Determination of the luminal diameter of the radial artery in man by high frequency ultrasound: a methodological study
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Determination of the luminal diameter of the radial artery in man by high frequency ultrasound : a methodological study. / Nielsen, T H; Iversen, Helle Klingenberg; Tfelt-Hansen, P.
In: Ultrasound in Medicine & Biology, Vol. 16, No. 8, 1990, p. 787-91.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Determination of the luminal diameter of the radial artery in man by high frequency ultrasound
T2 - a methodological study
AU - Nielsen, T H
AU - Iversen, Helle Klingenberg
AU - Tfelt-Hansen, P
PY - 1990
Y1 - 1990
N2 - The validity and reproducibility of measurements of the luminal diameter of the radial artery in man were investigated with Dermascan A, a 20 MHz ultrasound scanner. The luminal diameter of a reference object, a plastic tube, was measured with ultrasound to be 99.0% of stereomicroscopic measurements. By comparing the diameter of the reference object either filled with water or blood at 37 degrees C, the ultrasound velocity in human blood at 37 degrees C was calculated to be 1605 m/s. The intraobserver repeatability coefficients of in-vivo measurements of the radial artery in man were in the same range, whether measurements were repeated after 30 min (14%) or from day to day (12%). The interobserver repeatability coefficient was acceptable (15%) when the site of measurements was marked, whereas measurements without a mark resulted in a repeatability coefficient of 24%. The intravenous administration of 0.5 mg ergotamine tartrate to 5 subjects caused a decrease in the mean luminal diameter of the radial artery from 2.94 mm to 2.42 mm 1 h after ergotamine (p less than 0.05). This ultrasound method for measurements of the luminal diameter should thus be suitable for investigating the effects of physiological and pharmacological stimuli on the arteries per se.
AB - The validity and reproducibility of measurements of the luminal diameter of the radial artery in man were investigated with Dermascan A, a 20 MHz ultrasound scanner. The luminal diameter of a reference object, a plastic tube, was measured with ultrasound to be 99.0% of stereomicroscopic measurements. By comparing the diameter of the reference object either filled with water or blood at 37 degrees C, the ultrasound velocity in human blood at 37 degrees C was calculated to be 1605 m/s. The intraobserver repeatability coefficients of in-vivo measurements of the radial artery in man were in the same range, whether measurements were repeated after 30 min (14%) or from day to day (12%). The interobserver repeatability coefficient was acceptable (15%) when the site of measurements was marked, whereas measurements without a mark resulted in a repeatability coefficient of 24%. The intravenous administration of 0.5 mg ergotamine tartrate to 5 subjects caused a decrease in the mean luminal diameter of the radial artery from 2.94 mm to 2.42 mm 1 h after ergotamine (p less than 0.05). This ultrasound method for measurements of the luminal diameter should thus be suitable for investigating the effects of physiological and pharmacological stimuli on the arteries per se.
KW - Adult
KW - Arteries
KW - Ergotamine
KW - Female
KW - Forearm
KW - Humans
KW - Injections, Intravenous
KW - Male
KW - Models, Cardiovascular
KW - Observer Variation
KW - Reproducibility of Results
KW - Ultrasonography
M3 - Journal article
C2 - 2095008
VL - 16
SP - 787
EP - 791
JO - Ultrasound in Medicine & Biology
JF - Ultrasound in Medicine & Biology
SN - 0301-5629
IS - 8
ER -
ID: 128984793