Amygdala signals subjective appetitiveness and aversiveness of mixed gambles
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Amygdala signals subjective appetitiveness and aversiveness of mixed gambles. / Gelskov, Sofie V; Henningsson, Susanne; Madsen, Kristoffer H; Siebner, Hartwig R; Ramsøy, Thomas Z.
In: Cortex, Vol. 66, 2015, p. 81-90.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Amygdala signals subjective appetitiveness and aversiveness of mixed gambles
AU - Gelskov, Sofie V
AU - Henningsson, Susanne
AU - Madsen, Kristoffer H
AU - Siebner, Hartwig R
AU - Ramsøy, Thomas Z
N1 - Copyright © 2015 Elsevier Ltd. All rights reserved.
PY - 2015
Y1 - 2015
N2 - People are more sensitive to losses than to equivalent gains when making financial decisions. We used functional magnetic resonance imaging (fMRI) to illuminate how the amygdala contributes to loss aversion. The blood oxygen level dependent (BOLD) response of the amygdala was mapped while healthy individuals were responding to 50/50 gambles with varying potential gain and loss amounts. Overall, subjects demanded twice as high potential gain as loss to accept a gamble. The individual level of loss aversion was expressed by the decision boundary, i.e., the gain-loss ratio at which subjects accepted and rejected gambles with equal probability. Amygdala activity increased the more the gain-loss ratio deviated from the individual decision boundary showing that the amygdala codes action value. This response pattern was more strongly expressed in loss aversive individuals, linking amygdala activity with individual differences in loss aversion. Together, the results show that the amygdala signals subjective appetitiveness or aversiveness of gain-loss ratios at the time of choice.
AB - People are more sensitive to losses than to equivalent gains when making financial decisions. We used functional magnetic resonance imaging (fMRI) to illuminate how the amygdala contributes to loss aversion. The blood oxygen level dependent (BOLD) response of the amygdala was mapped while healthy individuals were responding to 50/50 gambles with varying potential gain and loss amounts. Overall, subjects demanded twice as high potential gain as loss to accept a gamble. The individual level of loss aversion was expressed by the decision boundary, i.e., the gain-loss ratio at which subjects accepted and rejected gambles with equal probability. Amygdala activity increased the more the gain-loss ratio deviated from the individual decision boundary showing that the amygdala codes action value. This response pattern was more strongly expressed in loss aversive individuals, linking amygdala activity with individual differences in loss aversion. Together, the results show that the amygdala signals subjective appetitiveness or aversiveness of gain-loss ratios at the time of choice.
KW - Adult
KW - Amygdala
KW - Brain
KW - Brain Mapping
KW - Decision Making
KW - Functional Neuroimaging
KW - Gambling
KW - Humans
KW - Magnetic Resonance Imaging
KW - Male
KW - Risk-Taking
KW - Ventral Striatum
KW - Young Adult
U2 - 10.1016/j.cortex.2015.02.016
DO - 10.1016/j.cortex.2015.02.016
M3 - Journal article
C2 - 25817710
VL - 66
SP - 81
EP - 90
JO - Cortex
JF - Cortex
SN - 0010-9452
ER -
ID: 162370846