Mutation analysis of suppressor of cytokine signalling 3, a candidate gene in Type 1 diabetes and insulin sensitivity
Research output: Contribution to journal › Journal article › Research › peer-review
Beta cell loss in Type 1 and Type 2 diabetes mellitus may result from apoptosis and necrosis induced by inflammatory mediators. The suppressor of cytokine signalling (SOCS)-3 is a natural inhibitor of cytokine signalling and also influences insulin signalling. SOCS3 could therefore be a candidate gene in the development of Type 1 and Type 2 diabetes mellitus.
| Original language | English |
|---|---|
| Journal | Diabetologia |
| Volume | 47 |
| Issue number | 7 |
| Pages (from-to) | 1273-7 |
| Number of pages | 5 |
| ISSN | 0012-186X |
| DOIs | |
| Publication status | Published - 1 Jul 2004 |
- Adolescent, Adult, Base Sequence, Child, Child, Preschool, DNA Mutational Analysis, DNA Primers, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Family, Humans, Infant, Insulin, Polymerase Chain Reaction, Polymorphism, Single Nucleotide, Repressor Proteins, Signal Transduction, Suppressor of Cytokine Signaling Proteins, Transcription Factors
Research areas
ID: 33902590