Low frontal serotonin 2A receptor binding is a state marker for schizophrenia?

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Standard

Low frontal serotonin 2A receptor binding is a state marker for schizophrenia? / Rasmussen, Hans; Frokjaer, Vibe G; Hilker, Rikke W; Madsen, Jacob; Anhøj, Simon; Oranje, Bob; Pinborg, Lars H; Glenthøj, Birte; Knudsen, Gitte M.

In: European Neuropsychopharmacology, Vol. 26, No. 7, 07.2016, p. 1248-50.

Research output: Contribution to journal › Letter › Research › peer-review

Harvard

Rasmussen, H, Frokjaer, VG, Hilker, RW, Madsen, J, Anhøj, S, Oranje, B, Pinborg, LH, Glenthøj, B & Knudsen, GM 2016, 'Low frontal serotonin 2A receptor binding is a state marker for schizophrenia?', European Neuropsychopharmacology, vol. 26, no. 7, pp. 1248-50. https://doi.org/10.1016/j.euroneuro.2016.04.008

APA

Rasmussen, H., Frokjaer, V. G., Hilker, R. W., Madsen, J., Anhøj, S., Oranje, B., Pinborg, L. H., Glenthøj, B., & Knudsen, G. M. (2016). Low frontal serotonin 2A receptor binding is a state marker for schizophrenia? European Neuropsychopharmacology, 26(7), 1248-50. https://doi.org/10.1016/j.euroneuro.2016.04.008

Vancouver

Rasmussen H, Frokjaer VG, Hilker RW, Madsen J, Anhøj S, Oranje B et al. Low frontal serotonin 2A receptor binding is a state marker for schizophrenia? European Neuropsychopharmacology. 2016 Jul;26(7):1248-50. https://doi.org/10.1016/j.euroneuro.2016.04.008

Author

Rasmussen, Hans ; Frokjaer, Vibe G ; Hilker, Rikke W ; Madsen, Jacob ; Anhøj, Simon ; Oranje, Bob ; Pinborg, Lars H ; Glenthøj, Birte ; Knudsen, Gitte M. / Low frontal serotonin 2A receptor binding is a state marker for schizophrenia?. In: European Neuropsychopharmacology. 2016 ; Vol. 26, No. 7. pp. 1248-50.

Bibtex

@article{579a57cd04d04dcfb162450c745b59a1,

title = "Low frontal serotonin 2A receptor binding is a state marker for schizophrenia?",

abstract = "Here we imaged serotonin 2A receptor (5-HT2AR) binding in a very rare population of monozygotic twins discordant for schizophrenia to provide insight into trait and state components in brain 5-HT2AR patterns. In four twin pairs not medicated with drugs that target 5-HT2AR, frontal 5-HT2AR binding was consistently lower (33%) in schizophrenic- relative to their healthy co-twins. Our results strongly imply low frontal 5-HT2AR availability as a state feature of schizophrenia. If replicated, ideally in a larger sample also including dizygotic twin pairs and drug-na{\"i}ve patients, this finding critically advance our understanding of the complex pathophysiology of schizophrenia.",

keywords = "Journal Article",

author = "Hans Rasmussen and Frokjaer, {Vibe G} and Hilker, {Rikke W} and Jacob Madsen and Simon Anh{\o}j and Bob Oranje and Pinborg, {Lars H} and Birte Glenth{\o}j and Knudsen, {Gitte M}",

year = "2016",

month = jul,

doi = "10.1016/j.euroneuro.2016.04.008",

language = "English",

volume = "26",

pages = "1248--50",

journal = "European Neuropsychopharmacology",

issn = "0924-977X",

publisher = "Elsevier",

number = "7",