Filip Krag Knop

Filip Krag Knop

Clinical Professor

Member of:

  • Internal Medicine: Endocrinology


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  1. Published

    Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose and non-glucose induced insulin secretion in patients with type 2 diabetes mellitus

    Aaboe, K., Knop, Filip Krag, Vilsbøll, T., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, S. & Krarup, T. M., 1 Apr 2010, In: Diabetes, Obesity and Metabolism. 12, 4, p. 323-33 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose- and non-glucose-induced insulin secretion in patients with type 2 diabetes mellitus

    Aaboe, K., Knop, Filip Krag, Vilsbøll, Tina, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2010, In: Diabetes, Obesity and Metabolism. 12, 4, p. 323-333 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide (GIP) in patients with type 2 diabetes

    Aaboe, K., Knop, Filip Krag, Vilsbøll, Tina, Vølund, A., Simonsen, U., Deacon, Carolyn F., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 2, p. 603-608

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes

    Aaboe, K., Knop, Filip Krag, Vilsboll, T., Vølund, A., Simonsen, U., Deacon, Carolyn F., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2008, In: Journal of Clinical Endocrinology and Metabolism. 94, 2, p. 603-8 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Hepatic Fibrosis Evaluated in Patients with Type 2 Diabetes with and without Chronic Kidney Disease

    Adrian, T., Hornum, Mads, Knop, Filip Krag, Christensen, Karl Bang, Almdal, Thomas Peter, Rossing, Peter, Lídaa, L. Í., Heinrich, N. S., Boer, V. O., Marsman, A., Petersen, E. T., Siebner, Hartwig Roman & Feldt-Rasmussen, Bo, 2023, In: Nephron. 147, 11, p. 673–684 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Prevalence of non-alcoholic fatty liver disease in patients with chronic kidney disease: a cross-sectional study

    Adrian, T., Sørensen, I. M. H., Knop, Filip Krag, Bro, S., Ballegaard, E. L. F., Nordestgaard, Børge, Fuchs, A., Kofoed, Klaus Fuglsang, Kühl, J. T., Sigvardsen, P. E., Hornum, Mads & Feldt-Rasmussen, Bo, 2022, In: Nephrology Dialysis Transplantation. 37, 10, p. 1927-1934 gfab266.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Nonalcoholic Fatty Liver Disease in Patients with Type 2 Diabetes and Chronic Kidney Disease

    Adrian, T., Hornum, Mads, Knop, Filip Krag, Almdal, Thomas Peter, Rossing, Peter, Lida, L., Heinrich, N. S., Boer, V. O., Marsman, A., Petersen, E. T., Siebner, Hartwig Roman & Feldt-Rasmussen, Bo, 2023, In: Nephron. 147, 6, p. 317–328

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Incidental finding of non-alcoholic steatohepatitis-cirrhosis

    Adrian, T., Hornum, Mads, Knop, Filip Krag & Gluud, Lise Lotte, 2022, In: Endocrinology, Diabetes and Metabolism Case Reports. 2022, 1, 5 p., 22-0350.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production

    Albrechtsen, N. J. W., Kuhre, R. E., Hornburg, D., Jensen, C. Z., Hornum, M., Dirksen, C., Svane, M., Gasbjerg, L. S., Jorgensen, N. B., Gabe, M. N., Balk-Moller, E., Albrechtsen, R., Winther-Sorensen, M., Galsgaard, K. D., Meissner, F., Jorsal, T., Lund, A., Vilsboll, T., Eliasen, R., Bojsen-Moller, K. N. & 9 others, Idorn, T., Deacon, Carolyn F., Knop, Filip Krag, Rosenkilde, Mette, Hartmann, Bolette, Feldt-Rasmussen, Bo, Mann, Matthias, Madsbad, Sten & Holst, Jens Juul, Nov 2017, In: Cell Reports. 21, 6, p. 1452-1460

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Hyperglucagonaemia analysed by glucagon sandwich ELISA: nonspecific interference or truly elevated levels?

    Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Veedfald, Simon, Windeløv, Johanne Agerlin, Plamboeck, A., Bojsen-Møller, K. N., Idorn, T., Feldt-Rasmussen, Bo, Knop, Filip Krag, Vilsbøll, T., Madsbad, Sten, Deacon, Carolyn F. & Holst, Jens Juul, 3 Jun 2014, In: Diabetologia. 57, 9, p. 1919-1926 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Short-acting glucagon-like peptide-1 receptor agonists as add-on to insulin therapy in type 1 diabetes: A review

    Albèr, A., Brønden, A. & Knop, Filip Krag, 2017, In: Diabetes, Obesity and Metabolism. 19, 7, p. 915-925

    Research output: Contribution to journal › Review › Research › peer-review

  12. Published

    Semimechanistic model describing gastric emptying and glucose absorption in healthy subjects and patients with type 2 diabetes

    Alskär, O., Bagger, J. I., Røge, R. M., Knop, Filip Krag, Karlsson, M. O., Vilsbøll, Tina & Kjellsson, M. C., Mar 2016, In: Journal of Clinical Pharmacology. 56, 3, p. 340-348 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    The impact of acute glycaemic fluctuations on left ventricular systolic function in insulin-treated type 2 diabetes

    Andersen, A., Jorgensen, P. G., Bagger, J. I., Baldassarre, M. P. A., Christensen, M., Abelin, K. U., Faber, Jens, Pedersen-Bjergaard, Ulrik, Holst, Jens Juul, Lindhardt, T., Gislason, Gunnar Hilmar, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Diabetologia. 63, SUPPL 1, p. S429-S429 897.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  14. Published

    Associations of hypoglycaemia and glycaemic variability with cardiac arrhythmias using a long-term monitoring approach in insulin-treated patients with type 2 diabetes

    Andersen, A., Bagger, J. I., Sorensen, S. K., Baldassarre, M. P. A., Pedersen-Bjergaard, Ulrik, Forman, Julie Lyng, Gislason, Gunnar Hilmar, Lindhardt, T. B., Knop, Filip Krag & Vilsbøll, Tina, 2021, In: Diabetologia. 64, SUPPL 1, p. 135-135 257.

    Research output: Contribution to journal › Conference abstract in journal › Research

  15. Published

    A Pharmacological and Clinical Overview of Oral Semaglutide for the Treatment of Type 2 Diabetes

    Andersen, A., Knop, Filip Krag & Vilsbøll, Tina, 2021, In: Drugs. 81, p. 1003-1030 28 p.

    Research output: Contribution to journal › Review › Research › peer-review

  16. Published

    Glucagon-like peptide 1 in health and disease

    Andersen, A., Lund, A., Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Nature Reviews Endocrinology. 14, p. 390-403

    Research output: Contribution to journal › Review › Research › peer-review

  17. Published

    Hypoglycaemia and cardiac arrhythmias in diabetes

    Andersen, A., Jørgensen, P. G., Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Therapeutic Advances in Endocrinology and Metabolism. 11, 11 p., 2042018820911803.

    Research output: Contribution to journal › Review › Research › peer-review

  18. Published

    Associations of hypoglycemia, glycemic variability and risk of cardiac arrhythmias in insulin-treated patients with type 2 diabetes: a prospective, observational study

    Andersen, A., Bagger, J. I., Sørensen, S. K., Baldassarre, M. P. A., Pedersen-Bjergaard, Ulrik, Forman, Julie Lyng, Gislason, Gunnar Hilmar, Lindhardt, T. B., Knop, Filip Krag & Vilsbøll, Tina, 2021, In: Cardiovascular Diabetology. 20, 1, 10 p., 241.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Acute hypoglycemia and risk of cardiac arrhythmias in insulin-treated type 2 diabetes and controls

    Andersen, A., Bagger, J. I., Baldassarre, M. P., Christensen, Mikkel Bring, Abelin, K. U., Faber, Jens, Pedersen-Bjerregaard, U., Holst, Jens Juul, Lindhardt, T. B., Gislason, Gunnar Hilmar, Knop, Filip Krag & Vilsbøll, Tina, 2021, In: European Journal of Endocrinology. 185, 2, p. 343-353 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Acute changes in plasma glucose increases left ventricular systolic function in insulin-treated patients with type 2 diabetes and controls

    Andersen, A., Jørgensen, P. G., Bagger, J., Baldassarre, M. P. A., Christensen, Mikkel Bring, Pedersen-Bjergaard, Ulrik, Lindhardt, T. B., Gislason, Gunnar Hilmar, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: Diabetes, Obesity and Metabolism. 24, 6, p. 1123-1131

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Glukagonlignende peptid 1-receptoragonister til behandling af type 2-diabetes

    Andersen, A., Christensen, A. S., Knop, Filip Krag & Vilsbøll, Tina, 2022, In: Ugeskrift for Laeger. 181, 2, V10180725.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Empagliflozin to elderly and obese patients with increased risk of developing heart failure: Study protocol for the Empire Prevent trial program

    Andersen, Camilla, Larsen, J. H., Jensen, J., Omar, M., Nouhravesh, N., Kistorp, Caroline Michaela Nervil, Tuxen, C., Gustafsson, Finn, Knop, Filip Krag, Forman, Julie Lyng, Davidovski, Filip Søskov, Jensen, Lars Thorbjørn, Højlund, K., Køber, Lars Valeur, Antonsen, L., Poulsen, M. K., Schou, Morten & Møller, J. E., 2024, In: American Heart Journal. 271, p. 84-96 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Is glucagon‐like peptide‐1 fully protected by the dipeptidyl peptidase 4 inhibitor sitagliptin when administered to patients with type 2 diabetes?

    Andersen, E. S., Lund, A., Bagger, J. I., Andreasen, C., Grøndahl, M., Deacon, Carolyn F., Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, Aug 2018, In: Diabetes, Obesity and Metabolism. 20, 8, p. 1937-1943

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    MECHANISMS IN ENDOCRINOLOGY: The physiology of neuronostatin

    Andersen, M. R., Suppli, M. P., Bagger, J. I., Christensen, Mikkel Bring, Yosten, G. L. C., Knop, Filip Krag & Lund, A., 2021, In: European Journal of Endocrinology. 185, 4, p. R93-R101

    Research output: Contribution to journal › Review › Research › peer-review

  25. Published

    Adult atopic dermatitis and the risk of type 2 diabetes

    Andersen, Y. M. F., Egeberg, A., Gislason, Gunnar Hilmar, Skov, Lone, Knop, Filip Krag & Thyssen, Jacob Pontoppidan, Mar 2017, In: The Journal of allergy and clinical immunology. 139, 3, p. 1057-1059 3 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  26. Published

    Association between topical corticosteroid use and type 2 diabetes in two European population-based adult cohorts

    Andersen, Y. M. F., Egeberg, A., Ban, L., Gran, S., Williams, H. C., Francis, N. A., Knop, Filip Krag, Gislason, Gunnar Hilmar, Skov, Lone & Thyssen, Jacob Pontoppidan, 2019, In: Diabetes Care. 42, 6, p. 1095-1103

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    The impact of acute fluctuations in plasma glucose on echocardiographic derived measures of systolic function in patients with type 1 diabetes

    Andreasen, C. R., Andersen, A., Haqelqvist, P. G., Abelin, K., Lauritsen, J. V., Jorgensen, P. G., Engberg, S., Faber, Jens, Holst, Jens Juul, Pedersen-Bjergaard, Ulrik, Knop, Filip Krag & Vilsbøll, Tina, 2021, In: Diabetologia. 64, SUPPL 1, p. 135-136 2 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  28. Published

    Hypoglycaemia and rebound hyperglycaemia increase left ventricular systolic function in patients with type 1 diabetes

    Andreasen, C. R., Andersen, A., Hagelqvist, P. G., Lauritsen, J. V., Jørgensen, P. G., Engberg, S., Faber, Jens, Hartmann, Bolette, Pedersen-Bjergaard, Ulrik, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: Diabetes, Obesity and Metabolism. 24, 10, p. 2027-2037

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Sustained heart rate-corrected QT prolongation during recovery from hypoglycaemia in people with type 1 diabetes, independently of recovery to hyperglycaemia or euglycaemia

    Andreasen, C. R., Andersen, A., Hagelqvist, P. G., Maytham, K., Lauritsen, J. V., Engberg, S., Faber, Jens, Pedersen-Bjergaard, Ulrik, Knop, Filip Krag & Vilsbøll, Tina, 2023, In: Diabetes, Obesity and Metabolism. 25, 6, p. 1566-1575 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Understanding the place for GLP-1RA therapy: Translating guidelines for treatment of type 2 diabetes into everyday clinical practice and patient selection

    Andreasen, C. R., Andersen, A., Knop, Filip Krag & Vilsbøll, Tina, 2021, In: Diabetes, Obesity and Metabolism. 23, S3, p. 40-52 13 p.

    Research output: Contribution to journal › Review › Research › peer-review

  31. Published

    How glucagon-like peptide 1 receptor agonists work

    Andreasen, C. R., Andersen, A., Knop, Filip Krag & Vilsbøll, Tina, 2021, In: Endocrine Connections. 10, 7, p. R200-R212 13 p.

    Research output: Contribution to journal › Review › Research › peer-review

  32. Published

    Efficacy and safety of once-daily oral semaglutide 25 mg and 50 mg compared with 14 mg in adults with type 2 diabetes (PIONEER PLUS): a multicentre, randomised, phase 3b trial

    Aroda, V. R., Aberle, J., Bardtrum, L., Christiansen, E., Knop, Filip Krag, Gabery, S., Pedersen, S. D. & Buse, J. B., 2023, In: The Lancet. 402, 10403, p. 693-704 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Do the actions of glucagon-like peptide-1 on gastric emptying, appetite, and food intake involve release of amylin in humans?

    Asmar, M., Bache, M., Knop, Filip Krag, Madsbad, Sten & Holst, Jens Juul, 1 May 2010, In: The Journal of clinical endocrinology and metabolism. 95, 5, p. 2367-75 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Gut-derived glucagon in man: [Meeting Abstract]

    Baekdal, M., Lund, A., Albrechtsen, Nicolai Jacob Wewer, Egholk, J., Jorsal, T., Black-Juel, C. T., Dal, Jenna Elizabeth Hunt, Galsgaard, Katrine Douglas, Rigbolt, K., Palnaes, C., Ørskov, Cathrine, Poulsen, Steen Seier, Holst, Jens Juul, Villsboll, T. & Knop, Filip Krag, 2019, In: Diabetologia. 62, Supl. 1/SI, p. S231-S231 472.

    Research output: Contribution to journal › Conference abstract in journal › Research

  35. Published

    Counterregulatory responses to hypoglycaemia in totally pancreatectomised patients

    Baekdal, M., Lund, A., Baldassare, M. P. A., Rose, K., Egholk, J., Christensen, M. B., Hansen, C. P., Storkholm, J. H., Faber, Jens, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2020, In: Diabetologia. 63, SUPPL 1, p. S95-S95

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  36. Published

    Empagliflozin Normalizes Fasting Hyperglycemia and Improves Postprandial Glucose Tolerance in Totally Pancreatectomized Patients: A Randomized, Double-Blind, Placebo-Controlled Crossover Study

    Baekdal, M., Nielsen, S. W., Hansen, C. P., Storkholm, J. H., van Hall, Gerrit, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina, Lund, A. & Knop, Filip Krag, 2024, In: Diabetes Care. 47, 1, p. 71-80 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Glucagon antagonism as a potential therapeutic target in type 2 diabetes

    Bagger, J. I., Knop, Filip Krag, Holst, Jens Juul & Vilsbøll, Tina, Nov 2011, In: Diabetes, Obesity and Metabolism. 13, 11, p. 965-971 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Preserved postprandial GLP-1 and GIP responses in patients with maturity onset diabetes of the young

    Bagger, J. I., Ostoft, S. H., Hansen, T., Pedersen, O., Holst, Jens Juul, Knop, Filip Krag & Vilsboll, T., 2013, In: Diabetologia. 56, p. S152-S152

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Increased liver fat content in totally pancreatectomised patients

    Bagger, J. I., Lund, A. B., Albrechtsen, Nicolai Jacob Wewer, Christensen, M., Grøndahl, M. F., Hansen, C. P., Storkholm, J., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Diabetologia. 60, S1, p. S572-S573

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  40. Published

    Diverse hepatic microbial DNA fingerprints in healthy lean and obese steatotic humans

    Bagger, J. I., Suppli, M. P., Nielsen, T., Lelouvier, B., Broha, A., Demant, M., Konig, M. J., Strandberg, C., Lund, A., Vilsbøll, Tina & Knop, Filip Krag, 2018, In: Diabetologia. 61, p. S120-S121

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  41. Published

    Impaired regulation of the incretin effect in patients with type 2 diabetes

    Bagger, J. I., Knop, Filip Krag, Lund, Asger Bach, drb459, drb459, Holst, Jens Juul & Vilsbøll, Tina, 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 3, p. 737-45 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Effect of Oxyntomodulin, Glucagon, GLP-1 and Combined Glucagon +GLP-1 Infusion on Food Intake, Appetite and Resting Energy Expenditure

    Bagger, J. I., Holst, Jens Juul, Hartmann, Bolette, Andersen, B., Knop, Filip Krag & Vilsbøll, T., 2015, In: The Journal of Clinical Endocrinology & Metabolism. 100, 12, p. 4541–4552 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Glucagon responses to increasing oral loads of glucose and corresponding isoglycaemic intravenous glucose infusions in patients with type 2 diabetes and healthy individuals

    Bagger, J. I., Knop, Filip Krag, Lund, Asger Bach, Holst, Jens Juul & Vilsbøll, T., 31 May 2014, In: Diabetologia. 57, 8, p. 1270-25 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Therapy for obesity based on gastrointestinal hormones

    Bagger, J. I., Christensen, M., Knop, Filip Krag & Vilsbøll, Tina, 2011, In: Review of Diabetic Studies. 8, 3, p. 339-47 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Glucagonostatic Potency of GLP-1 in Patients with Type 2 Diabetes, in Patients with Type 1 Diabetes, and Healthy Control Subjects

    Bagger, J. I., Grøndahl, M., Lund, Asger Bach, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2021, In: Diabetes. 70, 4, p. 1347-1356

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Involvement of glucagon-like peptide-1 in the glucose-lowering effect of metformin

    Bahne, E., Hansen, M., Brønden, A., Sonne, David Peick, Vilsbøll, Tina & Knop, Filip Krag, Oct 2016, In: Diabetes, Obesity and Metabolism Online. 18, 10, p. 955-61 7 p.

    Research output: Contribution to journal › Review › Research › peer-review

  47. Published

    Metformin-induced glucagon-like peptide-1 secretion contributes to the actions of metformin in type 2 diabetes

    Bahne, E., Sun, E. W. L., Young, R. L., Hansen, M., Sonne, D. P., Hansen, J. S., Rohde, U., Liou, A. P., Jackson, M. L., de Fontgalland, D., Rabbitt, P., Hollington, P., Sposato, L., Due, S., Wattchow, D. A., Rehfeld, Jens Frederik, Holst, Jens Juul, Keating, D. J., Vilsbøll, Tina & Knop, Filip Krag, 2018, In: JCI Insight. 3, 23, p. 1-16 e93936.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Metformin er en mulig glukagonlignende peptid-1-stimulator

    Bahne, E., Brønden, A., Vilsbøll, Tina & Knop, Filip Krag, 2018, In: Ugeskrift for Laeger. 180, 12, 4 p., V07170516.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Specificity and sensitivity of commercially available assays for glucagon-like peptide-1 (GLP-1): Implications for GLP-1 measurements in clinical studies

    Bak, M. J., Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Knop, Filip Krag, Vilsbøll, Tina, Jørgensen, N. B., Hartmann, Bolette, Deacon, Carolyn F., Dragsted, Lars Ove & Holst, Jens Juul, 2014, In: Diabetes, Obesity and Metabolism. 16, 11, p. 1155-1164 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Cardiovascular biomarkers in clinical studies of type 2 diabetes

    Baldassarre, M. P. A., Andersen, A., Consoli, A., Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Diabetes, Obesity and Metabolism. 20, 6, p. 1350-1360

    Research output: Contribution to journal › Review › Research › peer-review

  51. Published

    Call for prospective studies of continuous glucose monitoring to define the glycaemic response to bariatric surgery

    Bally, L., Khoo, B., Knop, Filip Krag, Madsbad, Sten, Patti, M. & Tan, T., 2023, In: The Lancet Diabetes and Endocrinology. 11, 10, p. 712-714 3 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  52. Published

    Patient Assessment of Family Function, Glycemic Control and Quality of Life in Adult Patients With Type 2 Diabetes and Incipient Complications

    Bennich, B. B., Munch, L., Egerod, Ingrid Eugenie, Konradsen, H., Ladelund, S., Knop, Filip Krag, Vilsbøll, Tina, Røder, M. & Overgaard, D., 2019, In: Canadian Journal of Diabetes. 43, 3, p. 193-200

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Supportive and non-supportive interactions in families with a type 2 diabetes patient: an integrative review

    Bennich, B. B., Røder, M. E., Overgaard, D., Egerod, Ingrid Eugenie, Munch, L., Knop, Filip Krag, Vilsbøll, Tina & Konradsen, H., 2017, In: Diabetology & Metabolic Syndrome. 9, 10 p., 57.

    Research output: Contribution to journal › Review › Research › peer-review

  54. Published

    Experience of family function, family involvement, and self-management in adult patients with type 2 diabetes: A thematic analysis

    Bennich, B. B., Munch, L., Overgaard, D., Konradsen, Hanne, Knop, Filip Krag, Roder, M., Vilsbøll, Tina & Egerod, Ingrid Eugenie, 2020, In: Journal of Advanced Nursing. 76, 2, p. 621-631

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Exogenous secretin decreases ad libitum food intake and exhibits a biphasic effect on supraclavicular brown adipose tissue activity in healthy men

    Bentzen, M. J., Heimburger, S. M. N., Hartmann, Bolette, Holst, Jens Juul, Christensen, Mikkel Bring & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 211-211 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  56. Published

    Mono- and co-activation of the GIP and GLP-1 receptors inhibits bone resorption

    Bergmann, N. C., Lund, A., Heimburger, S. M., Gasbjerg, Lærke Smidt, Jørgensen, Niklas Rye, Jessen, L., Hartmann, Bolette, Holst, Jens Juul, Christensen, Mikkel Bring, Vilsbøll, Tina & Knop, Filip Krag, 2018, In: Diabetologia. 61, S.1, p. S348-S348 717.

    Research output: Contribution to journal › Conference abstract in journal › Research

  57. Published

    Effects of combined GIP and GLP-1 infusion on energy intake, appetite and energy expenditure in overweight/obese individuals: a randomised, crossover study

    Bergmann, N. C., Lund, A., Gasbjerg, Lærke Smidt, Meessen, E. C. E., Andersen, M. M., Bergmann, S., Hartmann, Bolette, Holst, Jens Juul, Jessen, L., Christensen, Mikkel Bring, Vilsbøll, Tina & Knop, Filip Krag, 2019, In: Diabetologia. 62, 4, p. 665-675 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    No Acute Effects of Exogenous Glucose-Dependent Insulinotropic Polypeptide on Energy Intake, Appetite, or Energy Expenditure When Added to Treatment With a Long-Acting Glucagon-Like Peptide 1 Receptor Agonist in Men With Type 2 Diabetes

    Bergmann, N. C., Gasbjerg, Lærke Smidt, Heimbürger, S. M., Krogh, L. S. L., Dela, Flemming, Hartmann, Bolette, Holst, Jens Juul, Jessen, L., Christensen, Mikkel Bring, Vilsbøll, Tina, Lund, A. & Knop, Filip Krag, 2020, In: Diabetes Care. 43, 3, p. 588-596 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Semaglutide for the treatment of overweight and obesity: A review

    Bergmann, N. C., Davies, M. J., Lingvay, I. & Knop, Filip Krag, 2023, In: Diabetes, Obesity and Metabolism. 25, 1, p. 18-35

    Research output: Contribution to journal › Review › Research › peer-review

  60. Published

    Separate and Combined Effects of GIP and GLP-1 Infusions on Bone Metabolism in Overweight Men without Diabetes

    Bergmann, N. C., Lund, A., Gasbjerg, Lærke Smidt, Jørgensen, N. R., Jessen, L., Hartmann, Bolette, Holst, Jens Juul, Christensen, Mikkel Bring, Vilsbøll, Tina & Knop, Filip Krag, Jul 2019, In: The Journal of clinical endocrinology and metabolism. 104, 7, p. 2953–2960

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    MRI-Based Quantification of Pan-Alimentary Function and Motility in Subjects with Diabetes and Gastrointestinal Symptoms

    Bertoli, D., Mark, E. B., Liao, D., Okdahl, T., Nauser, S., Daugberg, L. H., Brock, C., Brock, Birgitte, Knop, Filip Krag, Krogh, K., Brøndum Frøkjær, J. & Drewes, A. M., 2023, In: Journal of Clinical Medicine. 12, 18, 16 p., 5968.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Pan-alimentary assessment of motility, luminal content, and structures: an MRI-based framework

    Bertoli, D., Mark, E. B., Liao, D., Brock, C., Brock, Birgitte, Knop, Filip Krag, Krogh, K., Frøkjær, J. B. & Drewes, A. M., 2023, In: Scandinavian Journal of Gastroenterology. 58, 12, p. 1378–1390 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Mapping prohormone processing by proteases in human enteroendocrine cells using genetically engineered organoid models

    Beumer, J., Bauzá-Martinez, J., Veth, T. S., Geurts, V., Boot, C., Gilliam-Vigh, H., Poulsen, Steen Seier, Knop, Filip Krag, Wu, W. & Clevers, H., 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 46, 11 p., e2212057119.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    HYPOGLYCAEMIC EPISODES EVALUATED BY CONTINUOUS GLUCOSE MONITORING IN PATIENTS WITH TYPE 2 DIABETES AND DIALYSIS-DEPENDENT END-STAGE RENAL DISEASE RANDOMISED TO 12-WEEK LIRAGLUTIDE OR PLACEBO TREATMENT

    Bomholt, T., Idorn, T., Knop, Filip Krag, Jorgensen, M. B., Resuli, M., Christensen, Karl Bang, Hansen, P. M., Borg, Rikke, Persson, F., Feldt-Rasmussen, Bo & Hornum, Mads, May 2018, In: Nephrology Dialysis Transplantation. 33, suppl_1, p. 492-492 SP426.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  65. Published

    Glucose variability in maintenance hemodialysis patients with type 2 diabetes: Comparison of dialysis and nondialysis days

    Bomholt, T., Rix, M., Almdal, T., Knop, Filip Krag, Rosthøj, Susanne, Jørgensen, M. B., Feldt-Rasmussen, Bo & Hornum, Mads, 2023, In: Hemodialysis International. 27, 2, p. 126-133 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Reduced erythrocyte lifespan measured by chromium-51 in patients with type 2 diabetes undergoing long-term hemodialysis

    Bomholt, T., Oturai, P., Rix, M., Almdal, Thomas Peter, Knop, Filip Krag, Rosthøj, Susanne, Feldt-Rasmussen, Bo & Hornum, M., 2021, In: Hemodialysis International. 25, 2, p. 198-204 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    The Glycemic Effect of Liraglutide Evaluated by Continuous Glucose Monitoring in Persons with Type 2 Diabetes Receiving Dialysis

    Bomholt, T., Idorn, T., Knop, Filip Krag, Jørgensen, M. B., Ranjan, A. G., Resuli, M., Hansen, P. M., Borg, Rikke, Persson, F., Feldt-Rasmussen, Bo & Hornum, Mads, 2021, In: Nephron. 145, 1, p. 27-34

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Hemoglobin A1c and Fructosamine Evaluated in Patients with Type 2 Diabetes Receiving Peritoneal Dialysis Using Long-Term Continuous Glucose Monitoring

    Bomholt, T., Feldt-Rasmussen, Bo, Butt, Rizwan Ahmed, Borg, Rikke, Sarwary, M. H., Elung-Jensen, T., Almdal, Thomas Peter, Knop, Filip Krag, Nørgaard, Kirsten, Ranjan, A. G., Larsson, A., Rix, M. & Hornum, Mads, 2022, In: Nephron. 146, 2, p. 146-152

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    The Accuracy of Hemoglobin A1c and Fructosamine Evaluated by Long-Term Continuous Glucose Monitoring in Patients with Type 2 Diabetes Undergoing Hemodialysis

    Bomholt, T., Rix, M., Almdal, Thomas Peter, Knop, Filip Krag, Rosthøj, Susanne, Heinrich, N. S., Jørgensen, M. B., Larsson, A., Hilsted, Linda, Feldt-Rasmussen, Bo & Hornum, Mads, 2022, In: Blood Purification. 51, p. 608–616 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    GLYCAEMIC MARKERS IN PATIENTS WITH TYPE 2 DIABETES UNDERGOING HAEMODIALYSIS EVALUATED BY LONG-TERM CONTINUOUS GLUCOSE MONITORING

    Bomholt, T., Rix, M., Almdal, Thomas Peter, Knop, Filip Krag, Rosthøj, Susanne, Heinrich, N. S., Jørgensen, M., Larsson, A., Hilsted, L., Feldt-Rasmussen, Bo & Hornum, Mads, 2021, In: Nephrology Dialysis Transplantation. 36, Supplement 1, p. 371 1 p., MO633.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  71. Published

    Reduced postprandial GLP-1 responses in women with gestational diabetes mellitus

    Bonde, L., Vilsbøll, Tina, Nielsen, T., Bagger, J. I., Svare, J. A., Holst, Jens Juul, Larsen, S. & Knop, Filip Krag, 13 Feb 2013, In: Diabetes, Obesity and Metabolism. 15, 8, p. 713-720 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Restoration of enteroendocrine and pancreatic function after internal hernia and short bowel syndrome in a young woman with gastric bypass: a 2-year follow-up

    Borghede, M., Vinter-Jensen, L., Rasmussen, H. H., Veedfald, Simon, Rehfeld, Jens Frederik, Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag & Sonne, D. P., 2018, In: Physiological Reports. 6, 9, 6 p., e13686.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Prognostic factors of 90-day mortality in patients hospitalised with covid-19

    Brieghel, C., Ellekvist, P., Lund, M. L., Søborg, C., Walsted, E. S., Thomsen, J. J., Biering-Sørensen, Tor, Mohr, T., Knop, Filip Krag & Ravn, Pernille, 2021, In: Danish Medical Journal. 68, 3, p. 1-9 9 p., A09200705.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Liraglutide decreases postprandial fibroblast growth factor 19 and glucagon-like peptide 2, and increases postprandial cholecystokinin in individuals with obesity

    Bronden, A., Nerild, H. H., Nexoe-Larsen, C. C., Hellmann, P. H., Baekdal, M., Gether, I. M., Gillum, M. P., Hartmann, Bolette, Knudsen, L. B., Jacobsen, L. V., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina, Sonne, D. P. & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 94-94 177.

    Research output: Contribution to journal › Conference abstract in journal › Research

  75. Published

    Metformin potentiates bile acid-induced GLP-1 secretion in patients with type 2 diabetes

    Bronden, A., Alber, A., Rohde, U., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Diabetologia. 60, p. 113-113 242.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  76. Published

    Gluco-Metabolic Effects of Pharmacotherapy-Induced Modulation of Bile Acid Physiology

    Bronden, A. & Knop, Filip Krag, 2020, In: Journal of Clinical Endocrinology & Metabolism. 105, 1, p. 362-373

    Research output: Contribution to journal › Review › Research › peer-review

  77. Published

    Sevelamer in a diabetologist's perspective: A phosphate-binding resin with glucose-lowering potential

    Brønden, Andreas, Hansen, M., Sonne, David Peick, Rohde, U., Vilsbøll, Tina & Knop, Filip Krag, 1 Feb 2015, In: Diabetes, Obesity and Metabolism. 17, 2, p. 116-120 5 p.

    Research output: Contribution to journal › Review › Research › peer-review

  78. Published

    Sevelamer in a diabetologist's perspective: A phosphate-binding resin with glucose-lowering potential

    Brønden, Andreas, Hansen, M., Sonne, David Peick, Rohde, U., Vilsbøll, Tina & Knop, Filip Krag, 1 Feb 2015, In: Diabetes, Obesity and Metabolism. 17, 2, p. 116-120 5 p.

    Research output: Contribution to journal › Review › Research › peer-review

  79. Published

    Clinical Pharmacokinetics and Pharmacodynamics of Albiglutide

    Brønden, A., Knop, Filip Krag & Christensen, Mikkel Bring, 2017, In: Clinical Pharmacokinetics. 56, 7, p. 719-731

    Research output: Contribution to journal › Review › Research › peer-review

  80. Published

    Single-Dose Metformin Enhances Bile Acid-Induced Glucagon-Like Peptide-1 Secretion in Patients With Type 2 Diabetes

    Brønden, A., Albér, A., Rohde, U., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Nov 2017, In: The Journal of clinical endocrinology and metabolism. 102, 11, p. 4153-4162 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    The bile acid-sequestering resin sevelamer eliminates the acute GLP-1 stimulatory effect of endogenously released bile acids in patients with type 2 diabetes

    Brønden, A., Albér, A., Rohde, U., Gasbjerg, Lærke Smidt, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 1 Feb 2018, In: Diabetes, Obesity and Metabolism. 20, 2, p. 362-369

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Glucose-lowering effects and mechanisms of the bile acid-sequestering resin sevelamer

    Brønden, A., Mikkelsen, K., Sonne, D. P., Hansen, M., Våben, C., Gabe, M. N., Rosenkilde, Mette, Tremaroli, V., Wu, H., Bäckhed, F., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Jul 2018, In: Diabetes, Obesity and Metabolism. 20, 7, p. 1623-1631

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Albiglutide for treating type 2 diabetes: an evaluation of pharmacokinetics/pharmacodynamics and clinical efficacy

    Brønden, A., Naver, S. V., Knop, Filip Krag & Christensen, M., 2015, In: Expert Opinion on Drug Metabolism & Toxicology. 11, 9, p. 1493-1503 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Changes in oxidative nucleic acid modifications and inflammation following one-week treatment with the bile acid sequestrant sevelamer: Two randomised, placebo-controlled trials

    Brønden, A., Larsen, E. L., Karstoft, K., Henriksen, T., Vilsbøll, Tina, Poulsen, Henrik Enghusen & Knop, Filip Krag, Feb 2020, In: Journal of Diabetes and its Complications. 34, 2, 8 p., 107446.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Prototype of an evidence-based tool to aid individualized treatment for type 2 diabetes

    Buse, J. B., Holst, I., Knop, Filip Krag, Kvist, K., Thielke, D. & Pratley, R., 2021, In: Diabetes, Obesity and Metabolism. 23, 7, p. 1666-1671

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Secretion of glucagon-like peptide-1 in patients with type 2 diabetes mellitus: systematic review and meta-analyses of clinical studies

    Calanna, S., Christensen, M., Holst, Jens Juul, Laferrère, B., Gluud, Lise Lotte, Vilsbøll, Tina & Knop, Filip Krag, May 2013, In: Diabetologia. 56, 5, p. 965-72 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Lipid and liver abnormalities in haemoglobin A1c-defined prediabetes and type 2 diabetes

    Calanna, S., Scicali, R., Di Pino, A., Knop, Filip Krag, Piro, S., Rabuazzo, A. M. & Purrello, F., Jun 2014, In: Nutrition, Metabolism and Cardiovascular Diseases. 24, 6, p. 670-676 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Secretion of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes: systematic review and meta-analysis of clinical studies

    Calanna, S., Christensen, Mikkel Bring, Holst, Jens Juul, Laferrère, B., Gluud, Lise Lotte, Vilsbøll, T. & Knop, Filip Krag, Oct 2013, In: Diabetes Care. 36, 10, p. 3346-52 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Alpha- and beta-cell abnormalities in haemoglobin A1c-defined prediabetes and type 2 diabetes

    Calanna, S., Scicali, R., Di Pino, A., Knop, Filip Krag, Piro, S., Rabuazzo, A. M. & Purrello, F., 2014, In: Acta Diabetologica. 51, 4, p. 567-575

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Adverse drug reactions associated with the use of liraglutide in patients with type 2 diabetes-focus on pancreatitis and pancreas cancer

    Chalmer, T., Almdal, Thomas Peter, Vilsbøll, Tina & Knop, Filip Krag, 2015, In: Expert Opinion on Drug Safety. 14, 1, p. 171-180

    Research output: Contribution to journal › Review › Research › peer-review

  91. Published

    Efficacy and Safety of Glimepiride With or Without Linagliptin Treatment in Patients With HNF1A Diabetes (Maturity-Onset Diabetes of the Young Type 3): A Randomized, Double-Blinded, Placebo-Controlled, Crossover Trial (GLIMLINA)

    Christensen, A. S., Haedersdal, S., Stoy, J., Storgaard, H., Kampmann, U., Forman, Julie Lyng, Seghieri, M., Holst, Jens Juul, Hansen, Torben, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Diabetes Care. 43, 9, p. 2025-2033 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    GIP and GLP-1 Potentiate Sulfonylurea-Induced Insulin Secretion in HNF1A Diabetes

    Christensen, A. S., Haedersdal, S., Storgaard, H., Rose, K., Hansen, N. L., Holst, Jens Juul, Hansen, Torben, Knop, Filip Krag & Vilsbøll, Tina, 2019, In: Diabetes. 68, Suppl. 1, 1 p., 981-P.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  93. Published

    GIP and GLP-1 Potentiate Sulfonylurea-Induced Insulin Secretion in Hepatocyte Nuclear Factor 1 alpha Mutation Carriers

    Christensen, A. S., Haedersdal, S., Storgaard, H., Rose, K., Hansen, N. L., Holst, Jens Juul, Hansen, Torben, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Diabetes. 69, 9, p. 1989-2002 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Glimepiride monotherapy versus combination of glimepiride and linagliptin therapy in patients with HNF1A-diabetes: a protocol for a randomised, double-blinded, placebo-controlled trial

    Christensen, A. S., Storgaard, H., Hædersdal, S., Hansen, Torben, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: BMJ Open. 8, p. 1-9 e022517.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Transfer of liraglutide from blood to cerebrospinal fluid is minimal in patients with type 2 diabetes

    Christensen, M., wbf943, wbf943, Hartmann, Bolette, Grevstad, U., Rosenkilde, Mette, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Nov 2015, In: International journal of obesity (2005). 39, 11, p. 1651-1654 4 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  96. Published

    The design and discovery of lixisenatide for the treatment of type 2 diabetes mellitus

    Christensen, M., Miossec, P., Larsen, B. D., Werner, U. & Knop, Filip Krag, 2014, In: Expert Opinion on Drug Discovery. 9, 10, p. 1223-1251 29 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Once-weekly GLP-1 agonists: How do they differ from exenatide and liraglutide?

    Christensen, M. & Knop, Filip Krag, 1 Apr 2010, In: Current Diabetes Reports. 10, 2, p. 124-32 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Lixisenatide for type 2 diabetes mellitus

    Christensen, M., Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 2011, In: Expert Opinion on Investigational Drugs. 20, 4, p. 549-57 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    The alpha-cell as target for type 2 diabetes therapy

    Christensen, M., Bagger, J. I., Vilsbøll, Tina & Knop, Filip Krag, 2011, In: Review of Diabetic Studies. 8, 3, p. 369-81 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Lixisenatide, a novel GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus

    Christensen, M., Knop, Filip Krag, Holst, Jens Juul & Vilsboll, T., 2009, In: IDrugs. The Investigational Drugs Journal. 12, 8, p. 503-13 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 40100368