Filip Krag Knop
Clinical Professor
Department of Clinical Medicine
Borgmester Ib Juuls Vej 1, 2730 Herlev
Member of:
Internal Medicine: Endocrinology
- Published
Use of antibiotics in childhood and risk of Type 1 diabetes: a population-based case-control study
Mikkelsen, K. H., Knop, Filip Krag, Vilsbøll, Tina, Frost, M., Hallas, J. & Pottegård, A., Feb 2017, In: Diabetic Medicine. 34, 2, p. 272–277Research output: Contribution to journal › Journal article › Research › peer-review
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Influenza vaccination is associated with reduced cardiovascular mortality in adults with diabetes: A nationwide cohort study
Modin, D., Claggett, B., Køber, Lars Valeur, Schou, Morten, Jensen , Jens-Ulrik Stæhr , Solomon, S. D., Vardeny, O., Knop, Filip Krag, Nielsen, Susanne Dam, Fralick, M., Torp-Pedersen, Christian, Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2020, In: Diabetes Care. 43, 9, p. 2226-2233 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dyslipidæmi ved psykisk lidelse
Mohr, G. H., Barcella, C. A., Coello, K., Baandrup, Lone & Knop, Filip Krag, 2022, In: Ugeskrift for Laeger. 184, 10, 10 p., V05210439.Research output: Contribution to journal › Journal article › Research › peer-review
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Management of people with Type 2 diabetes shared between a specialized outpatient clinic and primary health care is noninferior to management in a specialized outpatient clinic: a randomized, noninferiority trial
Munch, L., Bennich, B. B., Overgaard, D., Konradsen, H., Middelfart, H., Kaarsberg, N., Knop, Filip Krag, Vilsbøll, Tina & Røder, M. E., 2019, In: Diabetic Medicine. 36, 7, p. 854-861Research output: Contribution to journal › Journal article › Research › peer-review
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Management of Patients with Type 2 Diabetes Shared between a Specialized Outpatient Clinic and General Practice Was Noninferior to Mono Management in a Specialized Outpatient Clinic—A Prospective, Randomized, Noninferiority Trial
Munch, L., Bennich, B. B., Overgaard, D., Konradsen, Hanne, Middelfart, H. V., Kaarsberg, N., Knop, Filip Krag, Vilsbøll, Tina & Røder, M., 2018, In: Diabetes. 67, Supplement 1, 6-OR.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Tværsektorielt samarbejde ved behandling af patienter med type 2-diabetes
Munch, L., Røder, M. E., Rasmussen, I. H., Middelfart, H., Kaarsberg, N., Bennich, B., Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Ugeskrift for Laeger. 180, 8, p. 690-693Research output: Contribution to journal › Journal article › Research › peer-review
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Risk stratification by endocrinologists of patients with type 2 diabetes in a Danish specialised outpatient clinic: a cross-sectional study
Munch, L., Arreskov, Anne Beiter, Sperling, M., Overgaard, D., Knop, Filip Krag, Vilsbøll, Tina & Røder, M. E., 2016, In: BMC Health Services Research. 16, 10 p., 124.Research output: Contribution to journal › Journal article › Research › peer-review
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Shared care management of patients with type 2 diabetes across the primary and secondary healthcare sectors: study protocol for a randomised controlled trial
Munch, L., Bennich, B., Arreskov, Anne Beiter, Overgaard, D., Konradsen, H., Knop, Filip Krag, Vilsbøll, Tina & Røder, M. E., 2016, In: Trials. 17, 10 p., 277.Research output: Contribution to journal › Journal article › Research › peer-review
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Gastrisk aspirationsbehandling er et muligt alternativ til behandling af fedme
Møller Christensen, M., Jorsal, T., Naver, L. P. S., Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Ugeskrift for Laeger. 179, 32, 4 p., V03170198.Research output: Contribution to journal › Journal article › Research › peer-review
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The glucose-lowering effect of the bile acid sequestrant sevelamer in patients with type 2 diabetes is not mediated by glucagon-like peptide 1
Nerild, H. H., Brønden, Andreas, Haddouchi, A. E., Holst, Jens Juul, Sonne, D. P., Vilsbøll, Tina & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 217-217 422.Research output: Contribution to journal › Conference abstract in journal › Research
- E-pub ahead of print
Expression of bile acid receptors and transporters along the intestine of patients with type 2 diabetes and controls
Nerild, H. H., Gilliam-Vigh, H., Ellegaard, A., Forman, Julie Lyng, Vilsbøll, Tina, Sonne, David Peick, Brønden, Andreas & Knop, Filip Krag, 2024, (E-pub ahead of print) In: The Journal of clinical endocrinology and metabolism.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liraglutide changes postprandial responses of gut hormones involved in the regulation of gallbladder motility
Nerild, H. H., Brønden, Andreas, Gether, I. M., Hellmann, P. H., Baekdal, M., Gillum, M. P., Svenningsen, J. S., Hartmann, Bolette, Rathor, N., Kudiyanur Muniraju, H. A., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina, Sonne, David Peick & Knop, Filip Krag, 2023, In: Diabetes, Obesity and Metabolism. 25, 6, p. 1632-1637Research output: Contribution to journal › Journal article › Research › peer-review
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Elucidating the glucose-lowering effect of the bile acid sequestrant sevelamer
Nerild, H. H., Brønden, A., Haddouchi, A. E., Ellegaard, A., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul, Sonne, David Peick, Vilsbøll, Tina & Knop, Filip Krag, 2024, In: Diabetes, Obesity and Metabolism. 26, 4, p. 1252-1263Research output: Contribution to journal › Journal article › Research › peer-review
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Preclinical discovery and development of colesevelam for the treatment of type 2 diabetes
Nerild, H. H., Christensen, Mikkel Bring, Knop, Filip Krag & Brønden, A., 2018, In: Expert Opinion on Drug Discovery. 13, 12, p. 1161-1167 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of liraglutide on gallbladder emptying: A randomized, placebo-controlled trial in adults with overweight or obesity
Nexoe-Larsen, C. C., Sorensen, P. H., Hausner, H., Agersnap, M., Baekdal, M., Bronden, A., Gustafsson, L. N., Sonne, David Peick, Vedtofte, L., Vilsbøll, Tina & Knop, Filip Krag, 2018, In: Diabetes, Obesity and Metabolism. 20, 11, p. 2557-2564Research output: Contribution to journal › Journal article › Research › peer-review
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Dasiglucagon Effectively Mitigates Postbariatric Postprandial Hypoglycemia: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial
Nielsen, C. K., Øhrstrøm, C. C., Kielgast, U. L., Hansen, D. L., Hartmann, Bolette, Holst, Jens Juul, Lund, Asger Bach, Vilsbøll, Tina & Knop, Filip Krag, 2022, In: Diabetes Care. 45, 6, p. 1476–1481Research output: Contribution to journal › Journal article › Research › peer-review
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Dasiglucagon Treatment for Postprandial Hypoglycemia After Gastric Bypass: A Randomized, Double-Blind, Placebo-Controlled Trial
Nielsen, C. K., Øhrstrøm, C. C., Houji, I. J. K., Helsted, M. M., Krogh, L. S. L., Johansen, N. J., Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: Diabetes Care. 46, 12, p. 2208-2217 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Weight loss for overweight and obese individuals with gout: a systematic review of longitudinal studies
Nielsen, S. M., Bartels, E. M., Henriksen, Marius, Wæhrens, E. E., Gudbergsen, Henrik Rindel, Bliddal, Henning, Astrup, A., Knop, Filip Krag, Carmona, L., Taylor, W. J., Singh, J. A., Perez-Ruiz, F., Kristensen, Lars Erik Vølund & Christensen, R., 2017, In: Annals of the Rheumatic Diseases. 76, 11, p. 1870-1882 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucose-dependent insulinotropic polypeptide inhibits bone resorption in humans
Nissen, A., Christensen, Mikkel Bring, Knop, Filip Krag, Vilsbøll, T., Holst, Jens Juul & Hartmann, Bolette, Nov 2014, In: The Journal of clinical endocrinology and metabolism. 99, 11, p. E2325-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease
Niu, Lili, Geyer, P. E., Albrechtsen, Nicolai Jacob Wewer, Gluud, Lise Lotte, Santos, A., Doll, S., Treit, P. V., Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina, Junker, A., Sachs, S., Stemmer, K., Müller, T. D., Tschöp, M. H., Hofmann, S. M. & Mann, Matthias, 2019, In: Molecular Systems Biology. 15, 16 p., e8793.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma proteome profiling discovers potential biomarkers of non-alcoholic fatty liver disease
Niu, Lili, Gupta, R., Geyer, P. E., Albrechtsen, Nicolai Jacob Wewer, Gluud, Lise Lotte, Santos, A., Doll, S., Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina, Junker, A., Sachs, S., Stemmer, K., Mueller, T. D., Tschoep, M. H., Hofmann, S. M. & Mann, Matthias, Aug 2019, In: Molecular & Cellular Proteomics. 18, 8, p. S71 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
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Recovery of the incretin effect in type 2 diabetic patients after biliopancreatic diversion
Novaes, F. S., Vasques, A. C. J., Pareja, J. C., Knop, Filip Krag, Tura, A., Chaim, É. A. & Geloneze, B., 1 May 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 5, p. 1984-1988 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Recovery of the incretin effect in type 2 diabetic patients after biliopancreatic diversion
Novaes, F. S., Vasques, A. C. J., Pareja, J. C., Knop, Filip Krag, Tura, A., Chaim, É. A. & Geloneze, B., 1 May 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 5, p. 1984-1988 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Study protocol for a multicentre, randomised, parallel group, sham-controlled clinical trial investigating the effect of transcutaneous vagal nerve stimulation on gastrointestinal symptoms in people with diabetes complicated with diabetic autonomic neuropathy: The DAN-VNS Study
Okdahl, T., Bertoli, D., Brock, Birgitte, Krogh, K., Knop, Filip Krag, Brock, C. & Drewes, A. M., 2021, In: BMJ Open. 11, 1, e038677.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The incretin effect in patients with maturity onset diabetes of the young
Ostoft, S. H., Bagger, J. I., Hansen, T., Pedersen, O., Holst, Jens Juul, Knop, Filip Krag & Vilsboll, T., 2012, In: Diabetologia. 55, p. S144-S144Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-Lowering Effects and Low Risk of Hypoglycemia in Patients With Maturity-Onset Diabetes of the Young When Treated With a GLP-1 Receptor Agonist: A Double-Blind, Randomized, Crossover Trial
Ostoft, S. H., Bagger, J. I., Hansen, Torben, Pedersen, Oluf Borbye, Faber, Jens, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 14 Jun 2014, In: Diabetes Care. 37, 7, p. 1797-1805 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Incretin Effect and Glucagon Responses to Oral and Intravenous Glucose in Patients with Maturity Onset Diabetes of the Young - Type 2 and Type 3
Ostoft, S. H., Bagger, J. I., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 27 Mar 2014, In: Diabetes. 63, 8, p. 2838-44 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Recovery of gut microbiota of healthy adults following antibiotic exposure
Palleja, A., Mikkelsen, K. H., Forslund, S. K., Kashani, A., Allin, K. H., Nielsen, T., Hansen, T. H., Liang, S., Feng, Q., Zhang, C., Pyl, P. T., Coelho, L. P., Yang, H., Wang, J., Typas, A., Nielsen, M. F., Nielsen, H. B., Bork, P., Wang, J., Vilsbøll, T. & 4 others, , Nov 2018, In: Nature Microbiology. 3, 11, p. 1255-1265 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cardiovascular effects of high-dose glucagon: a randomised clinical trial
Petersen, K. M., Bogevig, S., Riis, T., Andersson, N. A. W., Dalhoff, Kim, Holst, Jens Juul, Knop, Filip Krag, Faber, Jens, Petersen, Tonny Studsgaard & Christensen, Mikkel Bring, 2020, In: Diabetologia. 63, SUPPL 1, p. S231-S231Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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High-Dose Glucagon Has Hemodynamic Effects Regardless of Cardiac Beta-Adrenoceptor Blockade: A Randomized Clinical Trial
Petersen, K. M., Bøgevig, S., Riis, T., Andersson, N. W., Dalhoff, Kim, Holst, Jens Juul, Knop, Filip Krag, Faber, Jens, Petersen, Tonny Studsgaard & Christensen, Mikkel Bring, 2020, In: Journal of the American Heart Association. 9, 21, 27 p., e016828.Research output: Contribution to journal › Journal article › Research › peer-review
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Hemodynamic Effects of Glucagon: A Literature Review
Petersen, K. M., Bogevig, S., Holst, Jens Juul, Knop, Filip Krag & Christensen, Mikkel Bring, 2018, In: Journal of Clinical Endocrinology & Metabolism. 103, 5, p. 1804-1812Research output: Contribution to journal › Review › Research › peer-review
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Response to Letter to the Editor: "Hemodynamic Effects of Glucagon: A Literature Review"
Petersen, K. M., Bøgevig, S., Holst, Jens Juul, Knop, Filip Krag & Christensen, Mikkel Bring, 2018, In: The Journal of clinical endocrinology and metabolism. 103, 12, p. 4480-4481 2 p.Research output: Contribution to journal › Comment/debate › Research
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Characterization of oral and intravenous glucose handling in truncally vagotomised subjects with pyloroplasty
Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Wettergren, A., Svendsen, Lars Bo, Meisner, S., Hovendal, C., Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 23 May 2013, In: European Journal of Endocrinology. 169, p. 187-201 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The role of efferent cholinergic transmission for the insulinotropic and glucagonostatic effects of GLP-1
Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Vilsbøll, T., Knop, Filip Krag & Holst, Jens Juul, Sep 2015, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 309, 5, p. R544-51 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Effect of Exogenous GLP-1 on Food Intake is Lost in Male Truncally Vagotomized Subjects with Pyloroplasty
Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Wettergren, A., Svendsen, Lars Bo, Meisner, S., Hovendahl, C., Vilsbøll, Tina, Knop, Filip Krag & Holst, Jens Juul, 18 Apr 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 304, p. G1117-G1127 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Use of exenatide and liraglutide in Denmark: A drug utilization study
Pottegård, A., Bjerregaard, B. K., Larsen, M. D., Larsen, K. S., Hallas, J., Knop, Filip Krag & Moreno, S. I., Feb 2014, In: European Journal of Clinical Pharmacology. 70, 2, p. 205-214 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Semaglutide for the treatment of antipsychotic-associated weight gain in patients not responding to metformin - a case series
Prasad, F., De, R., Korann, V., Chintoh, A. F., Remington, G., Ebdrup, Bjørn, Siskind, D., Knop, Filip Krag, Vilsbøll, Tina, Fink-Jensen, Anders, Hahn, M. K. & Agarwal, S. M., 2023, In: Therapeutic Advances in Psychopharmacology. 13, 10 p., 20451253231165169.Research output: Contribution to journal › Journal article › Research › peer-review
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Targeting the GLP-2 receptor in the management of obesity
Pálsson, T. G., Gilliam-Vigh, Hannah, Jensen, Benjamin Anderschou Holbech, Jeppesen, Palle Bekker, Lund, Asger Bach, Knop, Filip Krag & Nielsen, C. K., 2024, In: Peptides. 177, 9 p., 171210.Research output: Contribution to journal › Review › Research › peer-review
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Value of gym-based group exercise versus usual care for young adults receiving antipsychotic medication: study protocol for the multicenter randomized controlled Vega trial
Rafn, B. S., Andersen, M. F., Sørensen, V., Bjerre, E. D., Baandrup, Lone, Vernal, D. L., Mors, O., Knop, Filip Krag, Wolf, R. T., Tolver, Anders, Firth, J., Nøhr, N., Skou, S. T., Ebdrup, Bjørn & Midtgaard, Julie, 2023, In: BMC Psychiatry. 23, 1, 13 p., 634.Research output: Contribution to journal › Journal article › Research › peer-review
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Systemic corticosteroids and the risk of venous thromboembolism in patients with severe copd: A nationwide study of 30, 473 outpatients
Rastoder, E., Sivapalan, P., Eklöf, J., Saeed, M. I., Jordan, A. S., Meteran, H., Tønnesen, L., Biering-Sørensen, T., Løkke, A., Seersholm, N., Nielsen, T. L., Carlsen, J., Janner, J., Godtfredsen, N., Bodtger, U., Laursen, C. B., Hilberg, O., Knop, F. K., Priemé, H., Ingebrigtsen, T. S. & 3 others, , 2021, In: Biomedicines. 9, 8, 874.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cholecystokinin secretion is suppressed by glucagon-like peptide-1: clue to the mechanism of the adverse gallbladder events of GLP-1-derived drugs
Rehfeld, Jens Frederik, Knop, Filip Krag, Asmar, A., Madsbad, Sten, Holst, Jens Juul & Asmar, M., 2018, In: Scandinavian Journal of Gastroenterology. 53, 12, p. 1429-1432Research output: Contribution to journal › Journal article › Research › peer-review
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Gastrin secretion in normal subjects and diabetes patients is inhibited by glucagon-like peptide 1: a role in the gastric side effects of GLP-1-derived drugs?
Rehfeld, Jens Frederik, Knop, Filip Krag & Asmar, M., 2019, In: Scandinavian Journal of Gastroenterology. 54, 12, p. 1448-1451 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Current evidence for a role of GLP-1 in Roux-en-Y gastric bypass-induced remission of type 2 diabetes
Rhee, N. A., Vilsbøll, Tina & Knop, Filip Krag, 2012, In: Diabetes, Obesity and Metabolism. 14, 4, p. 291-298Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of Roux-en-Y gastric bypass on the distribution and hormone expression of small-intestinal enteroendocrine cells in obese patients with type 2 diabetes
Rhee, N. A., Wahlgren, C. D., Pedersen, J., Mortensen, B., Langholz, E., Wandall, E. P., Friis, S. U., Vilmann, Peter, Paulsen, S. J., Kristiansen, V. B., Jelsing, J., Dalbøge, L. S., Poulsen, Steen Seier, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, 2015, In: Diabetologia. 58, 10, p. 2254-2258 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
The impact of dipeptidyl peptidase 4 inhibition on incretin effect, glucose tolerance, and gastrointestinal-mediated glucose disposal in healthy subjects
Rhee, N. A., Østoft, S. H., Holst, Jens Juul, Deacon, Carolyn F., Vilsbøll, T. & Knop, Filip Krag, 16 Jun 2014, In: European Journal of Endocrinology. 171, 3, p. 353-362 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The use of double-balloon enteroscopy in retrieving mucosal biopsies from the entire human gastrointestinal tract
Rhee, N. A., Vilmann, Peter, Hassan, H., Hendel, J. W., Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Sep 2014, In: Scandinavian Journal of Gastroenterology. 49, 9, p. 1143-1149 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Liver-Alpha Cell Axis in Health and in Disease
Richter, Michael Martin, Galsgaard, Katrine Douglas, Elmelund, E., Knop, Filip Krag, Suppli, M. P., Holst, Jens Juul, Winther-Sørensen, Marie, Kjeldsen, Sasha Alexandra Sampson & Albrechtsen, Nicolai Jacob Wewer, 2022, In: Diabetes. 71, +, p. 1852–1861Research output: Contribution to journal › Review › Research › peer-review
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Clinical translatability of a diet-induced obese mouse model of non-alcoholic steatohepatitis
Rigbolt, K., Veidal, S., Suppli, M., Eriksen, P. L., Feigh, M., Knop, Filip Krag, Gronbaek, H., Thomsen, K. L., Jelsing, J. & Vrang, N., 2019, In: Journal of Hepatology. 70, 1, p. E544 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Hypothyroid women have persistently higher oxidative stress compared to healthy controls
Riis, K. R., Larsen, C. B., Medici, B. R., Jensen, C. Z., Winther, K. H., Larsen, E. L., Ellervik, Christina, la Cour, J. L., Hegedüs, L., Brix, T. H., Poulsen, Henrik Enghusen, Knop, Filip Krag, Nygaard, Birte & Bonnema, S. J., 2023, In: European Thyroid Journal. 12, 6, 10 p., e230167.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma YKL-40 during pregnancy and gestational diabetes mellitus
Rinnov, A. R., Rathcke, C. N., Bonde, L., Vilsbøll, Tina & Knop, Filip Krag, 2015, In: Journal of Reproductive Immunology. 112, p. 68-72Research output: Contribution to journal › Journal article › Research › peer-review
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Increased glucagon sensitivity in totally pancreatectomised patients
Rix, I., Lund, A., Garvey, Lene Heise, Owen, K., Hansen, C., van Hall, Gerrit, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 118-119 226.Research output: Contribution to journal › Conference abstract in journal › Research
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Hyperglucagonaemia and amino acid alterations in individuals with type 2 diabetes and non-alcoholic fatty liver disease
Rix, I., Johansen, M. L., Lund, A., Suppli, M. P., Chabanova, E., van Hall, Gerrit, Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Kistorp, Caroline Michaela Nervil & Knop, Filip Krag, 2023, In: Endocrine Connections. 13, 1, 11 p., e230161.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of the EndoBarrier Gastrointestinal Liner on obesity and type 2 diabetes: a systematic review and meta-analysis
Rohde, U., Hedbäck, N., Gluud, Lise Lotte, Vilsbøll, Tina & Knop, Filip Krag, Mar 2016, In: Diabetes, Obesity and Metabolism. 18, 3, p. 300-5 6 p.Research output: Contribution to journal › Letter › Research › peer-review
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Premature explantation of an EndoBarrier gastrointestinal liner because of sleeve invagination
Rohde, U., Federspiel, C. A., Vilmann, Peter, Friis, S. U., Langholz, E., Vilsbøll, Tina & Knop, Filip Krag, 2015, In: Endoscopy. 47 , Suppl 1 , p. E275-6 2 p.Research output: Contribution to journal › Letter › Research › peer-review
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The impact of EndoBarrier gastrointestinal liner in obese patients with normal glucose tolerance and in patients with type 2 diabetes
Rohde, U., Federspiel, C. A., Vilmann, Peter, Langholz, Ebbe, Friis, S. U., Krakauer, M., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Feb 2017, In: Diabetes, Obesity and Metabolism. 19, 2, p. 189-199 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of the EndoBarrier Gastrointestinal Liner on obesity and type 2 diabetes: protocol for systematic review and meta-analysis of clinical studies
Rohde, U., Hedbäck, N., Gluud, Lise Lotte, Vilsbøll, T. & Knop, Filip Krag, 2013, In: B M J Open. 3, 9, p. 1-5 e003417.Research output: Contribution to journal › Journal article › Research › peer-review
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Cholecystokinin-Induced Gallbladder Emptying and Single-Dose Metformin Elicit Additive Glucagon-Like Peptide-1 Responses
Rohde, U., Sonne, D. P., Christensen, M., Hansen, M., Brønden, A., Toräng, S., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 1 May 2016, In: The Journal of clinical endocrinology and metabolism. 101, 5, p. 2076-2083Research output: Contribution to journal › Journal article › Research › peer-review
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Behandling med duodenal-jejunal bypass-sleeve ved svær overvægt
Rohde, U., Gylvin, S., Vilmann, Peter, Friis, S. U., Langholz, Ebbe, Vilsbøll, T. & Knop, Filip Krag, 29 Sep 2014, In: Ugeskrift for Laeger. 176, 37, p. 1874-1877 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Diagnostik og behandling af maturity onset diabetes of the young type 3
Rose, K., Christensen, A. S., Storgaard, H., Hædersdal, S., Hansen, Torben, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Ugeskrift for Laeger. 180, 6 p., V06170502.Research output: Contribution to journal › Journal article › Research › peer-review
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Greater time spent with HbA1c less than 7.0% with oral semaglutide versus oral comparators: An exploratory analysis of the PIONEER studies
Rosenstock, J., Cariou, B., Eliasson, J., Frappin, G., Kaltoft, M. S., Montanya, E. & Knop, Filip Krag, 2024, In: Diabetes, Obesity and Metabolism. 26, 2, p. 532-539 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sodium-glucose cotransporter 2 (SGLT-2) inhibitors for patients with Type 2 diabetes
Røder, M. E., Storgaard, H., Rungby, Jørgen, Knop, Filip Krag & Vilsbøll, Tina, 19 Sep 2016, In: Ugeskrift for Laeger. 178, 38Research output: Contribution to journal › Review › Research › peer-review
- Published
Sodium-glucose cotransporter (SGLT)-2-inhibitorer til patienter med type 2-diabetes
Røder, M. E., Storgaard, H., Rungby, J., Knop, Filip Krag & Vilsbøll, Tina, 26 Dec 2016, In: Ugeskrift for Laeger. 178, 26, p. 2461-64 V05160310.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sodium-glucose cotransporter 2 (SGLT-2) inhibitors for patients with Type 2 diabetes
Røder, M. E., Storgaard, H., Rungby, Jørgen, Knop, Filip Krag & Vilsbøll, Tina, 19 Sep 2016, In: Ugeskrift for Laeger. 178, 38Research output: Contribution to journal › Review › Research › peer-review
- Published
Mathematical Modelling of Glucose-Dependent Insulinotropic Polypeptide and Glucagon-like Peptide-1 following Ingestion of Glucose
Røge, R. M., Bagger, J. I., Alskär, O., Kristensen, N. R., Klim, S., Holst, Jens Juul, Ingwersen, S. H., Karlsson, M. O., Knop, Filip Krag, Vilsbøll, Tina & Kjellsson, M. C., Oct 2017, In: Basic & Clinical Pharmacology & Toxicology. 121, 4, p. 290-297 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of inhaled corticosteroids and the risk of developing type 2 diabetes in patients with chronic obstructive pulmonary disease
Saeed, M. I., Eklof, J., Achir, I., Sivapalan, P., Meteran, Howraman, Lokke, A., Biering-Sørensen, Tor, Knop, Filip Krag & Jensen , Jens-Ulrik Stæhr , 2020, In: Diabetes, Obesity and Metabolism. 22, 8, p. 1348-1356 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretion of parathyroid hormone may be coupled to insulin secretion in humans
Sass, M. R., Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Hare, Kristine Juul, Borbye-Lorenzen, N., Kiss, K., Vilsbøll, Tina, Knop, Filip Krag, Poulsen, Steen Seier, Jørgensen, Niklas Rye, Holst, Jens Juul, Ørskov, Cathrine & Hartmann, Bolette, 2020, In: Endocrine Connections. 9, 7, p. 747-754Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of the GLP-1 receptor agonist semaglutide on metabolic disturbances in clozapine-treated or olanzapine-treated patients with a schizophrenia spectrum disorder: study protocol of a placebo-controlled, randomised clinical trial (SemaPsychiatry)
Sass, M. R., Danielsen, A. A., Köhler-Forsberg, O., Storgaard, H., Knop, Filip Krag, Nielsen, Mette Ødegaard, Sjödin, Anders Mikael, Mors, O., Correll, C. U., Ekstrøm, Claus Thorn, Vinberg, Maj, Nielsen, Jimmi, Vilsbøll, Tina & Fink-Jensen, Anders, 2023, In: BMJ Open. 13, 1, 10 p., e068652.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells
Schisler, J. C., Jensen, P. B., Harper, D. A. T., Becker, T., Knop, Filip Krag, Takekawa, S., German, M., Weir, G. C., Lu, D., Mirmira, R. G. & Newgard, C. B., 17 May 2005, In: Proceedings of the National Academy of Sciences of the United States of America. 102, 20, p. 7297-302 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of sitagliptin on counterregulatory and incretin hormones during acute hypoglycaemia in patients with type 1 diabetes: a randomized double blind placebo-controlled cross-over study
Schopman, J. E., Hoekstra, J. B. L., Frier, B. M., Ackermans, M. T., de Sonnaville, J. J. J., Stades, A. M., Zwertbroek, R., Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag & Holleman, F., Jun 2015, In: Diabetes, Obesity and Metabolism. 17, 6, p. 546-53 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Future Perspectives on GLP-1 Receptor Agonists and GLP-1/glucagon Receptor Co-agonists in the Treatment of NAFLD
Seghieri, M., Christensen, A. S., Andersen, A., Solini, A., Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Frontiers in Endocrinology. 9, p. 1-10 649.Research output: Contribution to journal › Review › Research › peer-review
- Published
Glucagon-like peptide-1 receptor agonists for antipsychotic-associated cardio-metabolic risk factors: a systematic review and individual participant data meta-analysis
Siskind, D., Hahn, M., Correll, C. U., Fink-Jensen, Anders, Russell, A. W., Bak, N., Broberg, B. V., Larsen, J., Ishoy, P. L., Vilsbøll, Tina, Knop, Filip Krag, Kisely, S. & Ebdrup, Bjørn, 2019, In: Diabetes, Obesity and Metabolism. 21, 2, p. 293-302 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Azithromycin and hydroxychloroquine in hospitalised patients with confirmed COVID-19: a randomised double-blinded placebo-controlled trial
Sivapalan, P. & ProPAC-COVID writing group on behalf of the ProPAC-COVID Study Group, P. W. G. O. B. O. T. P. S. G., 2022, In: European Respiratory Journal. 59, 1, 2100752.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proactive prophylaxis with azithromycin and hydroxychloroquine in hospitalized patients with COVID-19 (ProPAC-COVID): a statistical analysis plan
Sivapalan, P., Ulrik, Charlotte Suppli, Lappere, T. S., Eklöf, J. V., Shaker, Saher Burhan, Bødtger, U. C. S., Browatzki, A., Meyer, Christian, Weinreich, U. M., Laursen, C. B., Biering-Sørensen, Tor, Knop, Filip Krag, Lundgren, Jens & Jensen , Jens-Ulrik Stæhr , 2020, In: Trials. 21, 1, 867.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proactive Prophylaxis With Azithromycin and HydroxyChloroquine in Hospitalised Patients With COVID-19 (ProPAC-COVID): A structured summary of a study protocol for a randomised controlled trial
Sivapalan, P., Ulrik, C. S., Bojesen, R. D., Lapperre, T. S., Eklöf, J. V., Håkansson, K. E. J., Browatzki, A., Tidemansen, C., Wilcke, J. T., Janner, J., Gottlieb, V., Meteran, H., Porsbjerg, C., Madsen, B. L., Moberg, M., Pedersen, L., Benfield, T. L., Lundgren, J. D., Knop, F. K., Biering-Sørensen, T. & 13 others, , 2020, In: Trials. 21, 4 p., 513.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Myocardial Impairment and Acute Respiratory Distress Syndrome in Hospitalized Patients With COVID-19: The ECHOVID-19 Study
Skaarup, K. G., Lassen, M. C. H., Lind, J. N., Alhakak, A. S., Sengeløv, M., Nielsen, A. B., Espersen, C., Hauser, R., Schöps, L. B., Holt, E., Johansen, N. D., Modin, D., Sharma, S., Graff, C., Bundgaard, H., Hassager, C., Jabbari, R., Lebech, A. M., Kirk, O., Bødtger, U. & 22 others, , 2020, In: JACC: Cardiovascular Imaging. 13, 11, p. 2474-2476 3 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Diabetes and obesity treatment based on dual incretin receptor activation: ‘twincretins’
Skow, M. A., Bergmann, N. C. & Knop, Filip Krag, Sep 2016, In: Diabetes, Obesity and Metabolism. 18, 9, p. 847-54 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Comment on Xu et al. Effects of Metformin on Metabolite Profiles and LDL Cholesterol in Patients With Type 2 Diabetes
Sonne, David Peick & Knop, Filip Krag, Dec 2015, In: Diabetes Care. 38, 12, p. e215 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
On the role of gallbladder emptying and incretin hormones for nutrient-mediated TSH suppression in patients with type 2 diabetes
Sonne, David Peick, Lund, Asger Bach, Faber, J., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Dec 2014, In: Endocrine Connections. 3, 4, p. 193-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial Plasma Concentrations of Individual Bile Acids and FGF-19 in Patients With Type 2 Diabetes
Sonne, David Peick, van Nierop, F. S., Kulik, W., Soeters, M. R., Vilsbøll, Tina & Knop, Filip Krag, Aug 2016, In: Endocrinology. 101, 8, p. 3002-3009 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pancreatic Amylase and Lipase Plasma Concentrations Are Unaffected by Increments in Endogenous GLP-1 Levels Following Liquid Meal Tests
Sonne, David Peick, Vilsbøll, T. & Knop, Filip Krag, 2015, In: Diabetes Care. 38, 5, p. e71-2 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial gut hormone responses and glucose metabolism in cholecystectomized patients
Sonne, D. P., Hare, K. J., Martens, P., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 15 Feb 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 304, 4, p. G413-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial gallbladder emptying in patients with type 2 diabetes: potential implications for bile-induced secretion of glucagon-like peptide 1
Sonne, David Peick, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Oct 2014, In: European Journal of Endocrinology. 171, 4, p. 407-419 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial Plasma Concentrations of ProANP in Patients with Type 2 Diabetes and Healthy Controls
Sonne, D. P., Terzic, D., Knop, Filip Krag & Goetze, Jens P. , May 2017, In: Clinical Chemistry. 63, 5, p. 1040-1041 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Species-specific action of (Pro3)GIP - an efficacious agonist on human GIP receptor, but partial agonist and competitive antagonist on rat and mouse GIP receptors
wbf943, wbf943, Gasbjerg, Lærke Smidt, Svendsen, B., Christensen, M., Knop, Filip Krag, Hartmann, Bolette, Holst, Jens Juul & Rosenkilde, Mette, Jan 2016, In: British Journal of Pharmacology. 173, 1, p. 27-38 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vagotomy and subsequent development of diabetes: A nested case-control study
Starup-Linde, J., Gejl, M., Borghammer, P., Knop, Filip Krag, Gregersen, S., Rungby, Jørgen & Vestergaard, P., Jul 2016, In: Metabolism. 65, 7, p. 954-960 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose-dependent insulinotropic polypeptide (GIP) contributes to sitagliptin-mediated improvement of beta cell function in patients with type 2 diabetes
Stensen, S., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Hartmann, Bolette, Vilsbøll, Tina, Holst, Jens Juul, Christensen, M. B. & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 95-95 179.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Endogenous glucose-dependent insulinotropic polypeptide exerts diverging and tissue specific in obese patients with type 2 diabetes
Stensen, S., Gasbjerg, Lærke Smidt, Krogh, L. L., wbf943, wbf943, Skov-Jeppesen, Kirsa, Jensen, M. H., Hartmann, Bolette, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette, Christensen, M. B. & Knop, Filip Krag, 2019, In: Diabetologia. 62, Supl. 1/SI, p. S270-S271 2 p., 560.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Effects of endogenous GIP in patients with type 2 diabetes
Stensen, S., Gasbjerg, Lærke Smidt, Krogh, L. L., Skov-Jeppesen, Kirsa, wbf943, wbf943, Jensen, M. H., Dela, Flemming, Hartmann, Bolette, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette, Christensen, Mikkel Bring & Knop, Filip Krag, Apr 2021, In: European Journal of Endocrinology. 185, 1, p. 33-45Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endogenous Glucose-Dependent Insulinotropic Polypeptide Contributes to Sitagliptin-Mediated Improvement in Beta Cell Function in Patients with Type 2 Diabetes
Stensen, S., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Vilsbøll, Tina, Holst, Jens Juul, Hartmann, Bolette, Christensen, Mikkel Bring & Knop, Filip Krag, 2022, In: Diabetes. 71, 10, p. 2209-2221Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GIP and the gut-bone axis – Physiological, pathophysiological and potential therapeutic implications
Stensen, S., Gasbjerg, Lærke Smidt, Helsted, M. M., Hartmann, Bolette, Christensen, Mikkel Bring & Knop, Filip Krag, 2020, In: Peptides. 125, 7 p., 170197.Research output: Contribution to journal › Review › Research › peer-review
- Published
Acute concomitant GIP receptor antagonism during GLP-1 receptor agonism does not affect appetite, resting energy expenditure or food intake in patients with type 2 diabetes and overweight/obesity
Stensen, S., Krogh, L. L., wbf943, wbf943, Dela, Flemming, Hartmann, Bolette, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette, Christensen, Mikkel Bring, Gasbjerg, Lærke Smidt & Knop, Filip Krag, 2022, In: Diabetes, Obesity and Metabolism. 24, 9, p. 1882-1887Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Benefits and Harms of Sodium-Glucose Co-Transporter 2 Inhibitors in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis
Storgaard, H., Gluud, Lise Lotte, Bennett, C., Grøndahl, M. F., Christensen, Mikkel Bring, Knop, Filip Krag & Vilsbøll, Tina, 2016, In: PLOS ONE. 11, 11, 23 p., e0166125.Research output: Contribution to journal › Review › Research › peer-review
- Published
Glucagon-like peptide-1 receptor agonists and risk of acute pancreatitis in patients with type 2 diabetes
Storgaard, H., Cold, F., Gluud, Lise Lotte, Vilsbøll, Tina & Knop, Filip Krag, Jun 2017, In: Diabetes, Obesity and Metabolism. 19, 6, p. 906-908Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effects of sodium-glucose co-transporter 2 inhibitors in patients with type 2 diabetes: protocol for a systematic review with meta-analysis of randomised trials
Storgaard, H., Gluud, Lise Lotte, Christensen, Mikkel Bring, Knop, Filip Krag & Vilsbøll, T., 2014, In: B M J Open. 4, 8, p. 1-5 5 p., e005378.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diabetic Ketoacidosis in a Patient with Type 2 Diabetes After Initiation of Sodium-Glucose Cotransporter 2 Inhibitor Treatment
Storgaard, H., Bagger, J. I., Knop, Filip Krag, Vilsbøll, Tina & Rungby, Jørgen, Feb 2016, In: Basic & Clinical Pharmacology & Toxicology. 118, 2, p. 168-170 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A glucose-insulin-glucagon coupled model of the isoglycemic intravenous glucose infusion experiment
Subramanian, V., Bagger, J. I., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: Frontiers in Physiology. 13, 20 p., 911616.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An Extended Minimal Model of OGTT: estimation of α- and β-cell dysfunction, insulin resistance, and the incretin effect
Subramanian, V., Bagger, J. I., Harihar, V., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2024, In: American Journal of Physiology - Endocrinology and Metabolism. 326, 2, p. E182-E205Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Involvement of steatosis-induced glucagon resistance in hyperglucagonaemia
Suppli, M. P., Lund, Asger Bach, Bagger, J. I., Vilsbøll, Tina & Knop, Filip Krag, Jan 2016, In: Medical Hypotheses. 86, p. 100-3 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hepatic transcriptome signatures in patients with varying degrees of nonalcoholic fatty liver disease compared with healthy normal-weight individuals
Suppli, M. P., Rigbolt, K. T. G., Veidal, S. S., Heeboll, S., Eriksen, P. L., Demant, M., Bagger, J. I., Nielsen, J. C., Oro, D., Thrane, S. W., Lund, A., Strandberg, C., Konig, M. J., Vilsbøll, Tina, Vrang, N., Thomsen, K. L., Gronbaek, H., Jelsing, J., Hansen, H. H. & Knop, Filip Krag, 2019, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 316, 4, p. G462-G472 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon Resistance at the Level of Amino Acid Turnover in Obese Subjects With Hepatic Steatosis
Suppli, M. P., Bagger, J. I., Lund, A., Demant, M., van Hall, Gerrit, Strandberg, C., Kønig, M. J., Rigbolt, K., Langhoff, J. L., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2020, In: Diabetes. 69, 6, p. 1090-1099 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 40100368
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L-cell Differentiation Is Induced by Bile Acids Through GPBAR1 and Paracrine GLP-1 and Serotonin Signaling
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Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease
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Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production
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