Standard
Pleiotropic effects of GIP on islet function involve osteopontin. / Lyssenko, Valeriya; Eliasson, Lena; Kotova, Olga; Pilgaard, Kasper; Wierup, Nils; Salehi, Albert; Wendt, Anna; Jonsson, Anna Elisabet; De Marinis, Yang Z; Berglund, Lisa M; Taneera, Jalal; Balhuizen, Alexander; Hansson, Ola; Osmark, Peter; Dunér, Pontus; Brøns, Charlotte; Stancáková, Alena; Kuusisto, Johanna; Bugliani, Marco; Saxena, Richa; Ahlqvist, Emma; Kieffer, Timothy J; Tuomi, Tiinamaija; Isomaa, Bo; Melander, Olle; Sonestedt, Emily; Orho-Melander, Marju; Nilsson, Peter; Bonetti, Sara; Bonadonna, Riccardo; Miccoli, Roberto; Delprato, Stefano; Marchetti, Piero; Madsbad, Sten; Poulsen, Pernille; Vaag, Allan; Laakso, Markku; Gomez, Maria F; Groop, Leif.
In:
Diabetes, Vol. 60, No. 9, 09.2011, p. 2424-33.
Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
Lyssenko, V, Eliasson, L, Kotova, O, Pilgaard, K, Wierup, N, Salehi, A, Wendt, A
, Jonsson, AE, De Marinis, YZ, Berglund, LM, Taneera, J, Balhuizen, A, Hansson, O, Osmark, P, Dunér, P, Brøns, C, Stancáková, A, Kuusisto, J, Bugliani, M, Saxena, R, Ahlqvist, E, Kieffer, TJ, Tuomi, T, Isomaa, B, Melander, O, Sonestedt, E, Orho-Melander, M, Nilsson, P, Bonetti, S, Bonadonna, R, Miccoli, R, Delprato, S, Marchetti, P
, Madsbad, S, Poulsen, P
, Vaag, A, Laakso, M, Gomez, MF & Groop, L 2011, '
Pleiotropic effects of GIP on islet function involve osteopontin',
Diabetes, vol. 60, no. 9, pp. 2424-33.
https://doi.org/10.2337/db10-1532APA
Lyssenko, V., Eliasson, L., Kotova, O., Pilgaard, K., Wierup, N., Salehi, A., Wendt, A.
, Jonsson, A. E., De Marinis, Y. Z., Berglund, L. M., Taneera, J., Balhuizen, A., Hansson, O., Osmark, P., Dunér, P., Brøns, C., Stancáková, A., Kuusisto, J., Bugliani, M., ... Groop, L. (2011).
Pleiotropic effects of GIP on islet function involve osteopontin.
Diabetes,
60(9), 2424-33.
https://doi.org/10.2337/db10-1532Vancouver
Lyssenko V, Eliasson L, Kotova O, Pilgaard K, Wierup N, Salehi A et al.
Pleiotropic effects of GIP on islet function involve osteopontin.
Diabetes. 2011 Sep;60(9):2424-33.
https://doi.org/10.2337/db10-1532Author
Lyssenko, Valeriya ; Eliasson, Lena ; Kotova, Olga ; Pilgaard, Kasper ; Wierup, Nils ; Salehi, Albert ; Wendt, Anna ; Jonsson, Anna Elisabet ; De Marinis, Yang Z ; Berglund, Lisa M ; Taneera, Jalal ; Balhuizen, Alexander ; Hansson, Ola ; Osmark, Peter ; Dunér, Pontus ; Brøns, Charlotte ; Stancáková, Alena ; Kuusisto, Johanna ; Bugliani, Marco ; Saxena, Richa ; Ahlqvist, Emma ; Kieffer, Timothy J ; Tuomi, Tiinamaija ; Isomaa, Bo ; Melander, Olle ; Sonestedt, Emily ; Orho-Melander, Marju ; Nilsson, Peter ; Bonetti, Sara ; Bonadonna, Riccardo ; Miccoli, Roberto ; Delprato, Stefano ; Marchetti, Piero ; Madsbad, Sten ; Poulsen, Pernille ; Vaag, Allan ; Laakso, Markku ; Gomez, Maria F ; Groop, Leif. / Pleiotropic effects of GIP on islet function involve osteopontin. In: Diabetes. 2011 ; Vol. 60, No. 9. pp. 2424-33.
Bibtex
@article{75b9e8286a374a289d937737e9a189d9,
title = "Pleiotropic effects of GIP on islet function involve osteopontin",
abstract = "The incretin hormone GIP (glucose-dependent insulinotropic polypeptide) promotes pancreatic β-cell function by potentiating insulin secretion and β-cell proliferation. Recently, a combined analysis of several genome-wide association studies (Meta-analysis of Glucose and Insulin-Related Traits Consortium [MAGIC]) showed association to postprandial insulin at the GIP receptor (GIPR) locus. Here we explored mechanisms that could explain the protective effects of GIP on islet function.",
keywords = "Alleles, Diabetes Mellitus, Type 2, Gastric Inhibitory Polypeptide, Genome-Wide Association Study, Glucagon-Like Peptide 1, Humans, Insulin, Insulin-Secreting Cells, Islets of Langerhans, Male, Osteopontin",
author = "Valeriya Lyssenko and Lena Eliasson and Olga Kotova and Kasper Pilgaard and Nils Wierup and Albert Salehi and Anna Wendt and Jonsson, {Anna Elisabet} and {De Marinis}, {Yang Z} and Berglund, {Lisa M} and Jalal Taneera and Alexander Balhuizen and Ola Hansson and Peter Osmark and Pontus Dun{\'e}r and Charlotte Br{\o}ns and Alena Stanc{\'a}kov{\'a} and Johanna Kuusisto and Marco Bugliani and Richa Saxena and Emma Ahlqvist and Kieffer, {Timothy J} and Tiinamaija Tuomi and Bo Isomaa and Olle Melander and Emily Sonestedt and Marju Orho-Melander and Peter Nilsson and Sara Bonetti and Riccardo Bonadonna and Roberto Miccoli and Stefano Delprato and Piero Marchetti and Sten Madsbad and Pernille Poulsen and Allan Vaag and Markku Laakso and Gomez, {Maria F} and Leif Groop",
year = "2011",
month = sep,
doi = "10.2337/db10-1532",
language = "English",
volume = "60",
pages = "2424--33",
journal = "Diabetes",
issn = "0012-1797",
publisher = "American Diabetes Association",
number = "9",
}
RIS
TY - JOUR
T1 - Pleiotropic effects of GIP on islet function involve osteopontin
AU - Lyssenko, Valeriya
AU - Eliasson, Lena
AU - Kotova, Olga
AU - Pilgaard, Kasper
AU - Wierup, Nils
AU - Salehi, Albert
AU - Wendt, Anna
AU - Jonsson, Anna Elisabet
AU - De Marinis, Yang Z
AU - Berglund, Lisa M
AU - Taneera, Jalal
AU - Balhuizen, Alexander
AU - Hansson, Ola
AU - Osmark, Peter
AU - Dunér, Pontus
AU - Brøns, Charlotte
AU - Stancáková, Alena
AU - Kuusisto, Johanna
AU - Bugliani, Marco
AU - Saxena, Richa
AU - Ahlqvist, Emma
AU - Kieffer, Timothy J
AU - Tuomi, Tiinamaija
AU - Isomaa, Bo
AU - Melander, Olle
AU - Sonestedt, Emily
AU - Orho-Melander, Marju
AU - Nilsson, Peter
AU - Bonetti, Sara
AU - Bonadonna, Riccardo
AU - Miccoli, Roberto
AU - Delprato, Stefano
AU - Marchetti, Piero
AU - Madsbad, Sten
AU - Poulsen, Pernille
AU - Vaag, Allan
AU - Laakso, Markku
AU - Gomez, Maria F
AU - Groop, Leif
PY - 2011/9
Y1 - 2011/9
N2 - The incretin hormone GIP (glucose-dependent insulinotropic polypeptide) promotes pancreatic β-cell function by potentiating insulin secretion and β-cell proliferation. Recently, a combined analysis of several genome-wide association studies (Meta-analysis of Glucose and Insulin-Related Traits Consortium [MAGIC]) showed association to postprandial insulin at the GIP receptor (GIPR) locus. Here we explored mechanisms that could explain the protective effects of GIP on islet function.
AB - The incretin hormone GIP (glucose-dependent insulinotropic polypeptide) promotes pancreatic β-cell function by potentiating insulin secretion and β-cell proliferation. Recently, a combined analysis of several genome-wide association studies (Meta-analysis of Glucose and Insulin-Related Traits Consortium [MAGIC]) showed association to postprandial insulin at the GIP receptor (GIPR) locus. Here we explored mechanisms that could explain the protective effects of GIP on islet function.
KW - Alleles
KW - Diabetes Mellitus, Type 2
KW - Gastric Inhibitory Polypeptide
KW - Genome-Wide Association Study
KW - Glucagon-Like Peptide 1
KW - Humans
KW - Insulin
KW - Insulin-Secreting Cells
KW - Islets of Langerhans
KW - Male
KW - Osteopontin
U2 - 10.2337/db10-1532
DO - 10.2337/db10-1532
M3 - Journal article
C2 - 21810601
VL - 60
SP - 2424
EP - 2433
JO - Diabetes
JF - Diabetes
SN - 0012-1797
IS - 9
ER -
