Polysomnographic indicators of mortality in stroke patients

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Polysomnographic indicators of mortality in stroke patients. / Ponsaing, Laura B; Iversen, Helle K; Jennum, Poul.

In: Sleep and Breathing, Vol. 21, No. 2, 05.2017, p. 235-242.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Ponsaing, LB, Iversen, HK & Jennum, P 2017, 'Polysomnographic indicators of mortality in stroke patients', Sleep and Breathing, vol. 21, no. 2, pp. 235-242. https://doi.org/10.1007/s11325-016-1387-z

APA

Ponsaing, L. B., Iversen, H. K., & Jennum, P. (2017). Polysomnographic indicators of mortality in stroke patients. Sleep and Breathing, 21(2), 235-242. https://doi.org/10.1007/s11325-016-1387-z

Vancouver

Ponsaing LB, Iversen HK, Jennum P. Polysomnographic indicators of mortality in stroke patients. Sleep and Breathing. 2017 May;21(2):235-242. https://doi.org/10.1007/s11325-016-1387-z

Author

Ponsaing, Laura B ; Iversen, Helle K ; Jennum, Poul. / Polysomnographic indicators of mortality in stroke patients. In: Sleep and Breathing. 2017 ; Vol. 21, No. 2. pp. 235-242.

Bibtex

@article{44c56e4a74974258811d1821edfad72e,
title = "Polysomnographic indicators of mortality in stroke patients",
abstract = "PURPOSE: The purpose of the study was to assess polysomnographic indicators of increased mortality risk in patients with stroke or a transient ischemic attack (TIA).METHODS: We performed polysomnographies in 63 acute stroke/TIA patients. Mortality data were collected from a national database after a 19-37-month follow-up period.RESULTS: Of the 57 stroke and 6 TIA patients, 9 stroke patients died during follow-up. All nine had moderate or severe sleep-related breathing disorders (SRBDs). Binarily divided, the group with the highest apnea hypopnea index (AHI) had an almost 10-fold higher mortality risk (hazard ratio (HR) 9.71; 95 % confidence interval (CI) 1.20-78.29; p = 0.033) compared to the patients with the lowest AHI. The patients with the longest versus shortest nocturnal wake time had a higher mortality (HR 8.78; 95 % CI 1.1-71.8; p = 0.0428). Lung disease increased mortality (HR 9.92; 95 % CI 2.00-49.23; p = 0.005), and there was a trend toward a higher mortality risk with atrial fibrillation/flutter (HR 3.63; 95 % CI 0.97-13.51; p = 0.055).CONCLUSIONS: In stroke patients, the AHI and nocturnal wake time are indicators of increased mortality risk. SRBDs in stroke patients should receive increased attention.",
keywords = "Journal Article",
author = "Ponsaing, {Laura B} and Iversen, {Helle K} and Poul Jennum",
year = "2017",
month = may,
doi = "10.1007/s11325-016-1387-z",
language = "English",
volume = "21",
pages = "235--242",
journal = "Sleep and Breathing",
issn = "1520-9512",
publisher = "Springer",
number = "2",

}

RIS

TY - JOUR

T1 - Polysomnographic indicators of mortality in stroke patients

AU - Ponsaing, Laura B

AU - Iversen, Helle K

AU - Jennum, Poul

PY - 2017/5

Y1 - 2017/5

N2 - PURPOSE: The purpose of the study was to assess polysomnographic indicators of increased mortality risk in patients with stroke or a transient ischemic attack (TIA).METHODS: We performed polysomnographies in 63 acute stroke/TIA patients. Mortality data were collected from a national database after a 19-37-month follow-up period.RESULTS: Of the 57 stroke and 6 TIA patients, 9 stroke patients died during follow-up. All nine had moderate or severe sleep-related breathing disorders (SRBDs). Binarily divided, the group with the highest apnea hypopnea index (AHI) had an almost 10-fold higher mortality risk (hazard ratio (HR) 9.71; 95 % confidence interval (CI) 1.20-78.29; p = 0.033) compared to the patients with the lowest AHI. The patients with the longest versus shortest nocturnal wake time had a higher mortality (HR 8.78; 95 % CI 1.1-71.8; p = 0.0428). Lung disease increased mortality (HR 9.92; 95 % CI 2.00-49.23; p = 0.005), and there was a trend toward a higher mortality risk with atrial fibrillation/flutter (HR 3.63; 95 % CI 0.97-13.51; p = 0.055).CONCLUSIONS: In stroke patients, the AHI and nocturnal wake time are indicators of increased mortality risk. SRBDs in stroke patients should receive increased attention.

AB - PURPOSE: The purpose of the study was to assess polysomnographic indicators of increased mortality risk in patients with stroke or a transient ischemic attack (TIA).METHODS: We performed polysomnographies in 63 acute stroke/TIA patients. Mortality data were collected from a national database after a 19-37-month follow-up period.RESULTS: Of the 57 stroke and 6 TIA patients, 9 stroke patients died during follow-up. All nine had moderate or severe sleep-related breathing disorders (SRBDs). Binarily divided, the group with the highest apnea hypopnea index (AHI) had an almost 10-fold higher mortality risk (hazard ratio (HR) 9.71; 95 % confidence interval (CI) 1.20-78.29; p = 0.033) compared to the patients with the lowest AHI. The patients with the longest versus shortest nocturnal wake time had a higher mortality (HR 8.78; 95 % CI 1.1-71.8; p = 0.0428). Lung disease increased mortality (HR 9.92; 95 % CI 2.00-49.23; p = 0.005), and there was a trend toward a higher mortality risk with atrial fibrillation/flutter (HR 3.63; 95 % CI 0.97-13.51; p = 0.055).CONCLUSIONS: In stroke patients, the AHI and nocturnal wake time are indicators of increased mortality risk. SRBDs in stroke patients should receive increased attention.

KW - Journal Article

U2 - 10.1007/s11325-016-1387-z

DO - 10.1007/s11325-016-1387-z

M3 - Journal article

C2 - 27475092

VL - 21

SP - 235

EP - 242

JO - Sleep and Breathing

JF - Sleep and Breathing

SN - 1520-9512

IS - 2

ER -

ID: 185716593