Mass dose effects and in vivo affinity in brain PET receptor studies--a study of cerebral 5-HT4 receptor binding with [11C]SB207145
Research output: Contribution to journal › Journal article › Research › peer-review
Attention to tracer dose principles is crucial in positron emission tomography (PET), and deviations can induce serious errors. In this study, we devise a method for determining receptor occupancy of the mass dose of the radioligand itself and the in vivo affinity.
Original language | English |
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Journal | Nuclear Medicine and Biology |
Volume | 38 |
Issue number | 8 |
Pages (from-to) | 1085-91 |
Number of pages | 7 |
ISSN | 0969-8051 |
DOIs | |
Publication status | Published - 2011 |
ID: 40215934