Polycystic ovary syndrome and low-grade inflammation with special reference to YKL-40

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Polycystic ovary syndrome and low-grade inflammation with special reference to YKL-40. / Aziz, M; Wissing, M L M; Naver, K V; Faber, J; Skouby, S O.

In: Gynecological Endocrinology, Vol. 30, No. 4, 04.2014, p. 311-315.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Aziz, M, Wissing, MLM, Naver, KV, Faber, J & Skouby, SO 2014, 'Polycystic ovary syndrome and low-grade inflammation with special reference to YKL-40', Gynecological Endocrinology, vol. 30, no. 4, pp. 311-315. https://doi.org/10.3109/09513590.2013.879854

APA

Aziz, M., Wissing, M. L. M., Naver, K. V., Faber, J., & Skouby, S. O. (2014). Polycystic ovary syndrome and low-grade inflammation with special reference to YKL-40. Gynecological Endocrinology, 30(4), 311-315. https://doi.org/10.3109/09513590.2013.879854

Vancouver

Aziz M, Wissing MLM, Naver KV, Faber J, Skouby SO. Polycystic ovary syndrome and low-grade inflammation with special reference to YKL-40. Gynecological Endocrinology. 2014 Apr;30(4):311-315. https://doi.org/10.3109/09513590.2013.879854

Author

Aziz, M ; Wissing, M L M ; Naver, K V ; Faber, J ; Skouby, S O. / Polycystic ovary syndrome and low-grade inflammation with special reference to YKL-40. In: Gynecological Endocrinology. 2014 ; Vol. 30, No. 4. pp. 311-315.

Bibtex

@article{7b4c97cb33b34dfcb20cd5599cbefb99,
title = "Polycystic ovary syndrome and low-grade inflammation with special reference to YKL-40",
abstract = "OBJECTIVE: To evaluate the plasma level of YKL-40 in a Danish polycystic ovary syndrome (PCOS) population and to investigate whether YKL-40 is associated with CVD risk factors such as waist circumference, body mass index (BMI), insulin resistance (IR), fasting glucose, fasting insulin, blood lipids and CRP.DESIGN: Cross-sectional study.SETTING: Gynecological clinics at three Danish University Hospitals.PATIENTS: One hundred seventy-one premenopausal women with PCOS recruited consecutively from April 2010 to February 2012. PCOS was diagnosed according to the Rotterdam criteria.MAIN OUTCOME MEASURES: Plasma level of YKL-40 in four phenotypes of PCOS defined by BMI and IR.RESULTS: No statistically significant difference was observed in the plasma level of YKL-40 across the four BMI/IR-phenotypes. Positive associations were observed between YKL-40 and BMI, total and free testosterone, triglycerides, and CRP. Total and free testosterone were independent predictors of YKL-40.CONCLUSION: YKL-40, the marker of low-grade inflammation is not increased in women with PCOS.",
keywords = "Adipokines, Adolescent, Adult, Biological Markers, Body Mass Index, C-Reactive Protein, Cross-Sectional Studies, Denmark, Female, Humans, Inflammation, Insulin, Insulin Resistance, Lectins, Polycystic Ovary Syndrome, Prospective Studies, Regression Analysis, Triglycerides, Waist Circumference, Young Adult",
author = "M Aziz and Wissing, {M L M} and Naver, {K V} and J Faber and Skouby, {S O}",
year = "2014",
month = apr,
doi = "10.3109/09513590.2013.879854",
language = "English",
volume = "30",
pages = "311--315",
journal = "Gynecological Endocrinology",
issn = "0951-3590",
publisher = "Taylor & Francis",
number = "4",

}

RIS

TY - JOUR

T1 - Polycystic ovary syndrome and low-grade inflammation with special reference to YKL-40

AU - Aziz, M

AU - Wissing, M L M

AU - Naver, K V

AU - Faber, J

AU - Skouby, S O

PY - 2014/4

Y1 - 2014/4

N2 - OBJECTIVE: To evaluate the plasma level of YKL-40 in a Danish polycystic ovary syndrome (PCOS) population and to investigate whether YKL-40 is associated with CVD risk factors such as waist circumference, body mass index (BMI), insulin resistance (IR), fasting glucose, fasting insulin, blood lipids and CRP.DESIGN: Cross-sectional study.SETTING: Gynecological clinics at three Danish University Hospitals.PATIENTS: One hundred seventy-one premenopausal women with PCOS recruited consecutively from April 2010 to February 2012. PCOS was diagnosed according to the Rotterdam criteria.MAIN OUTCOME MEASURES: Plasma level of YKL-40 in four phenotypes of PCOS defined by BMI and IR.RESULTS: No statistically significant difference was observed in the plasma level of YKL-40 across the four BMI/IR-phenotypes. Positive associations were observed between YKL-40 and BMI, total and free testosterone, triglycerides, and CRP. Total and free testosterone were independent predictors of YKL-40.CONCLUSION: YKL-40, the marker of low-grade inflammation is not increased in women with PCOS.

AB - OBJECTIVE: To evaluate the plasma level of YKL-40 in a Danish polycystic ovary syndrome (PCOS) population and to investigate whether YKL-40 is associated with CVD risk factors such as waist circumference, body mass index (BMI), insulin resistance (IR), fasting glucose, fasting insulin, blood lipids and CRP.DESIGN: Cross-sectional study.SETTING: Gynecological clinics at three Danish University Hospitals.PATIENTS: One hundred seventy-one premenopausal women with PCOS recruited consecutively from April 2010 to February 2012. PCOS was diagnosed according to the Rotterdam criteria.MAIN OUTCOME MEASURES: Plasma level of YKL-40 in four phenotypes of PCOS defined by BMI and IR.RESULTS: No statistically significant difference was observed in the plasma level of YKL-40 across the four BMI/IR-phenotypes. Positive associations were observed between YKL-40 and BMI, total and free testosterone, triglycerides, and CRP. Total and free testosterone were independent predictors of YKL-40.CONCLUSION: YKL-40, the marker of low-grade inflammation is not increased in women with PCOS.

KW - Adipokines

KW - Adolescent

KW - Adult

KW - Biological Markers

KW - Body Mass Index

KW - C-Reactive Protein

KW - Cross-Sectional Studies

KW - Denmark

KW - Female

KW - Humans

KW - Inflammation

KW - Insulin

KW - Insulin Resistance

KW - Lectins

KW - Polycystic Ovary Syndrome

KW - Prospective Studies

KW - Regression Analysis

KW - Triglycerides

KW - Waist Circumference

KW - Young Adult

U2 - 10.3109/09513590.2013.879854

DO - 10.3109/09513590.2013.879854

M3 - Journal article

C2 - 24471491

VL - 30

SP - 311

EP - 315

JO - Gynecological Endocrinology

JF - Gynecological Endocrinology

SN - 0951-3590

IS - 4

ER -

ID: 138135940