Sten Madsbad
Clinical Professor
Department of Clinical Medicine
Kettegård Allé 30, 2650 Hvidovre
Member of:
Internal Medicine: Endocrinology
- 2020
- Published
No effects of a 6-week intervention with a glucagon-like peptide-1 receptor agonist on pancreatic volume and oedema in obese men without diabetes
Svane, M. S., Johannesen, Helle Hjorth, Martinussen, C., Bojsen-Moller, K. N., Hansen, M. L., Hansen, Adam Espe, Deacon, Carolyn F., Hartmann, Bolette, Keller, S. H., Klausen, T. L., Loft, A., Kjær, Andreas, Madsbad, Sten, Lofgren, J., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Diabetes, Obesity and Metabolism. 22, 10, p. 1837-1846Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nonalcoholic Fatty Liver Disease Impairs the Liver-Alpha Cell Axis Independent of Hepatic Inflammation and Fibrosis
Pedersen, J. S., Rygg, M. O., Kristiansen, V. B., Olsen, B. H., Serizawa, R. R., Holst, Jens Juul, Madsbad, Sten, Gluud, Lise Lotte, Bendtsen, Flemming & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Hepatology Communications. 4, 11, p. 1610-1623 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced carbohydrate and increased protein and fat in the diet augment the positive effect of weight loss on glucose control in type 2 diabetes patients
Thomsen, M. N., Skytte, M. J., Samkani, A., Carl, M. H., Weber, P., Astrup, A., Larsen, T. M., Frystyk, J., Holst, Jens Juul, Hartmann, Bolette, Thomsen, Henrik S., Chabanova, E., Madsbad, Sten, Haugaard, Steen Bendix & Krarup, T., 2020, In: Diabetologia. 63, Suppl. 1, p. S295-S296 614.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Reduction of oxidative stress on DNA and RNA in obese patients after Roux-en-Y gastric bypass surgery-An observational cohort study of changes in urinary markers
Carlsson, E. R., Fenger, M., Henriksen, T., Kjaer, L. K., Worm, Dorte, Hansen, D. L., Madsbad, Sten & Poulsen, Henrik Enghusen, 2020, In: PLoS ONE. 15, 12 December, e0243918.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Responses of gut and pancreatic hormones, bile acids, and fibroblast growth factor-21 differ to glucose, protein, and fat ingestion after gastric bypass surgery
Jensen, C. Z., Bojsen-Møller, K. N., Svane, M. S., Holst, L. M., Hermansen, K., Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Kristiansen, V. B., Rehfeld, Jens Frederik, Clausen, T. R., Holst, Jens Juul & Madsbad, Sten, 2020, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 318, 4, p. G661-G672 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretin release after Roux-en-Y gastric bypass reveals a population of glucose-sensitive S cells in distal small intestine
Modvig, Ida Marie, Andersen, Daniel Bjørklund, Grunddal, Kaare Villum, Kuhre, Rune Ehrenreich, Martinussen, C., Christiansen, Charlotte Bayer, Ørskov, Cathrine, Larraufie, P., Kay, R. G., Reimann, F., Gribble, F. M., Hartmann, Bolette, Bojsen-Moller, K. N., Madsbad, Sten, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2020, In: International Journal of Obesity. 44, 9, p. 1859-1871Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The clinical effects of a carbohydrate-reduced high-protein diet on glycaemic variability in metformin-treated patients with type 2 diabetes mellitus: A randomised controlled study
Thomsen, M. N., fbg982, fbg982, Astrup, A., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten, Krarup, T., Haugaard, Steen Bendix & Samkani, A., 2020, In: Clinical Nutrition ESPEN. 39, p. 46-52 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of acute dual SGLT1/SGLT2 inhibition on incretin release and glucose metabolism after gastric bypass surgery
Martinussen, C., Veedfald, Simon, Dirksen, Carsten Moro, Bojsen-Møller, K. N., Svane, M. S., Albrechtsen, Nicolai Jacob Wewer, van Hall, Gerrit, Kristiansen, V. B., Fenger, M., Holst, Jens Juul & Madsbad, Sten, 2020, In: American Journal of Physiology: Endocrinology and Metabolism. 318, 6, p. E956-E964 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Weight loss-induced improvements of endothelial function and cardiovascular risk factors are maintained with exercise, liraglutide or the combination
Lundgren, J. R., Bladbjerg, E. M., Janus, C., Gliemann, Lasse, Olsen, L. M., Juhl, C. R., Jensen, Simon Birk Kjær, Thirumathyam, R., Stallknecht, Bente Merete, Holst, Jens Juul, Hove, Jens Dahlgaard, Madsbad, Sten, Antoinades, C. & Torekov, Signe Sørensen, 2020, In: Diabetologia. 63, SUPPL 1, p. S457-S457 1 p., 959.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- 2019
- Published
Liraglutide in combination with metformin may improve the atherogenic lipid profile and decrease C-reactive protein level in statin treated obese patients with coronary artery disease and newly diagnosed type 2 diabetes: A randomized trial
Anholm, C., Kumarathurai, P., Pedersen, L. R., Samkani, A., Walzem, R. L., Nielsen, Olav Wendelboe, Kristiansen, O. P., Fenger, M., Madsbad, Sten, Sajadieh, Ahmad & Haugaard, Steen Bendix, Sep 2019, In: Atherosclerosis. 288, p. 60-66 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Augmented GLP-1 Secretion as Seen After Gastric Bypass May Be Obtained by Delaying Carbohydrate Digestion
Martinussen, C., Bojsen-Møller, K. N., Dirksen, C., Svane, M. S., Kristiansen, V. B., Hartmann, Bolette, Holst, Jens Juul & Madsbad, Sten, Aug 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 8, p. 3233–3244Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficacy and safety of oral semaglutide in patients with type 2 diabetes and moderate renal impairment (PIONEER 5): a placebo-controlled, randomised, phase 3a trial
Mosenzon, O., Blicher, T. M., Rosenlund, S., Eriksson, J. W., Heller, S., Hels, O. H., Pratley, R., Sathyapalan, T., Desouza, C., PIONEER 5 Investigators, Abramof, R., Alpenidze, D., Aronoff, S., Astamirova, K., Barker, B., Bedel, G., Belousova, L., Benson, M., Beshay, I., Biggs, W. & 34 others, , Jul 2019, In: The Lancet Diabetes and Endocrinology. 7, 7, p. 515-527Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extracellular Fluid Volume Expansion Uncovers a Natriuretic Action of GLP-1: A Functional GLP-1–Renal Axis in Man
Asmar, A., Cramon, P. K., Simonsen, L., Asmar, M., Sorensen, Charlotte Mehlin, Madsbad, Sten, Moro, C., Hartmann, Bolette, Jensen, B. L., Holst, Jens Juul & Bülow, J., Jul 2019, In: The Journal of clinical endocrinology and metabolism. 104, 7, p. 2509–2519Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cardiovascular risk reduction with once-weekly semaglutide in subjects with type 2 diabetes: A post hoc analysis of gender, age, and baseline CV risk profile in the SUSTAIN 6 trial
Leiter, L. A., Bain, S. C., Hramiak, I., Jódar, E., Madsbad, Sten, Gondolf, T., Hansen, T., Holst, I. & Lingvay, I., Jun 2019, In: Cardiovascular Diabetology. 18, 12 p., 73.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liraglutide for the prevention of major adverse cardiovascular events in diabetic patients
Madsbad, Sten, May 2019, In: Expert Review of Cardiovascular Therapy. 17, 5, p. 377-387 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Metabolic Health in Severely Obese Subjects: A Descriptive Study
Worm, Dorte, Madsbad, Sten & Hansen, D. L., Mar 2019, In: Metabolic Syndrome and Related Disorders. 17, 2, p. 115-119 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of DPP-4-protected GLP-1 (7-36) on coronary microvascular function in obese adults
Nilsson, M., Bové, K. B., Suhrs, E., Hermann, T., Madsbad, Sten, Holst, Jens Juul, Prescott, Eva & Zander, M., Mar 2019, In: IJC Heart and Vasculature. 22, p. 139-144Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of liraglutide on body weight and microvascular function in non-diabetic overweight women with coronary microvascular dysfunction
Suhrs, H. E., Raft, K. F., Bové, K., Madsbad, Sten, Holst, Jens Juul, Zander, M. & Prescott, Eva, 2 Jan 2019, In: International Journal of Cardiology. 283, p. 28-34Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A carbohydrate-reduced high-protein diet improves HbA1c and liver fat content in weight stable participants with type 2 diabetes: a randomised controlled trial
fbg982, fbg982, Samkani, A., Petersen, A. D., Thomsen, M. N., Astrup, A., Chabanova, E., Frystyk, J., Holst, Jens Juul, Thomsen, Henrik S., Madsbad, Sten, Larsen, T. M., Haugaard, Steen Bendix & Krarup, T., 2019, In: Diabetologia. 62, 11, p. 2066-2078 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assessment of Islet Alphaand beta-cell function
Madsbad, Sten & Holst, Jens Juul, 2019, Translational Research Methods in Diabetes, Obesity, and Nonalcoholic Fatty Liver Disease: A Focus on Early Phase Clinical Drug Development. Springer, p. 37-74 38 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Bariatric surgery-which procedure is the optimal choice?
Madsbad, Sten & Holst, Jens Juul, 2019, In: Lancet. 393, 10178, p. 1263-1264Research output: Contribution to journal › Comment/debate › Research
- Published
Effect of bariatric surgery on plasma GDF15 in humans
Kleinert, Maximilian, Bojsen-Møller, K. N., Jørgensen, N. B., Svane, M. S., Martinussen, C., Kiens, Bente, Wojtaszewski, Jørgen F P, Madsbad, Sten, Richter, Erik A. & Clemmensen, Christoffer, 2019, In: American Journal of Physiology: Endocrinology and Metabolism. 316, 4, p. E615-E621 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of liraglutide on estimates of lipolysis and lipid oxidation in obese patients with stable coronary artery disease and newly diagnosed type 2 diabetes: A randomized trial
Anholm, C., Kumarathurai, P., Samkani, A., Pedersen, L. R., Boston, R. C., Nielsen, Olav Wendelboe, Kristiansen, O. P., Fenger, M., Madsbad, Sten, Sajadieh, Ahmad & Haugaard, Steen Bendix, 2019, In: Diabetes, Obesity and Metabolism. 21, 8, p. 2012-2016 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-2 and GIP exert separate effects on bone turnover: A randomized, placebo-controlled, crossover study in healthy young men
Skov-Jeppesen, Kirsa, Svane, M. S., Martinussen, C., Gabe, M. B. N., Gasbjerg, Lærke Smidt, Veedfald, Simon, Bojsen-Møller, K. N., Madsbad, Sten, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2019, In: Bone. 125, p. 178-185Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Determinants of Weight Loss After Bariatric Surgery
Aasbrenn, M., Schnurr, T. M., Have, C. T., Svendstrup, M., Hansen, D. L., Worm, Dorte, Balslev-Harder, M., Hollensted, M., Grarup, Niels, Burgdorf, K. S., drb459, drb459, Pedersen, Oluf Borbye, Sørensen, Thorkild I.A., Fenger, M., Madsbad, Sten & Hansen, Torben, 2019, In: Obesity Surgery. 29, 8, p. 2554-2561 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glukagonlignende peptid 1-receptoragonisten semaglutid
Boje, A. D., Juhl, C. R., Torekov, Signe Sørensen & Madsbad, Sten, 2019, In: Ugeskrift for Laeger. 181, 5 p., V03190155.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liraglutide improves the beta-cell function without increasing insulin secretion during a mixed meal in patients, who exhibit well-controlled type 2 diabetes and coronary artery disease
Anholm, C., Kumarathurai, P., Jurs, A., Pedersen, L. R., Nielsen, Olav Wendelboe, Kristiansen, O. P., Fenger, M., Holst, Jens Juul, Madsbad, Sten, Sajadieh, Ahmad & Haugaard, Steen Bendix, 2019, In: Diabetology & Metabolic Syndrome. 11, 12 p., 42.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liraglutide preserved insulin secretion in adults with newly diagnosed type 1 diabetes: the NewLira trial: [Meeting Abstract}
Dejgaard, T. F., Frandsen, C., Kielgast, U., Andersen, H. U., Thorsteinsson, B., Krarup, T., Holst, Jens Juul & Madsbad, Sten, 2019, In: Diabetologia. 62, Supl. 1/SI, p. S75-S75 145.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Liraglutide-Induced Weight Loss May be Affected by Autonomic Regulation in Type 1 Diabetes
Hansen, C. S., Frandsen, C. S., Fleischer, J., Vistisen, D., Holst, Jens Juul, Tarnow, L., Knop, Filip Krag, Madsbad, Sten, Andersen, H. U. & Dejgaard, T. F., 2019, In: Frontiers in Endocrinology. 10, 9 p., 242.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms involved in follistatin-induced hypertrophy and increased insulin action in skeletal muscle
Han, X., Møller, Lisbeth L V, De Groote, E., Bojsen-Møller, K. N., Davey, J., Henriquez-Olguín, Carlos, Li, Z., Knudsen, Jonas Roland, Jensen, Thomas Elbenhardt, Madsbad, Sten, Gregorevic, P., Richter, Erik A. & Sylow, Lykke, 2019, In: Journal of Cachexia, Sarcopenia and Muscle. 10, 6, p. 1241-1257 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms of action of a carbohydrate-reduced, high-protein diet in reducing the risk of postprandial hypoglycemia after Roux-en-Y gastric bypass surgery
Kandel, D., Bojsen-Møller, K. N., Svane, M. S., Samkani, A., Astrup, A., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2019, In: American Journal of Clinical Nutrition. 110, 2, p. 296-304 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular mechanisms in skeletal muscle underlying insulin resistance in women who are lean with polycystic ovary syndrome
Hansen, S. L., Svendsen, P. F., Jeppesen, J. F., Høeg, L. D., Andersen, Nicoline Resen, Kristensen, Jonas Møller, Nilas, L., Lundsgaard, Anne-Marie, Wojtaszewski, Jørgen F P, Madsbad, Sten & Kiens, Bente, 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 5, p. 1841-1854 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phosphatidylcholine and its relation to apolipoproteins A-1 and B changes after Roux-en-Y gastric bypass: a cohort study
Carlsson, E. R., Allin, K. H., Madsbad, Sten & Fenger, M., 2019, In: Lipids in Health and Disease. 18, 11 p., 169.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial Nutrient Handling and Gastrointestinal Hormone Secretion After Roux-en-Y Gastric Bypass vs Sleeve Gastrectomy
Svane, M. S., Bojsen-Moller, K. N., Martinussen, C., Dirksen, C., Madsen, J. L., Reitelseder, S., Holm, L., Rehfeld, Jens Frederik, Kristiansen, V. B., van Hall, Gerrit, Holst, Jens Juul & Madsbad, Sten, 2019, In: Gastroenterology. 156, 6, p. 1627-1641Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pros and cons of Roux en-Y gastric bypass surgery in obese patients with type 2 diabetes
Justinussen, T., Madsbad, Sten, Holst, Jens Juul & Bojsen-Moller, K. N., 2019, In: Expert Review of Endocrinology & Metabolism. 14, 4, p. 243-257Research output: Contribution to journal › Review › Research › peer-review
- Published
Protocol for a randomised controlled trial of the combined effects of the GLP-1 receptor agonist liraglutide and exercise on maintenance of weight loss and health after a very low-calorie diet
Jensen, Simon Birk Kjær, Lundgren, J. R., Janus, C., Juhl, C. R., Olsen, L. M., Rosenkilde, M., Holst, Jens Juul, Stallknecht, Bente Merete, Madsbad, Sten & Torekov, Signe Sørensen, 2019, In: BMJ Open. 9, 11, 10 p., e031431.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sustained Improvements in Glucose Metabolism Late After Roux-En-Y Gastric Bypass Surgery in Patients with and Without Preoperative Diabetes
Jørgensen, N. B., Bojsen-Møller, K. N., Dirksen, C., Martinussen, C., Svane, M. S., Kristiansen, V. B., Holst, Jens Juul & Madsbad, Sten, 2019, In: Scientific Reports. 9, 1, 10 p., 15154.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Hepatic Insulin Clearance in Regulation of Systemic Insulin Concentrations—Role of Carbohydrate and Energy Availability
Bojsen-Møller, K. N., Lundsgaard, Anne-Marie, Madsbad, Sten, Kiens, Bente & Holst, Jens Juul, Nov 2018, In: Diabetes. 67, 11, p. 2129-2136 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms in bariatric surgery: Gut hormones, diabetes resolution, and weight loss
Holst, Jens Juul, Madsbad, Sten, Bojsen-Møller, K. N., Svane, M. S., Jørgensen, N. B., Dirksen, C. & Martinussen, C., May 2018, In: Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery. 14, 5, p. 708-714 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A carbohydrate-reduced high-protein diet acutely decreases postprandial and diurnal glucose excursions in type 2 diabetes patients
Samkani, A., fbg982, fbg982, Kandel, D., Kjaer, S., Astrup, A., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten, Rehfeld, Jens Frederik, Haugaard, Steen Bendix & Krarup, T., 2018, In: British Journal of Nutrition. 119, 8, p. 910-917 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute effects of dietary carbohydrate restriction on glycemia, lipemia and appetite regulating hormones in normal-weight to obese subjects
Samkani, A. A., fbg982, fbg982, Thomsen, M. N., Astrup, A., Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten, Rehfeld, Jens Frederik, Krarup, T. & Haugaard, Steen Bendix, 2018, In: Nutrients. 10, 9, 14 p., 1285.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changes in serum sphingomyelin after Roux-en-Y gastric bypass surgery are related to diabetes status
Carlsson, E. R., Grundtvig, J. L. G., Madsbad, Sten & Fenger, M., 2018, In: Frontiers in Endocrinology. 9, APR, 172.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cholecystokinin secretion is suppressed by glucagon-like peptide-1: clue to the mechanism of the adverse gallbladder events of GLP-1-derived drugs
Rehfeld, Jens Frederik, Knop, Filip Krag, Asmar, A., Madsbad, Sten, Holst, Jens Juul & Asmar, M., 2018, In: Scandinavian Journal of Gastroenterology. 53, 12, p. 1429-1432Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Preceding Ethanol Intake on Glucose Response to Low-Dose Glucagon in Individuals With Type 1 Diabetes: A Randomized, Placebo-Controlled, Crossover Study
Ranjan, A., Nørgaard, Kirsten, Tetzschner, R., Steineck, I. I. K., Clausen, T. R., Holst, Jens Juul, Madsbad, Sten & Schmidt, S., 2018, In: Diabetes Care. 41, 4, p. 797-806Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Erratum to semaglutide seems to be more effective the other GLP-1Ras
Holst, Jens Juul & Madsbad, Sten, 2018, In: Annals of Translational Medicine. 6, 3, p. 74Research output: Contribution to journal › Journal article › Research › peer-review
- Published
L cell secretory responses after gastric bypass surgery can be imitated in un-operated individuals by modulating carbohydrate digestion
Martinussen, C., Bojsen-Moller, K. N., Dirksen, C., Svane, M. S., Holst, Jens Juul & Madsbad, Sten, 2018, In: Diabetologia. 61, S1, p. S124-S125 244.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Metformin monotherapy for adults with type 2 diabetes mellitus
Gnesin, F., Thuesen, A. C., Kähler, L. K., Gluud, C., Madsbad, Sten & Hemmingsen, B., 2018, In: Cochrane Database of Systematic Reviews. 2018, 1, 18 p., CD012906.Research output: Contribution to journal › Review › Research › peer-review
- Published
Non-insulin pharmacological therapies for treating type 1 diabetes
Frandsen, C. S., Dejgaard, T. F., Madsbad, Sten & Holst, Jens Juul, 2018, In: Expert Opinion on Pharmacotherapy. 19, 9, p. 947-960Research output: Contribution to journal › Review › Research › peer-review
- Published
Overnight glucose control in people with type 1 diabetes
Boiroux, D., Duun-Henriksen, A. K., Schmidt, S., Nørgaard, Kirsten, Madsbad, Sten, Poulsen, N. K., Madsen, H. & Jørgensen, J. B., 2018, In: Biomedical Signal Processing and Control. 39, p. 503-512 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patients with Obesity Caused by Melanocortin-4 Receptor Mutations Can Be Treated with a Glucagon-like Peptide-1 Receptor Agonist
Iepsen, E. W., Zhang, J., Thomsen, Henrik S., Hansen, E. L., Hollensted, M., Madsbad, Sten, Hansen, Torben, Holst, Jens Juul, Holm, Jens-Christian & Torekov, Signe Sørensen, 2018, In: Cell Metabolism. 28, 1, p. 23-32.e3Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma Proteome Profiling Reveals Dynamics of Inflammatory and Lipid Homeostasis Markers after Roux-En-Y Gastric Bypass Surgery
Albrechtsen, Nicolai Jacob Wewer, Geyer, P. E., Doll, S., Treit, P. V., Bojsen-Møller, K. N., Martinussen, C., Jørgensen, N. B., Torekov, Signe Sørensen, Meier, F., Niu, Lili, Santos, A., Keilhauer, E. C., Holst, Jens Juul, Madsbad, Sten & Mann, Matthias, 2018, In: Cell Systems. 7, 6, p. 601-612Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preoperative High-Dose Methylprednisolone and Glycemic Control Early After Total Hip and Knee Arthroplasty: A Randomized, Double-Blind, Placebo-Controlled Trial
Lindberg-Larsen, V., Kehlet, Henrik, Bagger, J. & Madsbad, Sten, 2018, In: Anesthesia and Analgesia. 127, 4, p. 906-913 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Relationship between Optimum Mini‐doses of Glucagon and Insulin Levels when Treating Mild Hypoglycaemia in Patients with Type 1 Diabetes: A Simulation Study
Ranjan, A., Wendt, S. L., Schmidt, S., Madsbad, Sten, Holst, Jens Juul, Madsen, H., Knudsen, C. B., Jørgensen, J. B. & Nørgaard, Kirsten, 2018, In: Basic & Clinical Pharmacology & Toxicology. 122, 3, p. 322-330Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Separate effects of glucagon like peptide-2 (GLP-2) and glucose-dependent insulinotropic polypeptide (GIP) on bone remodelling
Skov-Jeppesen, Kirsa, Svane, M., Martinussen, C., Gabe, M., Gasbjerg, Lærke Smidt, Madsbad, Sten, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2018, In: Diabetologia. 61, S1, p. S245-S245 501.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Succesfuld behandling af KCNJ11-neonatal diabetes uden insulin
Gade-Rasmussen, B., Madsbad, Sten, Svane, M. S., Martinussen, C. & Hansen, Torben, 2018, In: Ugeskrift for Laeger. 180, 46, 2 p., V08180547.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Systems signatures reveal unique remission-path of Type 2 diabetes following Roux-en-Y gastric bypass surgery
Li, Q-R., Wang, Z-M., Albrechtsen, N. J. W., Wang, D-D., Su, Z-D., Gao, X-F., Wu, Q-Q., Zhang, H-P., Zhu, L., Li, R-X., Jacobsen, S., Jørgensen, N. B., Dirksen, C., Bojsen-Møller, K. N., Petersen, J. S., Madsbad, S., Clausen, T. R., Diderichsen, B., Chen, L-N., Holst, J. J. & 2 others, , 2018, In: EBioMedicine. 28, p. 234-240 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of DPP-4 protected GLP-1 (7-36) on coronary microcirculation in obese adults
Nilsson, M., Bove, K., Suhrs, E., Hermann, T., Madsbad, Sten, Holst, Jens Juul, Prescott, Eva & Zander, M., 2018, In: Diabetologia. 61, S1, p. S354-S355 729.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
The effect of metformin versus placebo in combination with insulin analogues on bone mineral density and trabecular bone score in patients with type 2 diabetes mellitus: a randomized placebo-controlled trial
Nordklint, A. K., Almdal, Thomas Peter, Vestergaard, P., Lundby-Christensen, L., Boesgaard, T. W., Breum, Leif, Gade-Rasmussen, B., Sneppen, S. B., Gluud, C., Hemmingsen, B., Jensen, T., Krarup, T., Madsbad, Sten, Mathiesen, Elisabeth, Perrild, Hans, Tarnow, L., Thorsteinsson, B., drb459, drb459, Lund, S. S. & Eiken, P., 2018, In: Osteoporosis International. 29, 11, p. 2517-2526Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment with GLP-1 Receptor Agonists
Madsbad, Sten & Holst, Jens Juul, 2018, Diabetes: Epidemiology, Genetics, Pathogenesis, Diagnosis, Prevention, and Treatment. Bonora, E. & DeFronzo, R. (eds.). Springer, 45 p. (Endocrinology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- 2017
- Published
Nutrient re-routing and altered gut-islet cell crosstalk may explain early relief of severe postprandial hypoglycaemia after reversal of Roux-en-Y gastric bypass
Svane, M. S., Toft-Nielsen, M. B., Kristiansen, V. B., Hartmann, Bolette, Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., Dec 2017, In: Diabetic Medicine Online. 34, 12, p. 1783-1787Research output: Contribution to journal › Letter › Research › peer-review
- Published
Semaglutide seems to be more effective the other GLP-1Ras
Holst, Jens Juul & Madsbad, Sten, Dec 2017, In: Annals of Translational Medicine. 5, 24, 5 p., 505.Research output: Contribution to journal › Comment/debate › Research
- Published
Cross-Validation of a Glucose-Insulin-Glucagon Pharmacodynamics Model for Simulation Using Data From Patients With Type 1 Diabetes
Wendt, S. L., Ranjan, A., Møller, J. K., Schmidt, S., Knudsen, C. B., Holst, Jens Juul, Madsbad, Sten, Madsen, H., Nørgaard, Kirsten & Jørgensen, J. B., 1 Nov 2017, In: Journal of Diabetes Science and Technology. 11, 6, p. 1101-1111 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production
Albrechtsen, N. J. W., Kuhre, R. E., Hornburg, D., Jensen, C. Z., Hornum, M., Dirksen, C., Svane, M., Gasbjerg, L. S., Jorgensen, N. B., Gabe, M. N., Balk-Moller, E., Albrechtsen, R., Winther-Sorensen, M., Galsgaard, K. D., Meissner, F., Jorsal, T., Lund, A., Vilsboll, T., Eliasen, R., Bojsen-Moller, K. N. & 9 others, , Nov 2017, In: Cell Reports. 21, 6, p. 1452-1460Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Short-term effects of a low carbohydrate diet on glycaemic variables and cardiovascular risk markers in patients with type 1 diabetes: A randomized open-label crossover trial
Ranjan, A., Schmidt, S., Damm-Frydenberg, C., Holst, Jens Juul, Madsbad, Sten & Nørgaard, Kirsten, Oct 2017, In: Diabetes, Obesity and Metabolism. 19, 10, p. 1479-1484Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A sandwich ELISA for measurement of the primary glucagon-like peptide-1 metabolite
Albrechtsen, Nicolai Jacob Wewer, Asmar, A., Jensen, F., Törang, S., Simonsen, L., Kuhre, Rune Ehrenreich, Asmar, M., Veedfald, Simon, Plamboeck, A., Knop, Filip Krag, Vilsbøll, Tina, Madsbad, Sten, Nauck, M. A., Deacon, Carolyn F., Bülow, J., Holst, Jens Juul & Hartmann, Bolette, 1 Sep 2017, In: American Journal of Physiology: Endocrinology and Metabolism. 313, 3, p. E284-E291Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fixed-ratio combination therapy with GLP-1 receptor agonist liraglutide and insulin degludec in people with type 2 diabetes
Østergaard, L., Frandsen, C. S., Dejgaard, T. F. & Madsbad, Sten, Jun 2017, In: Expert Review of Clinical Pharmacology. 10, 6, p. 621-632 12 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Effects of liraglutide on cardiovascular risk factors in patients with type 1 diabetes
Dejgaard, T. F., Johansen, N. B., Frandsen, C. S. S., Asmar, A., Tarnow, L., Knop, Filip Krag, Madsbad, Sten & Andersen, H. U., May 2017, In: Diabetes, Obesity and Metabolism. 19, 5, p. 734–738Research output: Contribution to journal › Letter › Research › peer-review
- Published
Effects of the glucagon-like peptide-1receptor agonist liraglutide on 24-h ambulatory blood pressure in patients with type 2 diabetes and stable coronary artery disease: A randomized, double-blind, placebo-controlled, crossover study
Kumarathurai, P., Anholm, C., Fabricius-Bjerre, A., Nielsen, Olav Wendelboe, Kristiansen, O., Madsbad, Sten, Haugaard, Steen Bendix & Sajadieh, Ahmad, May 2017, In: Journal of Hypertension. 35, 5, p. 1070-1078 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glycaemic control and weight loss with semaglutide in type 2 diabetes
Madsbad, Sten & Holst, Jens Juul, May 2017, In: The Lancet Diabetes and Endocrinology. 5, 5, p. 315-317 3 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Liraglutide as adjunct to insulin treatment in type 1 diabetes does not interfere with glycaemic recovery or gastric emptying rate during hypoglycaemia: a randomised, placebo-controlled, double-blind, parallel-group study
Frandsen, C. S., Dejgaard, T. F., Andersen, H. U., Holst, Jens Juul, Hartmann, Bolette, Thorsteinsson, B. & Madsbad, Sten, 17 Mar 2017, In: Diabetes, Obesity and Metabolism. 19, 6, p. 773-782 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of large weight reductions on measured and estimated kidney function
von Scholten, B. J., Persson, F., Svane, M. S., Hansen, T. W., Madsbad, Sten & Rossing, Peter, 6 Feb 2017, In: B M C Nephrology. 18, 7 p., 52.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chenodeoxycholic acid stimulates glucagon-like peptide-1 secretion in patients after Roux-en-Y gastric bypass
Nielsen, S., Svane, M. S., Kuhre, Rune Ehrenreich, Clausen, T. R., Kristiansen, V. B., Rehfeld, Jens Frederik, Holst, Jens Juul, Madsbad, Sten & Bojsen-Moller, K. N., Feb 2017, In: Physiological Reports. 5, 3, 11 p., e13140.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparative studies of insulin vs glucagon-like peptide-1 receptor agonists in patients initiating injectable therapy
Dejgaard, T. F. & Madsbad, Sten, Feb 2017, In: Diabetes, Obesity and Metabolism. 19, 2, p. 153-155 3 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Glucagon-like peptide-1 elicits vasodilation in adipose tissue and skeletal muscle in healthy men
Asmar, A., Asmar, M., Simonsen, L., Madsbad, Sten, Holst, Jens Juul, Hartmann, Bolette, Sorensen, Charlotte Mehlin & Bülow, J., Feb 2017, In: Physiological Reports. 5, 3, 12 p., e13073.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Liraglutide on Heart Rate and Heart Rate Variability: A Randomized, Double-Blind, Placebo-Controlled Crossover Study
Kumarathurai, P., Anholm, C., Larsen, B. S., Olsen, R. H., Madsbad, Sten, Kristiansen, O., Nielsen, Olav Wendelboe, Haugaard, Steen Bendix & Sajadieh, Ahmad, Jan 2017, In: Diabetes Care. 40, 1, p. 117-124 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased glucose-stimulated FGF21 response to oral glucose in obese non-diabetic subjects after Roux-en-Y Gastric Bypass
Vienberg, S. G., Jacobsen, S. H., Worm, D., Hvolris, L. E., Naver, L. P. S., Almdal, Thomas Peter, Hansen, D. L., Wulff, B. S., Clausen, T. R., Madsbad, Sten, Holst, Jens Juul & Andersen, B., Jan 2017, In: Clinical Endocrinology. 86, 1, p. 156-159 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low-Carbohydrate Diet Impairs the Effect of Glucagon in the Treatment of Insulin-Induced Mild Hypoglycemia: A Randomized Crossover Study
Ranjan, A., Schmidt, S., Damm-Frydenberg, C., Steineck, I., Clausen, T. R., Holst, Jens Juul, Madsbad, Sten & Nørgaard, Kirsten, Jan 2017, In: Diabetes Care. 40, 1, p. 132-135 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of weight reductions on estimated kidney function: Post-hoc analysis of two randomized trials
von Scholten, B. J., Davies, M. J., Persson, F., Hansen, T. W., Madsbad, Sten, Endahl, L., Jepsen, C. H. & Rossing, Peter, 2017, In: Journal of Diabetes and its Complications. 31, 7, p. 1164-1168Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Emerging drugs for the treatment of obesity
Martinussen, C., Bojsen-Møller, K. N., Svane, M. S., Dejgaard, T. F. & Madsbad, Sten, 2017, In: Expert Opinion on Emerging Drugs. 22, 1, p. 87-99 13 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Instrumentalization of eating improves weight loss maintenance in obesity
Christensen, Bodil Just, Iepsen, E. P. W., Lundgren, J. R., Holm, Lotte, Madsbad, Sten, Holst, Jens Juul & Torekov, Signe Sørensen, 2017, In: Obesity Facts. 10, 6, p. 633-647 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liraglutide effects on beta-cell, insulin sensitivity and glucose effectiveness in patients with stable coronary artery disease and newly diagnosed type 2 diabetes
Anholm, C., Kumarathurai, P., Pedersen, L. R., Nielsen, Olav Wendelboe, Kristiansen, O. P., Fenger, M., Madsbad, Sten, Sajadieh, Ahmad & Haugaard, Steen Bendix, 2017, In: Diabetes, Obesity and Metabolism. 19, 6, p. 850-857Research output: Contribution to journal › Journal article › Research › peer-review
- Published
S100A8/A9 (Calprotectin), Interleukin-6, and C-Reactive Protein in Obesity and Diabetes before and after Roux-en-Y Gastric Bypass Surgery
Lylloff, L., Bathum, L., Madsbad, Sten, Grundtvig, J. L. G., Nordgaard-Lassen, I. & Fenger, M., 2017, In: Obesity Facts. 10, 4, p. 386-395 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The impact of gastric bypass surgery on sex hormones and menstrual cycles in premenopausal women
Kjær, M. M., Madsbad, Sten, Hougaard, D. M., Cohen, A. S. & Nilas, L., 2017, In: Gynecological Endocrinology. 33, 2, p. 160-163 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment with liraglutide may improve markers of CVD reflected by reduced levels of apoB
pjx571, pjx571, Lundgren, Jens, Albrechtsen, Nicolai Jacob Wewer, Mahendran, Y., Iepsen, E. P. W., Finocchietto, P., Jonsson, Anna Elisabet, Madsbad, Sten, Holst, Jens Juul, drb459, drb459, Hansen, Torben & Torekov, Signe Sørensen, 2017, In: Obesity Science & Practice. 3, 4, p. 425-433 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variable reliability of surrogate measures of insulin sensitivity after Roux-en-Y gastric bypass
Bojsen-Møller, K. N., Dirksen, C., Svane, M. S., Jørgensen, N. B., Holst, Jens Juul, Richter, Erik A. & Madsbad, Sten, 2017, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 312, 5, p. R797-R805 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Proteomics reveals the effects of sustained weight loss on the human plasma proteome
Geyer, P. E., Albrechtsen, Nicolai Jacob Wewer, Tyanova, S., Grassl, N., Iepsen, E. P. W., Lundgren, J., Madsbad, Sten, Holst, Jens Juul, Torekov, Signe Sørensen & Mann, Matthias, 22 Dec 2016, In: Molecular Systems Biology. 12, 16 p., 901.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Weight loss and weight maintenance obtained with or without GLP-1 analogue treatment decrease branched chain amino acid levels
pjx571, pjx571, Iepsen, E. P. W., Galijatovic, E. A. A., Mahendran, Y., Lundgren, J. R., Jonsson, Anna Elisabet, Madsbad, Sten, Holst, Jens Juul, drb459, drb459, Hansen, Torben & Torekov, Signe Sørensen, Dec 2016, In: Metabolomics. 12, 12, p. 1-9 9 p., 181.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric bypass surgery reveals independency of obesity and diabetes melitus type 2
Fenger, M., Hansen, D. L., Worm, D., Hvolris, L. E., Kristiansen, V. B., Carlsson, E. R. & Madsbad, Sten, 9 Nov 2016, In: BMC Endocrine Disorders. 16, p. 1-10 10 p., 59.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Relationship Between Two Common Lipoprotein Lipase Variants and the Metabolic Syndrome and Its Individual Components
Vishram, J. K. K., Hansen, T. W., Torp-Pedersen, C., Madsbad, Sten, Jørgensen, T., Fenger, M., Lyngbæk, S. & Jeppesen, J., Nov 2016, In: Metabolic Syndrome and Related Disorders. 14, 9, p. 442-448 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Medicinsk vs. kirurgisk behandling af svært overvægtige patienter med type 2-diabetes
Svane, M. S., Bojsen-Møller, K. N. & Madsbad, Sten, 31 Oct 2016, In: Ugeskrift for Laeger. 178, 22, p. 2103-07 5 p., V06160418.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metformin and sulphonylurea (second- or third-generation) combination therapy for adults with type 2 diabetes mellitus
Madsen, K. S., Kähler, P., Kähler, L. K., Madsbad, Sten, Metzendorf, M. I., Richter, B. & Hemmingsen, B., 26 Sep 2016, In: Cochrane Database of Systematic Reviews. 2016, 9, CD012368.Research output: Contribution to journal › Review › Research › peer-review
- Published
Guidelines: Surgical or medical therapy for patients with obesity and T2DM?
Madsbad, Sten & Holst, Jens Juul, 1 Sep 2016, In: Nature Reviews Endocrinology. 12, 9, p. 500-502 3 p.Research output: Contribution to journal › Comment/debate › Communication
- Published
No Islet Cell Hyperfunction, but Altered Gut-Islet Regulation and Postprandial Hypoglycemia in Glucose-Tolerant Patients 3 Years After Gastric Bypass Surgery
Dirksen, C., Eiken, A., Bojsen-Møller, K. N., Svane, M. S., Martinussen, C., Jørgensen, N. B., Holst, Jens Juul & Madsbad, Sten, Sep 2016, In: Obesity Surgery. 26, 9, p. 2263-7 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Non-insulin drugs to treat hyperglycaemia in type 1 diabetes mellitus
Frandsen, C. S., Dejgaard, T. F. & Madsbad, Sten, Sep 2016, In: The Lancet Diabetes and Endocrinology. 4, 9, p. 766-780 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Retinal characteristics during 1 year of insulin pump therapy in type 1 diabetes: a prospective, controlled, observational study
Klefter, O. N., Hommel, E., Munch, I. C., Nørgaard, Kirsten, Madsbad, Sten & Larsen, Michael, Sep 2016, In: Acta Ophthalmologica. 94, 6, p. 540-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peptide YY and glucagon-like peptide-1 contribute to decreased food intake after Roux-en-Y gastric bypass surgery
Svane, M. S., Jørgensen, N. B., Bojsen-Møller, K. N., Dirksen, C., Nielsen, S., Kristiansen, V. B., Toräng, S., Albrechtsen, Nicolai Jacob Wewer, Rehfeld, Jens Frederik, Hartmann, Bolette, Madsbad, Sten & Holst, Jens Juul, 30 Aug 2016, In: International Journal of Obesity. 40, p. 1699–1706Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clinical use of the co-formulation of insulin degludec and insulin aspart
Kumar, A., Awata, T., Bain, S. C., Ceriello, A., Fulcher, G. R., Unnikrishnan, A. G., Arechavaleta, R., Gonzalez-Gálvez, G., Hirose, T., Home, P. D., Kaku, K., Litwak, L., Madsbad, Sten, Pinget, M., Mehta, C. R., Mithal, A., Tambascia, M., Tibaldi, J. & Christiansen, J. S., Aug 2016, In: International Journal of Clinical Practice. 70, 8, p. 657-67 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Effects of the glucagon-like peptide-1 receptor agonist liraglutide on systolic function in patients with coronary artery disease and type 2 diabetes: a randomized double-blind placebo-controlled crossover study
Kumarathurai, P., Anholm, C., Nielsen, Olav Wendelboe, Kristiansen, O. P., Mølvig, J., Madsbad, Sten, Haugaard, Steen Bendix & Sajadieh, Ahmad, 26 Jul 2016, In: Cardiovascular Diabetology. 15, 10 p., 105.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms of surgical control of type 2 diabetes: GLP-1 is key factor
Holst, Jens Juul & Madsbad, Sten, Jul 2016, In: Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery. 12, 6, p. 1236-42 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Successful weight loss maintenance includes long-term increased meal responses of GLP-1 and PYY3-36
Iepsen, E. W., Lundgren, J., Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, Jun 2016, In: European Journal of Endocrinology. 174, 6, p. 775-784 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Instrumentalization of eating improves weight loss maintenance in obesity
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Treatment with liraglutide may improve markers of CVD reflected by reduced levels of apoB
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Roux-en-Y gastric bypass surgery of morbidly obese patients induces swift and persistent changes of the individual gut microbiota
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