Gitte Moos Knudsen
Clinical Professor
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Cerebral serotonin transporter measurements with [11C]DASB: A review on acquisition and preprocessing across 21 PET centres
Nørgaard, M., Ganz, Melanie, Svarer, C., Feng, L., Ichise, M., Lanzenberger, R., Lubberink, M., Parsey, R. V., Politis, M., Rabiner, E. A., Slifstein, M., Sossi, V., Suhara, T., Talbot, P. S., Turkheimer, F., Strother, S. C. & Knudsen, Gitte Moos, 2019, In: Journal of Cerebral Blood Flow and Metabolism. 39, 2, p. 210-222 13 p.Research output: Contribution to journal › Review › Research › peer-review
Brain Networks involved in Seasonal Affective Disorder: A Neuroimaging PET Study of 5-HTT Expression
Nørgaard, M. A., Svarer, C., Ganz, Melanie, McMahon, B., Fisher, P. M., Churchill, N. W., Beliveau, V., Grady, C. L., Strother, S. C. & Knudsen, Gitte Moos, 2017.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
Brain Networks Implicated in Seasonal Affective Disorder: A Neuroimaging PET Study of the Serotonin Transporter
Nørgaard, M. A., Ganz, Melanie, Svarer, C., Fisher, P. M., Churchill, N. W., Beliveau, V., Grady, C. L., Strother, S. C. & Knudsen, Gitte Moos, 3 Nov 2017, In: Frontiers in Neuroscience. 11, 614Research output: Contribution to journal › Journal article › Research › peer-review
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Psilocybin modulation of time-varying functional connectivity is associated with plasma psilocin and subjective effects
Olsen, A. S., Lykkebo-Valløe, A., Ozenne, Brice Maxime Hugues, Madsen, M. K., Stenbæk, Dea Siggaard, Armand, Sophia, Mørup, M., Ganz, Melanie, Knudsen, Gitte Moos & Fisher, P. M., 2022, In: NeuroImage. 264, 12 p., 119716.Research output: Contribution to journal › Journal article › Research › peer-review
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Change in prefrontal activity and executive functions after action-based cognitive remediation in bipolar disorder: a randomized controlled trial
Ott, C. V., Macoveanu, J., Bowie, C. R., Fisher, P. M., Knudsen, Gitte Moos, Kessing, Lars Vedel & Miskowiak, Kamilla, 2021, In: Neuropsychopharmacology. 46, p. 1113–1121Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of action-based cognitive remediation on cognition and neural activity in bipolar disorder: Study protocol for a randomized controlled trial
Ott, C. V., Vinberg, Maj, Bowie, C. R., Christensen, E. M., Knudsen, Gitte Moos, Kessing, Lars Vedel & Miskowiak, Kamilla, 12 Sep 2018, In: Trials. 19, 1, 10 p., 487.Research output: Contribution to journal › Journal article › Research › peer-review
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Correction to: Effect of action-based cognitive remediation on cognition and neural activity in bipolar disorder: study protocol for a randomized controlled trial
Ott, C. V., Vinberg, Maj, Bowie, C. R., Christensen, E. M., Knudsen, Gitte Moos, Kessing, Lars Vedel & Miskowiak, Kamilla, 8 Apr 2019, In: Trials. 20, 1, 201.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Effects of unilateral 6-OHDA lesions on [ <sup>3</sup>H]-N- propylnorapomorphine binding in striatum ex vivo and vulnerability to amphetamine-evoked dopamine release in rat
Palner, M., Kjærby, Celia, Knudsen, Gitte Moos & Cumming, P., 2011, In: Neurochemistry International.Research output: Contribution to journal › Journal article › Research › peer-review
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Radiosynthesis and ex vivo evaluation of (R)-(-)-2-chloro-N-[1-11C-propyl]n-propylnorapomorphine:
Palner, M., McCormick, P., Gillings, N., Begtrup, M., Wilson, A. A. & Knudsen, Gitte Moos, 2010, In: Nuclear Medicine and Biology. 37, 1, p. 35-40Research output: Contribution to journal › Journal article › Research › peer-review
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Radiosynthesis and ex vivo evaluation of (R)-(-)-2-chloro-N-[1-11C-propyl]n-propylnorapomorphine
Palner, M., McCormick, P., Gillings, N., Begtrup, M., Wilson, A. A. & Knudsen, Gitte Moos, 1 Jan 2010, In: Nuclear Medicine and Biology. 37, 1, p. 35-40 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Systemic catechol-O-methyl transferase inhibition enables the D1 agonist radiotracer R-[11C]SKF 82957
Palner, M., McCormick, P., Parkes, J., Knudsen, Gitte Moos & Wilson, A. A., 1 Oct 2010, In: Nuclear Medicine and Biology. 37, 7, p. 837-43 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ex vivo evaluation of the serotonin 1A receptor partial agonist [³H]CUMI-101 in awake rats
Palner, M., Underwood, M. D., Kumar, D. J. S., Arango, V., Knudsen, Gitte Moos, John Mann, J. & Parsey, R. V., 2011, In: Synapse. 65, 8, p. 715-23 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of unilateral 6-OHDA lesions on [3H]-N-propylnorapomorphine binding in striatum ex vivo and vulnerability to amphetamine-evoked dopamine release in rat
Palner, M., Kjaerby, C., Knudsen, Gitte Moos & Cumming, P., 2011, In: Neurochemistry International. 58, 3, p. 243-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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5-HT radioligands for human brain imaging with PET and SPECT
Paterson, L. M., Kornum, Birgitte Rahbek, Nutt, D. J., Pike, V. W. & Knudsen, Gitte Moos, Jan 2013, In: Medicinal Research Reviews. 33, 1, p. 54-111 58 p.Research output: Contribution to journal › Review › Research › peer-review
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Measuring endogenous 5-HT release by emission tomography: promises and pitfalls
Paterson, L. M., Tyacke, R. J., Nutt, D. J. & Knudsen, Gitte Moos, 1 Oct 2010, In: Journal of Cerebral Blood Flow and Metabolism. 30, 10, p. 1682-706 25 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Comments on Point:Counterpoint: Sympathetic activity does/does not influence cerebral blood flow. Role of a rudimentary sympathetic nervous system on cerebral blood flow
Paulson, Olaf B. & Knudsen, Gitte Moos, 2008, In: Journal of Applied Physiology. 105, 4, p. 1371-1372 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cerebral blood flow response to functional activation
Paulson, Olaf B., Hasselbalch, S. G., Rostrup, Egill, Knudsen, Gitte Moos, Pelligrino, D., Paulson, O. B., Hasselbalch, Steen, Rostrup, E., Knudsen, G. M. & Pelligrino, D., 1 Jan 2010, In: Journal of Cerebral Blood Flow and Metabolism. 30, 1, p. 2-14 13 p.Research output: Contribution to journal › Review › Research › peer-review
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Cerebral blood flow autoregulation in early experimental S. pneumoniae meningitis
Pedersen, M., Brandt, Christian Thomas, Knudsen, Gitte Moos, Østergaard, C., Skinhøj, P., Frimodt-Møller, N. & Møller, Kirsten, 2007, In: Journal of Applied Physiology. 102, 72-78Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of S. pneumoniae bacteremia on cerebral blood flow autoregulation in rats
Pedersen, M., Brandt, C. T., Knudsen, Gitte Moos, Østergaard, C., Skinhøj, P., Skovsted, I. C., Frimodt-Møller, N. & Møller, Kirsten, 2008, In: Journal of Cerebral Blood Flow and Metabolism. 28, 1, p. 126-134 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of strategic cortical infarctions on pupillary function
Peinkhofer, C., Martens, P., Grand, J., Truelsen, T., Knudsen, Gitte Moos, Kjaergaard, J. & Kondziella, Daniel, 2018, In: Frontiers in Neurology. 9, p. 1-8 8 p., 916.Research output: Contribution to journal › Journal article › Research › peer-review
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Cortical modulation of pupillary function: systematic review
Peinkhofer, C., Knudsen, Gitte Moos, Moretti, R. & Kondziella, Daniel, 2019, In: PeerJ. 7, 38 p., e6882.Research output: Contribution to journal › Review › Research › peer-review
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Application of advanced brain positron emission tomography–based molecular imaging for a biological framework in neurodegenerative proteinopathies
IMBI Brain Imaging Working Group, I. B. I. W. G., 1 Dec 2019, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11, p. 327-332 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A new perspective for advanced positron emission tomography–based molecular imaging in neurodegenerative proteinopathies
IMBI Project, I. P., 1 Jan 2019, In: Alzheimer's and Dementia. 15, 8, p. 1081-1103Research output: Contribution to journal › Journal article › Research › peer-review
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Testosterone levels in healthy men correlate negatively with serotonin 4 receptor binding
Perfalk, E., Cunha-Bang, S. D., Holst, K. K., Keller, S., Svarer, C., Knudsen, Gitte Moos & Frokjaer, V. G., Jul 2017, In: Psychoneuroendocrinology. 81, p. 22-28 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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18F-Labelling of electron rich iodonium ylides: application to the radiosynthesis of potential 5-HT2A receptor PET ligands
Petersen, I. N., Villadsen, J., Hansen, H. D., Madsen, J., Jensen, Anders A., Gillings, N., Lehel, S., Herth, Matthias Manfred, Knudsen, Gitte Moos & Kristensen, Jesper Langgaard, Apr 2017, In: Organic & Biomolecular Chemistry. 15, p. 4351-4358Research output: Contribution to journal › Journal article › Research › peer-review
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Assessment of the neuronal underpinnings of cognitive impairment in bipolar disorder with a picture encoding paradigm and methodological lessons learnt
Petersen, J. Z., Macoveanu, J., Kjærstad, H. L., Knudsen, Gitte Moos, Kessing, Lars Vedel & Miskowiak, Kamilla, 2021, In: Journal of Psychopharmacology. 35, 8, p. 983-991 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of recombinant human erythropoietin on cognition and neural activity in remitted patients with mood disorders and first-degree relatives of patients with psychiatric disorders: A study protocol for a randomized controlled trial
Petersen, J. Z., Schmidt, L. S., Vinberg, Maj, Jørgensen, Martin Balslev, Hageman, Ida, Ehrenreich, H., Knudsen, Gitte Moos, Kessing, Lars Vedel & Miskowiak, Kamilla, 6 Nov 2018, In: Trials. 19, 611.Research output: Contribution to journal › Journal article › Research › peer-review
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Dopamine D(2) receptor quantification in extrastriatal brain regions using [(123)I]epidepride with bolus/infusion
Pinborg, Lars Hageman, Videbaek, C., Knudsen, Gitte Moos, Swahn, C. G., Halldin, C., Friberg, L., Paulson, Olaf B. & Lassen, N. A., 15 Jun 2000, In: Synapse (New York, N.Y.). 36, 4, p. 322-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Benzodiazepine receptor quantification in Huntington's disease with [(123)I]omazenil and SPECT
Pinborg, Lars Hageman, Videbaek, C., Hasselbalch, Steen, Sørensen, S. A., Wagner, A., Paulson, Olaf B. & Knudsen, Gitte Moos, May 2001, In: Journal of neurology, neurosurgery, and psychiatry. 70, 5, p. 657-61 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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[123I]epidepride binding to cerebellar dopamine D2/D3 receptors is displaceable: implications for the use of cerebellum as a reference region
Pinborg, Lars Hageman, Videbaek, C., Ziebell, M., Mackeprang, T., Friberg, L., Rasmussen, H., Knudsen, Gitte Moos & Glenthøj, Birte Yding, 15 Feb 2007, In: NeuroImage. 34, 4, p. 1450-3 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The 5-HT2A receptor binding pattern in the human brain is strongly genetically determined
Pinborg, Lars Hageman, Arfan, H., Haugbol, S., Kyvik, K. O., Hjelmborg, J. V. B., Svarer, C., Frokjaer, V. G., Paulson, Olaf B., Holm, S. & Knudsen, Gitte Moos, 2007, In: NeuroImage. 40, 3, p. 1175-1180 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Quantification of [(123)I]PE2I binding to dopamine transporters with SPET
Pinborg, Lars Hageman, Videbaek, C., Svarer, C., Yndgaard, S., Paulson, Olaf B. & Knudsen, Gitte Moos, May 2002, In: European Journal of Nuclear Medicine and Molecular Imaging. 29, 5, p. 623-31 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Quantification of 123I-PE2I binding to dopamine transporter with SPECT after bolus and bolus/infusion
Pinborg, Lars Hageman, Ziebell, M., Frøkjær, Vibe Gedsø, de Nijs, R., Svarer, C., Haugbøl, S., Yndgaard, S. & Knudsen, Gitte Moos, 1 Jul 2005, In: Journal of Nuclear Medicine. 46, 7, p. 1119-27 9 p.Research output: Contribution to journal › Journal article › Research
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Serotonin 4 receptor binding is positively associated with brain response to reward
Poulsen, Anne, Dam, V. N. H., Landman, E. B., Köhler-Forsberg, K., Larsen, S. V., Ozenne, Brice Maxime Hugues, Fisher, P. M., Knudsen, Gitte Moos & Frøkjær, V. G., 2019, In: Journal of Cerebral Blood Flow and Metabolism. 39, Supplement 1, p. 538 1 p., PP01-O02.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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In vivo PET Imaging of [11C]CIMBI-5, a 5-HT2AR Agonist Radiotracer in Nonhuman Primates
Prabhakaran, J., DeLorenzo, C., Zanderigo, F., Knudsen, Gitte Moos, Gilling, N., Pratap, M., Jorgensen, M. J., Daunais, J., Kaplan, J. R., Parsey, R. V., Mann, J. J. & Kumar, D., 2019, In: Journal of Pharmacy and Pharmaceutical Sciences. 22, p. 352-364Research output: Contribution to journal › Journal article › Research › peer-review
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Development of the First Tritiated Tetrazine: Facilitating Tritiation of Proteins
Radjani Bidesi, N. S., Battisti, Umberto Maria, Lopes van de Broek, S., Shalgunov, Vladimir, Dall, A., Bøggild Kristensen, J., Sehlin, D., Syvänen, S., Knudsen, Gitte Moos & Herth, Matthias Manfred, 2022, In: ChemBioChem. 23, 23, 7 p., e202200539.Research output: Contribution to journal › Journal article › Research › peer-review
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Low frontal serotonin 2A receptor binding is a state marker for schizophrenia?
Rasmussen, H., Frokjaer, V. G., Hilker, R. W., Madsen, J., Anhøj, S., Oranje, B., Pinborg, Lars Hageman, Glenthøj, Birte Yding & Knudsen, Gitte Moos, Jul 2016, In: European Neuropsychopharmacology. 26, 7, p. 1248-50 3 p.Research output: Contribution to journal › Letter › Research › peer-review
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Decreased frontal serotonin2A receptor binding in antipsychotic-naive patients with first-episode schizophrenia
Rasmussen, H., Erritzoe, D., Andersen, R., Ebdrup, B. H., Aggernaes, B., Oranje, B., Kalbitzer, J., Madsen, J., Pinborg, Lars Hageman, Baaré, W., Svarer, C., Lublin, H., Knudsen, Gitte Moos & Glenthøj, Birte Yding, 1 Jan 2010, In: Archives of General Psychiatry. 67, 1, p. 9-16 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Serotonin2A receptor blockade and clinical effect in first-episode schizophrenia patients treated with quetiapine
Rasmussen, H., Ebdrup, B. H., Erritzoe, D., Aggernaes, B., Oranje, B., Kalbitzer, J. G. M., Pinborg, Lars Hageman, Baaré, W. F. C., Svarer, C., Lublin, H., Knudsen, Gitte Moos & Glenthøj, Birte Yding, 2011, In: Psychopharmacology. 213, p. 583-592 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impaired oxidative capacity due to decreased CPT1b levels as a contributing factor to fat accumulation in obesity
Ratner, C., Madsen, A. N., Kristensen, L. V., Skov, Louise Julie, Pedersen, K. S., Mortensen, Ole Hartvig, Knudsen, Gitte Moos, Raun, K. & Holst, Birgitte, 8 Apr 2015, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 308, 11, p. R973-R982 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A single dose of psilocybin increases synaptic density and decreases 5-HT2A receptor density in the pig brain
Raval, N. R., Johansen, A., Donovan, L. L., Ros, N. F., Ozenne, Brice Maxime Hugues, Hansen, H. D. & Knudsen, Gitte Moos, 2020, In: European Neuropsychopharmacology. 40, Supplement 1, p. S453-S454 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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A single dose of psilocybin increases synaptic density and decreases 5-HT2A receptor density in the pig brain
Raval, N. R., Johansen, A., Donovan, L. L., Ros, N. F., Ozenne, Brice Maxime Hugues, Hansen, H. D. & Knudsen, Gitte Moos, 2021, In: International Journal of Molecular Sciences. 22, 2, 14 p., 835.Research output: Contribution to journal › Journal article › Research › peer-review
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Synaptic Density and Neuronal Metabolic Function Measured by Positron Emission Tomography in the Unilateral 6-OHDA Rat Model of Parkinson’s Disease
Raval, N. R., Gudmundsen, F., Juhl, M., Andersen, Ida Vang, Speth, N., Videbæk, A., Petersen, I. N., Mikkelsen, Jens D., Fisher, P. M. D., Herth, Matthias Manfred, Plavén-Sigray, P., Knudsen, Gitte Moos & Palner, M., 2021, In: Frontiers in Synaptic Neuroscience. 13, 13 p., 715811.Research output: Contribution to journal › Journal article › Research › peer-review
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An in vivo Pig Model for Testing Novel Positron Emission Tomography Radioligands Targeting Cerebral Protein Aggregates
Raval, N. R., Nasser, A., Madsen, C. A., Beschorner, Natalie, Beaman, Emily Eufaula, Juhl, M., Lehel, S., Palner, M., Svarer, C., Plavén-Sigray, P., Jørgensen, Louise Møller & Knudsen, Gitte Moos, 2022, In: Frontiers in Neuroscience. 16, 12 p., 847074.Research output: Contribution to journal › Journal article › Research › peer-review
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Evaluation of the α-synuclein PET radiotracer (d3)-[11C]MODAG-001 in pigs
Raval, N. R., Madsen, C. A., Shalgunov, Vladimir, Nasser, A., Battisti, Umberto Maria, Beaman, Emily Eufaula, Juhl, M., Jørgensen, Louise Møller, Herth, Matthias Manfred, Hansen, H. D., Plavén-Sigray, P. & Knudsen, Gitte Moos, 2022, In: Nuclear Medicine and Biology. 114-115, p. 42-48Research output: Contribution to journal › Journal article › Research › peer-review
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Radiolabelling and PET brain imaging of the a1-adrenoceptor antagonist Lu AE43936
Risgaard, R., Ettrup, A. J., Balle, T., Dyssegaard, A., Hansen, H. D., Lehel, S., Madsen, J., Pedersen, H., Püschl, A., Badolo, L., Bang-Andersen, B., Knudsen, Gitte Moos & Kristensen, Jesper Langgaard, 2013, In: Nuclear Medicine & Biology. 40, 1, p. 135-140 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association between brain serotonin 4 receptor binding and reactivity to emotional faces in depressed and healthy individuals
Sankar, A., Ozenne, Brice Maxime Hugues, Dam, Vibeke Høyrup, Svarer, C., Jørgensen, Martin Balslev, Miskowiak, Kamilla, Frøkjær, Vibe Gedsø, Knudsen, Gitte Moos & Fisher, Patrick Mac Donald, 2023, In: Translational Psychiatry. 13, 1, 7 p., 165.Research output: Contribution to journal › Journal article › Research › peer-review
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Association of neurocognitive function with psychiatric hospitalization and socio-demographic conditions in individuals with bipolar and major depressive disorders
Sankar, A., Ziersen, Simon Christoffer, Ozenne, Brice Maxime Hugues, Beaman, Emily Eufaula, Dam, Vibeke Høyrup, Fisher, Patrick Mac Donald, Knudsen, Gitte Moos, Kessing, Lars Vedel, Frøkjær, Vibe Gedsø & Miskowiak, Kamilla, 2023, In: EClinicalMedicine. 58, 101927.Research output: Contribution to journal › Journal article › Research › peer-review
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Novelty-induced activity-regulated cytoskeletal-associated protein (Arc) expression in frontal cortex requires serotonin 2A receptor activation
Santini, M., Klein, A. B., El-Sayed, M., Ratner, C., Knudsen, Gitte Moos, Mikkelsen, J. D. & Aznar, S., 2011, In: Neuroscience. 190, p. 251-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Enhanced prefrontal serotonin 2A receptor signaling in the subchronic phencyclidine mouse model of schizophrenia
Santini, M. A., Ratner, C. F., Aznar, S., Klein, A. B., Knudsen, Gitte Moos, Mikkelsen, Jens D. & Klein, A. B., May 2013, In: Journal of Neuroscience Research. 91, 5, p. 634-41 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association of the leucine-7 to proline-7 variation in the signal sequence of neuropeptide Y with major depression
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The Bipolar Illness Onset study: research protocol for the BIO cohort study
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Design of Infusion Schemes for Neuroreceptor Imaging: Application to [(11)C]Flumazenil-PET Steady-State Study
Research output: Contribution to journal › Journal article › Research › peer-review
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