No effect of pure oxygen inhalation on headache induced by glyceryl trinitrate

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

No effect of pure oxygen inhalation on headache induced by glyceryl trinitrate. / Daugaard, D.; Tfelt-Hansen, P.; Thomsen, L.L.; Iversen, H.K.; Olesen, Jes.

In: Journal of Headache and Pain, Vol. 11, No. 2, 2010, p. 93-95.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Daugaard, D, Tfelt-Hansen, P, Thomsen, LL, Iversen, HK & Olesen, J 2010, 'No effect of pure oxygen inhalation on headache induced by glyceryl trinitrate', Journal of Headache and Pain, vol. 11, no. 2, pp. 93-95.

APA

Daugaard, D., Tfelt-Hansen, P., Thomsen, L. L., Iversen, H. K., & Olesen, J. (2010). No effect of pure oxygen inhalation on headache induced by glyceryl trinitrate. Journal of Headache and Pain, 11(2), 93-95.

Vancouver

Daugaard D, Tfelt-Hansen P, Thomsen LL, Iversen HK, Olesen J. No effect of pure oxygen inhalation on headache induced by glyceryl trinitrate. Journal of Headache and Pain. 2010;11(2):93-95.

Author

Daugaard, D. ; Tfelt-Hansen, P. ; Thomsen, L.L. ; Iversen, H.K. ; Olesen, Jes. / No effect of pure oxygen inhalation on headache induced by glyceryl trinitrate. In: Journal of Headache and Pain. 2010 ; Vol. 11, No. 2. pp. 93-95.

Bibtex

@article{ffc7c2e668934ef39ee8660786bc2b7a,
title = "No effect of pure oxygen inhalation on headache induced by glyceryl trinitrate",
abstract = "Inhalation of hyperbaric oxygen has been used as an experimental treatment for migraine and pure oxygen is an established treatment for cluster headache. Intravenous glyceryl trinitrate (GTN) is an established headache model. In the present study the possibility of decreasing the headache by inhalation of pure oxygen was explored in a double-blind crossover design in 18 healthy subjects. Inhalation of air served as placebo. The subjects received intravenous GTN (0.25 A mu g/kg/min) for 20 min. Headache was scored for 85 min. Sixteen of 18 (89%) subjects experienced GTN-induced headache after O-2-inhalation and 17/18 (94%) experienced GTN-induced headache after air. The mean peak headache scores were 1.9 and 2.4, respectively, on a numerical scale of 0-10. Oxygen inhalation did not have effect on GTN-induced headache, most likely because the theoretical decrease in NO levels, due to faster metabolism of NO, is too small to be detected in the GTN headache model",
author = "D. Daugaard and P. Tfelt-Hansen and L.L. Thomsen and H.K. Iversen and Jes Olesen",
year = "2010",
language = "English",
volume = "11",
pages = "93--95",
journal = "Journal of Headache and Pain",
issn = "1129-2369",
publisher = "Springer",
number = "2",

}

RIS

TY - JOUR

T1 - No effect of pure oxygen inhalation on headache induced by glyceryl trinitrate

AU - Daugaard, D.

AU - Tfelt-Hansen, P.

AU - Thomsen, L.L.

AU - Iversen, H.K.

AU - Olesen, Jes

PY - 2010

Y1 - 2010

N2 - Inhalation of hyperbaric oxygen has been used as an experimental treatment for migraine and pure oxygen is an established treatment for cluster headache. Intravenous glyceryl trinitrate (GTN) is an established headache model. In the present study the possibility of decreasing the headache by inhalation of pure oxygen was explored in a double-blind crossover design in 18 healthy subjects. Inhalation of air served as placebo. The subjects received intravenous GTN (0.25 A mu g/kg/min) for 20 min. Headache was scored for 85 min. Sixteen of 18 (89%) subjects experienced GTN-induced headache after O-2-inhalation and 17/18 (94%) experienced GTN-induced headache after air. The mean peak headache scores were 1.9 and 2.4, respectively, on a numerical scale of 0-10. Oxygen inhalation did not have effect on GTN-induced headache, most likely because the theoretical decrease in NO levels, due to faster metabolism of NO, is too small to be detected in the GTN headache model

AB - Inhalation of hyperbaric oxygen has been used as an experimental treatment for migraine and pure oxygen is an established treatment for cluster headache. Intravenous glyceryl trinitrate (GTN) is an established headache model. In the present study the possibility of decreasing the headache by inhalation of pure oxygen was explored in a double-blind crossover design in 18 healthy subjects. Inhalation of air served as placebo. The subjects received intravenous GTN (0.25 A mu g/kg/min) for 20 min. Headache was scored for 85 min. Sixteen of 18 (89%) subjects experienced GTN-induced headache after O-2-inhalation and 17/18 (94%) experienced GTN-induced headache after air. The mean peak headache scores were 1.9 and 2.4, respectively, on a numerical scale of 0-10. Oxygen inhalation did not have effect on GTN-induced headache, most likely because the theoretical decrease in NO levels, due to faster metabolism of NO, is too small to be detected in the GTN headache model

M3 - Journal article

VL - 11

SP - 93

EP - 95

JO - Journal of Headache and Pain

JF - Journal of Headache and Pain

SN - 1129-2369

IS - 2

ER -

ID: 34163798