Flemming Pociot

Flemming Pociot

Clinical Professor

Member of:

  • Internal Medicine: Endocrinology


  1. 2003
  2. Published

    Association of a functional 17beta-estradiol sensitive IL6-174G/C promoter polymorphism with early-onset type 1 diabetes in females

    Kristiansen, O. P., Nolsøe, R. L., Larsen, L., Gjesing, A. M. P., Johannesen, J., Larsen, Z. M. E., Lykkesfeldt, A. E., Karlsen, A. E., Pociot, Flemming, Mandrup-Poulsen, Thomas & DIEGG, D., 15 May 2003, In: Human Molecular Genetics. 12, 10, p. 1101-10 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2004
  4. Published

    Type 1 database mellitus: an inflammatory disease of the islet.

    Bergholdt, R., Heding, P., Nielsen, K., Nolsøe, R., Sparre, T., Størling, J., Nerup, J., Pociot, Flemming & Mandrup-Poulsen, Thomas, 2004, In: Advances in Experimental Medicine and Biology. 552, p. 129-53 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Identification of a type 1 diabetes-associated CD4 promoter haplotype with high constitutive activity

    Kristiansen, O. P., Karlsen, A. E., Larsen, Z. M., Johannesen, Jesper, Pociot, Flemming, Mandrup-Poulsen, Thomas & Danish IDDM Epidemiology and Genetics Group and Danish Study Group of IDDM in Childhood, D. I. E. A. G. G. A. D. S. G. O. I. I. C., 1 Jun 2004, In: Scandinavian Journal of Immunology. 59, 6, p. 582-91 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Mutation analysis of suppressor of cytokine signalling 3, a candidate gene in Type 1 diabetes and insulin sensitivity

    Gylvin, T., Nolsøe, R., Hansen, Torben, Nielsen, E. M. D., Bergholdt, R., Karlsen, A. E., Billestrup, Nils, Borch-Johnsen, K., Pedersen, O., Mandrup-Poulsen, Thomas, Nerup, J. & Pociot, Flemming, 1 Jul 2004, In: Diabetologia. 47, 7, p. 1273-7 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Suppressor of cytokine signalling (SOCS)-3 protects beta cells against IL-1beta-mediated toxicity through inhibition of multiple nuclear factor-kappaB-regulated proapoptotic pathways

    Karlsen, A. E., Heding, P. E., Frobøse, H., Rønn, S. G., Kruhøffer, M., Orntoft, T. F., Darville, M., Eizirik, D. L., Pociot, Flemming, Nerup, J., Mandrup-Poulsen, Thomas & Billestrup, Nils, 1 Nov 2004, In: Diabetologia. 47, 11, p. 1998-2011 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2005
  9. Published

    Functional promoter haplotypes of the human FAS gene are associated with the phenotype of SLE characterized by thrombocytopenia

    Nolsøe, R. L., Kelly, J. A., Pociot, Flemming, Moser, K., Kristiansen, O. P., Mandrup-Poulsen, Thomas & Harley, J. B., 1 Dec 2005, In: Genes and Immunity. 6, 8, p. 699-706 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2007
  11. Published

    A human phenome-interactome network of protein complexes implicated in genetic disorders

    Lage, K., Karlberg, E. O., Størling, Z. M., Olason, P. I., Pedersen, A. G., Rigina, O., Hinsby, A. M., Tümer, Asuman Zeynep, Pociot, Flemming, Tommerup, Niels, Moreau, Y. & Brunak, S., 2007, In: Nature Biotechnology. 25, 3, p. 309-16 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Integrative analysis for finding genes and networks involved in diabetes and other complex diseases

    Bergholdt, R., Størling, Z. M., Lage, K., Karlberg, E. O., Olason, P. I., Aalund, M., Nerup, J., Brunak, Søren, Workman, C. & Pociot, Flemming, 2007, In: Genome Biology (Online Edition). 8, 11, p. R253

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Transcriptional profiling of type 1 diabetes genes on chromosome 21 in a rat beta-cell line and human pancreatic islets

    Bergholdt, R., Karlsen, A. E., Hagedorn, P. H., Aalund, M., Nielsen, Jens Høiriis, Kruhoffer, M., Orntoft, T., Wang, H., Wollheim, C. B., Nerup, J. & Pociot, Flemming, 2007, In: Genes and Immunity. 8, 3, p. 232-238 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Ætiologi og patogenese, Type 1

    Bergholdt, R., Larsen, C. M., Pociot, Flemming, Mandrup-Poulsen, Thomas, Hilsted, J. C., Christensen, J. S. & Borch-Johnsen, K., 2007, Diabetes. 1 ed. København: Handelshøjskolens Forlag, Vol. 6. p. -

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  15. 2008
  16. Published

    A human type 1 diabetes susceptibility locus maps to chromosome 21q22.3

    Concannon, P., Onengut-Gumuscu, S., Todd, J. A., Smyth, D. J., Pociot, Flemming, Bergholdt, R., Akolkar, B., Erlich, H. A., Hilner, J. E., Julier, C., Morahan, G., Nerup, J., Nierras, C. R., Chen, W. M. & Rich, S. S., 2008, In: Diabetes. 57, 10, p. 2858-2861 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    A non-synonymous variant in SLC30A8 is not associated with type 1 diabetes in the Danish population

    Brorsson, C., Bergholdt, R., Sjogren, M., Eising, S., Sorensen, K. M., Hougaard, D. M., Orho-Melander, M., Groop, L. & Pociot, Flemming, 2008, In: Molecular Genetics and Metabolism. 94, 3, p. 386-388 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Mass spectrometry is only one piece of the puzzle in clinical proteomics

    McGuire, J. N., Overgaard, J. & Pociot, Flemming, 2008, In: Briefings in Functional Genomics and Proteomics. 7, 1, p. 74-83 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The Faroese, a genetic isolate with a strong founder effect, allows the identification of Type 1 diabetes susceptibility regions

    Nolsoe, R., Roin, J., Deckert, M., Bergholdt, R., Kelly, J., Brorsson, C., Harley, J., Olsen, S., Pociot, Flemming & Mandrup-Poulsen, Thomas, 2008, In: Clinical Immunology. 127, Suppl. S, p. S105-S105

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Variation within the PPARG gene is associated with residual beta-cell function and glycemic control in children and adolescents during the first year of clinical type 1 diabetes

    Porksen, S., Nielsen, L. B., Mortensen, H. B., Danne, T., Kocova, M., Castano, L., Pociot, Flemming, Hougaard, P., Ekstrom, C. T., Gammeltoft, S., Knip, M. & Hansen, L., 2008, In: Pediatric Diabetes Online. 9, 4, p. 297-302 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2009
  22. Published

    Expression profiling of human genetic and protein interaction networks in type 1 diabetes

    Bergholdt, R., Brorsson, C., Lage, K., Nielsen, Jens Høiriis, Brunak, S. & Pociot, Flemming, 2009, In: PLoS ONE. 4, 7, p. e6250

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Functional SOCS1 polymorphisms are associated with variation in obesity in whites

    Gylvin, T., Ek, J., Nolsøe, R., Albrechtsen, A., Andersen, G., Bergholdt, R., Brorsson, C., Bang-Berthelsen, C. H., Hansen, T., Karlsen, A. E., Billestrup, N., Borch-Johnsen, K., Jørgensen, T., Pedersen, Oluf Borbye, Mandrup-Poulsen, Thomas, Nerup, J. & Pociot, Flemming, 2009, In: Diabetes, Obesity and Metabolism. 11, 3, p. 196-203 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

    Barrett, J. C., Clayton, D. G., Concannon, P., Akolkar, B., Cooper, J. D., Erlich, H. A., Julier, C., Morahan, G., Nerup, J., Nierras, C., Plagnol, V., Pociot, Flemming, Schuilenburg, H., Smyth, D. J., Stevens, H., Todd, J. A., Walker, N. M., Rich, S. S. & The Type 1 Diabetes Genetics Consortium, T. T. 1. D. G. C., 2009, In: Nature Genetics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Genome-wide scan for linkage to type 1 diabetes in 2,496 multiplex families from the type 1 diabetes genetics consortium

    Concannon, P., Chen, W. M., Julier, C., Morahan, G., Akolkar, B., Erlich, H. A., Hilner, J. E., Nerup, J., Nierras, C., Pociot, Flemming, Todd, J. A. & Rich, S. S., 2009, In: Diabetes. 58, 4, p. 1018-1022 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    No association of the IRS1 and PAX4 genes with type I diabetes

    Bergholdt, R., Brorsson, C., Boehm, B., Morahan, G. & Pociot, Flemming, 2009, In: Genes and Immunity. 10, p. S49-S53 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Reproducible association with type 1 diabetes in the extended class I region of the major histocompatibility complex

    Viken, M. K., Blomhoff, A., Olsson, M., Akselsen, H. E., Pociot, Flemming, Nerup, J., Kockum, I., Cambon-Thomsen, A., Thorsby, E., Undlien, D. E. & Lie, B. A., 2009, In: Genes and Immunity. 10, 4, p. 323-333 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Results of the MHC fine mapping workshop

    Rich, S. S., Akolkar, B., Concannon, P., Erlich, H., Hilner, J., Julier, C., Morahan, G., Nerup, J., Nierras, C., Pociot, Flemming & Todd, J. A., 2009, In: Diabetes, Obesity and Metabolism. 11, SUPPL. 1, p. 108-109 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Zinc transporter gene expression is regulated by pro-inflammatory cytokines: A potential role for zinc transporters in beta-cell apoptosis?

    Egefjord, L., Jensen, J. L., Bang-Berthelsen, C. H., Petersen, A. B., Smidt, K., Schmitz, O., Karlsen, A. E., Pociot, Flemming, Chimienti, F., Rungby, J. & Magnusson, N. E., 2009, In: BMC Endocrine Disorders. 9

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Identification of T1D susceptibility genes within the MHC region by combining protein interaction networks and SNP genotyping data

    Brorsson, C., Hansen, N. T., Lage, K., Bergholdt, R., Brunak, Søren, Pociot, Flemming & Diabetes Genetics Consortium, D. G. C., Feb 2009, In: Diabetes, Obesity and Metabolism Online. 11, SUPPL. 1, p. 60-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. 2010
  32. Published

    Plasma proteome analysis of patients with type 1 diabetes with diabetic nephropathy

    Overgaard, A. J., Hansen, H. G., Lajer, M., Pedersen, L., Tarnow, L., Rossing, Peter, McGuire, J. N. & Pociot, Flemming, 2010, In: Proteome Science. 8, p. 4 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 922065