Required time delay from 99mTc-HMPAO injection to SPECT data acquisition: healthy subjects and patients with rCBF pattern
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
Required time delay from 99mTc-HMPAO injection to SPECT data acquisition: healthy subjects and patients with rCBF pattern. / Thomsen, Gerda; de Nijs, Robin; Hogh-Rasmussen, Esben; Frokjaer, Vibe; Svarer, Claus; Knudsen, Gitte M.
In: European Journal of Nuclear Medicine and Molecular Imaging, Vol. 35, No. 12, 01.12.2008, p. 2212-9.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Required time delay from 99mTc-HMPAO injection to SPECT data acquisition: healthy subjects and patients with rCBF pattern
AU - Thomsen, Gerda
AU - de Nijs, Robin
AU - Hogh-Rasmussen, Esben
AU - Frokjaer, Vibe
AU - Svarer, Claus
AU - Knudsen, Gitte M
PY - 2008/12/1
Y1 - 2008/12/1
N2 - Functional brain (99m)Tc-HMPAO single-photon emission computed tomography (SPECT) is a useful diagnostic tool for assessment of regional cerebral blood flow, particularly in dementia, cerebrovascular disease and epilepsy. Currently, the European and American Association of Nuclear Medicine Procedure Guidelines for Brain Perfusion SPET using (99m)Tc-labeled Radiopharmaceuticals recommend a time delay of 90 min between injection of (99m)Tc-HMPAO and data acquisition. This time delay is difficult to comply within the daily routine and present a problem, particularly with the elderly or demented patients. This study investigates in patients with perfusion deficits and in healthy subjects if the quality of the SPECT image is affected by lowering the time delay between (99m)Tc-HMPAO injection and data acquisition to 30 or 60 min.
AB - Functional brain (99m)Tc-HMPAO single-photon emission computed tomography (SPECT) is a useful diagnostic tool for assessment of regional cerebral blood flow, particularly in dementia, cerebrovascular disease and epilepsy. Currently, the European and American Association of Nuclear Medicine Procedure Guidelines for Brain Perfusion SPET using (99m)Tc-labeled Radiopharmaceuticals recommend a time delay of 90 min between injection of (99m)Tc-HMPAO and data acquisition. This time delay is difficult to comply within the daily routine and present a problem, particularly with the elderly or demented patients. This study investigates in patients with perfusion deficits and in healthy subjects if the quality of the SPECT image is affected by lowering the time delay between (99m)Tc-HMPAO injection and data acquisition to 30 or 60 min.
KW - Adult
KW - Aged
KW - Aged, 80 and over
KW - Case-Control Studies
KW - Cerebrovascular Circulation
KW - Female
KW - Health
KW - Humans
KW - Injections
KW - Male
KW - Middle Aged
KW - Principal Component Analysis
KW - Radioactivity
KW - Subtraction Technique
KW - Technetium Tc 99m Exametazime
KW - Time Factors
KW - Tomography, Emission-Computed, Single-Photon
U2 - 10.1007/s00259-008-0836-8
DO - 10.1007/s00259-008-0836-8
M3 - Journal article
C2 - 18542960
VL - 35
SP - 2212
EP - 2219
JO - European Journal of Nuclear Medicine and Molecular Imaging
JF - European Journal of Nuclear Medicine and Molecular Imaging
SN - 1619-7070
IS - 12
ER -
ID: 35305489