Automated Quantification of Macular Vasculature Changes from OCTA Images of Hematologic Patients
Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
Standard
Automated Quantification of Macular Vasculature Changes from OCTA Images of Hematologic Patients. / Engberg, Astrid M.E.; Amini, Abdullah; Willerslev, Anne; Larsen, Michael; Sander, Birgit; Kessel, Line; Dahl, Anders B.; Dahl, Vedrana A.
2020 IEEE 17th International Symposium on Biomedical Imaging. IEEE, 2020. p. 1987-1991 9098441 (Proceedings - International Symposium on Biomedical Imaging, Vol. 2020-April).Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - GEN
T1 - Automated Quantification of Macular Vasculature Changes from OCTA Images of Hematologic Patients
AU - Engberg, Astrid M.E.
AU - Amini, Abdullah
AU - Willerslev, Anne
AU - Larsen, Michael
AU - Sander, Birgit
AU - Kessel, Line
AU - Dahl, Anders B.
AU - Dahl, Vedrana A.
PY - 2020
Y1 - 2020
N2 - Abnormal blood compositions can lead to abnormal blood flow which can influence the macular vasculature. Optical coherence tomography angiography (OCTA) makes it possible to study the macular vasculature and potential vascular abnormalities induced by hematological disorders. Here, we investigate vascular changes in control subjects and in hematologic patients before and after treatment. Since these changes are small, they are difficult to notice in the OCTA images. To quantify vascular changes, we propose a method for combined capillary registration, dictionary-based segmentation and local density estimation. Using this method, we investigate three patients and five controls, and our results show that we can detect small changes in the vasculature in patients with large changes in blood composition.
AB - Abnormal blood compositions can lead to abnormal blood flow which can influence the macular vasculature. Optical coherence tomography angiography (OCTA) makes it possible to study the macular vasculature and potential vascular abnormalities induced by hematological disorders. Here, we investigate vascular changes in control subjects and in hematologic patients before and after treatment. Since these changes are small, they are difficult to notice in the OCTA images. To quantify vascular changes, we propose a method for combined capillary registration, dictionary-based segmentation and local density estimation. Using this method, we investigate three patients and five controls, and our results show that we can detect small changes in the vasculature in patients with large changes in blood composition.
KW - Microvasculature
KW - OCTA
KW - Quantification
U2 - 10.1109/ISBI45749.2020.9098441
DO - 10.1109/ISBI45749.2020.9098441
M3 - Article in proceedings
AN - SCOPUS:85085861908
T3 - Proceedings - International Symposium on Biomedical Imaging
SP - 1987
EP - 1991
BT - 2020 IEEE 17th International Symposium on Biomedical Imaging
PB - IEEE
T2 - 17th IEEE International Symposium on Biomedical Imaging, ISBI 2020
Y2 - 3 April 2020 through 7 April 2020
ER -
ID: 251582788