In vivo imaging of cerebral serotonin transporter and serotonin(2A) receptor binding in 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") and hallucinogen users

Research output: Contribution to journalJournal articleResearchpeer-review

  • David Erritzoe
  • Vibe Frøkjær
  • Klaus K Holst
  • Maria Christoffersen
  • Sys Stybe Johansen
  • Claus Svarer
  • Jacob Madsen
  • Peter M Rasmussen
  • Thomas Ramsøy
  • Terry L Jernigan
  • Knudsen, Gitte Moos
Both hallucinogens and 3,4-methylenedioxymethamphetamine (MDMA or "ecstasy") have direct agonistic effects on postsynaptic serotonin(2A) receptors, the key site for hallucinogenic actions. In addition, MDMA is a potent releaser and reuptake inhibitor of presynaptic serotonin.
Original languageEnglish
JournalArchives of General Psychiatry
Volume68
Issue number6
Pages (from-to)562-76
Number of pages15
ISSN0003-990X
DOIs
Publication statusPublished - 2011

ID: 40165142