A mechanoelectrical mechanism for detection of sound envelopes in the hearing organ

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

A mechanoelectrical mechanism for detection of sound envelopes in the hearing organ. / Nuttall, Alfred L; Ricci, Anthony J; Burwood, George; Harte, James M; Stenfelt, Stefan; Cayé-Thomasen, Per; Ren, Tianying; Ramamoorthy, Sripriya; Zhang, Yuan; Wilson, Teresa; Lunner, Thomas; Moore, Brian C J; Fridberger, Anders.

In: Nature Communications, Vol. 9, 4175, 2018.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Nuttall, AL, Ricci, AJ, Burwood, G, Harte, JM, Stenfelt, S, Cayé-Thomasen, P, Ren, T, Ramamoorthy, S, Zhang, Y, Wilson, T, Lunner, T, Moore, BCJ & Fridberger, A 2018, 'A mechanoelectrical mechanism for detection of sound envelopes in the hearing organ', Nature Communications, vol. 9, 4175. https://doi.org/10.1038/s41467-018-06725-w

APA

Nuttall, A. L., Ricci, A. J., Burwood, G., Harte, J. M., Stenfelt, S., Cayé-Thomasen, P., Ren, T., Ramamoorthy, S., Zhang, Y., Wilson, T., Lunner, T., Moore, B. C. J., & Fridberger, A. (2018). A mechanoelectrical mechanism for detection of sound envelopes in the hearing organ. Nature Communications, 9, [4175]. https://doi.org/10.1038/s41467-018-06725-w

Vancouver

Nuttall AL, Ricci AJ, Burwood G, Harte JM, Stenfelt S, Cayé-Thomasen P et al. A mechanoelectrical mechanism for detection of sound envelopes in the hearing organ. Nature Communications. 2018;9. 4175. https://doi.org/10.1038/s41467-018-06725-w

Author

Nuttall, Alfred L ; Ricci, Anthony J ; Burwood, George ; Harte, James M ; Stenfelt, Stefan ; Cayé-Thomasen, Per ; Ren, Tianying ; Ramamoorthy, Sripriya ; Zhang, Yuan ; Wilson, Teresa ; Lunner, Thomas ; Moore, Brian C J ; Fridberger, Anders. / A mechanoelectrical mechanism for detection of sound envelopes in the hearing organ. In: Nature Communications. 2018 ; Vol. 9.

Bibtex

@article{bbfafe34a1594368b3e4c0ee8d1b4639,
title = "A mechanoelectrical mechanism for detection of sound envelopes in the hearing organ",
abstract = "To understand speech, the slowly varying outline, or envelope, of the acoustic stimulus is used to distinguish words. A small amount of information about the envelope is sufficient for speech recognition, but the mechanism used by the auditory system to extract the envelope is not known. Several different theories have been proposed, including envelope detection by auditory nerve dendrites as well as various mechanisms involving the sensory hair cells. We used recordings from human and animal inner ears to show that the dominant mechanism for envelope detection is distortion introduced by mechanoelectrical transduction channels. This electrical distortion, which is not apparent in the sound-evoked vibrations of the basilar membrane, tracks the envelope, excites the auditory nerve, and transmits information about the shape of the envelope to the brain.",
keywords = "Acoustic Stimulation, Adult, Animals, Basilar Membrane/physiology, Biomechanical Phenomena, Cochlea/physiology, Electricity, Female, Hearing/physiology, Humans, Male, Middle Aged, Organ of Corti/physiology, Rats, Sound",
author = "Nuttall, {Alfred L} and Ricci, {Anthony J} and George Burwood and Harte, {James M} and Stefan Stenfelt and Per Cay{\'e}-Thomasen and Tianying Ren and Sripriya Ramamoorthy and Yuan Zhang and Teresa Wilson and Thomas Lunner and Moore, {Brian C J} and Anders Fridberger",
year = "2018",
doi = "10.1038/s41467-018-06725-w",
language = "English",
volume = "9",
journal = "Nature Communications",
issn = "2041-1723",
publisher = "nature publishing group",

}

RIS

TY - JOUR

T1 - A mechanoelectrical mechanism for detection of sound envelopes in the hearing organ

AU - Nuttall, Alfred L

AU - Ricci, Anthony J

AU - Burwood, George

AU - Harte, James M

AU - Stenfelt, Stefan

AU - Cayé-Thomasen, Per

AU - Ren, Tianying

AU - Ramamoorthy, Sripriya

AU - Zhang, Yuan

AU - Wilson, Teresa

AU - Lunner, Thomas

AU - Moore, Brian C J

AU - Fridberger, Anders

PY - 2018

Y1 - 2018

N2 - To understand speech, the slowly varying outline, or envelope, of the acoustic stimulus is used to distinguish words. A small amount of information about the envelope is sufficient for speech recognition, but the mechanism used by the auditory system to extract the envelope is not known. Several different theories have been proposed, including envelope detection by auditory nerve dendrites as well as various mechanisms involving the sensory hair cells. We used recordings from human and animal inner ears to show that the dominant mechanism for envelope detection is distortion introduced by mechanoelectrical transduction channels. This electrical distortion, which is not apparent in the sound-evoked vibrations of the basilar membrane, tracks the envelope, excites the auditory nerve, and transmits information about the shape of the envelope to the brain.

AB - To understand speech, the slowly varying outline, or envelope, of the acoustic stimulus is used to distinguish words. A small amount of information about the envelope is sufficient for speech recognition, but the mechanism used by the auditory system to extract the envelope is not known. Several different theories have been proposed, including envelope detection by auditory nerve dendrites as well as various mechanisms involving the sensory hair cells. We used recordings from human and animal inner ears to show that the dominant mechanism for envelope detection is distortion introduced by mechanoelectrical transduction channels. This electrical distortion, which is not apparent in the sound-evoked vibrations of the basilar membrane, tracks the envelope, excites the auditory nerve, and transmits information about the shape of the envelope to the brain.

KW - Acoustic Stimulation

KW - Adult

KW - Animals

KW - Basilar Membrane/physiology

KW - Biomechanical Phenomena

KW - Cochlea/physiology

KW - Electricity

KW - Female

KW - Hearing/physiology

KW - Humans

KW - Male

KW - Middle Aged

KW - Organ of Corti/physiology

KW - Rats

KW - Sound

U2 - 10.1038/s41467-018-06725-w

DO - 10.1038/s41467-018-06725-w

M3 - Journal article

C2 - 30302006

VL - 9

JO - Nature Communications

JF - Nature Communications

SN - 2041-1723

M1 - 4175

ER -

ID: 216471107