Calpain 3 is important for muscle regeneration: evidence from patients with limb girdle muscular dystrophies
Research output: Contribution to journal › Journal article › Research › peer-review
Limb girdle muscular dystrophy (LGMD) type 2A is caused by mutations in the CAPN3 gene and complete lack of functional calpain 3 leads to the most severe muscle wasting. Calpain 3 is suggested to be involved in maturation of contractile elements after muscle degeneration. The aim of this study was to investigate how mutations in the four functional domains of calpain 3 affect muscle regeneration.
| Original language | English |
|---|---|
| Journal | B M C Musculoskeletal Disorders |
| Volume | 13 |
| Pages (from-to) | 43-53 |
| Number of pages | 11 |
| ISSN | 1471-2474 |
| DOIs | |
| Publication status | Published - 2012 |
ID: 48603950