Niels Erik Skakkebæk
Affiliate Professor
- 2008
- Published
Testicular dysgenesis syndrome: mechanistic insights and potential new downstream effects
Sharpe, R. M. & Skakkebæk, Niels Erik, 2008, In: Fertility and Sterility. 89, 2 Suppl, p. e33-e38Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Concentrations of persistent organochlorine compounds in human milk and placenta are higher in Denmark than in Finland
Shen, H., Main, K. M., Andersson, A. M., Damgaard, I. N., Virtanen, H. E., Toppari, J., Schramm, K. W. & Skakkebæk, Niels Erik, 2008, In: Human Reproduction. 23, 1, p. 201-210 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mere Testikelkræft og dårlig sædkvalitet
Skakkebæk, Niels Erik, 2008, In: Tidsskrift for Den norske lægeforening. 128, p. 554-554Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Testicular dysgenesis syndrome and the origin of carcinoma in situ testis
Sonne, Si Brask, Kristensen, D. M., Novotny, G. W., Olesen, I. A., Nielsen, J. E., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Leffers, H., 2008, In: International Journal of Andrology. 31, 2, p. 275-87 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2007
- Published
High normal testosterone levels in infants with non-mosaic Klinefelter's syndrome
Aksglaede, L., Petersen, Jørgen Holm, Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 2007, In: European Journal of Endocrinology. 157, 3, p. 345-50 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Primary testicular failure in Klinefelter's syndrome: the use of bivariate luteinizing hormone-testosterone reference charts
Aksglaede, L., Andersson, A., Jørgensen, N., Jensen, T. K., Carlsen, E., McLachlan, R. I., Skakkebæk, Niels Erik, Petersen, Jørgen Holm & Juul, Anders, 1 Feb 2007, In: Clinical Endocrinology. 66, 2, p. 276-81 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improved gene expression signature of testicular carcinoma in situ
Almstrup, Kristian, Leffers, H., Lothe, R. A., Skakkebæk, Niels Erik, Sonne, Si Brask, Nielsen, J. E., Rajpert-De Meyts, E. & Skotheim, R. I., 2007, In: International Journal of Andrology. 30, 4, p. 292-303Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secular decline in male testosterone and sex hormone binding globulin serum levels in Danish population surveys
Andersson, A., Jensen, T. K., Juul, Anders, Petersen, Jørgen Holm, Jørgensen, T. & Skakkebæk, Niels Erik, 1 Dec 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 12, p. 4696-705 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin-like factor 3 levels in cord blood and serum from children: effects of age, postnatal hypothalamic-pituitary-gonadal axis activation, and cryptorchidism
Bay, K., Virtanen, H. E., Hartung, S., Ivell, R., Main, Katharina Maria, Skakkebæk, Niels Erik, Andersson, A., Toppari, J. & Nordic Cryptorchidism Study Group, N. C. S. G., 1 Oct 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 10, p. 4020-7 8 p.Research output: Contribution to journal › Journal article › Research
- Published
Metabolism of phthalates in humans
Frederiksen, H., Skakkebæk, Niels Erik & Andersson, A., 1 Jul 2007, In: Molecular Nutrition & Food Research. 51, 7, p. 899-911 13 p.Research output: Contribution to journal › Journal article › Research
- Published
Self-rated health and semen quality among 3,457 young Danish men
Jensen, T. K., Jørgensen, N., Asklund, C., Carlsen, E., Kristensen, T. S., Holm, M., Skakkebæk, Niels Erik & Jensen, T. K., 1 Nov 2007, In: Fertility and Sterility. 88, 5, p. 1366-73 8 p.Research output: Contribution to journal › Journal article › Research
- Published
Fertility treatment and reproductive health of male offspring: a study of 1,925 young men from the general population
Jensen, T. K., Jørgensen, N., Asklund, C., Carlsen, E., Holm, M., Skakkebæk, Niels Erik & Jensen, T. K., 1 Mar 2007, In: American Journal of Epidemiology. 165, 5, p. 583-90 8 p.Research output: Contribution to journal › Journal article › Research
- Published
Testicular dysgenesis syndrome and carcinoma in situ of the testes
Joensen, Ulla Nordström, Jorgensen, N. & Skakkebæk, Niels Erik, Aug 2007, In: Nature Clinical Practice Urology. 4, 8, p. 402-403 2 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Preserved fertility in a non-mosaic Klinefelter patient with a mutation in the fibroblast growth factor receptor 3 gene: case report
Juul, Anders, Aksglaede, L., Lund, Allan Meldgaard, Duno, M., Skakkebæk, Niels Erik & Rajpert-De Meyts, E., 2007, In: Human Reproduction. 22, 7, p. 1907-11 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Age at voice break in Danish boys: effects of pre-pubertal body mass index and secular trend
Juul, Anders, Magnusdottir, S., Scheike, T., Prytz, S. & Skakkebæk, Niels Erik, 1 Dec 2007, In: International Journal of Andrology. 30, 6, p. 537-42 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
European consensus conference on diagnosis and treatment of germ cell cancer: a report of the second meeting of the European Germ Cell Cancer Consensus Group (EGCCCG): part II
Krege, S., Beyer, J., Souchon, R., Albers, P., Albrecht, W., Algaba, F., Bamberg, M., Bodrogi, I., Bokemeyer, C., Cavallin-Ståhl, E., Classen, J., Clemm, C., Cohn-Cedermark, G., Culine, S., Daugaard, G., De Mulder, P. H. M., De Santis, M., de Wit, M., de Wit, R., Derigs, H. G. & 63 others, , 2007, In: European Urology. 53, 3, p. 497-513 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
European consensus conference on diagnosis and treatment of germ cell cancer: a report of the second meeting of the European Germ Cell Cancer Consensus group (EGCCCG): part I
Krege, S., Beyer, J., Souchon, R., Albers, P., Albrecht, W., Algaba, F., Bamberg, M., Bodrogi, I., Bokemeyer, C., Cavallin-Ståhl, E., Classen, J., Clemm, C., Cohn-Cedermark, G., Culine, S., Daugaard, G., De Mulder, P. H. M., De Santis, M., de Wit, M., de Wit, R., Derigs, H. G. & 63 others, , 2007, In: European Urology. 53, 3, p. 478-496 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced serum testosterone levels in infant boys conceived by intracytoplasmic sperm injection
Mau Kai, C., Main, Katharina Maria, Andersen, A. N., Loft, A., Skakkebæk, Niels Erik & Juul, Anders, 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 7, p. 2598-603 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analysis of gene expression in normal and neoplastic human testis: new roles of RNA
Novotny, G. W., Nielsen, J. E., Sonne, Si Brask, Skakkebæk, Niels Erik, Rajpert-De Meyts, E., Leffers, H. & Sonne, Si Brask, 2007, In: International Journal of Andrology. 30, 4, p. 316-327Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Translational repression of E2F1 mRNA in carcinoma in situ and normal testis correlates with expression of the miR-17-92 cluster
Novotny, G. W., Sonne, Si Brask, Nielsen, J. E., Jonstrup, S. P., Hansen, M. A., Skakkebæk, Niels Erik, Rajpert-De Meyts, E., Kjems, J. & Leffers, H., 2007, In: Cell Death and Differentiation. 14, 4, p. 879-82 3 p.Research output: Contribution to journal › Letter › Research
- Published
Environment, testicular dysgenesis and carcinoma in situ testis
Olesen, I. A., Sonne, Si Brask, Hoei-Hansen, C. E., Rajpert-DeMeyts, E. & Skakkebæk, Niels Erik, 2007, In: Best Practice & Research: Clinical Endocrinology & Metabolism. 21, 3, p. 462-78 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changes in the profile of simple mucin-type O-glycans and polypeptide GalNAc-transferases in human testis and testicular neoplasms are associated with germ cell maturation and tumour differentiation
Rajpert-De Meyts, E., Poll, S. N., Goukasian, I., Jeanneau, C., Herlihy, A. S., Bennett, Eric Paul, Skakkebæk, Niels Erik, Clausen, Henrik, Giwercman, A. & Mandel, Ulla, 2007, In: Virchows Archiv. 451, 4, p. 805-14 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Origin of testicular germ cell neoplasia: The role of sex chromosomes
Rajpert-De Meyts, E., Ottesen, A. M., Høi-Hansen, Christina Engel, Sonne, Si Brask, Leffers, H. & Skakkebæk, Niels Erik, 1 Jan 2007, The Y Chromosome and Male Germ Cell Biology in Health and Diseases. World Scientific Publishing Co., p. 289-308 20 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Testicular cancer trends as 'whistle blowers' of testicular developmental problems in populations
Skakkebæk, Niels Erik, Rajpert-De Meyts, E., Jørgensen, N., Main, Katharina Maria, Leffers, H., Andersson, A., Juul, Anders, Jensen, T. K. & Toppari, J., 2007, In: International Journal of Andrology. 30, 4, p. 198-204; discussion 204-5Research output: Contribution to journal › Review › Research
- Published
Serum sex hormone-binding globulin levels in healthy children and girls with precocious puberty before and during gonadotropin-releasing hormone agonist treatment
Sørensen, K., Andersson, A. M., Skakkebæk, Niels Erik & Juul, Anders, 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 8, p. 3189-96 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development and descent of the testis in relation to cryptorchidism
Virtanen, H. E., Cortes, Dina, Rajpert-De Meyts, E., Ritzén, E. M., Nordenskjöld, A., Skakkebæk, Niels Erik & Toppari, J., 1 May 2007, In: Acta Paediatrica. 96, 5, p. 622-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Natural history of seminiferous tubule degeneration in Klinefelter syndrome
Aksglaede, L., Wikström, A. M., Rajpert-De Meyts, E., Dunkel, L., Skakkebæk, Niels Erik & Juul, Anders, 2006, In: Human Reproduction Update. 12, 1, p. 39-48 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The sensitivity of the child to sex steroids: possible impact of exogenous estrogens
Aksglaede, L., Juul, Anders, Leffers, H., Skakkebæk, Niels Erik & Andersson, A., 2006, In: Human Reproduction Update. 12, 4, p. 341-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
From embryonic stem cells to testicular germ cell cancer-- should we be concerned?
Almstrup, Kristian, Sonne, Si Brask, Hoei-Hansen, C. E., Ottesen, A. M., Nielsen, J. E., Skakkebæk, Niels Erik, Leffers, H. & Rajpert-De Meyts, E., 2006, In: International Journal of Andrology. 29, 1, p. 211-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Testicular dysgenesis syndrome: possible role of endocrine disrupters
Bay, K., Asklund, C., Skakkebæk, Niels Erik & Andersson, A., 1 Mar 2006, In: Best Practice & Research: Clinical Endocrinology & Metabolism. 20, 1, p. 77-90 14 p.Research output: Contribution to journal › Journal article › Research
- Published
A prospective study of serum insulin-like growth factor I (IGF-I) and IGF-binding protein-3 in 942 healthy infants: associations with birth weight, gender, growth velocity, and breastfeeding
Chellakooty, M., Juul, A., Boisen, K. A., Damgaard, I. N., Kai, C. M., Schmidt, I. M., Petersen, Jørgen Holm, Skakkebæk, Niels Erik & Main, K. M., 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 3, p. 820-826 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Serum levels of activin A and inhibin A are not related to the increased susceptibility to pre-eclampsia in type I diabetic pregnancies
Ekbom, P., Damm, Peter, Andersson, A., Skakkebæk, Niels Erik, Feldt-Rasmussen, Ulla & Mathiesen, Elisabeth, 1 Jan 2006, In: Acta Obstetricia et Gynecologica Scandinavica. 85, 2, p. 143-7 5 p.Research output: Contribution to journal › Journal article › Research
- Published
Identification and expression profiling of 10 novel spermatid expressed CYPT genes
Hansen, M. A., Nielsen, J. E., Tanaka, M., Almstrup, Kristian, Skakkebæk, Niels Erik & Leffers, H., May 2006, In: Molecular Reproduction and Development. 73, 5, p. 568-579 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pubertal development in Danish children: comparison of recent European and US data
Juul, Anders, Teilmann, Grete Katrine, Scheike, T. H., Hertel, N., Holm, Kirsten, Laursen, E., Main, Katharina Maria & Skakkebæk, Niels Erik, 2006, In: International Journal of Andrology. 29, 1, p. 247-55; discussion 286-90Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased expression of alpha- and beta-globin mRNAs at the pituitary following exposure to estrogen during the critical period of neonatal sex differentiation in the rat
Leffers, H., Navarro, V. M., Nielsen, J. E., Mayen, A., Pinilla, L., Dalgaard, M., Malagon, M. M., Castaño, J. P., Skakkebæk, Niels Erik, Aguilar, E. & Tena-Sempere, M., 1 Apr 2006, In: Journal of Steroid Biochemistry and Molecular Biology. 99, 1, p. 33-43 11 p.Research output: Contribution to journal › Journal article › Research
- Published
Human breast milk contamination with phthalates and alterations of endogenous reproductive hormones in infants three months of age
Main, Katharina Maria, Mortensen, G. K., Kaleva, M. M., Boisen, K. A., Damgaard, I. N., Chellakooty, M., Schmidt, I. M., Suomi, A., Virtanen, H. E., Petersen, J. H., Andersson, A., Toppari, J. & Skakkebæk, Niels Erik, 2006, In: Environmental Health Perspectives. 114, 2, p. 270-276 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is human fecundity declining?
Skakkebæk, Niels Erik, Jørgensen, N., Main, Katharina Maria, Rajpert-De Meyts, E., Leffers, H., Andersson, A., Juul, Anders, Carlsen, E., Mortensen, G. K., Jensen, T. K. & Toppari, J., 1 Feb 2006, In: International Journal of Andrology. 29, 1, p. 2-11 10 p.Research output: Contribution to journal › Journal article › Research
- Published
CDH1 (E-cadherin) in testicular germ cell neoplasia: suppressed translation of mRNA in pre-invasive carcinoma in situ but increased protein levels in advanced tumours
Sonne, Si Brask, Hoei-Hansen, C. E., Nielsen, J. E., Herlihy, A. S., Andersson, A., Almstrup, Kristian, Daugaard, G., Skakkebæk, Niels Erik, Leffers, H., Rajpert-De Meyts, E., Sonne, S. B., Hoei-Hansen, C. E., Nielsen, J. E., Herlihy, A. S., Andersson, A., Almstrup, K., Daugaard, G., Skakkebæk, Niels Erik, Leffers, H. & Rajpert-De Meyts, E., 2006, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 114, 7-8, p. 549-58 10 p.Research output: Contribution to journal › Journal article › Research
- Published
Identity of M2A (D2-40) antigen and gp36 (Aggrus, T1A-2, podoplanin) in human developing testis, testicular carcinoma in situ and germ-cell tumours
Sonne, Si Brask, Herlihy, A. S., Hoei-Hansen, C. E., Nielsen, J. E., Almstrup, Kristian, Skakkebæk, Niels Erik, Marks, A., Leffers, H. & Rajpert-De Meyts, E., 2006, In: Virchows Archiv. 449, 2, p. 200-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Genome-wide gene expression profiling of testicular carcinoma in situ progression into overt tumours
Almstrup, Kristian, Høi-Hansen, Christina Engel, Nielsen, J. E., Wirkner, U., Ansorge, W., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Leffers, H., 23 May 2005, In: British Journal of Cancer. 92, 10, p. 1934-1941 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic and gene expression signature of the pre-invasive testicular carcinoma in situ
Almstrup, Kristian, Ottesen, A. M., Sonne, Si Brask, Hoei-Hansen, C. E., Leffers, H., Rajpert-De Meyts, E. & Skakkebæk, Niels Erik, 2005, In: Cell and Tissue Research. 322, 1, p. 159-65 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Behandling og udredning af mandlig infertilitet og hypogonadisme
Carlsen, E., Jørgensen, N., Juul, Anders & Skakkebæk, Niels Erik, 2005, In: Maanedsskrift for Praktisk Laegegerning. 83, p. 1239-49 10 p.Research output: Contribution to journal › Review › Research
- Published
Stem cell pluripotency factor NANOG is expressed in human fetal gonocytes, testicular carcinoma in situ and germ cell tumours
Hoei-Hansen, C. E., Almstrup, Kristian, Nielsen, J. E., Sonne, Si Brask, Graem, N., Skakkebæk, Niels Erik, Leffers, H. & Rajpert-De Meyts, E., 2005, In: Histopathology. 47, 1, p. 48-56 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A subfertile patient diagnosed with testicular carcinoma in situ by immunocytological staining for AP-2γ in semen samples: Case report
Høi-Hansen, Christina Engel, Rajpert-De Meyts, E., Carlsen, E., Almstrup, Kristian, Leffers, H. & Skakkebæk, Niels Erik, Mar 2005, In: Human Reproduction. 20, 3, p. 579-582 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin-like growth factor I (IGF-I) and IGF-binding protein 3 as diagnostic markers of growth hormone deficiency in infancy
Jensen, R. B., Jeppesen, K. A., Vielwerth, S., Michaelsen, K. F., Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 2005, In: Hormone Research. 63, 1, p. 15-21 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prevalence and incidence of precocious pubertal development in Denmark: an epidemiologic study based on national registries
Teilmann, Grete Katrine, Pedersen, C., Jensen, T. K., Skakkebæk, Niels Erik & Juul, Anders, 2005, In: Pediatrics. 116, 6, p. 1323-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
Analysis of cell-type-specific gene expression during mouse spermatogenesis
Almstrup, Kristian, Nielsen, J. E., Hansen, M. A., Tanaka, M., Skakkebæk, Niels Erik & Leffers, H., Jun 2004, In: Biology of Reproduction. 70, 6, p. 1751-1761 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Embryonic stem cell-like features of testicular carcinoma in situ revealed by genome-wide gene expression profiling
Almstrup, Kristian, Høi-Hansen, Christina Engel, Wirkner, U., Blake, J., Schwager, C., Ansorge, W., Nielsen, J. E., Skakkebæk, Niels Erik, Rajpert-De Meyts, E. & Leffers, H., 15 Jul 2004, In: Cancer Research. 64, 14, p. 4736-4743 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A longitudinal study of intrauterine growth and the placental growth hormone (GH)-insulin-like growth factor I axis in maternal circulation: association between placental GH and fetal growth
Chellakooty, M., Vangsgaard, K., Larsen, T., Scheike, T., Falck-Larsen, J., Legarth, J., Andersson, A. M., Main, Katharina Maria, Skakkebæk, Niels Erik & Juul, Anders, 1 Jan 2004, In: Journal of Clinical Endocrinology and Metabolism. 89, 1, p. 384-91 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of genes differentially expressed in testes containing carcinoma in situ
Høi-Hansen, Christina Engel, Nielsen, J. E., Almstrup, Kristian, Hansen, M. A., Skakkebæk, Niels Erik, Rajpert-DeMeyts, E. & Leffers, H., Jun 2004, In: Molecular Human Reproduction. 10, 6, p. 423-431 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 35319116
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EDC IMPACT: Chemical UV filters can affect human sperm function in a progesterone-like manner
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Prenatal exposure to antifungal medication may change anogenital distance in male offspring: a preliminary study
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Variations in repeated serum concentrations of UV filters, phthalates, phenols and parabens during pregnancy
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Published