Mapping brain activity on the verge of a photically induced generalized tonic-clonic seizure

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Standard

Mapping brain activity on the verge of a photically induced generalized tonic-clonic seizure. / Moeller, Friederike; Siebner, Hartwig R; Wolff, Stephan; Muhle, Hiltrud; Granert, Oliver; Jansen, Olav; Stephani, Ulrich; Siniatchkin, Michael.

In: Epilepsia, Vol. 50, No. 6, 2009, p. 1632-7.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Moeller, F, Siebner, HR, Wolff, S, Muhle, H, Granert, O, Jansen, O, Stephani, U & Siniatchkin, M 2009, 'Mapping brain activity on the verge of a photically induced generalized tonic-clonic seizure', Epilepsia, vol. 50, no. 6, pp. 1632-7. https://doi.org/10.1111/j.1528-1167.2009.02011.x

APA

Moeller, F., Siebner, H. R., Wolff, S., Muhle, H., Granert, O., Jansen, O., Stephani, U., & Siniatchkin, M. (2009). Mapping brain activity on the verge of a photically induced generalized tonic-clonic seizure. Epilepsia, 50(6), 1632-7. https://doi.org/10.1111/j.1528-1167.2009.02011.x

Vancouver

Moeller F, Siebner HR, Wolff S, Muhle H, Granert O, Jansen O et al. Mapping brain activity on the verge of a photically induced generalized tonic-clonic seizure. Epilepsia. 2009;50(6):1632-7. https://doi.org/10.1111/j.1528-1167.2009.02011.x

Author

Moeller, Friederike ; Siebner, Hartwig R ; Wolff, Stephan ; Muhle, Hiltrud ; Granert, Oliver ; Jansen, Olav ; Stephani, Ulrich ; Siniatchkin, Michael. / Mapping brain activity on the verge of a photically induced generalized tonic-clonic seizure. In: Epilepsia. 2009 ; Vol. 50, No. 6. pp. 1632-7.

Bibtex

@article{c377f440aac211df928f000ea68e967b,
title = "Mapping brain activity on the verge of a photically induced generalized tonic-clonic seizure",
abstract = "In a photosensitive patient intermittent photic stimulation (IPS) accidentally provoked a generalized tonic-clonic seizure during simultaneous recordings of electroencephalography (EEG) and functional magnetic resonance imaging (fMRI). Before seizure onset, IPS consistently induced generalized photoparoxysmal responses (PPRs). These PPRs were associated with increases in blood oxygen level dependent (BOLD) signal in the visual cortex, the thalamus, and both superior colliculi, and a decrease in BOLD signal in the frontoparietal areas. The BOLD signal in the visual cortex increased in magnitude during consecutive epochs of IPS associated with PPRs. We propose that repeated IPS led to an excessive amount of neuronal activity in the visual cortex that evoked PPRs and finally exceeded a critical threshold and triggered a generalized seizure.",
author = "Friederike Moeller and Siebner, {Hartwig R} and Stephan Wolff and Hiltrud Muhle and Oliver Granert and Olav Jansen and Ulrich Stephani and Michael Siniatchkin",
note = "Keywords: Adolescent; Brain; Brain Mapping; Electroencephalography; Female; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Oxygen; Photic Stimulation; Retrospective Studies; Seizures",
year = "2009",
doi = "10.1111/j.1528-1167.2009.02011.x",
language = "English",
volume = "50",
pages = "1632--7",
journal = "Epilepsia",
issn = "0013-9580",
publisher = "Wiley-Blackwell",
number = "6",

}

RIS

TY - JOUR

T1 - Mapping brain activity on the verge of a photically induced generalized tonic-clonic seizure

AU - Moeller, Friederike

AU - Siebner, Hartwig R

AU - Wolff, Stephan

AU - Muhle, Hiltrud

AU - Granert, Oliver

AU - Jansen, Olav

AU - Stephani, Ulrich

AU - Siniatchkin, Michael

N1 - Keywords: Adolescent; Brain; Brain Mapping; Electroencephalography; Female; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Oxygen; Photic Stimulation; Retrospective Studies; Seizures

PY - 2009

Y1 - 2009

N2 - In a photosensitive patient intermittent photic stimulation (IPS) accidentally provoked a generalized tonic-clonic seizure during simultaneous recordings of electroencephalography (EEG) and functional magnetic resonance imaging (fMRI). Before seizure onset, IPS consistently induced generalized photoparoxysmal responses (PPRs). These PPRs were associated with increases in blood oxygen level dependent (BOLD) signal in the visual cortex, the thalamus, and both superior colliculi, and a decrease in BOLD signal in the frontoparietal areas. The BOLD signal in the visual cortex increased in magnitude during consecutive epochs of IPS associated with PPRs. We propose that repeated IPS led to an excessive amount of neuronal activity in the visual cortex that evoked PPRs and finally exceeded a critical threshold and triggered a generalized seizure.

AB - In a photosensitive patient intermittent photic stimulation (IPS) accidentally provoked a generalized tonic-clonic seizure during simultaneous recordings of electroencephalography (EEG) and functional magnetic resonance imaging (fMRI). Before seizure onset, IPS consistently induced generalized photoparoxysmal responses (PPRs). These PPRs were associated with increases in blood oxygen level dependent (BOLD) signal in the visual cortex, the thalamus, and both superior colliculi, and a decrease in BOLD signal in the frontoparietal areas. The BOLD signal in the visual cortex increased in magnitude during consecutive epochs of IPS associated with PPRs. We propose that repeated IPS led to an excessive amount of neuronal activity in the visual cortex that evoked PPRs and finally exceeded a critical threshold and triggered a generalized seizure.

U2 - 10.1111/j.1528-1167.2009.02011.x

DO - 10.1111/j.1528-1167.2009.02011.x

M3 - Journal article

C2 - 19400879

VL - 50

SP - 1632

EP - 1637

JO - Epilepsia

JF - Epilepsia

SN - 0013-9580

IS - 6

ER -

ID: 21456884