Niels Erik Skakkebæk
Affiliate Professor
- 2019
- Published
Developmental origins of testicular germ cell tumours (TGCT)
Meyts, E. R., Jørgensen, A., Jørgensen, N., Almstrup, Kristian & Skakkebæk, Niels Erik, Sep 2019, In: European Urology Supplements. 18, 4, p. 11Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Central Precocious Puberty in two Boys with Prader-Willi Syndrome on Growth Hormone Treatment
Monai, E., Johansen, A., Clasen-Linde, E., Rajpert-De Meyts, E., Skakkebæk, Niels Erik, Main, Katharina Maria, Jørgensen, A. & Jensen, R. B., 2019, In: AACE Clinical Case Reports. 5, 6, p. e352-e356Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterisation and localisation of the endocannabinoid system components in the adult human testis
Nielsen, J. E., Rolland, A. D., Rajpert-De Meyts, E., Janfelt, Christian, Jørgensen, A., Winge, S. B., Kristensen, D. M., Juul, Anders, Chalmel, F., Jégou, B. & Skakkebæk, Niels Erik, 2019, In: Scientific Reports. 9, 1, 14 p., 12866.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anogenital distance is associated with semen quality but not reproductive hormones in 1106 young men from the general population
Priskorn, L., Bang, A. K., Nordkap, L., Krause, M., Mendiola, J., Jensen, T. K., Juul, Anders, Skakkebæk, Niels Erik, Swan, S. H. & Jørgensen, Niklas Rye, 1 Jan 2019, In: Human reproduction (Oxford, England). 34, 1, p. 12-24 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High maternal age at first and subsequent child births in Denmark in the mid-1800s-Letter to the editor
Priskorn, L., Dahl, C. L., Pihl, A. S., Skakkebæk, Niels Erik & Juul, Anders, Oct 2019, In: European Journal of Obstetrics & Gynecology and Reproductive Biology. 241, p. 137-138 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Semen quality of young men in Switzerland: a nationwide cross-sectional population-based study
Rahban, R., Priskorn, L., Senn, A., Stettler, E., Galli, F., Vargas, J., Van den Bergh, M., Fusconi, A., Garlantezec, R., Jensen, T. K., Multigner, L., Skakkebæk, Niels Erik, Germond, M., Jørgensen, N., Nef, S. & The NICER Working Group, T. N. W. G., 2019, In: Andrology. 7, 6, p. 818-826Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Medium-throughput Screening Assays for Assessment of Effects on Ca2+-Signaling and Acrosome Reaction in Human Sperm
Rehfeld, Anders Aagaard, Palme, D. L. E., Almstrup, Kristian, Juul, Anders & Skakkebæk, Niels Erik, 2019, In: Journal of Visualized Experiments. 145, p. e59212Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Medium-throughput Screening Assays for Assessment of Effects on Ca2+-Signaling and Acrosome Reaction in Human Sperm
Rehfeld, A., Egeberg Palme, D. L., Almstrup, K., Juul, Anders & Skakkebæk, Niels Erik, 1 Mar 2019, In: Journal of visualized experiments : JoVE. 145, 9 p., e59212.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An update on semen quality among young Finnish men and comparison with Danish data
Rodprasert, W., Virtanen, H. E., Sadov, S., Perheentupa, A., Skakkebæk, Niels Erik, Jørgensen, N. & Toppari, J., 2019, In: Andrology. 7, 1, p. 15-23 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Populations, decreasing fertility, and reproductive health
Skakkebæk, Niels Erik, Jørgensen, N., Andersson, A., Juul, Anders, Main, Katharina Maria, Jensen, T. K. & Toppari, J., 13 Apr 2019, In: Lancet Oncology. 393, 10180, p. 1500-1501 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- 2018
- Published
Is the FSHR 2039A>G variant associated with susceptibility to testicular germ cell cancer?
Bang, A. K., Busch, A. S., Almstrup, Kristian, Gromoll, J., Kliesch, S., Rajpert-De Meyts, E., Skakkebæk, Niels Erik, Juul, Anders, Tüttelmann, F. & Jørgensen, N., 2018, In: Andrology. 6, 1, p. 176-183 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synergistic activation of CatSper Ca2+ channels in human sperm by oviductal ligands and endocrine disrupting chemicals
Brenker, C., Rehfeld, Anders Aagaard, Schiffer, C., Kierzek, M., Kaupp, U. B., Skakkebæk, Niels Erik & Strünker, T., 2018, In: Human Reproduction. 33, 10, p. 1915-1923 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Viable acrosome-intact human spermatozoa in the ejaculate as a marker of semen quality and fertility status
Egeberg Palme, D. L., Rehfeld, Anders Aagaard, Bang, A. K., Nikolova, K. A., Kjærulff, S., Petersen, M. R., Jeppesen, J. V., Glensbjerg, M., Juul, Anders, Skakkebæk, Niels Erik, Ziebe, S., Jørgensen, N. & Almstrup, Kristian, 2018, In: Human Reproduction. 33, 3, p. 361-371 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The possible impact of antenatal exposure to ubiquitous phthalates upon male reproductive function at 20 years of age
Hart, R. J., Frederiksen, H., Doherty, D. A., Keelan, J. A., Skakkebæk, Niels Erik, Minaee, N. S., McLachlan, R., Newnham, J. P., Dickinson, J. E., Pennell, C. E., Norman, R. J. & Main, Katharina Maria, 2018, In: Frontiers in Endocrinology. 9, JUN, 11 p., 288.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Individual testosterone decline and future mortality risk in men
Holmboe, S. A., Skakkebæk, Niels Erik, Juul, Anders, Scheike, Thomas, Jensen, T. K., Linneberg, Allan René, Thuesen, B. H. & Andersson, A., Jan 2018, In: European Journal of Endocrinology. 178, p. 121-128Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nodal Signaling Regulates Germ Cell Development and Establishment of Seminiferous Cords in the Human Fetal Testis
Jørgensen, A., Macdonald, J., Nielsen, J. E., Kilcoyne, K. R., Perlman, S., Lundvall, L., Langhoff Thuesen, L., Hare, Kristine Juul, Frederiksen, H., Andersson, A., Skakkebæk, Niels Erik, Juul, Anders, Sharpe, R. M., Rajpert-De Meyts, E. & Mitchell, R. T., 13 Nov 2018, In: Cell Reports. 25, 7, p. 1924-1937.e4Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postnatal Changes in Testicular Position Are Associated With IGF-I and Function of Sertoli and Leydig Cells
Koskenniemi, J. J., Virtanen, H. E., Wohlfahrt-Veje, C., Löyttyniemi, E., Skakkebæk, Niels Erik, Juul, Anders, Andersson, A., Main, Katharina Maria & Toppari, J., 2018, In: The Journal of clinical endocrinology and metabolism. 103, 4, p. 1429-1437Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Presence of benzophenones commonly used as UV filters and absorbers in paired maternal and fetal samples
Krause, M., Frederiksen, H., Sundberg, K., Jørgensen, F. S., Jensen, L. N., Nørgaard, P., Jørgensen, C., Ertberg, P., Juul, Anders, Drzewiecki, K. T., Skakkebæk, Niels Erik & Andersson, A. M., 2018, In: Environment International. 110, p. 51-60 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maternal exposure to UV filters: Associations with maternal thyroid hormones, IGF-I/IGFBP3 and birth outcomes
Krause, M., Frederiksen, H., Sundberg, K., Jørgensen, Finn Stener, Jensen, L. N., Nørgaard, P., Jørgensen, C., Ertberg, P., Petersen, Jørgen Holm, Feldt-Rasmussen, Ulla, Juul, Anders, Drzewiecki, K. T., Skakkebæk, Niels Erik & Andersson, A. M., 1 Feb 2018, In: Endocrine Connections. 7, 2, p. 334-346 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of in Utero Persistent Organic Pollutant Exposure with Placental Thyroid Hormones
Li, Z. M., Hernandez-Moreno, D., Main, Katharina Maria, Skakkebæk, Niels Erik, Kiviranta, H., Toppari, J., Feldt-Rasmussen, Ulla, Shen, H., Schramm, K. W. & De Angelis, M., 2018, In: Endocrinology. 159, 10, p. 3473-3481 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determination of thyroid hormones in placenta using isotope-dilution liquid chromatography quadrupole time-of-flight mass spectrometry
Li, Z., Giesert, F., Vogt-Weisenhorn, D., Main, Katharina Maria, Skakkebæk, Niels Erik, Kiviranta, H., Toppari, J., Feldt-Rasmussen, Ulla, Shen, H., Schramm, K. & De Angelis, M., 2018, In: Journal of Chromatography A. 1534, p. 85-92Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A crossover-crossback prospective study of dibutyl-phthalate exposure from mesalamine medications and serum reproductive hormones in men
Nassan, F. L., Coull, B. A., Skakkebæk, Niels Erik, Andersson, A., Williams, M. A., Mínguez-Alarcón, L., Krawetz, S. A., Hall, J. E., Hait, E. J., Korzenik, J. R., Ford, J. B., Moss, A. C. & Hauser, R., 2018, In: Environmental Research. 160, p. 121-131 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Parental occupational exposure to solvents and heavy metals and risk of developing testicular germ cell tumors in sons (NORD-TEST Denmark)
Olsson, A., Togawa, K., Schüz, J., Le Cornet, C., Fervers, B., Oksbjerg Dalton, S., Pukkala, E., Maria Feychting, M. F., Skakkebæk, Niels Erik & Hansen, J., 2018, In: Scandinavian Journal of Work, Environment & Health. 44, 6, p. 658-669Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Average sperm count remains unchanged despite reduction in maternal smoking: results from a large cross-sectional study with annual investigations over 21 years
Priskorn, L., Nordkap, L., Bang, A. K., Krause, M., Holmboe, S. A., Egeberg Palme, D. L., Winge, S. B., Mørup, N., Carlsen, E., Joensen, Ulla Nordström, Blomberg Jensen, M., Main, Katharina Maria, Juul, Anders, Skakkebæk, Niels Erik, Jensen, T. K. & Jørgensen, N., 2018, In: Human Reproduction. 33, 6, p. 998-1008 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anogenital distance as a phenotypic signature through infancy
Priskorn, L., Petersen, Jørgen Holm, Jørgensen, N., Kyhl, H. B., Andersen, M. S., Main, Katharina Maria, Andersson, A., Skakkebæk, Niels Erik & Jensen, T. K., 2018, In: Pediatric Research. 83, 3, p. 573-579 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
EDC IMPACT: Chemical UV filters can affect human sperm function in a progesterone-like manner
Rehfeld, Anders Aagaard, Egeberg, D., Almstrup, Kristian, Petersen, Jørgen Holm, Dissing, Steen & Skakkebæk, Niels Erik, 2018, In: Endocrine Connections. 7, 1, p. 16-25Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantification of the Leydig cell compartment in testicular biopsies and association with biochemical Leydig cell dysfunction in testicular cancer survivors
Tarsitano, M. G., Bandak, M., Jørgensen, N., Skakkebæk, Niels Erik, Juul, Anders, Lenzi, A., Daugaard, G. & Rajpert-De Meyts, E., 2018, In: Andrology. 6, 5, p. 748-755 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli- and Leydig cells
Winge, S. B., Dalgaard, M. D., Belling, K. G., Jensen, J. M., Nielsen, J. E., Aksglaede, L., Schierup, M. H., Brunak, Søren, Skakkebæk, Niels Erik, Juul, Anders, Rajpert-De Meyts, E. & Almstrup, Kristian, 2018, In: Cell Death & Disease. 9, 6, 14 p., 586.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Assumed non-persistent environmental chemicals in human adipose tissue; matrix stability and correlation with levels measured in urine and serum
Artacho-Cordón, F., Arrebola, J. P., Nielsen, O., Hernández, P., Skakkebæk, Niels Erik, Fernández, M. F., Andersson, A. M., Olea, N. & Frederiksen, H., Jul 2017, In: Environmental Research. 156, p. 120-127 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Klinefelter syndrome comorbidities linked to increased X chromosome gene dosage and altered protein interactome activity
Belling, K., Russo, F., Jensen, A. B., Dalgaard, M. D., Westergaard, D., Rajpert-De Meyts, E., Skakkebæk, Niels Erik, Juul, Anders & Brunak, Søren, 1 Apr 2017, In: Human Molecular Genetics. 26, 7, p. 1219-1229 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reply to Eugenio Ventimiglia, Francesco Montorsi, and Andrea Salonia's Letter to the Editor re: Jakob Damsgaard, Ulla N. Joensen, Elisabeth Carlsen, et al. Varicocele Is Associated with Impaired Semen Quality and Reproductive Hormone Levels: A Study of 7035 Healthy Young Men from Six European Countries. Eur Urol 2016;70:1019-29
Damsgaard, J., Joensen, Ulla Nordström, Carlsen, E., Erenpreiss, J., Jensen, M. B., Matulevicius, V., Zilaitiene, B., Olesen, I. A., Perheentupa, A., Punab, M., Salzbrunn, A., Toppari, J., Virtanen, H. E., Juul, Anders, Skakkebæk, Niels Erik & Jørgensen, N., 2017, In: European Urology. 71, 2, p. e71-e72Research output: Contribution to journal › Comment/debate › Research
- Published
Validation of image cytometry for sperm concentration measurement: Comparison with manual counting of 4010 human semen samples
Egeberg Palme, D. L., Johannsen, T. H., Petersen, Jørgen Holm, Skakkebæk, Niels Erik, Juul, Anders, Jørgensen, N. & Almstrup, Kristian, 2017, In: Clinica Chimica Acta. 468, p. 114-119 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
UV filters analyzed by isotope diluted TurboFlow-LC-MS/MS in urine from Danish children and adolescents
Frederiksen, H., Nielsen, O., Skakkebæk, Niels Erik, Juul, Anders & Andersson, A., Mar 2017, In: International Journal of Hygiene and Environmental Health. 220, 2, Part A, p. 244-253 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of marital status on testosterone levels-A ten year follow-up of 1113 men
Holmboe, S. A., Priskorn, L., Jørgensen, N., Skakkebæk, Niels Erik, Linneberg, Allan René, Juul, Anders & Andersson, A., 2017, In: Psychoneuroendocrinology. 80, p. 155-161 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exposure to phenols, parabens and UV filters: Associations with loss-of-function mutations in the filaggrin gene in men from the general population
Joensen, U. N., Jørgensen, N., Thyssen, Jacob Pontoppidan, Petersen, Jørgen Holm, Szecsi, P. B., Stender, S., Andersson, A. M., Skakkebæk, Niels Erik & Frederiksen, H., 2017, In: Environment International. 105, p. 105-111Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chromosome-wise Protein Interaction Patterns and Their Impact on Functional Implications of Large-Scale Genomic Aberrations
Kirk, I. K., Weinhold, N., Belling, K., Skakkebæk, Niels Erik, Jensen, T. S., Leffers, H., Juul, Anders & Brunak, Søren, 22 Mar 2017, In: Cell Systems. 4, 3, 11 p., 357-364.e3.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exposure to UV filters during summer and winter in Danish kindergarten children
Krause, M., Andersson, A., Skakkebæk, Niels Erik & Frederiksen, H., Feb 2017, In: Environment International. 99, p. 177-184 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maternal use of mild analgesics during pregnancy associated with reduced anogenital distance in sons: a cohort study of 1027 mother-child pairs
Lind, D. V., Main, Katharina Maria, Kyhl, H. B., Kristensen, D. M., Toppari, J., Andersen, H. R., Skovsager Andersen, M., Skakkebæk, Niels Erik & Jensen, T. K., 2017, In: Human Reproduction. 32, 1, p. 223-231 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of global gene expression profiles of microdissected human foetal Leydig cells with their normal and hyperplastic adult equivalents
Lottrup, G., Belling, K., Leffers, H., Nielsen, J. E., Dalgaard, M. D., Juul, Anders, Skakkebæk, Niels Erik, Brunak, Søren & Meyts, E. R., 1 May 2017, In: Molecular Human Reproduction. 23, 5, p. 339-354 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prenatal exposure to antifungal medication may change anogenital distance in male offspring: a preliminary study
Mogensen, D. M., Pihl, M. B., Skakkebæk, Niels Erik, Andersen, H. R., Juul, Anders, Kyhl, H. B., Swan, S., Kristensen, D. M., Andersen, M. S., Lind, D. V. & Jensen, T. K., 2017, In: Environmental Health. 16, 8 p., 68.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Germ cell neoplasia in situ and preserved fertility despite suppressed gonadotropins in a patient with testotoxicosis
Mortensen, L. J., Jensen, M. B., Christiansen, P., Rønholt, A. M., Jørgensen, A., Frederiksen, H., Nielsen, J. E., Loya, Anand Chainsukh, Grønkær Toft, B., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Juul, Anders, 2017, In: Journal of Clinical Endocrinology and Metabolism. 102, 12, p. 4411-4416 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Personal Care Product Use in Men and Urinary Concentrations of Select Phthalate Metabolites and Parabens: Results from the Environment And Reproductive Health (EARTH) Study
Nassan, F. L., Coull, B. A., Gaskins, A. J., Williams, M. A., Skakkebæk, Niels Erik, Ford, J. B., Ye, X., Calafat, A. M., Braun, J. M. & Hauser, R., 2017, In: Environmental Health Perspectives. 125, 8, 11 p., 087012.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Possible involvement of the glucocorticoid receptor (NR3C1) and selected NR3C1 gene variants in regulation of human testicular function
Nordkap, L., Almstrup, Kristian, Nielsen, J. E., Bang, A. K., Priskorn, L., Krause, M., Holmboe, S. A., Winge, S. B., Egeberg Palme, D. L., Mørup, N., Petersen, Jørgen Holm, Juul, A., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Jørgensen, N., Nov 2017, In: Andrology. 5, 6, p. 1105-1114 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clinical, genetic, biochemical, and testicular biopsy findings among 1,213 men evaluated for infertility
Olesen, I. A., Andersson, A., Aksglaede, L., Skakkebæk, Niels Erik, Rajpert-De Meyts, E., Jørgensen, N. & Juul, Anders, Jan 2017, In: Fertility and Sterility. 107, 1, p. 74-82.e7Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Histopathological Evaluation of Testicular Biopsy
Rajpert-de Meyts, E., Grigor, K. M. & Skakkebæk, Niels Erik, 2017, Endocrinology of the Testis and Male Reproduction. SimoniIlpo, M. & Huhtaniemi, I. (eds.). p. 1-20 (Endocrinology of the Testis and Male Reproduction).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Sperm counts, testicular cancers, and the environment
Skakkebæk, Niels Erik, 10 Oct 2017, In: B M J. 359, j4517.Research output: Contribution to journal › Editorial › Research
- Published
Is human fecundity changing? A discussion of research and data gaps precluding us from having an answer
Smarr, M. M., Sapra, K. J., Gemmill, A., Kahn, L. G., Wise, L. A., Lynch, C. D., Factor-Litvak, P., Mumford, S. L., Skakkebæk, Niels Erik, Slama, R., Lobdell, D. T., Stanford, J. B., Jensen, T. K., Boyle, E. H., Eisenberg, M. L., Turek, P. J., Sundaram, R., Thoma, M. E. & Buck Louis, G. M., 2017, In: Human Reproduction. 32, 3, p. 499-504Research output: Contribution to journal › Comment/debate › Research
- Published
Experimentally induced testicular dysgenesis syndrome originates in the masculinization programming window
van den Driesche, S., Kilcoyne, K. R., Wagner, I., Rebourcet, D., Boyle, A., Mitchell, R., McKinnell, C., Macpherson, S., Donat, R., Shukla, C. J., Jorgensen, A., Meyts, E. R., Skakkebæk, Niels Erik & Sharpe, R. M., 2017, In: JCI insight. 2, 6, 20 p., e91204.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Endocrine disrupters: we need research, biomonitoring and action
Andersson, A., Bay, K., Frederiksen, H. & Skakkebæk, Niels Erik, Jul 2016, In: Andrology. 4, 4, p. 556-60 5 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Country-specific chemical signatures of persistent organic pollutants (POPs) in breast milk of French, Danish and Finnish women
Antignac, J. P., Main, Katharina Maria, Virtanen, H. E., Boquien, C. Y., Marchand, P., Venisseau, A., Guiffard, I., Bichon, E., Wohlfahrt-Veje, C., Legrand, S., Boscher, C., Skakkebæk, Niels Erik, Toppari, J. & Le Bizec, B., Nov 2016, In: Environmental Pollution. 218, p. 728-738 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 35319116
Most downloads
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318
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EDC IMPACT: Chemical UV filters can affect human sperm function in a progesterone-like manner
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
215
downloads
Prenatal exposure to antifungal medication may change anogenital distance in male offspring: a preliminary study
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
215
downloads
Variations in repeated serum concentrations of UV filters, phthalates, phenols and parabens during pregnancy
Research output: Contribution to journal › Journal article › Research › peer-review
Published