Slow oscillation electrical brain stimulation during waking promotes EEG theta activity and memory encoding

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Slow oscillation electrical brain stimulation during waking promotes EEG theta activity and memory encoding. / Kirov, Roumen; Weiss, Carsten; Siebner, Hartwig R; Born, Jan; Marshall, Lisa.

In: Proceedings of the National Academy of Science of the United States of America, Vol. 106, No. 36, 2009, p. 15460-5.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Kirov, R, Weiss, C, Siebner, HR, Born, J & Marshall, L 2009, 'Slow oscillation electrical brain stimulation during waking promotes EEG theta activity and memory encoding', Proceedings of the National Academy of Science of the United States of America, vol. 106, no. 36, pp. 15460-5. https://doi.org/10.1073/pnas.0904438106

APA

Kirov, R., Weiss, C., Siebner, H. R., Born, J., & Marshall, L. (2009). Slow oscillation electrical brain stimulation during waking promotes EEG theta activity and memory encoding. Proceedings of the National Academy of Science of the United States of America, 106(36), 15460-5. https://doi.org/10.1073/pnas.0904438106

Vancouver

Kirov R, Weiss C, Siebner HR, Born J, Marshall L. Slow oscillation electrical brain stimulation during waking promotes EEG theta activity and memory encoding. Proceedings of the National Academy of Science of the United States of America. 2009;106(36):15460-5. https://doi.org/10.1073/pnas.0904438106

Author

Kirov, Roumen ; Weiss, Carsten ; Siebner, Hartwig R ; Born, Jan ; Marshall, Lisa. / Slow oscillation electrical brain stimulation during waking promotes EEG theta activity and memory encoding. In: Proceedings of the National Academy of Science of the United States of America. 2009 ; Vol. 106, No. 36. pp. 15460-5.

Bibtex

@article{eb90e680aac711df928f000ea68e967b,
title = "Slow oscillation electrical brain stimulation during waking promotes EEG theta activity and memory encoding",
abstract = "The application of transcranial slow oscillation stimulation (tSOS; 0.75 Hz) was previously shown to enhance widespread endogenous EEG slow oscillatory activity when applied during a sleep period characterized by emerging endogenous slow oscillatory activity. Processes of memory consolidation typically occurring during this state of sleep were also enhanced. Here, we show that the same tSOS applied in the waking brain also induced an increase in endogenous EEG slow oscillations (0.4-1.2 Hz), although in a topographically restricted fashion. Applied during wakefulness tSOS, additionally, resulted in a marked and widespread increase in EEG theta (4-8 Hz) activity. During wake, tSOS did not enhance consolidation of memories when applied after learning, but improved encoding of hippocampus-dependent memories when applied during learning. We conclude that the EEG frequency and related memory processes induced by tSOS critically depend on brain state. In response to tSOS during wakefulness the brain transposes stimulation by responding preferentially with theta oscillations and facilitated encoding.",
author = "Roumen Kirov and Carsten Weiss and Siebner, {Hartwig R} and Jan Born and Lisa Marshall",
note = "Keywords: Adult; Analysis of Variance; Brain; Electric Stimulation Therapy; Germany; Humans; Learning; Memory; Oscillometry; Theta Rhythm; Wakefulness",
year = "2009",
doi = "10.1073/pnas.0904438106",
language = "English",
volume = "106",
pages = "15460--5",
journal = "Proceedings of the National Academy of Sciences of the United States of America",
issn = "0027-8424",
publisher = "The National Academy of Sciences of the United States of America",
number = "36",

}

RIS

TY - JOUR

T1 - Slow oscillation electrical brain stimulation during waking promotes EEG theta activity and memory encoding

AU - Kirov, Roumen

AU - Weiss, Carsten

AU - Siebner, Hartwig R

AU - Born, Jan

AU - Marshall, Lisa

N1 - Keywords: Adult; Analysis of Variance; Brain; Electric Stimulation Therapy; Germany; Humans; Learning; Memory; Oscillometry; Theta Rhythm; Wakefulness

PY - 2009

Y1 - 2009

N2 - The application of transcranial slow oscillation stimulation (tSOS; 0.75 Hz) was previously shown to enhance widespread endogenous EEG slow oscillatory activity when applied during a sleep period characterized by emerging endogenous slow oscillatory activity. Processes of memory consolidation typically occurring during this state of sleep were also enhanced. Here, we show that the same tSOS applied in the waking brain also induced an increase in endogenous EEG slow oscillations (0.4-1.2 Hz), although in a topographically restricted fashion. Applied during wakefulness tSOS, additionally, resulted in a marked and widespread increase in EEG theta (4-8 Hz) activity. During wake, tSOS did not enhance consolidation of memories when applied after learning, but improved encoding of hippocampus-dependent memories when applied during learning. We conclude that the EEG frequency and related memory processes induced by tSOS critically depend on brain state. In response to tSOS during wakefulness the brain transposes stimulation by responding preferentially with theta oscillations and facilitated encoding.

AB - The application of transcranial slow oscillation stimulation (tSOS; 0.75 Hz) was previously shown to enhance widespread endogenous EEG slow oscillatory activity when applied during a sleep period characterized by emerging endogenous slow oscillatory activity. Processes of memory consolidation typically occurring during this state of sleep were also enhanced. Here, we show that the same tSOS applied in the waking brain also induced an increase in endogenous EEG slow oscillations (0.4-1.2 Hz), although in a topographically restricted fashion. Applied during wakefulness tSOS, additionally, resulted in a marked and widespread increase in EEG theta (4-8 Hz) activity. During wake, tSOS did not enhance consolidation of memories when applied after learning, but improved encoding of hippocampus-dependent memories when applied during learning. We conclude that the EEG frequency and related memory processes induced by tSOS critically depend on brain state. In response to tSOS during wakefulness the brain transposes stimulation by responding preferentially with theta oscillations and facilitated encoding.

U2 - 10.1073/pnas.0904438106

DO - 10.1073/pnas.0904438106

M3 - Journal article

C2 - 19706399

VL - 106

SP - 15460

EP - 15465

JO - Proceedings of the National Academy of Sciences of the United States of America

JF - Proceedings of the National Academy of Sciences of the United States of America

SN - 0027-8424

IS - 36

ER -

ID: 21458617