Filip Krag Knop

Filip Krag Knop

Clinical Professor

Member of:

  • Internal Medicine: Endocrinology


  1. Published

    Use of antibiotics in childhood and risk of Type 1 diabetes: a population-based case-control study

    Mikkelsen, K. H., Knop, Filip Krag, Vilsbøll, Tina, Frost, M., Hallas, J. & Pottegård, A., Feb 2017, In: Diabetic Medicine. 34, 2, p. 272–277

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Influenza vaccination is associated with reduced cardiovascular mortality in adults with diabetes: A nationwide cohort study

    Modin, D., Claggett, B., Køber, Lars Valeur, Schou, Morten, Jensen , Jens-Ulrik Stæhr , Solomon, S. D., Vardeny, O., Knop, Filip Krag, Nielsen, Susanne Dam, Fralick, M., Torp-Pedersen, Christian, Gislason, Gunnar Hilmar & Biering-Sørensen, Tor, 2020, In: Diabetes Care. 43, 9, p. 2226-2233 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Dyslipidæmi ved psykisk lidelse

    Mohr, G. H., Barcella, C. A., Coello, K., Baandrup, Lone & Knop, Filip Krag, 2022, In: Ugeskrift for Laeger. 184, 10, 10 p., V05210439.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Management of people with Type 2 diabetes shared between a specialized outpatient clinic and primary health care is noninferior to management in a specialized outpatient clinic: a randomized, noninferiority trial

    Munch, L., Bennich, B. B., Overgaard, D., Konradsen, H., Middelfart, H., Kaarsberg, N., Knop, Filip Krag, Vilsbøll, Tina & Røder, M. E., 2019, In: Diabetic Medicine. 36, 7, p. 854-861

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Management of Patients with Type 2 Diabetes Shared between a Specialized Outpatient Clinic and General Practice Was Noninferior to Mono Management in a Specialized Outpatient Clinic—A Prospective, Randomized, Noninferiority Trial

    Munch, L., Bennich, B. B., Overgaard, D., Konradsen, Hanne, Middelfart, H. V., Kaarsberg, N., Knop, Filip Krag, Vilsbøll, Tina & Røder, M., 2018, In: Diabetes. 67, Supplement 1, 6-OR.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  6. Published

    Tværsektorielt samarbejde ved behandling af patienter med type 2-diabetes

    Munch, L., Røder, M. E., Rasmussen, I. H., Middelfart, H., Kaarsberg, N., Bennich, B., Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Ugeskrift for Laeger. 180, 8, p. 690-693

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Risk stratification by endocrinologists of patients with type 2 diabetes in a Danish specialised outpatient clinic: a cross-sectional study

    Munch, L., Arreskov, Anne Beiter, Sperling, M., Overgaard, D., Knop, Filip Krag, Vilsbøll, Tina & Røder, M. E., 2016, In: BMC Health Services Research. 16, 10 p., 124.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Shared care management of patients with type 2 diabetes across the primary and secondary healthcare sectors: study protocol for a randomised controlled trial

    Munch, L., Bennich, B., Arreskov, Anne Beiter, Overgaard, D., Konradsen, H., Knop, Filip Krag, Vilsbøll, Tina & Røder, M. E., 2016, In: Trials. 17, 10 p., 277.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Gastrisk aspirationsbehandling er et muligt alternativ til behandling af fedme

    Møller Christensen, M., Jorsal, T., Naver, L. P. S., Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Ugeskrift for Laeger. 179, 32, 4 p., V03170198.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The glucose-lowering effect of the bile acid sequestrant sevelamer in patients with type 2 diabetes is not mediated by glucagon-like peptide 1

    Nerild, H. H., Brønden, Andreas, Haddouchi, A. E., Holst, Jens Juul, Sonne, D. P., Vilsbøll, Tina & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 217-217 422.

    Research output: Contribution to journalConference abstract in journalResearch

  11. E-pub ahead of print

    Expression of bile acid receptors and transporters along the intestine of patients with type 2 diabetes and controls

    Nerild, H. H., Gilliam-Vigh, H., Ellegaard, A., Forman, Julie Lyng, Vilsbøll, Tina, Sonne, David Peick, Brønden, Andreas & Knop, Filip Krag, 2024, (E-pub ahead of print) In: The Journal of clinical endocrinology and metabolism.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Liraglutide changes postprandial responses of gut hormones involved in the regulation of gallbladder motility

    Nerild, H. H., Brønden, Andreas, Gether, I. M., Hellmann, P. H., Baekdal, M., Gillum, M. P., Svenningsen, J. S., Hartmann, Bolette, Rathor, N., Kudiyanur Muniraju, H. A., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina, Sonne, David Peick & Knop, Filip Krag, 2023, In: Diabetes, Obesity and Metabolism. 25, 6, p. 1632-1637

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Elucidating the glucose-lowering effect of the bile acid sequestrant sevelamer

    Nerild, H. H., Brønden, A., Haddouchi, A. E., Ellegaard, A., Hartmann, Bolette, Rehfeld, Jens Frederik, Holst, Jens Juul, Sonne, David Peick, Vilsbøll, Tina & Knop, Filip Krag, 2024, In: Diabetes, Obesity and Metabolism. 26, 4, p. 1252-1263

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Preclinical discovery and development of colesevelam for the treatment of type 2 diabetes

    Nerild, H. H., Christensen, Mikkel Bring, Knop, Filip Krag & Brønden, A., 2018, In: Expert Opinion on Drug Discovery. 13, 12, p. 1161-1167 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Effects of liraglutide on gallbladder emptying: A randomized, placebo-controlled trial in adults with overweight or obesity

    Nexoe-Larsen, C. C., Sorensen, P. H., Hausner, H., Agersnap, M., Baekdal, M., Bronden, A., Gustafsson, L. N., Sonne, David Peick, Vedtofte, L., Vilsbøll, Tina & Knop, Filip Krag, 2018, In: Diabetes, Obesity and Metabolism. 20, 11, p. 2557-2564

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Dasiglucagon Effectively Mitigates Postbariatric Postprandial Hypoglycemia: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial

    Nielsen, C. K., Øhrstrøm, C. C., Kielgast, U. L., Hansen, D. L., Hartmann, Bolette, Holst, Jens Juul, Lund, Asger Bach, Vilsbøll, Tina & Knop, Filip Krag, 2022, In: Diabetes Care. 45, 6, p. 1476–1481

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Dasiglucagon Treatment for Postprandial Hypoglycemia After Gastric Bypass: A Randomized, Double-Blind, Placebo-Controlled Trial

    Nielsen, C. K., Øhrstrøm, C. C., Houji, I. J. K., Helsted, M. M., Krogh, L. S. L., Johansen, N. J., Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: Diabetes Care. 46, 12, p. 2208-2217 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Weight loss for overweight and obese individuals with gout: a systematic review of longitudinal studies

    Nielsen, S. M., Bartels, E. M., Henriksen, Marius, Wæhrens, E. E., Gudbergsen, Henrik Rindel, Bliddal, Henning, Astrup, A., Knop, Filip Krag, Carmona, L., Taylor, W. J., Singh, J. A., Perez-Ruiz, F., Kristensen, Lars Erik Vølund & Christensen, R., 2017, In: Annals of the Rheumatic Diseases. 76, 11, p. 1870-1882 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Glucose-dependent insulinotropic polypeptide inhibits bone resorption in humans

    Nissen, A., Christensen, Mikkel Bring, Knop, Filip Krag, Vilsbøll, T., Holst, Jens Juul & Hartmann, Bolette, Nov 2014, In: The Journal of clinical endocrinology and metabolism. 99, 11, p. E2325-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease

    Niu, Lili, Geyer, P. E., Albrechtsen, Nicolai Jacob Wewer, Gluud, Lise Lotte, Santos, A., Doll, S., Treit, P. V., Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina, Junker, A., Sachs, S., Stemmer, K., Müller, T. D., Tschöp, M. H., Hofmann, S. M. & Mann, Matthias, 2019, In: Molecular Systems Biology. 15, 16 p., e8793.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Plasma proteome profiling discovers potential biomarkers of non-alcoholic fatty liver disease

    Niu, Lili, Gupta, R., Geyer, P. E., Albrechtsen, Nicolai Jacob Wewer, Gluud, Lise Lotte, Santos, A., Doll, S., Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina, Junker, A., Sachs, S., Stemmer, K., Mueller, T. D., Tschoep, M. H., Hofmann, S. M. & Mann, Matthias, Aug 2019, In: Molecular & Cellular Proteomics. 18, 8, p. S71 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  22. Published

    Recovery of the incretin effect in type 2 diabetic patients after biliopancreatic diversion

    Novaes, F. S., Vasques, A. C. J., Pareja, J. C., Knop, Filip Krag, Tura, A., Chaim, É. A. & Geloneze, B., 1 May 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 5, p. 1984-1988 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Recovery of the incretin effect in type 2 diabetic patients after biliopancreatic diversion

    Novaes, F. S., Vasques, A. C. J., Pareja, J. C., Knop, Filip Krag, Tura, A., Chaim, É. A. & Geloneze, B., 1 May 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 5, p. 1984-1988 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published
  25. Published

    The incretin effect in patients with maturity onset diabetes of the young

    Ostoft, S. H., Bagger, J. I., Hansen, T., Pedersen, O., Holst, Jens Juul, Knop, Filip Krag & Vilsboll, T., 2012, In: Diabetologia. 55, p. S144-S144

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Glucose-Lowering Effects and Low Risk of Hypoglycemia in Patients With Maturity-Onset Diabetes of the Young When Treated With a GLP-1 Receptor Agonist: A Double-Blind, Randomized, Crossover Trial

    Ostoft, S. H., Bagger, J. I., Hansen, Torben, Pedersen, Oluf Borbye, Faber, Jens, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 14 Jun 2014, In: Diabetes Care. 37, 7, p. 1797-1805 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Incretin Effect and Glucagon Responses to Oral and Intravenous Glucose in Patients with Maturity Onset Diabetes of the Young - Type 2 and Type 3

    Ostoft, S. H., Bagger, J. I., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 27 Mar 2014, In: Diabetes. 63, 8, p. 2838-44 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Recovery of gut microbiota of healthy adults following antibiotic exposure

    Palleja, A., Mikkelsen, K. H., Forslund, S. K., Kashani, A., Allin, K. H., Nielsen, T., Hansen, T. H., Liang, S., Feng, Q., Zhang, C., Pyl, P. T., Coelho, L. P., Yang, H., Wang, J., Typas, A., Nielsen, M. F., Nielsen, H. B., Bork, P., Wang, J., Vilsbøll, T. & 4 others, Hansen, Torben, Knop, Filip Krag, Arumugam, Mani & Pedersen, Oluf Borbye, Nov 2018, In: Nature Microbiology. 3, 11, p. 1255-1265 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Cardiovascular effects of high-dose glucagon: a randomised clinical trial

    Petersen, K. M., Bogevig, S., Riis, T., Andersson, N. A. W., Dalhoff, Kim, Holst, Jens Juul, Knop, Filip Krag, Faber, Jens, Petersen, Tonny Studsgaard & Christensen, Mikkel Bring, 2020, In: Diabetologia. 63, SUPPL 1, p. S231-S231

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  30. Published

    High-Dose Glucagon Has Hemodynamic Effects Regardless of Cardiac Beta-Adrenoceptor Blockade: A Randomized Clinical Trial

    Petersen, K. M., Bøgevig, S., Riis, T., Andersson, N. W., Dalhoff, Kim, Holst, Jens Juul, Knop, Filip Krag, Faber, Jens, Petersen, Tonny Studsgaard & Christensen, Mikkel Bring, 2020, In: Journal of the American Heart Association. 9, 21, 27 p., e016828.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Hemodynamic Effects of Glucagon: A Literature Review

    Petersen, K. M., Bogevig, S., Holst, Jens Juul, Knop, Filip Krag & Christensen, Mikkel Bring, 2018, In: Journal of Clinical Endocrinology & Metabolism. 103, 5, p. 1804-1812

    Research output: Contribution to journalReviewResearchpeer-review

  32. Published

    Response to Letter to the Editor: "Hemodynamic Effects of Glucagon: A Literature Review"

    Petersen, K. M., Bøgevig, S., Holst, Jens Juul, Knop, Filip Krag & Christensen, Mikkel Bring, 2018, In: The Journal of clinical endocrinology and metabolism. 103, 12, p. 4480-4481 2 p.

    Research output: Contribution to journalComment/debateResearch

  33. Published

    Characterization of oral and intravenous glucose handling in truncally vagotomised subjects with pyloroplasty

    Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Wettergren, A., Svendsen, Lars Bo, Meisner, S., Hovendal, C., Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 23 May 2013, In: European Journal of Endocrinology. 169, p. 187-201 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    The role of efferent cholinergic transmission for the insulinotropic and glucagonostatic effects of GLP-1

    Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Vilsbøll, T., Knop, Filip Krag & Holst, Jens Juul, Sep 2015, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 309, 5, p. R544-51 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    The Effect of Exogenous GLP-1 on Food Intake is Lost in Male Truncally Vagotomized Subjects with Pyloroplasty

    Plamboeck, A., Veedfald, Simon, Deacon, Carolyn F., Hartmann, Bolette, Wettergren, A., Svendsen, Lars Bo, Meisner, S., Hovendahl, C., Vilsbøll, Tina, Knop, Filip Krag & Holst, Jens Juul, 18 Apr 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 304, p. G1117-G1127 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Use of exenatide and liraglutide in Denmark: A drug utilization study

    Pottegård, A., Bjerregaard, B. K., Larsen, M. D., Larsen, K. S., Hallas, J., Knop, Filip Krag & Moreno, S. I., Feb 2014, In: European Journal of Clinical Pharmacology. 70, 2, p. 205-214 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Semaglutide for the treatment of antipsychotic-associated weight gain in patients not responding to metformin - a case series

    Prasad, F., De, R., Korann, V., Chintoh, A. F., Remington, G., Ebdrup, Bjørn, Siskind, D., Knop, Filip Krag, Vilsbøll, Tina, Fink-Jensen, Anders, Hahn, M. K. & Agarwal, S. M., 2023, In: Therapeutic Advances in Psychopharmacology. 13, 10 p., 20451253231165169.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Targeting the GLP-2 receptor in the management of obesity

    Pálsson, T. G., Gilliam-Vigh, Hannah, Jensen, Benjamin Anderschou Holbech, Jeppesen, Palle Bekker, Lund, Asger Bach, Knop, Filip Krag & Nielsen, C. K., 2024, In: Peptides. 177, 9 p., 171210.

    Research output: Contribution to journalReviewResearchpeer-review

  39. Published

    Value of gym-based group exercise versus usual care for young adults receiving antipsychotic medication: study protocol for the multicenter randomized controlled Vega trial

    Rafn, B. S., Andersen, M. F., Sørensen, V., Bjerre, E. D., Baandrup, Lone, Vernal, D. L., Mors, O., Knop, Filip Krag, Wolf, R. T., Tolver, Anders, Firth, J., Nøhr, N., Skou, S. T., Ebdrup, Bjørn & Midtgaard, Julie, 2023, In: BMC Psychiatry. 23, 1, 13 p., 634.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Systemic corticosteroids and the risk of venous thromboembolism in patients with severe copd: A nationwide study of 30, 473 outpatients

    Rastoder, E., Sivapalan, P., Eklöf, J., Saeed, M. I., Jordan, A. S., Meteran, H., Tønnesen, L., Biering-Sørensen, T., Løkke, A., Seersholm, N., Nielsen, T. L., Carlsen, J., Janner, J., Godtfredsen, N., Bodtger, U., Laursen, C. B., Hilberg, O., Knop, F. K., Priemé, H., Ingebrigtsen, T. S. & 3 others, Gottlieb, V., Wilcke, Jon Torgny Rostrup & Jensen , Jens-Ulrik Stæhr , 2021, In: Biomedicines. 9, 8, 874.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Cholecystokinin secretion is suppressed by glucagon-like peptide-1: clue to the mechanism of the adverse gallbladder events of GLP-1-derived drugs

    Rehfeld, Jens Frederik, Knop, Filip Krag, Asmar, A., Madsbad, Sten, Holst, Jens Juul & Asmar, M., 2018, In: Scandinavian Journal of Gastroenterology. 53, 12, p. 1429-1432

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Gastrin secretion in normal subjects and diabetes patients is inhibited by glucagon-like peptide 1: a role in the gastric side effects of GLP-1-derived drugs?

    Rehfeld, Jens Frederik, Knop, Filip Krag & Asmar, M., 2019, In: Scandinavian Journal of Gastroenterology. 54, 12, p. 1448-1451 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Current evidence for a role of GLP-1 in Roux-en-Y gastric bypass-induced remission of type 2 diabetes

    Rhee, N. A., Vilsbøll, Tina & Knop, Filip Krag, 2012, In: Diabetes, Obesity and Metabolism. 14, 4, p. 291-298

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Effect of Roux-en-Y gastric bypass on the distribution and hormone expression of small-intestinal enteroendocrine cells in obese patients with type 2 diabetes

    Rhee, N. A., Wahlgren, C. D., Pedersen, J., Mortensen, B., Langholz, E., Wandall, E. P., Friis, S. U., Vilmann, Peter, Paulsen, S. J., Kristiansen, V. B., Jelsing, J., Dalbøge, L. S., Poulsen, Steen Seier, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, 2015, In: Diabetologia. 58, 10, p. 2254-2258 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  45. Published

    The impact of dipeptidyl peptidase 4 inhibition on incretin effect, glucose tolerance, and gastrointestinal-mediated glucose disposal in healthy subjects

    Rhee, N. A., Østoft, S. H., Holst, Jens Juul, Deacon, Carolyn F., Vilsbøll, T. & Knop, Filip Krag, 16 Jun 2014, In: European Journal of Endocrinology. 171, 3, p. 353-362 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    The use of double-balloon enteroscopy in retrieving mucosal biopsies from the entire human gastrointestinal tract

    Rhee, N. A., Vilmann, Peter, Hassan, H., Hendel, J. W., Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, Sep 2014, In: Scandinavian Journal of Gastroenterology. 49, 9, p. 1143-1149 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    The Liver-Alpha Cell Axis in Health and in Disease

    Richter, Michael Martin, Galsgaard, Katrine Douglas, Elmelund, E., Knop, Filip Krag, Suppli, M. P., Holst, Jens Juul, Winther-Sørensen, Marie, Kjeldsen, Sasha Alexandra Sampson & Albrechtsen, Nicolai Jacob Wewer, 2022, In: Diabetes. 71, +, p. 1852–1861

    Research output: Contribution to journalReviewResearchpeer-review

  48. Published

    Clinical translatability of a diet-induced obese mouse model of non-alcoholic steatohepatitis

    Rigbolt, K., Veidal, S., Suppli, M., Eriksen, P. L., Feigh, M., Knop, Filip Krag, Gronbaek, H., Thomsen, K. L., Jelsing, J. & Vrang, N., 2019, In: Journal of Hepatology. 70, 1, p. E544 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  49. Published

    Hypothyroid women have persistently higher oxidative stress compared to healthy controls

    Riis, K. R., Larsen, C. B., Medici, B. R., Jensen, C. Z., Winther, K. H., Larsen, E. L., Ellervik, Christina, la Cour, J. L., Hegedüs, L., Brix, T. H., Poulsen, Henrik Enghusen, Knop, Filip Krag, Nygaard, Birte & Bonnema, S. J., 2023, In: European Thyroid Journal. 12, 6, 10 p., e230167.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Plasma YKL-40 during pregnancy and gestational diabetes mellitus

    Rinnov, A. R., Rathcke, C. N., Bonde, L., Vilsbøll, Tina & Knop, Filip Krag, 2015, In: Journal of Reproductive Immunology. 112, p. 68-72

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Increased glucagon sensitivity in totally pancreatectomised patients

    Rix, I., Lund, A., Garvey, Lene Heise, Owen, K., Hansen, C., van Hall, Gerrit, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 118-119 226.

    Research output: Contribution to journalConference abstract in journalResearch

  52. Published

    Hyperglucagonaemia and amino acid alterations in individuals with type 2 diabetes and non-alcoholic fatty liver disease

    Rix, I., Johansen, M. L., Lund, A., Suppli, M. P., Chabanova, E., van Hall, Gerrit, Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Kistorp, Caroline Michaela Nervil & Knop, Filip Krag, 2023, In: Endocrine Connections. 13, 1, 11 p., e230161.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Effect of the EndoBarrier Gastrointestinal Liner on obesity and type 2 diabetes: a systematic review and meta-analysis

    Rohde, U., Hedbäck, N., Gluud, Lise Lotte, Vilsbøll, Tina & Knop, Filip Krag, Mar 2016, In: Diabetes, Obesity and Metabolism. 18, 3, p. 300-5 6 p.

    Research output: Contribution to journalLetterResearchpeer-review

  54. Published

    Premature explantation of an EndoBarrier gastrointestinal liner because of sleeve invagination

    Rohde, U., Federspiel, C. A., Vilmann, Peter, Friis, S. U., Langholz, E., Vilsbøll, Tina & Knop, Filip Krag, 2015, In: Endoscopy. 47 , Suppl 1 , p. E275-6 2 p.

    Research output: Contribution to journalLetterResearchpeer-review

  55. Published

    The impact of EndoBarrier gastrointestinal liner in obese patients with normal glucose tolerance and in patients with type 2 diabetes

    Rohde, U., Federspiel, C. A., Vilmann, Peter, Langholz, Ebbe, Friis, S. U., Krakauer, M., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Feb 2017, In: Diabetes, Obesity and Metabolism. 19, 2, p. 189-199 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Effect of the EndoBarrier Gastrointestinal Liner on obesity and type 2 diabetes: protocol for systematic review and meta-analysis of clinical studies

    Rohde, U., Hedbäck, N., Gluud, Lise Lotte, Vilsbøll, T. & Knop, Filip Krag, 2013, In: B M J Open. 3, 9, p. 1-5 e003417.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Cholecystokinin-Induced Gallbladder Emptying and Single-Dose Metformin Elicit Additive Glucagon-Like Peptide-1 Responses

    Rohde, U., Sonne, D. P., Christensen, M., Hansen, M., Brønden, A., Toräng, S., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 1 May 2016, In: The Journal of clinical endocrinology and metabolism. 101, 5, p. 2076-2083

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Behandling med duodenal-jejunal bypass-sleeve ved svær overvægt

    Rohde, U., Gylvin, S., Vilmann, Peter, Friis, S. U., Langholz, Ebbe, Vilsbøll, T. & Knop, Filip Krag, 29 Sep 2014, In: Ugeskrift for Laeger. 176, 37, p. 1874-1877 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Diagnostik og behandling af maturity onset diabetes of the young type 3

    Rose, K., Christensen, A. S., Storgaard, H., Hædersdal, S., Hansen, Torben, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Ugeskrift for Laeger. 180, 6 p., V06170502.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Greater time spent with HbA1c less than 7.0% with oral semaglutide versus oral comparators: An exploratory analysis of the PIONEER studies

    Rosenstock, J., Cariou, B., Eliasson, J., Frappin, G., Kaltoft, M. S., Montanya, E. & Knop, Filip Krag, 2024, In: Diabetes, Obesity and Metabolism. 26, 2, p. 532-539 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Sodium-glucose cotransporter 2 (SGLT-2) inhibitors for patients with Type 2 diabetes

    Røder, M. E., Storgaard, H., Rungby, Jørgen, Knop, Filip Krag & Vilsbøll, Tina, 19 Sep 2016, In: Ugeskrift for Laeger. 178, 38

    Research output: Contribution to journalReviewResearchpeer-review

  62. Published

    Sodium-glucose cotransporter (SGLT)-2-inhibitorer til patienter med type 2-diabetes

    Røder, M. E., Storgaard, H., Rungby, J., Knop, Filip Krag & Vilsbøll, Tina, 26 Dec 2016, In: Ugeskrift for Laeger. 178, 26, p. 2461-64 V05160310.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Sodium-glucose cotransporter 2 (SGLT-2) inhibitors for patients with Type 2 diabetes

    Røder, M. E., Storgaard, H., Rungby, Jørgen, Knop, Filip Krag & Vilsbøll, Tina, 19 Sep 2016, In: Ugeskrift for Laeger. 178, 38

    Research output: Contribution to journalReviewResearchpeer-review

  64. Published

    Mathematical Modelling of Glucose-Dependent Insulinotropic Polypeptide and Glucagon-like Peptide-1 following Ingestion of Glucose

    Røge, R. M., Bagger, J. I., Alskär, O., Kristensen, N. R., Klim, S., Holst, Jens Juul, Ingwersen, S. H., Karlsson, M. O., Knop, Filip Krag, Vilsbøll, Tina & Kjellsson, M. C., Oct 2017, In: Basic & Clinical Pharmacology & Toxicology. 121, 4, p. 290-297 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Use of inhaled corticosteroids and the risk of developing type 2 diabetes in patients with chronic obstructive pulmonary disease

    Saeed, M. I., Eklof, J., Achir, I., Sivapalan, P., Meteran, Howraman, Lokke, A., Biering-Sørensen, Tor, Knop, Filip Krag & Jensen , Jens-Ulrik Stæhr , 2020, In: Diabetes, Obesity and Metabolism. 22, 8, p. 1348-1356 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Secretion of parathyroid hormone may be coupled to insulin secretion in humans

    Sass, M. R., Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Hare, Kristine Juul, Borbye-Lorenzen, N., Kiss, K., Vilsbøll, Tina, Knop, Filip Krag, Poulsen, Steen Seier, Jørgensen, Niklas Rye, Holst, Jens Juul, Ørskov, Cathrine & Hartmann, Bolette, 2020, In: Endocrine Connections. 9, 7, p. 747-754

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published
  68. Published

    The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells

    Schisler, J. C., Jensen, P. B., Harper, D. A. T., Becker, T., Knop, Filip Krag, Takekawa, S., German, M., Weir, G. C., Lu, D., Mirmira, R. G. & Newgard, C. B., 17 May 2005, In: Proceedings of the National Academy of Sciences of the United States of America. 102, 20, p. 7297-302 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Effects of sitagliptin on counterregulatory and incretin hormones during acute hypoglycaemia in patients with type 1 diabetes: a randomized double blind placebo-controlled cross-over study

    Schopman, J. E., Hoekstra, J. B. L., Frier, B. M., Ackermans, M. T., de Sonnaville, J. J. J., Stades, A. M., Zwertbroek, R., Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag & Holleman, F., Jun 2015, In: Diabetes, Obesity and Metabolism. 17, 6, p. 546-53 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Future Perspectives on GLP-1 Receptor Agonists and GLP-1/glucagon Receptor Co-agonists in the Treatment of NAFLD

    Seghieri, M., Christensen, A. S., Andersen, A., Solini, A., Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Frontiers in Endocrinology. 9, p. 1-10 649.

    Research output: Contribution to journalReviewResearchpeer-review

  71. Published

    Glucagon-like peptide-1 receptor agonists for antipsychotic-associated cardio-metabolic risk factors: a systematic review and individual participant data meta-analysis

    Siskind, D., Hahn, M., Correll, C. U., Fink-Jensen, Anders, Russell, A. W., Bak, N., Broberg, B. V., Larsen, J., Ishoy, P. L., Vilsbøll, Tina, Knop, Filip Krag, Kisely, S. & Ebdrup, Bjørn, 2019, In: Diabetes, Obesity and Metabolism. 21, 2, p. 293-302 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  72. Published

    Azithromycin and hydroxychloroquine in hospitalised patients with confirmed COVID-19: a randomised double-blinded placebo-controlled trial

    Sivapalan, P. & ProPAC-COVID writing group on behalf of the ProPAC-COVID Study Group, P. W. G. O. B. O. T. P. S. G., 2022, In: European Respiratory Journal. 59, 1, 2100752.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Proactive prophylaxis with azithromycin and hydroxychloroquine in hospitalized patients with COVID-19 (ProPAC-COVID): a statistical analysis plan

    Sivapalan, P., Ulrik, Charlotte Suppli, Lappere, T. S., Eklöf, J. V., Shaker, Saher Burhan, Bødtger, U. C. S., Browatzki, A., Meyer, Christian, Weinreich, U. M., Laursen, C. B., Biering-Sørensen, Tor, Knop, Filip Krag, Lundgren, Jens & Jensen , Jens-Ulrik Stæhr , 2020, In: Trials. 21, 1, 867.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Proactive Prophylaxis With Azithromycin and HydroxyChloroquine in Hospitalised Patients With COVID-19 (ProPAC-COVID): A structured summary of a study protocol for a randomised controlled trial

    Sivapalan, P., Ulrik, C. S., Bojesen, R. D., Lapperre, T. S., Eklöf, J. V., Håkansson, K. E. J., Browatzki, A., Tidemansen, C., Wilcke, J. T., Janner, J., Gottlieb, V., Meteran, H., Porsbjerg, C., Madsen, B. L., Moberg, M., Pedersen, L., Benfield, T. L., Lundgren, J. D., Knop, F. K., Biering-Sørensen, T. & 13 others, Ghanizada, M., Sonne, T. P., Bødtger, U. C. S., Jensen, S. G., Rasmussen, D. B., Brøndum, E., Tupper, O. D., Sørensen, S. W., Alstrup, G., Laursen, C. B., Møller, U. W., Sverrild, A. & Jensen , Jens-Ulrik Stæhr , 2020, In: Trials. 21, 4 p., 513.

    Research output: Contribution to journalLetterResearchpeer-review

  75. Published

    Myocardial Impairment and Acute Respiratory Distress Syndrome in Hospitalized Patients With COVID-19: The ECHOVID-19 Study

    Skaarup, K. G., Lassen, M. C. H., Lind, J. N., Alhakak, A. S., Sengeløv, M., Nielsen, A. B., Espersen, C., Hauser, R., Schöps, L. B., Holt, E., Johansen, N. D., Modin, D., Sharma, S., Graff, C., Bundgaard, H., Hassager, C., Jabbari, R., Lebech, A. M., Kirk, O., Bødtger, U. & 22 others, Lindholm, M. G., Joseph, G., Wiese, L., Schiødt, Frank Vinholt, Kristiansen, O. P., Walsted, E. S., Nielsen, Olav Wendelboe, Lindegaard, Birgitte, Tønder, N., Benfield, Thomas, Jeschke, K. N., Ulrik, Charlotte Suppli, Knop, Filip Krag, Pallisgaard, J., Lamberts, Morten Kjøbek, Sivapalan, P., Gislason, Gunnar Hilmar, Solomon, S. D., Iversen, Kasper, Jensen, J. U. S., Schou, Morten & Biering-Sørensen, Tor, 2020, In: JACC: Cardiovascular Imaging. 13, 11, p. 2474-2476 3 p.

    Research output: Contribution to journalLetterResearchpeer-review

  76. Published

    Diabetes and obesity treatment based on dual incretin receptor activation: ‘twincretins’

    Skow, M. A., Bergmann, N. C. & Knop, Filip Krag, Sep 2016, In: Diabetes, Obesity and Metabolism. 18, 9, p. 847-54 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  77. Published

    Comment on Xu et al. Effects of Metformin on Metabolite Profiles and LDL Cholesterol in Patients With Type 2 Diabetes

    Sonne, David Peick & Knop, Filip Krag, Dec 2015, In: Diabetes Care. 38, 12, p. e215 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  78. Published

    On the role of gallbladder emptying and incretin hormones for nutrient-mediated TSH suppression in patients with type 2 diabetes

    Sonne, David Peick, Lund, Asger Bach, Faber, J., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Dec 2014, In: Endocrine Connections. 3, 4, p. 193-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Postprandial Plasma Concentrations of Individual Bile Acids and FGF-19 in Patients With Type 2 Diabetes

    Sonne, David Peick, van Nierop, F. S., Kulik, W., Soeters, M. R., Vilsbøll, Tina & Knop, Filip Krag, Aug 2016, In: Endocrinology. 101, 8, p. 3002-3009 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Pancreatic Amylase and Lipase Plasma Concentrations Are Unaffected by Increments in Endogenous GLP-1 Levels Following Liquid Meal Tests

    Sonne, David Peick, Vilsbøll, T. & Knop, Filip Krag, 2015, In: Diabetes Care. 38, 5, p. e71-2 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Postprandial gut hormone responses and glucose metabolism in cholecystectomized patients

    Sonne, D. P., Hare, K. J., Martens, P., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 15 Feb 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 304, 4, p. G413-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Postprandial gallbladder emptying in patients with type 2 diabetes: potential implications for bile-induced secretion of glucagon-like peptide 1

    Sonne, David Peick, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Oct 2014, In: European Journal of Endocrinology. 171, 4, p. 407-419 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Postprandial Plasma Concentrations of ProANP in Patients with Type 2 Diabetes and Healthy Controls

    Sonne, D. P., Terzic, D., Knop, Filip Krag & Goetze, Jens P. , May 2017, In: Clinical Chemistry. 63, 5, p. 1040-1041 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  84. Published

    Species-specific action of (Pro3)GIP - an efficacious agonist on human GIP receptor, but partial agonist and competitive antagonist on rat and mouse GIP receptors

    wbf943, wbf943, Gasbjerg, Lærke Smidt, Svendsen, B., Christensen, M., Knop, Filip Krag, Hartmann, Bolette, Holst, Jens Juul & Rosenkilde, Mette, Jan 2016, In: British Journal of Pharmacology. 173, 1, p. 27-38 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Vagotomy and subsequent development of diabetes: A nested case-control study

    Starup-Linde, J., Gejl, M., Borghammer, P., Knop, Filip Krag, Gregersen, S., Rungby, Jørgen & Vestergaard, P., Jul 2016, In: Metabolism. 65, 7, p. 954-960 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Glucose-dependent insulinotropic polypeptide (GIP) contributes to sitagliptin-mediated improvement of beta cell function in patients with type 2 diabetes

    Stensen, S., Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Hartmann, Bolette, Vilsbøll, Tina, Holst, Jens Juul, Christensen, M. B. & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 95-95 179.

    Research output: Contribution to journalConference abstract in journalResearch

  87. Published

    Endogenous glucose-dependent insulinotropic polypeptide exerts diverging and tissue specific in obese patients with type 2 diabetes

    Stensen, S., Gasbjerg, Lærke Smidt, Krogh, L. L., wbf943, wbf943, Skov-Jeppesen, Kirsa, Jensen, M. H., Hartmann, Bolette, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette, Christensen, M. B. & Knop, Filip Krag, 2019, In: Diabetologia. 62, Supl. 1/SI, p. S270-S271 2 p., 560.

    Research output: Contribution to journalConference abstract in journalResearch

  88. Published

    Effects of endogenous GIP in patients with type 2 diabetes

    Stensen, S., Gasbjerg, Lærke Smidt, Krogh, L. L., Skov-Jeppesen, Kirsa, wbf943, wbf943, Jensen, M. H., Dela, Flemming, Hartmann, Bolette, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette, Christensen, Mikkel Bring & Knop, Filip Krag, Apr 2021, In: European Journal of Endocrinology. 185, 1, p. 33-45

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published
  90. Published

    GIP and the gut-bone axis – Physiological, pathophysiological and potential therapeutic implications

    Stensen, S., Gasbjerg, Lærke Smidt, Helsted, M. M., Hartmann, Bolette, Christensen, Mikkel Bring & Knop, Filip Krag, 2020, In: Peptides. 125, 7 p., 170197.

    Research output: Contribution to journalReviewResearchpeer-review

  91. Published
  92. Published

    Benefits and Harms of Sodium-Glucose Co-Transporter 2 Inhibitors in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis

    Storgaard, H., Gluud, Lise Lotte, Bennett, C., Grøndahl, M. F., Christensen, Mikkel Bring, Knop, Filip Krag & Vilsbøll, Tina, 2016, In: PLOS ONE. 11, 11, 23 p., e0166125.

    Research output: Contribution to journalReviewResearchpeer-review

  93. Published

    Glucagon-like peptide-1 receptor agonists and risk of acute pancreatitis in patients with type 2 diabetes

    Storgaard, H., Cold, F., Gluud, Lise Lotte, Vilsbøll, Tina & Knop, Filip Krag, Jun 2017, In: Diabetes, Obesity and Metabolism. 19, 6, p. 906-908

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    The effects of sodium-glucose co-transporter 2 inhibitors in patients with type 2 diabetes: protocol for a systematic review with meta-analysis of randomised trials

    Storgaard, H., Gluud, Lise Lotte, Christensen, Mikkel Bring, Knop, Filip Krag & Vilsbøll, T., 2014, In: B M J Open. 4, 8, p. 1-5 5 p., e005378.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Diabetic Ketoacidosis in a Patient with Type 2 Diabetes After Initiation of Sodium-Glucose Cotransporter 2 Inhibitor Treatment

    Storgaard, H., Bagger, J. I., Knop, Filip Krag, Vilsbøll, Tina & Rungby, Jørgen, Feb 2016, In: Basic & Clinical Pharmacology & Toxicology. 118, 2, p. 168-170 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    A glucose-insulin-glucagon coupled model of the isoglycemic intravenous glucose infusion experiment

    Subramanian, V., Bagger, J. I., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: Frontiers in Physiology. 13, 20 p., 911616.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    An Extended Minimal Model of OGTT: estimation of α- and β-cell dysfunction, insulin resistance, and the incretin effect

    Subramanian, V., Bagger, J. I., Harihar, V., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2024, In: American Journal of Physiology - Endocrinology and Metabolism. 326, 2, p. E182-E205

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Involvement of steatosis-induced glucagon resistance in hyperglucagonaemia

    Suppli, M. P., Lund, Asger Bach, Bagger, J. I., Vilsbøll, Tina & Knop, Filip Krag, Jan 2016, In: Medical Hypotheses. 86, p. 100-3 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Hepatic transcriptome signatures in patients with varying degrees of nonalcoholic fatty liver disease compared with healthy normal-weight individuals

    Suppli, M. P., Rigbolt, K. T. G., Veidal, S. S., Heeboll, S., Eriksen, P. L., Demant, M., Bagger, J. I., Nielsen, J. C., Oro, D., Thrane, S. W., Lund, A., Strandberg, C., Konig, M. J., Vilsbøll, Tina, Vrang, N., Thomsen, K. L., Gronbaek, H., Jelsing, J., Hansen, H. H. & Knop, Filip Krag, 2019, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 316, 4, p. G462-G472 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Glucagon Resistance at the Level of Amino Acid Turnover in Obese Subjects With Hepatic Steatosis

    Suppli, M. P., Bagger, J. I., Lund, A., Demant, M., van Hall, Gerrit, Strandberg, C., Kønig, M. J., Rigbolt, K., Langhoff, J. L., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2020, In: Diabetes. 69, 6, p. 1090-1099 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 40100368