetes

    Højberg, P. V., Zander, M., Vilsbøll, T., Knop, Filip Krag, Krarup, T., Vølund, A., Holst, Jens Juul & Madsbad, Sten, 1 Apr 2008, In: Diabetologia. 51, 4, p. 632-640 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Liraglutide, a once-daily human GLP-1 analogue, improves pancreatic B-cell function and arginine-stimulated insulin secretion during hyperglycaemia in patients with Type 2 diabetes mellitus

    Vilsbøll, Tina, Brock, B., Perrild, H., Levin, K., Lervang, H., Kølendorf, K. E., Krarup, T., Schmitz, O., Zdravkovic, M., Le Thi Thanh, X. & Madsbad, Sten, 1 Feb 2008, In: Diabetic Medicine. 25, 2, p. 152-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Altered PI3-kinase/Akt signalling in skeletal muscle of young men with low birth weight

    Jensen, C. B., Martin-Gronert, M. S., Storgaard, H., Madsbad, Sten, Vaag, Allan, Ozanne, S. E., Jensen, C. B., Martin-Gronert, M. S., Storgaard, H., Madsbad, Sten, Vaag, A. & Ozanne, S. E., 2008, In: PLoS ONE. 3, 11, p. e3738

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Beneficial effects of once-daily liraglutide, ahuman glucagon-like peptide-1 analogue, on cardiovascular risk biomarkers in patientswith Type 2 diabetes

    Courreges, J., Vilsbøll, T., Zdravkovic, M., Le-Thi, T., Krarup, T., Schmitz, O., Verhoeven, R., Buganova, I. & Madsbad, Sten, 2008, In: Diabetic Medicine. 28, 9, p. 1129-1131

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    C-reactive protein, insulin resistance and risk of cardiovascular disease: a population-based study

    Hansen, T. W., Olsen, M. H., Rasmussen, S., Ibsen, H., Torp-Pedersen, Christian, Hildebrandt, P. R., Madsbad, Sten, Jeppesen, J., Hansen, T. W., Olsen, M. H., Rasmussen, S., Ibsen, H., Torp-Pedersen, C., Hildebrandt, P. R. & Madsbad, Sten, 2008, In: European Journal of Cardiovascular Prevention & Rehabilitation. 15, 5, p. 594-8 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Effect of tesofensine on bodyweight loss, body composition, and quality of life in obese patients: a randomised, double-blind, placebo-controlled trial

    Astrup, A., Madsbad, Sten, Breum, Leif, Jensen, T. J., Kroustrup, J. P. & Larsen, T. M., 2008, In: Lancet. 372, 9653, p. 1906-1913 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Effect of tesofensine on bodyweight loss, body composition, and quality of life in obese patients: a randomised, double-blind, placebo-controlled trial

    Astrup, A., Madsbad, Sten, Breum, L., Jensen, T. J., Kroustrup, J. P. & Larsen, T. M., 2008, In: Lancet. 372, 9653, p. 1906-13 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes

    Højberg, P. V., Vilsbøll, Tina, Rabøl, R., Knop, Filip Krag, Bache, M., Krarup, T., Holst, Jens Juul & Madsbad, Sten, 2008, In: Diabetologia. 52, 2, p. 199-207 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    GLP-1: physiological effects and potential therapeutic applications

    Aaboe, K., Krarup, T., Madsbad, Sten, Holst, Jens Juul, Aaboe, K., Krarup, T., Madsbad, Sten & Holst, J. J., 2008, In: Diabetic Medicine. 10, 11, p. 994-1003 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Ghrelin agonist (TZP-101) accelerates gastric emptying independently of the presence of autonomic neuropathy in patiens with diabetic gastroparesis

    Ejskjær, N., Hellström, P., Vestergaard, E. T., Madsbad, Sten, Madsen, J. L., Gormsen, L. C., Jensen, T. A., Pezzullo, J., Christensen, J. S., Shaughnessy, L. & Kotusic, G., 2008. 0 p.

    Research output: Contribution to conferencePaperResearchpeer-review

  70. Published

    Glucagon-like peptide receptor agonists and dipeptidyl peptidase-4 inhibitors in the treatment of diabetes: a review of clinical trials

    Madsbad, Sten, Krarup, T., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten, Krarup, T., Deacon, C. F. & Holst, J. J., 2008, In: Current Opinion in Clinical Nutrition and Metabolic Care. 11, 4, p. 491-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Glucagon-like peptide-1, glucose homeostasis and diabetes.

    Holst, Jens Juul, Deacon, Carolyn F., Vilsbøll, Tina, Krarup, T. & Madsbad, Sten, 2008, In: Trends in Molecular Medicine. 14, 4, p. 161-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Human amylin, pramlintide and GLP-1: Influence on gastric emptying, appetite and food intake in humans

    Asmar, M., Knop, F. K., Bache, M., Vilsboll, T., Madsbad, Sten & Holst, J. J., 2008, In: Diabetes. 57, Suppl. 1, p. A406-A407

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation

    Sparsø, T., Andersen, G., Albrechtsen, Anders, Jørgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Wasson, J., Permutt, M. A., Glaser, B., Madsbad, Sten, Pedersen, Oluf Borbye & Hansen, Torben, 2008, In: Diabetologia. 51, 9, p. 1646-52 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes

    Aaboe, K., Knop, Filip Krag, Vilsboll, T., Vølund, A., Simonsen, U., Deacon, Carolyn F., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2008, In: Journal of Clinical Endocrinology and Metabolism. 94, 2, p. 603-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Obesity, body composition and metabolic disturbances in polycystic ovary syndrome

    Svendsen, P. F., Nilas, L., Nørgaard, Kirsten, Jensen, Jens-Erik Beck & Madsbad, Sten, 2008, In: Human Reproduction. 23, 9, p. 2113-21 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Peripheral plasma C-peptide levels do not accuratly reflext prehepatic insulin secretion after intravenous glucose

    Kielgast, U., Højbjerg, P., Zander, M., Storgaard, H., Madsen, J. L., Møller, Søren, Vølund, A. & Madsbad, Sten, 2008. 0 p.

    Research output: Contribution to conferencePosterResearch

  77. Published

    Sex and muscle structural lipids in obese subjects - an impact on insulin action?

    Haugaard, S. B., Vaag, Allan, Høy, C. & Madsbad, Sten, 2008, In: European Journal of Clinical Investigation. 38, 7, p. 494-501 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    The proposed terminology 'A(1c)-derived average glucose' is inherently imprecise and should not be adopted. Reply to Bloomgarden ZT, Inzucchi SE, Karnieli E, et al. [letter]

    Haugaard, S. B., Madsbad, Sten & Mølvig, J., 2008, In: Diabetologia. 52, 3, p. 547-49

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Treatment of type 2 diabetes with incretin-based therapies

    Madsbad, Sten, 2008, In: Lancet. 373, 9662, p. 438-9

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. 2007
  81. Published

    Liraglutide, a long-acting human glucagon-like peptide-1 analog, given as monotherapy significantly improves glycemic control and lowers body weight without risk of hypoglycemia in patients with type 2 diabetes

    Vilsbøll, Tina, Zdravkovic, M., Le-Thi, T., Krarup, T., Schmitz, O., Courrèges, J., Verhoeven, R., Bugánová, I. & Madsbad, Sten, 1 Jun 2007, In: Diabetes Care. 30, 6, p. 1608-10 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Inappropriate suppression of glucagon during OGTT but not during isoglycaemic i.v. glucose infusion contributes to the reduced incretin effect in type 2 diabetes mellitus

    Knop, F. K., Vilsbøll, Tina, Madsbad, Sten, Holst, Jens Juul, Krarup, T., Knop, Filip Krag, Vilsbøll, Tina, Madsbad, Sten, Holst, J. M. & Krarup, T., 1 Apr 2007, In: Diabetologia. 50, 4, p. 797-805 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Inappropriate suppression of glucagon during OGTT but not during isoglycaemic i.v. glucose infusion contributes to the reduced incretin effect in type 2 diabetes mellitus

    Knop, Filip Krag, Vilsbøll, T., Madsbad, Sten, Holst, Jens Juul & Krarup, T., Apr 2007, In: Diabetologia. 50, 4, p. 797-805 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Altered skeletal muscle fiber composition and size precede whole-body insulin resistance in young men with low birth weight

    Jensen, C. B., Storgaard, H., Madsbad, Sten, Richter, Erik A. & Vaag, A. A., 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 4, p. 1530-1534 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Circulating sex hormones and gene expression of subcutaneous adipose tissue oestrogen and alpha-adrenergic receptors in HIV-lipodystrophy: implications for fat distribution.

    Andersen, Ove, Pedersen, S. B., Svenstrup, B., Hansen, B. R., Paulsen, S. K., Rathje, G. S., Richelsen, B., Nielsen, J. O., Madsbad, Sten, Iversen, J. & Haugaard, S. B., 2007, In: Clinical Endocrinology. 67, 2, p. 250-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Desaturation of skeletal muscle structural and depot lipids in obese individuals during a very-low-calorie diet intervention.

    Haugaard, S. B., Vaag, A., Høy, C. & Madsbad, Sten, 2007, In: Obesity. 15, 1, p. 117-25 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Glucose production, oxidation and disposal correlate with plasma lactate levels in HIV-infected patients on HAART

    Haugaard, S. B., Andersen, Ove, Madsbad, Sten, Iversen, J. S. & Dela, Flemming, 2007, In: Journal of Infection. 54, 1, p. 89-97 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Impaired proinsulin secretion before and during oral glucose stimulation in HIV-infected patients who display fat redistribution.

    Haugaard, S. B., Andersen, Ove, Halsall, I., Iversen, J., Hales, C. N. & Madsbad, Sten, 2007, In: Metabolism. 56, 7, p. 939-46 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Insulin resistance, the metabolic syndrome, and risk of incident cardiovascular disease: a population-based study.

    Jeppesen, J., Hansen, T. W., Rasmussen, S., Ibsen, H., Torp-Pedersen, C. & Madsbad, Sten, 2007, In: Journal of the American College of Cardiology. 49, 21, p. 2112-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Reduced incretin effect in type 2 diabetes: cause or consequence of the diabetic state?

    Knop, F. K., Vilsbøll, Tina, Højberg, P. V., Larsen, S., Madsbad, Sten, Vølund, A., Holst, Jens Juul & Krarup, T., 2007, In: Diabetes. 56, 8, p. 1951-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7,088 Danish whites

    Sparsø, T., Hussain, M. S., Borch-Johnsen, K., Jørgensen, T., Madsbad, Sten, Hansen, Torben, Pedersen, Oluf Borbye & Andersen, G., 2007, In: Molecular Genetics and Metabolism. 92, 3, p. 278-282 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes

    Sparsø, T., Andersen, G., Nielsen, T., Burgdorf, K. S., Gjesing, A. M. P., Nielsen, A. L., Albrechtsen, Anders, Rasmussen, S. S., Jørgensen, T., Borch-Johnsen, K., Sandbaek, A., Lauritzen, T., Madsbad, Sten, Hansen, Torben & Pedersen, Oluf Borbye, 2007, In: Diabetologia. 51, 1, p. 70-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    The insulinotropic effect of GIP is impaired in patients with chronic pancreatitis and secondary diabetes mellitus as compared to patients with chronic pancreatitis and normal glucose tolerance.

    Knop, F. K., Vilsbøll, Tina, Højberg, P. V., Larsen, S., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2007, In: Regulatory Peptides. 144, 1-3, p. 123-30 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. 2006
  95. Published

    Plasma dipeptidyl peptidase-IV activity in patients with type-2 diabetes mellitus correlates positively with HbAlc levels, but is not acutely affected by food intake

    Ryskjaer, J., Deacon, Carolyn F., Carr, R. D., Krarup, T., Madsbad, Sten, Holst, Jens Juul, Vilsbøll, Tina, Ryskjaer, J., Deacon, C. F., Carr, R. D., Krarup, T., Madsbad, Sten, Holst, J. J. & Vilsbøll, T., 1 Sep 2006, In: European Journal of Endocrinology. 155, 3, p. 485-93 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    IRS-1 serine phosphorylation and insulin resistance in skeletal muscle from pancreas transplant recipients

    Bouzakri, K., Karlsson, H. K. R., drb459, drb459, Madsbad, Sten, Christiansen, E. & Zierath, Juleen R, Mar 2006, In: Diabetes. 55, 3, p. 785-91 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    The metabolite generated by dipeptidyl-peptidase 4 metabolism of glucagon-like peptide-1 has no influence on plasma glucose levels in patients with type 2 diabetes

    Zander, M., Madsbad, Sten, Deacon, Carolyn F. & Holst, Jens Juul, Feb 2006, In: Diabetologia. 49, 2, p. 369-74 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    A low-fat Diet improves insulin sensitivity in patients with type 1 diabetes

    Rosenfalck, A., Almdal, T. P., Viggers, L., Madsbad, Sten & Hilsted, J., 2006, In: Diabetic Medicine. 23, p. 384-392 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Betydning af fysisk aktivitet og fitness for fedmens komplikationer

    Berentzen, T., Madsbad, Sten, Sørensen, Thorkild I.A. & Astrup, A., 2006, In: Ugeskrift for læger. 168, 2, p. 144-149 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Dietary intervention increases n-3 long-chain polyunsaturated fatty acids in sceletal muscle membrane phospholipids of obese subjects. Inplications for insulin sensitivity

    Haugaard, S. B., Madsbad, Sten, Høy, C. & Vaag, A., 2006, In: Clinical Endocrinology. 64, p. 169-178 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Effect of orlistat on weight regain and cardiovascular risk factors following a very-low-energy diet in abdominally obese patients: a 3-year randomized, placebo-controlled study.

    Richelsen, B., Tonstad, S., Rössner, S., Toubro, S., Niskanen, L., Madsbad, Sten, Mustajoki, P. & Rissanen, A., 2006, In: Diabetes Care. 30, 1, p. 27-32 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. Published

    Glucose-stimulated prehepatic insulin secretion is associated with circulating alanine, triglyceride, glucagons, lactate and TNF-alfa in patients with HIV-lipodystrophy

    Haugaard, S. B., Andersen, Ove, Pedersen, S., Dela, Flemming, Holst, Jens Juul, Deacon, Carolyn F., Iversen, J. & Madsbad, Sten, 2006, In: HIV Medicine. 7, p. 163-172 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. Published

    Growth factors, glucose and insulin kinetics after low dose growth hormone in HIV - lipodystrophy

    Haugaard, S. B., Andersen, Ove, Flyvbjerg, A., Ørskov, H., Madsbad, Sten & Iversen, J., 2006, In: Journal of Infection. 52, 6, p. 389-398 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  104. Published

    Hyperproinsulinaemia in normoglycaemic lipodystrophic HIV-infected patients

    Haugaard, S. B., Andersen, Ove, Hales, C., Halsall, I., Rosenfalck, A., Iversen, J. & Madsbad, Sten, 2006, In: European Journal of Clinical Investigation. 36, p. 436-445 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  105. Published

    IRS-1 serine phosphorylation and insulin resistance in skeletal muscle from pancreas tranplant recipient

    Bouzakri, K., Karlsson, H., Vestergaard, H., Madsbad, Sten, Christiansen, E. & Zierath, J., 2006, In: Diabetes. 55, p. 785-91 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 10877