Concentrations of the acute phase reactants high-sensitive C-reactive protein and YKL-40 and of interleukin-6 before and after treatment in patients with acromegaly and growth hormone deficiency
Research output: Contribution to journal › Journal article › Research › peer-review
Acromegaly is accompanied by increased cardiovascular mortality and a cluster of proatherogenic risk factors. In the general population, ischaemic heart disease (IHD) is associated with elevated levels of inflammatory markers. The acute phase reactant (APR) C-reactive protein (CRP) has been reported to be reduced in acromegaly and increase after treatment, suggesting that excess of GH/IGF-I could have anti-inflammatory effects. This is in accordance with results obtained in patients with growth hormone deficiency (GHD), where increased levels of CRP have been reported.
| Original language | English |
|---|---|
| Journal | Clinical Endocrinology |
| Volume | 67 |
| Issue number | 6 |
| Pages (from-to) | 909-16 |
| Number of pages | 8 |
| ISSN | 0300-0664 |
| DOIs | |
| Publication status | Published - Dec 2007 |
- Acromegaly, Adipokines, Adolescent, Adult, C-Reactive Protein, Case-Control Studies, Dwarfism, Pituitary, Female, Human Growth Hormone, Humans, Insulin-Like Growth Factor I, Interleukin-6, Lectins, Male, Middle Aged, Young Adult
Research areas
ID: 92190487