Tools to explore neuroplasticity in humans: Combining interventional neurophysiology with functional and structural magnetic resonance imaging and spectroscopy

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

Standard

Tools to explore neuroplasticity in humans : Combining interventional neurophysiology with functional and structural magnetic resonance imaging and spectroscopy. / Christiansen, Lasse; Siebner, Hartwig Roman.

Handbook of Clinical Neurology. Vol. 184 Elsevier, 2022. p. 105-119 (Handbook of Clinical Neurology, Vol. 184).

Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

Harvard

Christiansen, L & Siebner, HR 2022, Tools to explore neuroplasticity in humans: Combining interventional neurophysiology with functional and structural magnetic resonance imaging and spectroscopy. in Handbook of Clinical Neurology. vol. 184, Elsevier, Handbook of Clinical Neurology, vol. 184, pp. 105-119. https://doi.org/10.1016/B978-0-12-819410-2.00032-1

APA

Christiansen, L., & Siebner, H. R. (2022). Tools to explore neuroplasticity in humans: Combining interventional neurophysiology with functional and structural magnetic resonance imaging and spectroscopy. In Handbook of Clinical Neurology (Vol. 184, pp. 105-119). Elsevier. Handbook of Clinical Neurology Vol. 184 https://doi.org/10.1016/B978-0-12-819410-2.00032-1

Vancouver

Christiansen L, Siebner HR. Tools to explore neuroplasticity in humans: Combining interventional neurophysiology with functional and structural magnetic resonance imaging and spectroscopy. In Handbook of Clinical Neurology. Vol. 184. Elsevier. 2022. p. 105-119. (Handbook of Clinical Neurology, Vol. 184). https://doi.org/10.1016/B978-0-12-819410-2.00032-1

Author

Christiansen, Lasse ; Siebner, Hartwig Roman. / Tools to explore neuroplasticity in humans : Combining interventional neurophysiology with functional and structural magnetic resonance imaging and spectroscopy. Handbook of Clinical Neurology. Vol. 184 Elsevier, 2022. pp. 105-119 (Handbook of Clinical Neurology, Vol. 184).

Bibtex

@inbook{05204e599ee8438da28393f097fd0720,
title = "Tools to explore neuroplasticity in humans: Combining interventional neurophysiology with functional and structural magnetic resonance imaging and spectroscopy",
abstract = "This chapter summarizes how brain imaging can be used in combination with non-invasive transcranial stimulation to probe and induce neuroplasticity in the human brain. We aim to give a conceptual account and highlight exemplary studies. We showcase the scientific and clinical potentials of studies focusing on the combination of transcranial magnetic stimulation (TMS) with Magnetic Resonance Imaging (MRI) or Magnetic Resonance Spectroscopy (MRS). MRI and MRS can be used before brain stimulation to identify target networks and loci but also to inform individual dosing. After a brain stimulation session, MRI and MRS can be used to pinpoint how the stimulation protocol alters brain function, structure, or metabolism and relate these after-effects to behavioral and clinical outcomes. Complementing these “offline” approaches, TMS can also be applied “online” during MRI or MRS to delineate how stimulation acutely engages the stimulated brain regions and networks. In this case, it is critical to account for confounds introduced by off-target stimulation of peripheral structures of the nervous system that may not only confound MR-based readouts but also induce neuroplastic phenomena.",
keywords = "Magnetic resonance imaging, Magnetic resonance spectroscopy, Neuroimaging, Non-invasive transcranial stimulation, Plasticity, Transcranial magnetic stimulation",
author = "Lasse Christiansen and Siebner, {Hartwig Roman}",
note = "Publisher Copyright: {\textcopyright} 2022 Elsevier B.V.",
year = "2022",
doi = "10.1016/B978-0-12-819410-2.00032-1",
language = "English",
isbn = "978-0-12-819410-2",
volume = "184",
series = "Handbook of Clinical Neurology",
publisher = "Elsevier",
pages = "105--119",
booktitle = "Handbook of Clinical Neurology",
address = "Netherlands",

}

RIS

TY - CHAP

T1 - Tools to explore neuroplasticity in humans

T2 - Combining interventional neurophysiology with functional and structural magnetic resonance imaging and spectroscopy

AU - Christiansen, Lasse

AU - Siebner, Hartwig Roman

N1 - Publisher Copyright: © 2022 Elsevier B.V.

PY - 2022

Y1 - 2022

N2 - This chapter summarizes how brain imaging can be used in combination with non-invasive transcranial stimulation to probe and induce neuroplasticity in the human brain. We aim to give a conceptual account and highlight exemplary studies. We showcase the scientific and clinical potentials of studies focusing on the combination of transcranial magnetic stimulation (TMS) with Magnetic Resonance Imaging (MRI) or Magnetic Resonance Spectroscopy (MRS). MRI and MRS can be used before brain stimulation to identify target networks and loci but also to inform individual dosing. After a brain stimulation session, MRI and MRS can be used to pinpoint how the stimulation protocol alters brain function, structure, or metabolism and relate these after-effects to behavioral and clinical outcomes. Complementing these “offline” approaches, TMS can also be applied “online” during MRI or MRS to delineate how stimulation acutely engages the stimulated brain regions and networks. In this case, it is critical to account for confounds introduced by off-target stimulation of peripheral structures of the nervous system that may not only confound MR-based readouts but also induce neuroplastic phenomena.

AB - This chapter summarizes how brain imaging can be used in combination with non-invasive transcranial stimulation to probe and induce neuroplasticity in the human brain. We aim to give a conceptual account and highlight exemplary studies. We showcase the scientific and clinical potentials of studies focusing on the combination of transcranial magnetic stimulation (TMS) with Magnetic Resonance Imaging (MRI) or Magnetic Resonance Spectroscopy (MRS). MRI and MRS can be used before brain stimulation to identify target networks and loci but also to inform individual dosing. After a brain stimulation session, MRI and MRS can be used to pinpoint how the stimulation protocol alters brain function, structure, or metabolism and relate these after-effects to behavioral and clinical outcomes. Complementing these “offline” approaches, TMS can also be applied “online” during MRI or MRS to delineate how stimulation acutely engages the stimulated brain regions and networks. In this case, it is critical to account for confounds introduced by off-target stimulation of peripheral structures of the nervous system that may not only confound MR-based readouts but also induce neuroplastic phenomena.

KW - Magnetic resonance imaging

KW - Magnetic resonance spectroscopy

KW - Neuroimaging

KW - Non-invasive transcranial stimulation

KW - Plasticity

KW - Transcranial magnetic stimulation

U2 - 10.1016/B978-0-12-819410-2.00032-1

DO - 10.1016/B978-0-12-819410-2.00032-1

M3 - Book chapter

C2 - 35034728

AN - SCOPUS:85122813695

SN - 978-0-12-819410-2

VL - 184

T3 - Handbook of Clinical Neurology

SP - 105

EP - 119

BT - Handbook of Clinical Neurology

PB - Elsevier

ER -

ID: 290527896