Survival and characteristics of pediatric salivary gland cancer: A systematic review and meta-analysis
Research output: Contribution to journal › Review › Research › peer-review
A systematic search of PubMed, EMBASE, and the Cochrane Library for studies from 2000 to 2017 including children aged 0-19 with salivary gland cancer was performed. In 19 studies, 749 children (median age of 14.2 years, female to male ratio of 1.4:1) were included; 72% had parotid tumors and 95% underwent surgery, of whom 65% had surgery alone and 24% with adjuvant radiotherapy. Low-grade and stage mucoepidermoid carcinoma were the most frequent cancer. The 5-year overall- and disease-free survival was 94% and 83%. Recurrence was observed in 20% at a median of 1.1 years from diagnosis.
Original language | English |
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Article number | e27543 |
Journal | Pediatric Blood & Cancer |
Volume | 66 |
Issue number | 3 |
Number of pages | 8 |
ISSN | 1545-5009 |
DOIs | |
Publication status | Published - 2019 |
ID: 224551809