Gitte Moos Knudsen
Clinical Professor
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Predicting Treatment Outcome in Major Depressive Disorder Using Serotonin 4 Receptor PET Brain Imaging, Functional MRI, Cognitive-, EEG-Based, and Peripheral Biomarkers: A NeuroPharm Open Label Clinical Trial Protocol
Köhler-Forsberg, K., Jørgensen, Anders, Dam, V. H., Stenbæk, Dea Siggaard, Fisher, P. M., Ip, C. T., Ganz, Melanie, Poulsen, Henrik Enghusen, Giraldi, Annamaria Giovanna Elena, Ozenne, Brice Maxime Hugues, Jørgensen, Martin Balslev, Knudsen, Gitte Moos & Frøkjær, Vibe Gedsø, 2020, In: Frontiers in Psychiatry. 11, 15 p., 641.Research output: Contribution to journal › Journal article › Research › peer-review
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Radiosynthesis and preclinical evaluation of [11 C]Cimbi-701 - Towards the imaging of cerebral 5-HT7 receptors
L 'Estrade, E. T., Shalgunov, Vladimir, Edgar, F. G., Strebl-Bantillo, M. G., Xiong, M., Crestey, F., Neelamegam, R., Dyssegaard, A., Lehel, S., Erlandsson, M., Ohlsson, T., Hooker, J. M., Knudsen, Gitte Moos, Herth, Matthias Manfred & Hansen, H. D., 2020, In: Journal of Labelled Compounds and Radiopharmaceuticals. 63, p. 46-55Research output: Contribution to journal › Journal article › Research › peer-review
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Towards selective CNS PET Imaging of the 5-HT7 Receptor System: Past, Present and Future
L'Estrade, E. T., Erlandsson, M., Edgar, F. G., Ohlsson, T., Knudsen, Gitte Moos & Herth, Matthias Manfred, 2020, In: Neuropharmacology. 172, 107830.Research output: Contribution to journal › Review › Research › peer-review
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Synthesis and Pharmacological Evaluation of [C-11]4-Methoxy-N-[2-(thiophen-2-yl) imidazo[1,2-a] pyridin-3-yl]benzamide as a Brain Penetrant PET Ligand Selective for the delta-Subunit-Containing gamma-Aminobutyric Acid Type A Receptors
L'Estrade, E. T., Hansen, H. D., Falk-Petersen, C., Haugaard, A., Griem-Krey, Nane, Jung, S., Lueddens, H., Schirmeister, T., Erlandsson, M., Ohlsson, T., Knudsen, Gitte Moos, Herth, Matthias Manfred, Wellendorph, Petrine & Frølund, Bente, May 2019, In: ACS Omega. 4, 5, p. 8846-8851Research output: Contribution to journal › Journal article › Research › peer-review
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PET radiotracer translation from rats to higher species, using an increased-throughput in vivo evaluation strategy
L'Estrade, E. T., Xiong, M., Petersen, I., Shalgunov, Vladimir, Edgar, F. G., Hansen, H., Erlandsson, M., Ohlsson, T., Knudsen, Gitte Moos, Palner, M. & Herth, Matthias Manfred, May 2019, p. S389-S390.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Chronic escitalopram in healthy volunteers has specific effects on reinforcement sensitivity: a double-blind, placebo-controlled semi-randomised study
Langley, C., Armand, Sophia, Luo, Q., Savulich, G., Segerberg, T., Søndergaard, A., Pedersen, E. B., Svart, N., Overgaard-Hansen, O., Johansen, A., Borgsted, C., Cardinal, R. N., Robbins, T. W., Stenbæk, Dea Siggaard, Knudsen, Gitte Moos & Sahakian, B. J., 2023, In: Neuropsychopharmacology. 48, 4, p. 664-670 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Three weeks of SSRI administration enhances the visual perceptual threshold: a randomized placebo-controlled study
Lansner, Jon, Jensen, C. G., Petersen, Anders, Fisher, Patrick Mac Donald, Frøkjær, Vibe Gedsø, Vangkilde, Signe & Knudsen, Gitte Moos, 2019, In: Psychopharmacology. 236, 6, p. 1759–1769Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcranial Doppler is valid for determination of the lower limit of cerebral blood flow autoregulation
Larsen, F. S., Olsen, K. S., Hansen, B. A., Paulson, Olaf B. & Knudsen, Gitte Moos, Oct 1994, In: Stroke. 25, 10, p. 1985-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcranial Doppler is valid for determination of the lower limit of cerebral blood flow autoregulation
Larsen, F. S., Olsen, K. S., Hansen, B. A., Paulson, Olaf B. & Knudsen, Gitte Moos, Oct 1994, In: Stroke. 25, 10, p. 1985-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cerebral blood flow autoregulation and transcranial Doppler sonography in patients with cirrhosis
Larsen, F. S., Olsen, K. S., Ejlersen, E., Hansen, B. A., Paulson, Olaf B. & Knudsen, Gitte Moos, Sep 1995, In: Hepatology. 22, 3, p. 730-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dissociated cerebral vasoparalysis in acute liver failure. A hypothesis of gradual cerebral hyperaemia
Larsen, F. S., Adel Hansen, B., Pott, Frank Christian, Ejlersen, E., Secher, Niels H., Paulson, Olaf B. & Knudsen, Gitte Moos, Aug 1996, In: Journal of Hepatology. 25, 2, p. 145-51 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cerebral blood flow autoregulation is absent in rats with thioacetamide-induced hepatic failure
Larsen, F. S., Knudsen, Gitte Moos, Paulson, Olaf B. & Vilstrup, H., Oct 1994, In: Journal of Hepatology. 21, 4, p. 491-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Personality Traits in Huntington's Disease: An Exploratory Study of Gene Expansion Carriers and Non-Carriers
Larsen, I. U., Mortensen, Erik Lykke, Vinther-Jensen, T., Nielsen, Jørgen Erik, Knudsen, Gitte Moos & Vogel, Asmus, Dec 2016, In: American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 171, 8, p. 1153-1160 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NREM sleep upregulates human brain pulsation detected by Ultrafast Magnetic Resonance Encephalography
Larsen, S. M. U., Holst, S. C., Olsen, A. S., Zilstorff, D. B., Pleinert, S., Kiviniemi, V., Jennum, Poul, Nedergaard, Maiken & Knudsen, Gitte Moos, 2021, In: European Neuropsychopharmacology. 53, p. S361-S362 3 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Genetic haplotype of the glymphatic-associated water channel aquaporin 4 modulates slow waves in human non-rapid eye movement sleep
Larsen, S. M. U., Landolt, H. P., Berger, W., Nedergaard, Maiken, Knudsen, Gitte Moos & Holst, S. C., 2019, In: European Neuropsychopharmacology. 29, Supplement 6, p. S563-S564 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Oral contraceptives and the serotonin 4 receptor in major depressive disorder: results from the NeuroPharm 1 study
Larsen, S. V., Kohler-Forsberg, K., Poulsen, A. S., Dam, V. H., Ozenne, Brice Maxime Hugues, Svarer, C., Jorgensen, M. B., Knudsen, Gitte Moos & Frøkjær, Vibe Gedsø, 2021, In: European Neuropsychopharmacology. 53, p. S506-S507 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Oral contraceptives and the serotonin 4 receptor: a molecular brain imaging study in healthy women
Larsen, S. V., Köhler-Forsberg, K., Dam, V. H., Poulsen, A. S., Svarer, C., Jensen, P. S., Knudsen, Gitte Moos, Fisher, P. M., Ozenne, Brice Maxime Hugues & Frøkjær, Vibe Gedsø, 2020, In: Acta Psychiatrica Scandinavica. 142, 4, p. 294-306 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Healthy women who use oral contraceptives show lower brain serotonin 4 receptor binding relative to nonusers
Larsen, S. V., Köhler-Forsberg, K. L., Dam, V. H., Poulsen, A. S., Ozenne, Brice Maxime Hugues, Svarer, C., Jensen, P. S., Knudsen, Gitte Moos & Frøkjær, Vibe Gedsø, 2019, In: European Neuropsychopharmacology. 29, Supplement 6, p. S215 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Healthy women who use oral contraceptives show lower brain serotonin 4 receptor binding relative to non-users
Larsen, S. V., Kohler-Forsberg, K. L., Dam, V. H., Poulsen, A. S., Ozenne, Brice Maxime Hugues, Svarer, C., Jensen, P. S., Knudsen, Gitte Moos & Frokjaer, V. G., 2019, In: Journal of Cerebral Blood Flow and Metabolism. 39, p. 539 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Haplotype of the astrocytic water channel AQP4 is associated with slow wave energy regulation in human NREM sleep
Larsen, S. M. U., Landolt, H. P., Berger, W., Nedergaard, Maiken, Knudsen, Gitte Moos & Holst, S. C., May 2020, In: PLOS Biology. 18, 5, 14 p., e3000623.Research output: Contribution to journal › Journal article › Research › peer-review
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The Impact of Hormonal Contraceptive Use on Serotonergic Neurotransmission and Antidepressant Treatment Response: Results From the NeuroPharm 1 Study
Larsen, S. V., Ozenne, Brice Maxime Hugues, Kohler-Forsberg, K., Poulsen, A. S., Dam, Vibeke Høyrup, Svarer, C., Knudsen, Gitte Moos, Jørgensen, Martin Balslev & Frøkjær, Vibe Gedsø, 2022, In: Frontiers in Endocrinology. 13, 12 p., 799675.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nondisplaceable Binding Is a Potential Confounding Factor in 11C-PBR28 Translocator Protein PET Studies
Karolinska Schizophrenia Project Consortium, K. S. P. C., 1 Mar 2021, In: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 62, 3, p. 412-417 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Kinetic models for estimating occupancy from single-scan PET displacement studies
Laurell, G. L., Plavén-Sigray, P., Johansen, A., Raval, N. R., Nasser, A., Madsen, Clara Marianne Aabye, Madsen, J., Hansen, H. D., Donovan, L. L., Knudsen, Gitte Moos, Lammertsma, A. A., Ogden, R. T., Svarer, C. & Schain, M., 2023, In: Journal of Cerebral Blood Flow and Metabolism. 43, 9, p. 1544-1556 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Designing drug occupancy studies with PET neuroimaging: Sample size, occupancy ranges and analytical methods
Laurell, G. L., Plavén-Sigray, P., Svarer, C., Ogden, R. T., Knudsen, Gitte Moos & Schain, M., 2022, In: NeuroImage. 263, 8 p., 119620.Research output: Contribution to journal › Journal article › Research › peer-review
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Serotonergic neurotransmission in emotional processing: New evidence from long-term recreational poly-drug ecstasy use
Laursen, H. R., Henningsson, S., Macoveanu, J., Jernigan, T. L., Siebner, Hartwig Roman, Holst, K. K., Skimminge, A. J. M., Knudsen, Gitte Moos, Ramsoy, T. Z. & Erritzøe, D., 2016, In: Journal of Psychopharmacology. 30, 12, p. 1296-1304 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Serotonin transporter gene (SLC6A4) variation and sensory processing sensitivity—Comparison with other anxiety-related temperamental dimensions
Licht, C. L., Mortensen, Erik Lykke, Hjordt, L. V., Stenbæk, Dea Siggaard, Arentzen, T. E., Nørremølle, Anne & Knudsen, Gitte Moos, 2020, In: Molecular Genetics and Genomic Medicine. 8, 8, 10 p., e1352.Research output: Contribution to journal › Journal article › Research › peer-review
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Changes in 5-HT4 receptor and 5-HT transporter binding in olfactory bulbectomized and glucocorticoid receptor heterozygous mice
Licht, C. L., Kirkegaard, L., Zueger, M., Chourbaji, S., Gass, P., Aznar, S. & Knudsen, Gitte Moos, 1 Mar 2010, In: Neurochemistry International. 56, 4, p. 603-10 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of the 5-HT(4) receptor agonist RS67333 and paroxetine on hippocampal extracellular 5-HT levels
Licht, C. L., Knudsen, Gitte Moos & Sharp, T., 31 May 2010, In: Neuroscience Letters. 476, 2, p. 58-61 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
Cluster analysis in kinetic modelling of the brain: a noninvasive alternative to arterial sampling
Liptrot, M., Adams, K. H., Martiny, L., Pinborg, Lars Hageman, Lonsdale, M. N., Olsen, N. V., Holm, S., Svarer, C. & Knudsen, Gitte Moos, 2004, In: NeuroImage. 21, 2, p. 483-493 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A non-synonymous polymorphism in galactose mutarotase (GALM) is associated with serotonin transporter binding potential in the human thalamus: results of a genome-wide association study
Liu, X., Cannon, D. M., Akula, N., Moya, P. R., Knudsen, Gitte Moos, Arentzen, T., Steele, J., Laje, G., Drevets, W. C. & McMahon, F. J., 2011, In: Molecular Psychiatry. 16, 6, p. 584-5 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pretargeted Imaging beyond the Blood–Brain Barrier: Utopia or Feasible?
Lopes van den Broek, S., Shalgunov, Vladimir, García Vázquez, R., Beschorner, Natalie, Bidesi, N. S. R., Nedergaard, Maiken, Knudsen, Gitte Moos, Sehlin, D., Syvänen, S. & Herth, Matthias Manfred, 2022, In: Pharmaceuticals. 15, 10, 13 p., 1191.Research output: Contribution to journal › Journal article › Research › peer-review
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The Alzheimer's disease 5xFAD mouse model is best suited to investigate pretargeted imaging approaches beyond the blood-brain barrier
Lopes van den Broek, S. I., Sehlin, D., Andersen, Jens Velde, Aldana, Blanca, Beschorner, Natalie, Nedergaard, Maiken, Knudsen, Gitte Moos, Syvanen, S. & Herth, Matthias Manfred, 2023, In: Frontiers in Nuclear Medicine. 2, 7 p., 1001722.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparable roles for serotonin in rats and humans for computations underlying flexible decision-making
Luo, Q., Kanen, J. W., Bari, A., Skandali, N., Langley, C., Knudsen, Gitte Moos, Alsiö, J., Phillips, B. U., Sahakian, B. J., Cardinal, R. N. & Robbins, T. W., 2024, In: Neuropsychopharmacology. 49, 3, p. 600-608 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Radiolabeling and in vivo evaluation of [11C]AGH-44: a potential lead structure to develop a positron emission tomography radioligand for the 5-HT7 receptor
L’Estrade, E. T., Petersen, I. N., Xiong, M., Hogendorf, A. S., Hogendorf, A., Kristensen, Jesper Langgaard, Kjær, Andreas, Bojarski, A. J., Erlandsson, M., Ohlsson, T., Knudsen, Gitte Moos & Herth, Matthias Manfred, 1 Nov 2019, In: Journal of Radioanalytical and Nuclear Chemistry. 322, 2, p. 847-851 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of graded hyperventilation on cerebral metabolism in a cisterna magna blood injection model of subarachnoid hemorrhage in rats
Ma, X., Bay-Hansen, R., Hauerberg, J., Knudsen, Gitte Moos, Olsen, N. V. & Juhler, Marianne, 2006, In: Journal of Neurosurgical Anesthesiology. 18, 1, p. 18-23 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Serotonin is involved in processing negative outcomes caused by low-risk decisions
Macoveanu, J., Rowe, J. B., Hornboll, B., Knudsen, Gitte Moos, Paulson, O. B. & Siebner, H. R., 2011. 0 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Trajectory of aberrant reward processing in patients with bipolar disorder – A longitudinal fMRI study
Macoveanu, J., Stougaard, M. E., Kjærstad, H. L., Knudsen, Gitte Moos, Vinberg, Maj, Kessing, Lars Vedel & Miskowiak, Kamilla, 2022, In: Journal of Affective Disorders. 312, p. 235-244 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of erythropoietin on cognitive impairment and prefrontal cortex activity across affective disorders: A randomized, double-blinded, placebo-controlled trial
Macoveanu, J., Petersen, J. Z., Mariegaard, Johanna, Jespersen, Andreas Elleby, Cramer, Katrine, Bruun, C. F., Madsen, H. Ø., Jørgensen, Martin Balslev, Vinberg, Maj, Fisher, Patrick Mac Donald, Knudsen, Gitte Moos, Hageman, Ida, Ehrenreich, H., Kessing, Lars Vedel & Miskowiak, Kamilla, 2024, In: Journal of Psychopharmacology. 38, 4, p. 362-374Research output: Contribution to journal › Journal article › Research › peer-review
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Neural basis of memory impairments and relation to functional disability in fully or partially remitted patients with affective disorders
Macoveanu, Julian, Mariegaard, Johanna, Petersen, J. Z., Fisher, P. M., Vinberg, Maj, Jørgensen, Martin Balslev, Knudsen, Gitte Moos, Kessing, Lars Vedel & Miskowiak, Kamilla, 2023, In: Progress in Neuro-Psychopharmacology and Biological Psychiatry. 125, 110767.Research output: Contribution to journal › Journal article › Research › peer-review
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Structural brain abnormalities associated with cognitive impairments in bipolar disorder
Macoveanu, J., Freeman, K. O., Kjærstad, H. L., Knudsen, Gitte Moos, Kessing, Lars Vedel & Miskowiak, Kamilla, 2021, In: Acta Psychiatrica Scandinavica. 144, 4, p. 379-391 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bright-light intervention induces a dose-dependent increase in striatal response to risk in healthy volunteers
Macoveanu, J., Fisher, P. M., Madsen, M. K., Mc Mahon, B., Knudsen, Gitte Moos & Siebner, Hartwig Roman, 2016, In: NeuroImage. 139, p. 37-43 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Abnormal prefrontal cortex processing of reward prediction errors in recently diagnosed patients with bipolar disorder and their unaffected relatives
Macoveanu, J., Kjærstad, H. L., Chase, H. W., Frangou, S., Knudsen, Gitte Moos, Vinberg, Maj, Kessing, Lars Vedel & Miskowiak, Kamilla, Dec 2020, In: Bipolar Disorders. 22, 8, p. 849-859 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Accepted/In press
Longitudinal changes in resting-state functional connectivity as markers of vulnerability or resilience in first-degree relatives of patients with bipolar disorder
Macoveanu, J., Fortea, L., Kjærstad, H. L., Coello, K., Faurholt-Jepsen, Maria , Fisher, Patrick Mac Donald, Knudsen, Gitte Moos, Radua, J., Vieta, E., Frangou, S., Vinberg, Maj, Kessing, Lars Vedel & Miskowiak, Kamilla, 2024, (Accepted/In press) In: Psychological Medicine.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Associations between aberrant working memory-related neural activity and cognitive impairments in somatically healthy, remitted patients with mood disorders
Macoveanu, J., Petersen, J. Z., Fisher, P. M., Kessing, Lars Vedel, Knudsen, Gitte Moos & Miskowiak, Kamilla, 2023, In: Psychological Medicine. 53, 15, 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Early longitudinal changes in brain structure and cognitive functioning in remitted patients with recently diagnosed bipolar disorder
Macoveanu, J., Damgaard, Viktoria, Ysbæk-Nielsen, Alexander Tobias, Frangou, S., Yatham, L. N., Chakrabarty, T., Stougaard, M. E., Knudsen, Gitte Moos, Vinberg, Maj, Kessing, Lars Vedel, Kjærstad, H. L. & Miskowiak, Kamilla, 2023, In: Journal of Affective Disorders. 339, p. 153-161 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Action-based cognitive remediation in bipolar disorder improved verbal memory but had no effect on the neural response during episodic memory encoding
Macoveanu, J., Damgaard, Viktoria, Ott, C. V., Knudsen, Gitte Moos, Kessing, Lars Vedel & Miskowiak, Kamilla, 2022, In: Psychiatry Research - Neuroimaging. 319, 111418.Research output: Contribution to journal › Journal article › Research › peer-review
Playing it safe but losing anyway-Serotonergic signaling of negative outcomes in dorsomedial prefrontal cortex in the context of risk-aversion
Macoveanu, J., Rowe, J. B., Hornboll, B., Elliott, R., Paulson, Olaf B., Knudsen, Gitte Moos & Siebner, Hartwig Roman, 23 Aug 2013, In: European Neuropsychopharmacology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Affective episodes in recently diagnosed patients with bipolar disorder associated with altered working memory-related prefrontal cortex activity: A longitudinal fMRI study
Macoveanu, J., Kjærstad, H. L., Vinberg, Maj, Harmer, C., Fisher, P. M. D., Knudsen, Gitte Moos, Kessing, Lars Vedel & Miskowiak, Kamilla, 2021, In: Journal of Affective Disorders. 295, p. 647-656 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthesis and Biological Evaluation of 125I/123I-Labelled Analogues of Citalopram and Escitalopram as Potential Radioligands for Imaging of the Serotonin Transporter
Madsen, J., Elfving, B., Frøkjær, V., Kornum, B. R., Thomsen, G., Martiny, L. & Knudsen, Gitte Moos, 2011, In: Journal of Labelled Compounds and Radiopharmaceuticals. 54, p. 185-190 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lack of association between prior depressive episodes and cerebral [(11)C]PiB binding
Madsen, K., Hasselbalch, B. J., Frederiksen, K. S., Haahr, M. E., Gade, A., Law, I., Price, J. C., Knudsen, Gitte Moos, Kessing, Lars Vedel & Hasselbalch, Steen, 2012, In: Neurobiology of Aging. 33, 12, p. 2334-2342Research output: Contribution to journal › Journal article › Research › peer-review
ID: 6065
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Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression
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The Bipolar Illness Onset study: research protocol for the BIO cohort study
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Design of Infusion Schemes for Neuroreceptor Imaging: Application to [(11)C]Flumazenil-PET Steady-State Study
Research output: Contribution to journal › Journal article › Research › peer-review
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