fMRI in Parkinson’s Disease

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

Standard

fMRI in Parkinson’s Disease. / Siebner, Hartwig R.; Meder, David; Herz, Damian M.

fMRI: Basics and Clinical Applications. ed. / Stephan Ulmer; Olav Jansen. Springer Publishing Company, 2020. p. 417-431.

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

Harvard

Siebner, HR, Meder, D & Herz, DM 2020, fMRI in Parkinson’s Disease. in S Ulmer & O Jansen (eds), fMRI: Basics and Clinical Applications. Springer Publishing Company, pp. 417-431. https://doi.org/10.1007/978-3-030-41874-8_26

APA

Siebner, H. R., Meder, D., & Herz, D. M. (2020). fMRI in Parkinson’s Disease. In S. Ulmer, & O. Jansen (Eds.), fMRI: Basics and Clinical Applications (pp. 417-431). Springer Publishing Company. https://doi.org/10.1007/978-3-030-41874-8_26

Vancouver

Siebner HR, Meder D, Herz DM. fMRI in Parkinson’s Disease. In Ulmer S, Jansen O, editors, fMRI: Basics and Clinical Applications. Springer Publishing Company. 2020. p. 417-431 https://doi.org/10.1007/978-3-030-41874-8_26

Author

Siebner, Hartwig R. ; Meder, David ; Herz, Damian M. / fMRI in Parkinson’s Disease. fMRI: Basics and Clinical Applications. editor / Stephan Ulmer ; Olav Jansen. Springer Publishing Company, 2020. pp. 417-431

Bibtex

@inbook{6d653386561b4019b847296f1ae75966,
title = "fMRI in Parkinson{\textquoteright}s Disease",
abstract = "In this chapter, we review recent advances in functional magnetic resonance imaging (fMRI) in Parkinson{\textquoteright}s disease (PD). Covariance patterns of regional resting-state activity in functional brain networks can be used to distinguish Parkinson patients from healthy controls and might play an important role as a biomarker in the future. Thee analyses of motor activity and connectivity have revealed compensatory mechanisms for impaired function of cortico-subcortical feedback loops and have shown how attentional mechanisms modulate the activity in motor loops. Other fMRI studies probing cognitive functions and reward-related behavior have shown that dopamine replacement can have detrimental effects on non-motor brain functions by altering physiological patterns of dopaminergic signaling. Neuroimaging can also be used to assess preclinical compensation of striatal dopaminergic denervation by studying asymptomatic carriers of mutations in genes that can cause PD. In conclusion, fMRI is a powerful tool to monitor changes in functional neural networks and has given important new insights into the pathophysiology of PD.",
author = "Siebner, {Hartwig R.} and David Meder and Herz, {Damian M.}",
year = "2020",
doi = "10.1007/978-3-030-41874-8_26",
language = "English",
isbn = "978-3-030-41873-1",
pages = "417--431",
editor = "Stephan Ulmer and Olav Jansen",
booktitle = "fMRI",
publisher = "Springer Publishing Company",

}

RIS

TY - CHAP

T1 - fMRI in Parkinson’s Disease

AU - Siebner, Hartwig R.

AU - Meder, David

AU - Herz, Damian M.

PY - 2020

Y1 - 2020

N2 - In this chapter, we review recent advances in functional magnetic resonance imaging (fMRI) in Parkinson’s disease (PD). Covariance patterns of regional resting-state activity in functional brain networks can be used to distinguish Parkinson patients from healthy controls and might play an important role as a biomarker in the future. Thee analyses of motor activity and connectivity have revealed compensatory mechanisms for impaired function of cortico-subcortical feedback loops and have shown how attentional mechanisms modulate the activity in motor loops. Other fMRI studies probing cognitive functions and reward-related behavior have shown that dopamine replacement can have detrimental effects on non-motor brain functions by altering physiological patterns of dopaminergic signaling. Neuroimaging can also be used to assess preclinical compensation of striatal dopaminergic denervation by studying asymptomatic carriers of mutations in genes that can cause PD. In conclusion, fMRI is a powerful tool to monitor changes in functional neural networks and has given important new insights into the pathophysiology of PD.

AB - In this chapter, we review recent advances in functional magnetic resonance imaging (fMRI) in Parkinson’s disease (PD). Covariance patterns of regional resting-state activity in functional brain networks can be used to distinguish Parkinson patients from healthy controls and might play an important role as a biomarker in the future. Thee analyses of motor activity and connectivity have revealed compensatory mechanisms for impaired function of cortico-subcortical feedback loops and have shown how attentional mechanisms modulate the activity in motor loops. Other fMRI studies probing cognitive functions and reward-related behavior have shown that dopamine replacement can have detrimental effects on non-motor brain functions by altering physiological patterns of dopaminergic signaling. Neuroimaging can also be used to assess preclinical compensation of striatal dopaminergic denervation by studying asymptomatic carriers of mutations in genes that can cause PD. In conclusion, fMRI is a powerful tool to monitor changes in functional neural networks and has given important new insights into the pathophysiology of PD.

U2 - 10.1007/978-3-030-41874-8_26

DO - 10.1007/978-3-030-41874-8_26

M3 - Book chapter

SN - 978-3-030-41873-1

SP - 417

EP - 431

BT - fMRI

A2 - Ulmer, Stephan

A2 - Jansen, Olav

PB - Springer Publishing Company

ER -

ID: 260249648