Non-invasive bleaching of the human lens by femtosecond laser photolysis
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Non-invasive bleaching of the human lens by femtosecond laser photolysis. / Kessel, Line; Eskildsen, Lars; Poel, Mike van der; Larsen, Michael.
In: P L o S One, Vol. 5, No. 3, 01.01.2010, p. e9711.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Non-invasive bleaching of the human lens by femtosecond laser photolysis
AU - Kessel, Line
AU - Eskildsen, Lars
AU - Poel, Mike van der
AU - Larsen, Michael
PY - 2010/1/1
Y1 - 2010/1/1
N2 - Globally, cataract is the leading cause of blindness and impaired vision. Cataract surgery is an attractive treatment option but it remains unavailable in sufficient quantity for the vast majority of the world population living in areas without access to specialized health care. Reducing blindness from cataract requires solutions that can be applied outside operating theatres. Cataract is a protein conformational disease characterized by accumulation of light absorbing, fluorescent and scattering protein aggregates. The aim of the study was to investigate whether these compounds were susceptible to photobleaching by a non-invasive procedure and whether this would lead to optical rejuvenation of the lens.
AB - Globally, cataract is the leading cause of blindness and impaired vision. Cataract surgery is an attractive treatment option but it remains unavailable in sufficient quantity for the vast majority of the world population living in areas without access to specialized health care. Reducing blindness from cataract requires solutions that can be applied outside operating theatres. Cataract is a protein conformational disease characterized by accumulation of light absorbing, fluorescent and scattering protein aggregates. The aim of the study was to investigate whether these compounds were susceptible to photobleaching by a non-invasive procedure and whether this would lead to optical rejuvenation of the lens.
U2 - http://dx.doi.org/10.1371/journal.pone.0009711
DO - http://dx.doi.org/10.1371/journal.pone.0009711
M3 - Journal article
VL - 5
SP - e9711
JO - PLoS ONE
JF - PLoS ONE
SN - 1932-6203
IS - 3
ER -
ID: 34072358