MRI-guided region-of-interest delineation is comparable to manual delineation in dopamine transporter SPECT quantification in patients: a reproducibility study
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
MRI-guided region-of-interest delineation is comparable to manual delineation in dopamine transporter SPECT quantification in patients: a reproducibility study. / Ziebell, Morten; Pinborg, Lars H; Thomsen, Gerda; de Nijs, Robin; Svarer, Claus; Wagner, Aase; Knudsen, Gitte M.
In: Journal of Nuclear Medicine Technology, Vol. 38, No. 2, 01.06.2010, p. 61-8.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - MRI-guided region-of-interest delineation is comparable to manual delineation in dopamine transporter SPECT quantification in patients: a reproducibility study
AU - Ziebell, Morten
AU - Pinborg, Lars H
AU - Thomsen, Gerda
AU - de Nijs, Robin
AU - Svarer, Claus
AU - Wagner, Aase
AU - Knudsen, Gitte M
PY - 2010/6/1
Y1 - 2010/6/1
N2 - A particularly sensitive step in the quantification of SPECT images of the dopamine transporter (DAT) is a correct delineation of the region of interest (ROI). In this study, we primarily compared the reproducibility of the following different approaches for ROI delineation in SPECT images of the DAT: the use of manual delineation (MD) on high-count striatal slides directly on the SPECT image, ROI delineation based on individual MR images (MRD), and oversized striatal ROIs-that is, the striatal volume of interest (SVI), as described previously. We also assessed the ability of the different approaches to identify striatal pathology in patients with parkinsonism.
AB - A particularly sensitive step in the quantification of SPECT images of the dopamine transporter (DAT) is a correct delineation of the region of interest (ROI). In this study, we primarily compared the reproducibility of the following different approaches for ROI delineation in SPECT images of the DAT: the use of manual delineation (MD) on high-count striatal slides directly on the SPECT image, ROI delineation based on individual MR images (MRD), and oversized striatal ROIs-that is, the striatal volume of interest (SVI), as described previously. We also assessed the ability of the different approaches to identify striatal pathology in patients with parkinsonism.
U2 - http://dx.doi.org/10.2967/jnmt.109.072801
DO - http://dx.doi.org/10.2967/jnmt.109.072801
M3 - Journal article
VL - 38
SP - 61
EP - 68
JO - Journal of Nuclear Medicine Technology
JF - Journal of Nuclear Medicine Technology
SN - 0091-4916
IS - 2
ER -
ID: 34094241