Gitte Moos Knudsen

Gitte Moos Knudsen

Clinical Professor

Member of:

  • Neurology


  1. Published
  2. Published

    Radiosynthesis and preclinical evaluation of [11 C]Cimbi-701 - Towards the imaging of cerebral 5-HT7 receptors

    L 'Estrade, E. T., Shalgunov, Vladimir, Edgar, F. G., Strebl-Bantillo, M. G., Xiong, M., Crestey, F., Neelamegam, R., Dyssegaard, A., Lehel, S., Erlandsson, M., Ohlsson, T., Hooker, J. M., Knudsen, Gitte Moos, Herth, Matthias Manfred & Hansen, H. D., 2020, In: Journal of Labelled Compounds and Radiopharmaceuticals. 63, p. 46-55

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Towards selective CNS PET Imaging of the 5-HT7 Receptor System: Past, Present and Future

    L'Estrade, E. T., Erlandsson, M., Edgar, F. G., Ohlsson, T., Knudsen, Gitte Moos & Herth, Matthias Manfred, 2020, In: Neuropharmacology. 172, 107830.

    Research output: Contribution to journalReviewResearchpeer-review

  4. Published

    Synthesis and Pharmacological Evaluation of [C-11]4-Methoxy-N-[2-(thiophen-2-yl) imidazo[1,2-a] pyridin-3-yl]benzamide as a Brain Penetrant PET Ligand Selective for the delta-Subunit-Containing gamma-Aminobutyric Acid Type A Receptors

    L'Estrade, E. T., Hansen, H. D., Falk-Petersen, C., Haugaard, A., Griem-Krey, Nane, Jung, S., Lueddens, H., Schirmeister, T., Erlandsson, M., Ohlsson, T., Knudsen, Gitte Moos, Herth, Matthias Manfred, Wellendorph, Petrine & Frølund, Bente, May 2019, In: ACS Omega. 4, 5, p. 8846-8851

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    PET radiotracer translation from rats to higher species, using an increased-throughput in vivo evaluation strategy

    L'Estrade, E. T., Xiong, M., Petersen, I., Shalgunov, Vladimir, Edgar, F. G., Hansen, H., Erlandsson, M., Ohlsson, T., Knudsen, Gitte Moos, Palner, M. & Herth, Matthias Manfred, May 2019, p. S389-S390.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  6. Published

    Chronic escitalopram in healthy volunteers has specific effects on reinforcement sensitivity: a double-blind, placebo-controlled semi-randomised study

    Langley, C., Armand, Sophia, Luo, Q., Savulich, G., Segerberg, T., Søndergaard, A., Pedersen, E. B., Svart, N., Overgaard-Hansen, O., Johansen, A., Borgsted, C., Cardinal, R. N., Robbins, T. W., Stenbæk, Dea Siggaard, Knudsen, Gitte Moos & Sahakian, B. J., 2023, In: Neuropsychopharmacology. 48, 4, p. 664-670 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Three weeks of SSRI administration enhances the visual perceptual threshold: a randomized placebo-controlled study

    Lansner, Jon, Jensen, C. G., Petersen, Anders, Fisher, Patrick Mac Donald, Frøkjær, Vibe Gedsø, Vangkilde, Signe & Knudsen, Gitte Moos, 2019, In: Psychopharmacology. 236, 6, p. 1759–1769

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Transcranial Doppler is valid for determination of the lower limit of cerebral blood flow autoregulation

    Larsen, F. S., Olsen, K. S., Hansen, B. A., Paulson, Olaf B. & Knudsen, Gitte Moos, Oct 1994, In: Stroke. 25, 10, p. 1985-8 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Transcranial Doppler is valid for determination of the lower limit of cerebral blood flow autoregulation

    Larsen, F. S., Olsen, K. S., Hansen, B. A., Paulson, Olaf B. & Knudsen, Gitte Moos, Oct 1994, In: Stroke. 25, 10, p. 1985-8 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Cerebral blood flow autoregulation and transcranial Doppler sonography in patients with cirrhosis

    Larsen, F. S., Olsen, K. S., Ejlersen, E., Hansen, B. A., Paulson, Olaf B. & Knudsen, Gitte Moos, Sep 1995, In: Hepatology. 22, 3, p. 730-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Dissociated cerebral vasoparalysis in acute liver failure. A hypothesis of gradual cerebral hyperaemia

    Larsen, F. S., Adel Hansen, B., Pott, Frank Christian, Ejlersen, E., Secher, Niels H., Paulson, Olaf B. & Knudsen, Gitte Moos, Aug 1996, In: Journal of Hepatology. 25, 2, p. 145-51 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Cerebral blood flow autoregulation is absent in rats with thioacetamide-induced hepatic failure

    Larsen, F. S., Knudsen, Gitte Moos, Paulson, Olaf B. & Vilstrup, H., Oct 1994, In: Journal of Hepatology. 21, 4, p. 491-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Personality Traits in Huntington's Disease: An Exploratory Study of Gene Expansion Carriers and Non-Carriers

    Larsen, I. U., Mortensen, Erik Lykke, Vinther-Jensen, T., Nielsen, Jørgen Erik, Knudsen, Gitte Moos & Vogel, Asmus, Dec 2016, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 171, 8, p. 1153-1160 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    NREM sleep upregulates human brain pulsation detected by Ultrafast Magnetic Resonance Encephalography

    Larsen, S. M. U., Holst, S. C., Olsen, A. S., Zilstorff, D. B., Pleinert, S., Kiviniemi, V., Jennum, Poul, Nedergaard, Maiken & Knudsen, Gitte Moos, 2021, In: European Neuropsychopharmacology. 53, p. S361-S362 3 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  15. Published

    Genetic haplotype of the glymphatic-associated water channel aquaporin 4 modulates slow waves in human non-rapid eye movement sleep

    Larsen, S. M. U., Landolt, H. P., Berger, W., Nedergaard, Maiken, Knudsen, Gitte Moos & Holst, S. C., 2019, In: European Neuropsychopharmacology. 29, Supplement 6, p. S563-S564 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  16. Published

    Oral contraceptives and the serotonin 4 receptor in major depressive disorder: results from the NeuroPharm 1 study

    Larsen, S. V., Kohler-Forsberg, K., Poulsen, A. S., Dam, V. H., Ozenne, Brice Maxime Hugues, Svarer, C., Jorgensen, M. B., Knudsen, Gitte Moos & Frøkjær, Vibe Gedsø, 2021, In: European Neuropsychopharmacology. 53, p. S506-S507 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  17. Published

    Oral contraceptives and the serotonin 4 receptor: a molecular brain imaging study in healthy women

    Larsen, S. V., Köhler-Forsberg, K., Dam, V. H., Poulsen, A. S., Svarer, C., Jensen, P. S., Knudsen, Gitte Moos, Fisher, P. M., Ozenne, Brice Maxime Hugues & Frøkjær, Vibe Gedsø, 2020, In: Acta Psychiatrica Scandinavica. 142, 4, p. 294-306 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Healthy women who use oral contraceptives show lower brain serotonin 4 receptor binding relative to nonusers

    Larsen, S. V., Köhler-Forsberg, K. L., Dam, V. H., Poulsen, A. S., Ozenne, Brice Maxime Hugues, Svarer, C., Jensen, P. S., Knudsen, Gitte Moos & Frøkjær, Vibe Gedsø, 2019, In: European Neuropsychopharmacology. 29, Supplement 6, p. S215 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  19. Published

    Healthy women who use oral contraceptives show lower brain serotonin 4 receptor binding relative to non-users

    Larsen, S. V., Kohler-Forsberg, K. L., Dam, V. H., Poulsen, A. S., Ozenne, Brice Maxime Hugues, Svarer, C., Jensen, P. S., Knudsen, Gitte Moos & Frokjaer, V. G., 2019, In: Journal of Cerebral Blood Flow and Metabolism. 39, p. 539 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  20. Published

    Haplotype of the astrocytic water channel AQP4 is associated with slow wave energy regulation in human NREM sleep

    Larsen, S. M. U., Landolt, H. P., Berger, W., Nedergaard, Maiken, Knudsen, Gitte Moos & Holst, S. C., May 2020, In: PLOS Biology. 18, 5, 14 p., e3000623.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The Impact of Hormonal Contraceptive Use on Serotonergic Neurotransmission and Antidepressant Treatment Response: Results From the NeuroPharm 1 Study

    Larsen, S. V., Ozenne, Brice Maxime Hugues, Kohler-Forsberg, K., Poulsen, A. S., Dam, Vibeke Høyrup, Svarer, C., Knudsen, Gitte Moos, Jørgensen, Martin Balslev & Frøkjær, Vibe Gedsø, 2022, In: Frontiers in Endocrinology. 13, 12 p., 799675.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Nondisplaceable Binding Is a Potential Confounding Factor in 11C-PBR28 Translocator Protein PET Studies

    Karolinska Schizophrenia Project Consortium, K. S. P. C., 1 Mar 2021, In: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 62, 3, p. 412-417 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Kinetic models for estimating occupancy from single-scan PET displacement studies

    Laurell, G. L., Plavén-Sigray, P., Johansen, A., Raval, N. R., Nasser, A., Madsen, Clara Marianne Aabye, Madsen, J., Hansen, H. D., Donovan, L. L., Knudsen, Gitte Moos, Lammertsma, A. A., Ogden, R. T., Svarer, C. & Schain, M., 2023, In: Journal of Cerebral Blood Flow and Metabolism. 43, 9, p. 1544-1556 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Designing drug occupancy studies with PET neuroimaging: Sample size, occupancy ranges and analytical methods

    Laurell, G. L., Plavén-Sigray, P., Svarer, C., Ogden, R. T., Knudsen, Gitte Moos & Schain, M., 2022, In: NeuroImage. 263, 8 p., 119620.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Serotonergic neurotransmission in emotional processing: New evidence from long-term recreational poly-drug ecstasy use

    Laursen, H. R., Henningsson, S., Macoveanu, J., Jernigan, T. L., Siebner, Hartwig Roman, Holst, K. K., Skimminge, A. J. M., Knudsen, Gitte Moos, Ramsoy, T. Z. & Erritzøe, D., 2016, In: Journal of Psychopharmacology. 30, 12, p. 1296-1304 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Serotonin transporter gene (SLC6A4) variation and sensory processing sensitivity—Comparison with other anxiety-related temperamental dimensions

    Licht, C. L., Mortensen, Erik Lykke, Hjordt, L. V., Stenbæk, Dea Siggaard, Arentzen, T. E., Nørremølle, Anne & Knudsen, Gitte Moos, 2020, In: Molecular Genetics and Genomic Medicine. 8, 8, 10 p., e1352.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Changes in 5-HT4 receptor and 5-HT transporter binding in olfactory bulbectomized and glucocorticoid receptor heterozygous mice

    Licht, C. L., Kirkegaard, L., Zueger, M., Chourbaji, S., Gass, P., Aznar, S. & Knudsen, Gitte Moos, 1 Mar 2010, In: Neurochemistry International. 56, 4, p. 603-10 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Effects of the 5-HT(4) receptor agonist RS67333 and paroxetine on hippocampal extracellular 5-HT levels

    Licht, C. L., Knudsen, Gitte Moos & Sharp, T., 31 May 2010, In: Neuroscience Letters. 476, 2, p. 58-61 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Cluster analysis in kinetic modelling of the brain: a noninvasive alternative to arterial sampling

    Liptrot, M., Adams, K. H., Martiny, L., Pinborg, Lars Hageman, Lonsdale, M. N., Olsen, N. V., Holm, S., Svarer, C. & Knudsen, Gitte Moos, 2004, In: NeuroImage. 21, 2, p. 483-493 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    A non-synonymous polymorphism in galactose mutarotase (GALM) is associated with serotonin transporter binding potential in the human thalamus: results of a genome-wide association study

    Liu, X., Cannon, D. M., Akula, N., Moya, P. R., Knudsen, Gitte Moos, Arentzen, T., Steele, J., Laje, G., Drevets, W. C. & McMahon, F. J., 2011, In: Molecular Psychiatry. 16, 6, p. 584-5 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Pretargeted Imaging beyond the Blood–Brain Barrier: Utopia or Feasible?

    Lopes van den Broek, S., Shalgunov, Vladimir, García Vázquez, R., Beschorner, Natalie, Bidesi, N. S. R., Nedergaard, Maiken, Knudsen, Gitte Moos, Sehlin, D., Syvänen, S. & Herth, Matthias Manfred, 2022, In: Pharmaceuticals. 15, 10, 13 p., 1191.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    The Alzheimer's disease 5xFAD mouse model is best suited to investigate pretargeted imaging approaches beyond the blood-brain barrier

    Lopes van den Broek, S. I., Sehlin, D., Andersen, Jens Velde, Aldana, Blanca, Beschorner, Natalie, Nedergaard, Maiken, Knudsen, Gitte Moos, Syvanen, S. & Herth, Matthias Manfred, 2023, In: Frontiers in Nuclear Medicine. 2, 7 p., 1001722.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Comparable roles for serotonin in rats and humans for computations underlying flexible decision-making

    Luo, Q., Kanen, J. W., Bari, A., Skandali, N., Langley, C., Knudsen, Gitte Moos, Alsiö, J., Phillips, B. U., Sahakian, B. J., Cardinal, R. N. & Robbins, T. W., 2024, In: Neuropsychopharmacology. 49, 3, p. 600-608 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Radiolabeling and in vivo evaluation of [11C]AGH-44: a potential lead structure to develop a positron emission tomography radioligand for the 5-HT7 receptor

    L’Estrade, E. T., Petersen, I. N., Xiong, M., Hogendorf, A. S., Hogendorf, A., Kristensen, Jesper Langgaard, Kjær, Andreas, Bojarski, A. J., Erlandsson, M., Ohlsson, T., Knudsen, Gitte Moos & Herth, Matthias Manfred, 1 Nov 2019, In: Journal of Radioanalytical and Nuclear Chemistry. 322, 2, p. 847-851 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Effect of graded hyperventilation on cerebral metabolism in a cisterna magna blood injection model of subarachnoid hemorrhage in rats

    Ma, X., Bay-Hansen, R., Hauerberg, J., Knudsen, Gitte Moos, Olsen, N. V. & Juhler, Marianne, 2006, In: Journal of Neurosurgical Anesthesiology. 18, 1, p. 18-23 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Serotonin is involved in processing negative outcomes caused by low-risk decisions

    Macoveanu, J., Rowe, J. B., Hornboll, B., Knudsen, Gitte Moos, Paulson, O. B. & Siebner, H. R., 2011. 0 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  37. Published

    Trajectory of aberrant reward processing in patients with bipolar disorder – A longitudinal fMRI study

    Macoveanu, J., Stougaard, M. E., Kjærstad, H. L., Knudsen, Gitte Moos, Vinberg, Maj, Kessing, Lars Vedel & Miskowiak, Kamilla, 2022, In: Journal of Affective Disorders. 312, p. 235-244 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Effects of erythropoietin on cognitive impairment and prefrontal cortex activity across affective disorders: A randomized, double-blinded, placebo-controlled trial

    Macoveanu, J., Petersen, J. Z., Mariegaard, Johanna, Jespersen, Andreas Elleby, Cramer, Katrine, Bruun, C. F., Madsen, H. Ø., Jørgensen, Martin Balslev, Vinberg, Maj, Fisher, Patrick Mac Donald, Knudsen, Gitte Moos, Hageman, Ida, Ehrenreich, H., Kessing, Lars Vedel & Miskowiak, Kamilla, 2024, In: Journal of Psychopharmacology. 38, 4, p. 362-374

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Neural basis of memory impairments and relation to functional disability in fully or partially remitted patients with affective disorders

    Macoveanu, Julian, Mariegaard, Johanna, Petersen, J. Z., Fisher, P. M., Vinberg, Maj, Jørgensen, Martin Balslev, Knudsen, Gitte Moos, Kessing, Lars Vedel & Miskowiak, Kamilla, 2023, In: Progress in Neuro-Psychopharmacology and Biological Psychiatry. 125, 110767.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Structural brain abnormalities associated with cognitive impairments in bipolar disorder

    Macoveanu, J., Freeman, K. O., Kjærstad, H. L., Knudsen, Gitte Moos, Kessing, Lars Vedel & Miskowiak, Kamilla, 2021, In: Acta Psychiatrica Scandinavica. 144, 4, p. 379-391 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Bright-light intervention induces a dose-dependent increase in striatal response to risk in healthy volunteers

    Macoveanu, J., Fisher, P. M., Madsen, M. K., Mc Mahon, B., Knudsen, Gitte Moos & Siebner, Hartwig Roman, 2016, In: NeuroImage. 139, p. 37-43 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Abnormal prefrontal cortex processing of reward prediction errors in recently diagnosed patients with bipolar disorder and their unaffected relatives

    Macoveanu, J., Kjærstad, H. L., Chase, H. W., Frangou, S., Knudsen, Gitte Moos, Vinberg, Maj, Kessing, Lars Vedel & Miskowiak, Kamilla, Dec 2020, In: Bipolar Disorders. 22, 8, p. 849-859 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Accepted/In press

    Longitudinal changes in resting-state functional connectivity as markers of vulnerability or resilience in first-degree relatives of patients with bipolar disorder

    Macoveanu, J., Fortea, L., Kjærstad, H. L., Coello, K., Faurholt-Jepsen, Maria , Fisher, Patrick Mac Donald, Knudsen, Gitte Moos, Radua, J., Vieta, E., Frangou, S., Vinberg, Maj, Kessing, Lars Vedel & Miskowiak, Kamilla, 2024, (Accepted/In press) In: Psychological Medicine.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Associations between aberrant working memory-related neural activity and cognitive impairments in somatically healthy, remitted patients with mood disorders

    Macoveanu, J., Petersen, J. Z., Fisher, P. M., Kessing, Lars Vedel, Knudsen, Gitte Moos & Miskowiak, Kamilla, 2023, In: Psychological Medicine. 53, 15, 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Early longitudinal changes in brain structure and cognitive functioning in remitted patients with recently diagnosed bipolar disorder

    Macoveanu, J., Damgaard, Viktoria, Ysbæk-Nielsen, Alexander Tobias, Frangou, S., Yatham, L. N., Chakrabarty, T., Stougaard, M. E., Knudsen, Gitte Moos, Vinberg, Maj, Kessing, Lars Vedel, Kjærstad, H. L. & Miskowiak, Kamilla, 2023, In: Journal of Affective Disorders. 339, p. 153-161 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Action-based cognitive remediation in bipolar disorder improved verbal memory but had no effect on the neural response during episodic memory encoding

    Macoveanu, J., Damgaard, Viktoria, Ott, C. V., Knudsen, Gitte Moos, Kessing, Lars Vedel & Miskowiak, Kamilla, 2022, In: Psychiatry Research - Neuroimaging. 319, 111418.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Playing it safe but losing anyway-Serotonergic signaling of negative outcomes in dorsomedial prefrontal cortex in the context of risk-aversion

    Macoveanu, J., Rowe, J. B., Hornboll, B., Elliott, R., Paulson, Olaf B., Knudsen, Gitte Moos & Siebner, Hartwig Roman, 23 Aug 2013, In: European Neuropsychopharmacology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Affective episodes in recently diagnosed patients with bipolar disorder associated with altered working memory-related prefrontal cortex activity: A longitudinal fMRI study

    Macoveanu, J., Kjærstad, H. L., Vinberg, Maj, Harmer, C., Fisher, P. M. D., Knudsen, Gitte Moos, Kessing, Lars Vedel & Miskowiak, Kamilla, 2021, In: Journal of Affective Disorders. 295, p. 647-656 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Synthesis and Biological Evaluation of 125I/123I-Labelled Analogues of Citalopram and Escitalopram as Potential Radioligands for Imaging of the Serotonin Transporter

    Madsen, J., Elfving, B., Frøkjær, V., Kornum, B. R., Thomsen, G., Martiny, L. & Knudsen, Gitte Moos, 2011, In: Journal of Labelled Compounds and Radiopharmaceuticals. 54, p. 185-190 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Lack of association between prior depressive episodes and cerebral [(11)C]PiB binding

    Madsen, K., Hasselbalch, B. J., Frederiksen, K. S., Haahr, M. E., Gade, A., Law, I., Price, J. C., Knudsen, Gitte Moos, Kessing, Lars Vedel & Hasselbalch, Steen, 2012, In: Neurobiology of Aging. 33, 12, p. 2334-2342

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 6065