Mass dose effects and in vivo affinity in brain PET receptor studies--a study of cerebral 5-HT4 receptor binding with [11C]SB207145

Research output: Contribution to journalJournal articleResearchpeer-review

Attention to tracer dose principles is crucial in positron emission tomography (PET), and deviations can induce serious errors. In this study, we devise a method for determining receptor occupancy of the mass dose of the radioligand itself and the in vivo affinity.
Original languageEnglish
JournalNuclear Medicine and Biology
Volume38
Issue number8
Pages (from-to)1085-91
Number of pages7
ISSN0969-8051
DOIs
Publication statusPublished - 2011

ID: 40215934